JP2001503388A5 - - Google Patents
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- Publication number
- JP2001503388A5 JP2001503388A5 JP1998511072A JP51107298A JP2001503388A5 JP 2001503388 A5 JP2001503388 A5 JP 2001503388A5 JP 1998511072 A JP1998511072 A JP 1998511072A JP 51107298 A JP51107298 A JP 51107298A JP 2001503388 A5 JP2001503388 A5 JP 2001503388A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9604253A SE9604253D0 (sv) | 1996-11-20 | 1996-11-20 | New manufacturing process metoprolol |
| SE9604253-6 | 1996-11-20 | ||
| PCT/SE1997/001926 WO1998022426A1 (en) | 1996-11-20 | 1997-11-18 | New manufacturing process of metoprolol |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2001503388A JP2001503388A (ja) | 2001-03-13 |
| JP2001503388A5 true JP2001503388A5 (enExample) | 2005-07-14 |
| JP4039640B2 JP4039640B2 (ja) | 2008-01-30 |
Family
ID=20404680
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP51107298A Expired - Fee Related JP4039640B2 (ja) | 1996-11-20 | 1997-11-18 | メトプロロールの新規な製造方法 |
Country Status (35)
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050107635A1 (en) * | 2003-11-14 | 2005-05-19 | Mehra Janakraj K. | Metoprolol manufacturing process |
| CA2640876A1 (en) * | 2005-12-23 | 2007-12-13 | Medichem, S.A. | Process for the preparation of metoprolol and its salts |
| US20080107726A1 (en) * | 2006-11-01 | 2008-05-08 | Pramod Kharwade | Compositions comprising beta-adrenergic receptor antagonists and diuretics |
| CN101607918B (zh) * | 2008-06-16 | 2014-02-19 | 北京德众万全药物技术开发有限公司 | 一种美托洛尔的制备方法 |
| US8877930B2 (en) * | 2009-11-04 | 2014-11-04 | Massachusetts Institute Of Technology | Continuous flow synthesis of amino alcohols using microreactors |
| US8680303B2 (en) | 2010-03-01 | 2014-03-25 | Massachusetts Institute Of Technology | Epoxidation catalysts |
| CN102381995B (zh) * | 2010-08-31 | 2015-04-15 | 扬子江药业集团北京海燕药业有限公司 | 美托洛尔的制备方法 |
| CN102432476A (zh) * | 2010-09-29 | 2012-05-02 | 湖南康普医药研究院 | 一种规模化制备琥珀酸美托洛尔的方法 |
| CN102503843B (zh) * | 2011-10-28 | 2013-10-23 | 山东阿如拉药物研究开发有限公司 | 一种美托洛尔盐的制备方法 |
| KR101379383B1 (ko) * | 2012-03-23 | 2014-04-02 | 주식회사 알에스텍 | 고순도 ⒮―메토프롤롤의 제조방법 |
| CN103980134B (zh) * | 2014-05-30 | 2015-09-30 | 安徽省新星药物开发有限责任公司 | 一种琥珀酸s-美托洛尔的制备方法 |
| CN105820057B (zh) * | 2016-04-22 | 2017-09-29 | 上海应用技术学院 | 一种制备美多心安的方法 |
| CN106543015A (zh) * | 2016-11-07 | 2017-03-29 | 上海应用技术大学 | 一种美多心安的制备方法 |
| CN108299279B (zh) * | 2018-02-09 | 2021-03-23 | 北京梅尔森医药技术开发有限公司 | 取代芳基胺醇化合物及其制备方法和用途 |
| EP3768378B1 (en) | 2018-03-22 | 2025-08-06 | InCarda Therapeutics, Inc. | A novel method to slow ventricular rate |
| CN111018724B (zh) * | 2019-12-27 | 2022-11-08 | 江西美晶科技有限公司 | 一种美托洛尔及其制备方法 |
| CN112645827A (zh) * | 2020-12-25 | 2021-04-13 | 浙江普洛家园药业有限公司 | 一种连续合成美多心安及其盐的方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2011584A6 (es) * | 1989-05-26 | 1990-01-16 | Esteve Quimica Sa | Procedimiento industrial para la obtencion de una ariloxipropanolamina. |
| EP0677291A3 (en) | 1991-03-18 | 1996-08-07 | Sepracor Inc | Composition and method containing optically pure S-metoprolol. |
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1996
- 1996-11-18 NZ NZ335213A patent/NZ335213A/en unknown
- 1996-11-20 SE SE9604253A patent/SE9604253D0/xx unknown
- 1996-11-20 US US08/973,144 patent/US6252113B1/en not_active Expired - Lifetime
-
1997
- 1997-10-23 TW TW086115698A patent/TW412513B/zh active
- 1997-11-06 ZA ZA9710005A patent/ZA9710005B/xx unknown
- 1997-11-12 SA SA97180599A patent/SA97180599B1/ar unknown
- 1997-11-13 IN IN3275DE1997 patent/IN187175B/en unknown
- 1997-11-18 CN CN97199796A patent/CN1128786C/zh not_active Expired - Lifetime
- 1997-11-18 CA CA002269941A patent/CA2269941A1/en not_active Abandoned
- 1997-11-18 KR KR1019997004401A patent/KR100544560B1/ko not_active Expired - Fee Related
- 1997-11-18 SK SK564-99A patent/SK281990B6/sk unknown
- 1997-11-18 ID IDW990343D patent/ID21505A/id unknown
- 1997-11-18 ES ES97913641T patent/ES2193365T3/es not_active Expired - Lifetime
- 1997-11-18 IL IL12974797A patent/IL129747A/xx not_active IP Right Cessation
- 1997-11-18 EE EEP199900202A patent/EE03761B1/xx not_active IP Right Cessation
- 1997-11-18 UA UA99042412A patent/UA66769C2/uk unknown
- 1997-11-18 WO PCT/SE1997/001926 patent/WO1998022426A1/en not_active Ceased
- 1997-11-18 RU RU99109477/04A patent/RU2210565C2/ru not_active IP Right Cessation
- 1997-11-18 EP EP97913641A patent/EP0942899B1/en not_active Expired - Lifetime
- 1997-11-18 DK DK97913641T patent/DK0942899T3/da active
- 1997-11-18 EG EG122697A patent/EG21158A/xx active
- 1997-11-18 BR BR9713370A patent/BR9713370A/pt not_active Application Discontinuation
- 1997-11-18 DE DE69719788T patent/DE69719788T2/de not_active Expired - Fee Related
- 1997-11-18 CZ CZ991744A patent/CZ174499A3/cs unknown
- 1997-11-18 JP JP51107298A patent/JP4039640B2/ja not_active Expired - Fee Related
- 1997-11-18 AU AU50776/98A patent/AU728270B2/en not_active Ceased
- 1997-11-18 TR TR1999/01115T patent/TR199901115T2/xx unknown
- 1997-11-18 AT AT97913641T patent/ATE234273T1/de not_active IP Right Cessation
- 1997-11-18 HU HU0002445A patent/HUP0002445A3/hu unknown
- 1997-11-18 PT PT97913641T patent/PT942899E/pt unknown
- 1997-11-18 PL PL333541A patent/PL191392B1/pl not_active IP Right Cessation
- 1997-11-19 MY MYPI97005544A patent/MY119303A/en unknown
- 1997-11-19 AR ARP970105420A patent/AR010069A1/es unknown
-
1999
- 1999-04-26 IS IS5034A patent/IS1964B/is unknown
- 1999-05-19 NO NO19992401A patent/NO311352B1/no unknown