JP2001500408A - 共有結合ヘパリンを含む表面コーティングを介した有意な開通性強化を有するePTFE小直径血管移植片 - Google Patents
共有結合ヘパリンを含む表面コーティングを介した有意な開通性強化を有するePTFE小直径血管移植片Info
- Publication number
- JP2001500408A JP2001500408A JP10513888A JP51388898A JP2001500408A JP 2001500408 A JP2001500408 A JP 2001500408A JP 10513888 A JP10513888 A JP 10513888A JP 51388898 A JP51388898 A JP 51388898A JP 2001500408 A JP2001500408 A JP 2001500408A
- Authority
- JP
- Japan
- Prior art keywords
- biologically active
- hydrophilic
- group
- spacer
- reagent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/507—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials for artificial blood vessels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
- A61L33/0005—Use of materials characterised by their function or physical properties
- A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
- A61L33/0029—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate using an intermediate layer of polymer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
- A61L33/0005—Use of materials characterised by their function or physical properties
- A61L33/0047—Enzymes, e.g. urokinase, streptokinase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
- A61L33/0094—Physical treatment, e.g. plasma treatment
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Surgery (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Materials Engineering (AREA)
- Vascular Medicine (AREA)
- Physics & Mathematics (AREA)
- Plasma & Fusion (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/713,800 | 1996-09-13 | ||
US08/713,800 US6306165B1 (en) | 1996-09-13 | 1996-09-13 | ePTFE small caliber vascular grafts with significant patency enhancement via a surface coating which contains covalently bonded heparin |
PCT/US1997/016163 WO1998010806A1 (en) | 1996-09-13 | 1997-09-11 | ePTFE SMALL CALIBER VASCULAR GRAFTS WITH SIGNIFICANT PATENCY ENHANCEMENT VIA A SURFACE COATING WHICH CONTAINS COVALENTLY BONDED HEPARIN |
Publications (1)
Publication Number | Publication Date |
---|---|
JP2001500408A true JP2001500408A (ja) | 2001-01-16 |
Family
ID=24867595
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP10513888A Pending JP2001500408A (ja) | 1996-09-13 | 1997-09-11 | 共有結合ヘパリンを含む表面コーティングを介した有意な開通性強化を有するePTFE小直径血管移植片 |
Country Status (5)
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2005512778A (ja) * | 2001-12-12 | 2005-05-12 | カーディオバスク, インコーポレイテッド | 表面コーティング方法およびコーティングされたデバイス |
JP2007275598A (ja) * | 2006-04-06 | 2007-10-25 | Heraeus Kulzer Gmbh | 有効成分を有する血管グラフトの製造 |
JP2008500104A (ja) * | 2004-05-27 | 2008-01-10 | アドヴァンスド カーディオヴァスキュラー システムズ, インコーポレイテッド | ステント様インプラントにコートされたヘパリンを含有するブロックコポリマー |
Families Citing this family (87)
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FR2804328B1 (fr) | 2000-01-27 | 2002-03-15 | Hospal Ind | Membrane semi-permeable non thrombogene et procede de fabrication |
US6506437B1 (en) * | 2000-10-17 | 2003-01-14 | Advanced Cardiovascular Systems, Inc. | Methods of coating an implantable device having depots formed in a surface thereof |
US6544582B1 (en) * | 2001-01-05 | 2003-04-08 | Advanced Cardiovascular Systems, Inc. | Method and apparatus for coating an implantable device |
US6743462B1 (en) * | 2001-05-31 | 2004-06-01 | Advanced Cardiovascular Systems, Inc. | Apparatus and method for coating implantable devices |
US6695920B1 (en) | 2001-06-27 | 2004-02-24 | Advanced Cardiovascular Systems, Inc. | Mandrel for supporting a stent and a method of using the mandrel to coat a stent |
WO2003024186A2 (en) * | 2001-09-18 | 2003-03-27 | Eidgenossische Technische Hochschule Zurich | Methods and apparatus for patterning a surface |
EP1441865A4 (en) * | 2001-09-18 | 2010-04-07 | Eidgenoess Tech Hochschule | METHODS AND APPARATUS FOR ENRICHING SURFACES TO REDUCE PROTEIN ADSORPTION AND CELL ADHESION, AND FOR PRESENTING LIGANDS |
US20030077310A1 (en) | 2001-10-22 | 2003-04-24 | Chandrashekhar Pathak | Stent coatings containing HMG-CoA reductase inhibitors |
