JP2001501471A5 - - Google Patents

Download PDF

Info

Publication number
JP2001501471A5
JP2001501471A5 JP1998515840A JP51584098A JP2001501471A5 JP 2001501471 A5 JP2001501471 A5 JP 2001501471A5 JP 1998515840 A JP1998515840 A JP 1998515840A JP 51584098 A JP51584098 A JP 51584098A JP 2001501471 A5 JP2001501471 A5 JP 2001501471A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP1998515840A
Other languages
English (en)
Japanese (ja)
Other versions
JP2001501471A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US1997/017044 external-priority patent/WO1998013071A1/en
Publication of JP2001501471A publication Critical patent/JP2001501471A/ja
Publication of JP2001501471A5 publication Critical patent/JP2001501471A5/ja
Pending legal-status Critical Current

Links

JP10515840A 1996-09-24 1997-09-24 血管新生の阻害のための遺伝子治療 Pending JP2001501471A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2664196P 1996-09-24 1996-09-24
US60/026,641 1996-09-24
PCT/US1997/017044 WO1998013071A1 (en) 1996-09-24 1997-09-24 Gene therapy for inhibition of angiogenesis

Publications (2)

Publication Number Publication Date
JP2001501471A JP2001501471A (ja) 2001-02-06
JP2001501471A5 true JP2001501471A5 (enExample) 2005-05-12

Family

ID=21833003

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10515840A Pending JP2001501471A (ja) 1996-09-24 1997-09-24 血管新生の阻害のための遺伝子治療

Country Status (9)

Country Link
US (1) US6375929B1 (enExample)
EP (1) EP0928203B1 (enExample)
JP (1) JP2001501471A (enExample)
AT (1) ATE343400T1 (enExample)
AU (1) AU738806B2 (enExample)
CA (1) CA2266419A1 (enExample)
DE (1) DE69736860T2 (enExample)
ES (1) ES2274549T3 (enExample)
WO (1) WO1998013071A1 (enExample)

