JP2001502521A5 - - Google Patents

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Publication number
JP2001502521A5
JP2001502521A5 JP1997539046A JP53904697A JP2001502521A5 JP 2001502521 A5 JP2001502521 A5 JP 2001502521A5 JP 1997539046 A JP1997539046 A JP 1997539046A JP 53904697 A JP53904697 A JP 53904697A JP 2001502521 A5 JP2001502521 A5 JP 2001502521A5
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JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP1997539046A
Other languages
English (en)
Japanese (ja)
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JP2001502521A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US1997/006931 external-priority patent/WO1997041232A1/en
Publication of JP2001502521A publication Critical patent/JP2001502521A/ja
Publication of JP2001502521A5 publication Critical patent/JP2001502521A5/ja
Ceased legal-status Critical Current

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JP09539046A 1996-04-26 1997-04-25 インターロイキン―15の拮抗剤 Ceased JP2001502521A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1663496P 1996-04-26 1996-04-26
US60/016,634 1996-04-26
PCT/US1997/006931 WO1997041232A1 (en) 1996-04-26 1997-04-25 Antagonists of interleukin-15

Publications (2)

Publication Number Publication Date
JP2001502521A JP2001502521A (ja) 2001-02-27
JP2001502521A5 true JP2001502521A5 (https=) 2004-11-25

Family

ID=21778153

Family Applications (1)

Application Number Title Priority Date Filing Date
JP09539046A Ceased JP2001502521A (ja) 1996-04-26 1997-04-25 インターロイキン―15の拮抗剤

Country Status (8)

Country Link
US (1) US6001973A (https=)
EP (1) EP0927254B1 (https=)
JP (1) JP2001502521A (https=)
AT (1) ATE298367T1 (https=)
CA (1) CA2252557A1 (https=)
DE (1) DE69733610T2 (https=)
ES (1) ES2243995T3 (https=)
WO (1) WO1997041232A1 (https=)

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Publication number Priority date Publication date Assignee Title
US11845783B2 (en) 2010-09-21 2023-12-19 Altor BioScience, LLC. Multimeric IL-15 soluble fusion molecules and methods of making and using same

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US20060134140A1 (en) * 2001-04-12 2006-06-22 Dana Lasko Compositions and methods for treating tumor spreading
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EP2366787B1 (en) 2006-01-13 2019-12-11 The Government Of The U.S.A, As Represented By The Secretary, Dept. Of Health And Human Services Codon optimized IL-15 and IL-15R-Alpha genes for expression in mammalian cells
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US20110020269A1 (en) * 2007-05-08 2011-01-27 Beth Israel Deaconess Medical Center, Inc. Methods and compositions for modifying t cell immune responses and inflammation
DK2160401T3 (da) * 2007-05-11 2014-10-20 Altor Bioscience Corp Fusionsmolekyler og il-15-varianter
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CA2918119C (en) * 2013-07-19 2022-11-29 Centre Hospitalier Regional Universitaire De Montpellier Targeting of ifn.alpha.2 antagonists to treat autoimmune diseases
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CA3151221C (en) 2014-06-30 2026-01-13 Altor Bioscience Corporation Il-15-based molecules and methods of use thereof
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JP7185530B2 (ja) 2016-06-13 2022-12-07 トルク セラピューティクス, インコーポレイテッド 免疫細胞機能を促進するための方法および組成物
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CU24545B1 (es) 2017-12-29 2021-09-07 Ct Ingenieria Genetica Biotecnologia Péptido antagonista de la actividad de la interleucina-15
JP7273421B2 (ja) 2018-02-21 2023-05-15 ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム ナチュラルキラー細胞の活性化および拡大のための方法ならびにその使用
CA3097625A1 (en) 2018-04-18 2019-10-24 Xencor, Inc. Il-15/il-15ra heterodimeric fc fusion proteins and uses thereof
SG11202010163QA (en) 2018-04-18 2020-11-27 Xencor Inc Pd-1 targeted heterodimeric fusion proteins containing il-15/il-15ra fc-fusion proteins and pd-1 antigen binding domains and uses thereof
KR20210003813A (ko) 2018-04-18 2021-01-12 젠코어 인코포레이티드 IL-15/IL-15Rα Fc-융합 단백질 및 LAG-3 항원 결합 도메인을 함유하는 LAG-3 표적화 이종이량체 융합 단백질
US11505595B2 (en) 2018-04-18 2022-11-22 Xencor, Inc. TIM-3 targeted heterodimeric fusion proteins containing IL-15/IL-15RA Fc-fusion proteins and TIM-3 antigen binding domains
AU2019359475A1 (en) 2018-10-12 2021-05-20 Xencor, Inc. PD-1 targeted IL-15/IL-15Ralpha Fc fusion proteins and uses in combination therapies thereof
CN113438961A (zh) 2018-12-20 2021-09-24 Xencor股份有限公司 含有IL-15/IL-15Rα和NKG2D抗原结合结构域的靶向异二聚体Fc融合蛋白
KR102265430B1 (ko) * 2019-08-20 2021-06-15 주식회사 케어젠 피부 상태 개선 활성을 갖는 펩타이드 및 이의 용도
TW202128757A (zh) 2019-10-11 2021-08-01 美商建南德克公司 具有改善之特性的 PD-1 標靶 IL-15/IL-15Rα FC 融合蛋白
US20230151095A1 (en) 2021-11-12 2023-05-18 Xencor, Inc. Bispecific antibodies that bind to b7h3 and nkg2d
WO2024102636A1 (en) 2022-11-07 2024-05-16 Xencor, Inc. Bispecific antibodies that bind to b7h3 and mica/b
US20250243279A1 (en) 2023-10-17 2025-07-31 Xencor, Inc. Bispecific antibodies that bind to nkp46 and mica/b

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11845783B2 (en) 2010-09-21 2023-12-19 Altor BioScience, LLC. Multimeric IL-15 soluble fusion molecules and methods of making and using same

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