JP2001506629A - 医療用抗酸化剤として使用するための１７α−ジヒドロエキレニン - Google Patents

医療用抗酸化剤として使用するための１７α−ジヒドロエキレニン

Info

Publication number
JP2001506629A
JP2001506629A JP52680598A JP52680598A JP2001506629A JP 2001506629 A JP2001506629 A JP 2001506629A JP 52680598 A JP52680598 A JP 52680598A JP 52680598 A JP52680598 A JP 52680598A JP 2001506629 A JP2001506629 A JP 2001506629A
Authority
JP
Japan
Prior art keywords
dihydroequilenin
disease
pharmaceutically acceptable
salts
free radicals
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP52680598A
Other languages
English (en)
Japanese (ja)
Inventor
アデルマン，スティーブン・ジェイ
プロジアレック，ドロシー・ヘレン
クラーク，ドナルド・ユージーン
Original Assignee
アメリカン・ホーム・プロダクツ・コーポレイション
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by アメリカン・ホーム・プロダクツ・コーポレイション filed Critical アメリカン・ホーム・プロダクツ・コーポレイション
Publication of JP2001506629A publication Critical patent/JP2001506629A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP52680598A 1996-12-09 1997-12-05 医療用抗酸化剤として使用するための１７α−ジヒドロエキレニン Pending JP2001506629A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US76263496A 1996-12-09 1996-12-09
US08/762,634 1996-12-09
PCT/US1997/022155 WO1998025627A1 (en) 1996-12-09 1997-12-05 17α-DIHYDROEQUILENIN FOR USE AS A MEDICAL ANTIOXIDANT

Publications (1)

Publication Number Publication Date
JP2001506629A true JP2001506629A (ja) 2001-05-22

Family

ID=25065657

Family Applications (1)

Application Number Title Priority Date Filing Date
JP52680598A Pending JP2001506629A (ja) 1996-12-09 1997-12-05 医療用抗酸化剤として使用するための１７α−ジヒドロエキレニン

Country Status (13)

Country Link
EP (1) EP0946182A1 (es)
JP (1) JP2001506629A (es)
KR (1) KR20000069346A (es)
CN (1) CN1239890A (es)
AR (1) AR010336A1 (es)
AU (1) AU743519B2 (es)
BR (1) BR9714382A (es)
CA (1) CA2272089A1 (es)
HU (1) HUP0000570A3 (es)
IL (1) IL130069A0 (es)
NZ (1) NZ336341A (es)
WO (1) WO1998025627A1 (es)
ZA (1) ZA9711053B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6271221B1 (en) * 1996-12-10 2001-08-07 American Home Products Corporation Use of equilenin as an antioxidant
DE10154221A1 (de) * 2001-11-07 2003-05-15 Max Delbrueck Centrum Mittel zur Behandlung von Läsionen des Nervensystems

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4338314C1 (de) * 1993-11-10 1995-03-30 Jenapharm Gmbh Pharmazeutische Präparate zur Prophylaxe und Therapie radikalvermittelter Zellschädigungen

Also Published As

Publication number Publication date
KR20000069346A (ko) 2000-11-25
WO1998025627A1 (en) 1998-06-18
IL130069A0 (en) 2000-02-29
ZA9711053B (en) 1999-06-09
CN1239890A (zh) 1999-12-29
AU5464498A (en) 1998-07-03
AU743519B2 (en) 2002-01-31
HUP0000570A3 (en) 2000-12-28
BR9714382A (pt) 2000-05-16
CA2272089A1 (en) 1998-06-18
NZ336341A (en) 2002-02-01
HUP0000570A2 (hu) 2000-10-28
EP0946182A1 (en) 1999-10-06
AR010336A1 (es) 2000-06-07

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