Families Citing this family (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9723780D0 (en) * 1997-11-12 1998-01-07 Univ Manchester Regulation of ocular angiogenesis
EP1126869B1 (en) 1998-10-28 2008-09-03 Cornell Research Foundation, Inc. Methods for regulating angiogenesis and vascular integrity using the trk receptor ligands bdnf, nt-3 and nt-4
US7393823B1 (en) 1999-01-20 2008-07-01 Oregon Health And Science University HER-2 binding antagonists
US7396810B1 (en) * 2000-08-14 2008-07-08 Oregon Health Sciences University Compositions and methods for treating cancer by modulating HER-2 and EGF receptors
US7625859B1 (en) * 2000-02-16 2009-12-01 Oregon Health & Science University HER-2 binding antagonists
EP1183051A2 (en) * 1999-03-15 2002-03-06 Chiron Corporation Use of recombinant gene delivery vectors for treating or preventing diseases of the eye
US6943153B1 (en) 1999-03-15 2005-09-13 The Regents Of The University Of California Use of recombinant gene delivery vectors for treating or preventing diseases of the eye
US7306799B2 (en) 1999-06-08 2007-12-11 Regeneron Pharmaceuticals, Inc. Use of VEGF inhibitors for treatment of eye disorders
US6833349B2 (en) 1999-06-08 2004-12-21 Regeneron Pharmaceuticals, Inc. Methods of treating inflammatory skin diseases
US7087411B2 (en) 1999-06-08 2006-08-08 Regeneron Pharmaceuticals, Inc. Fusion protein capable of binding VEGF
US7070959B1 (en) 1999-06-08 2006-07-04 Regeneron Pharmaceuticals, Inc. Modified chimeric polypeptides with improved pharmacokinetic properties
US7303746B2 (en) 1999-06-08 2007-12-04 Regeneron Pharmaceuticals, Inc. Methods of treating eye disorders with modified chimeric polypeptides
US6821775B1 (en) * 2000-02-11 2004-11-23 Genvec, Inc. Viral vector encoding pigment epithelium-derived factor
US7653769B2 (en) * 2006-12-14 2010-01-26 International Business Machines Corporation Management of devices connected to infiniband ports
AUPQ592100A0 (en) * 2000-02-29 2000-03-23 Council Of The Queensland Institute Of Medical Research, The A method of treatment and prophylaxis
HUP0300810A2 (hu) * 2000-07-20 2003-08-28 M.G.V.S. Ltd. Mesterséges értranszplantátum, valamint ennek létrehozása és alkalmazása
US7175658B1 (en) 2000-07-20 2007-02-13 Multi-Gene Vascular Systems Ltd. Artificial vascular grafts, their construction and use
WO2002024234A2 (en) * 2000-09-20 2002-03-28 The Regents Of The University Of California Use of recombinant gene delivery vectors for treating or preventing diseases of the eye
GB0109781D0 (en) * 2001-04-20 2001-06-13 Oxford Biomedica Ltd Vector system
US20040062751A1 (en) * 2002-01-17 2004-04-01 Genetix Pharmaceuticals, Inc. Methods for inhibiting angiogenesis
WO2003068155A2 (en) * 2002-02-12 2003-08-21 Vanderbilt University Inhibition of vegf receptor signaling reverses tumor resistance to radiotherapy
US20060234969A1 (en) * 2003-03-07 2006-10-19 Anges Mg, Inc. Compositions and methods for inhibiting inflammation of vessel walls and formation of neointimal hyperplasia
WO2004078786A1 (en) * 2003-03-07 2004-09-16 Anges Mg Inc. Compositions and methods for inhibiting inflammation of vessel walls and formation of neointimal hyperplasia
WO2005016966A2 (en) * 2003-05-16 2005-02-24 Receptor Biologix, Inc. Intron fusion proteins, and methods of identifying and using same
PT1638591E (pt) * 2003-05-29 2013-05-22 Univ Manchester Agonistas de slrp de classe iii para a redução da formação de vasos sanguíneos
US7186699B2 (en) 2003-06-03 2007-03-06 Cell Genesys, Inc. Method for treating cancer by vector-mediated delivery of one or more anti-angiogenic or pro-apoptotic genes
US7399612B2 (en) 2003-06-30 2008-07-15 Regeneron Pharmaceuticals, Inc. VEGF-binding fusion proteins and nucleic acids encoding the same
AU2004268614C1 (en) 2003-08-27 2010-10-28 Ophthotech Corporation Combination therapy for the treatment of ocular neovascular disorders
DE602005027673D1 (de) * 2004-03-05 2011-06-09 Vegenics Pty Ltd Materialien und verfahren für wachstumsfaktorbindende konstrukte
CA2565974A1 (en) * 2004-05-14 2005-12-01 Receptor Biologix, Inc. Cell surface receptor isoforms and methods of identifying and using the same
US20070224194A1 (en) * 2004-05-20 2007-09-27 Ludwig Institute For Cancer Research Methods for Inhibiting Angiogenesis and/or Lymphangiogenesis
EP1789074A4 (en) * 2004-08-09 2009-08-12 Alios Biopharma Inc PROTEASE-RESISTANT HYPERGLYCOSYL SYNTHETIC POLYPEPTIDE VARIANTS, ORAL FORMULATIONS AND METHODS OF USING THE SAME
US7597884B2 (en) 2004-08-09 2009-10-06 Alios Biopharma, Inc. Hyperglycosylated polypeptide variants and methods of use
US7381836B2 (en) * 2004-09-02 2008-06-03 Eastman Chemical Company Optimized liquid-phase oxidation
US7482482B2 (en) 2004-09-02 2009-01-27 Eastman Chemical Company Optimized liquid-phase oxidation
US7608733B2 (en) * 2004-09-02 2009-10-27 Eastman Chemical Company Optimized liquid-phase oxidation
US7507857B2 (en) * 2004-09-02 2009-03-24 Eastman Chemical Company Optimized liquid-phase oxidation
US7741515B2 (en) * 2004-09-02 2010-06-22 Eastman Chemical Company Optimized liquid-phase oxidation
US7692036B2 (en) * 2004-11-29 2010-04-06 Eastman Chemical Company Optimized liquid-phase oxidation