PL374315A1 (en) * | 2001-10-25 | 2005-10-03 | Wisconsin Alumni Research Foundation | Vascular stent or graft coated or impregnated with protein tyrosine kinase inhibitors and method of using same |
JP2005517490A (ja) * | 2001-12-21 | 2005-06-16 | カルディオバスク, インコーポレイテッド | ポリマー性カバリングおよび生体活性コーティングを有する複合ステント |
US20030161938A1 (en) * | 2002-02-22 | 2003-08-28 | Bo Johnson | Composition and method for coating medical devices |
KR100491700B1 (ko) * | 2002-03-22 | 2005-05-27 | 주식회사 뉴하트바이오 | 플라즈마 공정을 이용하여 ptfe 표면에 항혈전단백질을 고정화하는 방법 |
US7598224B2 (en) | 2002-08-20 | 2009-10-06 | Biosurface Engineering Technologies, Inc. | Dual chain synthetic heparin-binding growth factor analogs |
US7166574B2 (en) * | 2002-08-20 | 2007-01-23 | Biosurface Engineering Technologies, Inc. | Synthetic heparin-binding growth factor analogs |
US8227411B2 (en) | 2002-08-20 | 2012-07-24 | BioSurface Engineering Technologies, Incle | FGF growth factor analogs |
US20040116997A1 (en) | 2002-09-20 | 2004-06-17 | Taylor Charles S. | Stent-graft with positioning anchor |
US7468210B1 (en) | 2002-12-10 | 2008-12-23 | Biosurface Engineering Technologies, Inc. | Cross-linked heparin coatings and methods |
US7074276B1 (en) | 2002-12-12 | 2006-07-11 | Advanced Cardiovascular Systems, Inc. | Clamp mandrel fixture and a method of using the same to minimize coating defects |
WO2004075855A2 (en) | 2003-02-26 | 2004-09-10 | Biomed Solutions, Llc | Process for in vivo treatment of specific biological targets in bodily fluid |
DE10330900B4 (de) * | 2003-07-01 | 2006-09-14 | Leibniz-Institut Für Polymerforschung Dresden E.V. | Biomaterial mit einem modularen Beschichtungssystem zur Anwendung in Medizinprodukten mit direktem Blutkontakt |
US20050149176A1 (en) * | 2003-12-29 | 2005-07-07 | Scimed Life Systems, Inc. | Selectively light curable support members for medical devices |
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CA2555583A1 (en) | 2004-02-20 | 2005-09-09 | Biosurface Engineering Technologies, Inc. | Positive modulator of bone morphogenic protein-2 |
JP3790767B2 (ja) * | 2004-06-30 | 2006-06-28 | 森下仁丹株式会社 | 脂肪代謝改善組成物 |
US8048145B2 (en) | 2004-07-22 | 2011-11-01 | Endologix, Inc. | Graft systems having filling structures supported by scaffolds and methods for their use |
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US7597924B2 (en) | 2005-08-18 | 2009-10-06 | Boston Scientific Scimed, Inc. | Surface modification of ePTFE and implants using the same |
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US8388679B2 (en) | 2007-01-19 | 2013-03-05 | Maquet Cardiovascular Llc | Single continuous piece prosthetic tubular aortic conduit and method for manufacturing the same |
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1996
- 1996-09-13 US US08/713,800 patent/US6306165B1/en not_active Expired - Lifetime
-
1997
- 1997-09-11 JP JP10513888A patent/JP2001500408A/ja active Pending
- 1997-09-11 WO PCT/US1997/016163 patent/WO1998010806A1/en not_active Application Discontinuation
- 1997-09-11 EP EP97941549A patent/EP0929325A1/en not_active Withdrawn
- 1997-09-11 AU AU43436/97A patent/AU4343697A/en not_active Abandoned
-
2001
- 2001-06-20 US US09/885,361 patent/US6803069B2/en not_active Expired - Fee Related
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2005512778A (ja) * | 2001-12-12 | 2005-05-12 | カーディオバスク, インコーポレイテッド | 表面コーティング方法およびコーティングされたデバイス |
JP2008500104A (ja) * | 2004-05-27 | 2008-01-10 | アドヴァンスド カーディオヴァスキュラー システムズ, インコーポレイテッド | ステント様インプラントにコートされたヘパリンを含有するブロックコポリマー |
US9561309B2 (en) | 2004-05-27 | 2017-02-07 | Advanced Cardiovascular Systems, Inc. | Antifouling heparin coatings |
JP2007275598A (ja) * | 2006-04-06 | 2007-10-25 | Heraeus Kulzer Gmbh | 有効成分を有する血管グラフトの製造 |
Also Published As
Publication number | Publication date |
---|---|
AU4343697A (en) | 1998-04-02 |
US6306165B1 (en) | 2001-10-23 |
US6803069B2 (en) | 2004-10-12 |
EP0929325A1 (en) | 1999-07-21 |
US20010044655A1 (en) | 2001-11-22 |
WO1998010806A1 (en) | 1998-03-19 |
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