US7371894B2 (en) * 2004-09-02 2008-05-13 Eastman Chemical Company Optimized liquid-phase oxidation
US7390921B2 (en) * 2004-09-02 2008-06-24 Eastman Chemical Company Optimized liquid-phase oxidation
US7495125B2 (en) * 2004-09-02 2009-02-24 Eastman Chemical Company Optimized liquid-phase oxidation
US7582793B2 (en) * 2004-09-02 2009-09-01 Eastman Chemical Company Optimized liquid-phase oxidation
US7568361B2 (en) * 2004-09-02 2009-08-04 Eastman Chemical Company Optimized liquid-phase oxidation
US7589231B2 (en) * 2004-09-02 2009-09-15 Eastman Chemical Company Optimized liquid-phase oxidation
US7692037B2 (en) * 2004-09-02 2010-04-06 Eastman Chemical Company Optimized liquid-phase oxidation
US7504535B2 (en) * 2004-09-02 2009-03-17 Eastman Chemical Company Optimized liquid-phase oxidation
US7683210B2 (en) * 2004-09-02 2010-03-23 Eastman Chemical Company Optimized liquid-phase oxidation
US7608732B2 (en) * 2005-03-08 2009-10-27 Eastman Chemical Company Optimized liquid-phase oxidation
US7586000B2 (en) * 2004-09-02 2009-09-08 Eastman Chemical Company Optimized liquid-phase oxidation
US20060047153A1 (en) * 2004-09-02 2006-03-02 Wonders Alan G Optimized liquid-phase oxidation
US7361784B2 (en) * 2004-09-02 2008-04-22 Eastman Chemical Company Optimized liquid-phase oxidation
US7563926B2 (en) * 2004-09-02 2009-07-21 Eastman Chemical Company Optimized liquid-phase oxidation
US7399882B2 (en) * 2004-09-02 2008-07-15 Eastman Chemical Company Optimized liquid-phase oxidation
US7910769B2 (en) * 2004-09-02 2011-03-22 Eastman Chemical Company Optimized liquid-phase oxidation
ATE470454T1 (de) 2004-09-13 2010-06-15 Genzyme Corp Multimere konstrukte
EP1807106A2 (en) * 2004-10-05 2007-07-18 Oregon Health and Science University Compositions and methods for treating disease
US20090087424A1 (en) * 2004-11-26 2009-04-02 Noriko Miyamoto Modulating Retinal Pigmented Epithelium Permeaion By Inhibiting Or Activating VEGFR-1
US20060116531A1 (en) * 2004-11-29 2006-06-01 Wonders Alan G Modeling of liquid-phase oxidation
US8211864B2 (en) * 2005-01-26 2012-07-03 Medical College Of Georgia Research Institute Compositions and methods for the intracellular disruption of VEGF and VEGFR-2 by intraceptors
EP1877438A2 (en) 2005-02-02 2008-01-16 Regeneron Pharmaceuticals, Inc. Method of treating eye injury with local administration of a vegf inhibitor
CN101184776B (zh) 2005-03-24 2013-04-24 斯路姆基因公司 新型抗胎盘生长因子抗体
US20090170769A1 (en) * 2005-05-13 2009-07-02 Pei Jin Cell surface receptor isoforms and methods of identifying and using the same
US7884232B2 (en) * 2005-06-16 2011-02-08 Eastman Chemical Company Optimized liquid-phase oxidation
US7867490B2 (en) 2005-06-30 2011-01-11 Vib Vzw Treatment of liver cirrhosis and its complications
KR100737286B1 (ko) 2005-08-31 2007-07-13 박기랑 VEGFR 트렁케이티드 cDNA를 함유하는 재조합아데노-연관 바이러스 및 이를 함유하는 암-특이적 유전자치료제
US7358389B2 (en) * 2006-01-04 2008-04-15 Eastman Chemical Company Oxidation system employing internal structure for enhanced hydrodynamics
US7355068B2 (en) 2006-01-04 2008-04-08 Eastman Chemical Company Oxidation system with internal secondary reactor
US9073997B2 (en) * 2007-02-02 2015-07-07 Vegenics Pty Limited Growth factor antagonists for organ transplant alloimmunity and arteriosclerosis
US7871100B2 (en) * 2007-03-27 2011-01-18 Wonderland Nurserygoods Co., Ltd. Collapsible stroller
US20080260820A1 (en) * 2007-04-19 2008-10-23 Gilles Borrelly Oral dosage formulations of protease-resistant polypeptides
MX2011003428A (es) 2008-10-02 2011-07-29 Vib Vzw Inhibicion del factor de crecimiento placentario (plgf) para tratar la leucemia con cromosoma filadelfia positivo.
KR101248912B1 (ko) * 2009-12-31 2013-03-29 한양대학교 산학협력단 항혈관신생 활성을 가지는 재조합 아데노바이러스
DK2601214T3 (en) 2010-08-06 2018-02-05 Genzyme Corp VEGF ANTAGONIST COMPOSITIONS AND APPLICATIONS THEREOF
JO3283B1 (ar) 2011-04-26 2018-09-16 Sanofi Sa تركيب يتضمن أفليبيرسيبت, حمض فولينيك, 5- فلورويوراسيل (5- Fu) وإرينوسيتان (FOLFIRI)
EP2785739B1 (en) 2011-12-01 2017-03-15 ThromboGenics N.V. Improving trabeculectomy outcome
TWI702955B (zh) 2012-05-15 2020-09-01 澳大利亞商艾佛蘭屈澳洲私營有限公司 使用腺相關病毒(aav)sflt-1治療老年性黃斑部退化(amd)
SMT202000088T1 (it) 2013-02-18 2020-03-13 Vegenics Pty Ltd Molecole leganti ligandi e relativi usi
US9914769B2 (en) 2014-07-15 2018-03-13 Kymab Limited Precision medicine for cholesterol treatment
GB201403775D0 (en) 2014-03-04 2014-04-16 Kymab Ltd Antibodies, uses & methods
ES3042252T3 (en) 2014-03-17 2025-11-19 Adverum Biotechnologies Inc Compositions and methods for enhanced gene expression in cone cells
MA40354A (fr) 2014-07-18 2017-05-24 Sanofi Sa Procédé permettant de prédire le résultat d'un traitement avec de l'aflibercept d'un patient suspecté de souffrir d'un cancer
CN114480502A (zh) 2015-03-02 2022-05-13 阿德夫拉姆生物技术股份有限公司 用于将多核苷酸玻璃体内递送到视网膜视锥的组合物和方法
GB2545763A (en) 2015-12-23 2017-06-28 Adverum Biotechnologies Inc Mutant viral capsid libraries and related systems and methods
TWI640536B (zh) 2016-06-20 2018-11-11 克馬伯有限公司 抗體
US11779604B2 (en) 2016-11-03 2023-10-10 Kymab Limited Antibodies, combinations comprising antibodies, biomarkers, uses and methods
US20230372397A1 (en) 2020-10-06 2023-11-23 Iovance Biotherapeutics, Inc. Treatment of nsclc patients with tumor infiltrating lymphocyte therapies

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5240848A (en) 1988-11-21 1993-08-31 Monsanto Company Dna sequences encoding human vascular permeability factor having 189 amino acids
US5332671A (en) 1989-05-12 1994-07-26 Genetech, Inc. Production of vascular endothelial cell growth factor and DNA encoding same
US5194596A (en) * 1989-07-27 1993-03-16 California Biotechnology Inc. Production of vascular endothelial cell growth factor
CN1701814A (zh) * 1992-11-13 2005-11-30 马克斯普朗克科学促进协会 作为血管内皮生长因子受体的f1k-1
ATE281469T1 (de) * 1993-03-25 2004-11-15 Merck & Co Inc Inhibitor des wachstumsfaktors für gefäss- endothelzellen
GB9410534D0 (en) * 1994-05-26 1994-07-13 Lynxvale Ltd Improvements in or relating to growth factor inhibitors

Similar Documents

Publication Publication Date Title
JP2001505109A5 (enExample)
JP2001503840A5 (enExample)
JP2001506057A5 (enExample)
JP2001501471A5 (enExample)
JP2000513715A5 (enExample)
JP2000513159A5 (enExample)
JP2002514054A5 (enExample)
JP2001502986A5 (enExample)
JP2001502086A5 (enExample)
JP2000513709A5 (enExample)
JP2000517136A5 (enExample)
JP2001506269A5 (enExample)
JP2000516200A5 (enExample)
JP2000517167A5 (enExample)
JP2000512134A5 (enExample)
JP2000511540A5 (enExample)
JP2001500658A5 (enExample)
JP2000508289A5 (enExample)
JP2001502002A5 (enExample)
JP2001502915A5 (enExample)
JP2001500552A5 (enExample)
JP2001502448A5 (enExample)
JP2000507538A5 (enExample)
JP2000516211A5 (enExample)
JP2000505733A5 (enExample)