JP2001037857A - Solid composition including agaricus component having evaporation function, its manufacture and environment improving agent - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a solid composition including a useful agaricus component having the evaporation function, giving fine aromatic feeling and a disinfection effect. SOLUTION: This solid composition includes (A) an agaricus extracted component, (B) water or a mixture of water and a water soluble solvent capable of hydrogen bonding with water, (C) anion type high-molecular electrolyte expressed in the following formula (in the formula, X1-X4 are each H or CH3, Y1-Y4 are each H hydroxymethyl group or hydroxyethyl group, and 0<=a<=1, 0<=b<=1, and 0.1<=a+b<=1, 0<=c<=0.9, 0<=d<=0.9, and 0<=c+d<=0.9, a+b+c+d=1, 3000<=n<=300,000), and (D) a hydrophilic high molecular compound with caking function. And the quantity of the component (C) included in the composition is 0.00001-5 weight parts and the quantity of the component (D) included in the composition is 0.1-15 weight parts per 100 weight parts of the total quantity of the components (A) and (B).

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a solid composition containing an evaporative functional agaric component, a method for producing the same, and an environment improving agent. More specifically, the present invention provides an agaric component-containing solid composition having an evaporative function, giving a good odor sensation, showing a disinfecting property, and being useful as an environmental improving agent, and efficiently producing the same. And an environment-improving agent comprising the agaric component-containing solid composition.

[0002]

2. Description of the Related Art Basidiomycete-based Agaricus mushrooms containing β-glucan more than others have recently been used as a dietary supplement for antitumor activity, anticancer action, immune enhancement, anti-inflammatory action,
It has been studied to show a hypoglycemic action, a cholesterol-lowering action, an antiviral action, and the like, and agaricus mushrooms cultivated in various places have been dried to remove water and have been commercialized. Also, the high molecular polysaccharide β-glucan, which is a water-soluble substance contained in mushrooms, does not show any biological activity, so on pharmacology, we are paying attention to its selection. It has been determined that polysaccharides generally have the same antimicrobial properties. However, when trying to use agaricus mushrooms or an extracted component thereof as an industrial drug, there was concern about spoilage caused by being a natural food and an unpleasant odor caused by contaminants, and the like, and it was not realized.

[0003]

SUMMARY OF THE INVENTION Under such circumstances, the present invention provides a highly safe agaric component-containing solid composition having an evaporating function and giving a good odor sensation.
It is an object of the present invention to provide a method for efficiently producing the composition and an environment improving agent comprising the solid composition containing the agaric component.

[0004]

Means for Solving the Problems The present inventors have conducted intensive studies to achieve the above object, and have found that (A) an agaricus extract component, (B) water or a mixture of water and a specific water-soluble solvent. , (C) a specific anionic polymer electrolyte and (D)
A solid composition containing a solidified functional hydrophilic polymer compound at a predetermined ratio has a vaporizing function, and while giving a good odor sensation, shows a bactericidal property and is useful as an environment improving agent and the like. The solid composition containing an agaric extract component comprises (B) water or a mixture of water and a specific water-soluble solvent, (A) an agaric extract component, and (C) a specific anionic polymer electrolyte. (D) It has been found that a stable product can be efficiently produced by adding and mixing a solidifying functional hydrophilic polymer compound, and the present invention has been completed based on this finding.

That is, the present invention provides (A) an agaricus extract component, (B) water alone or a mixture of water and a water-soluble solvent capable of hydrogen bonding with water, and (C) a compound of the general formula (I).

Embedded image (However, X _{1 to} X ₄ are H, CH ₃ , Y _{1 to} Y ₄ are H, hydroxymethyl group or hydroxyethyl group, and 0 ≦
a ≦ 1, 0 ≦ b ≦ 1, and 0.1 ≦ a + b ≦ 1, 0 ≦
c ≦ 0.9, 0 ≦ d ≦ 0.9, and 0 ≦ c + d ≦ 0.
9, a + b + c + d = 1, 3000 ≦ n ≦ 300,000
It is. (C) per 100 parts by weight of the total amount of the components (A) and (B), which contains the anionic polymer electrolyte represented by the formula (1) and the solid polymerizable hydrophilic polymer (D). Wherein the content of the component (D) is from 0.00001 to 5 parts by weight and the content of the component (D) is from 0.1 to 15 parts by weight. It is intended to provide an environment improving agent comprising a component-containing solid composition.

According to the present invention, the above-mentioned solid composition containing an agaricus component having an evaporative function comprises (B) water alone or a mixture of water and a water-soluble solvent capable of hydrogen bonding with water, and (A) an agaricus extraction component. , (C) an anionic polymer electrolyte represented by the general formula I and (D) a solidifying functional hydrophilic polymer compound, and mixing.

[0007]

BEST MODE FOR CARRYING OUT THE INVENTION In the present invention, water is used alone or in combination with water and water in a pre-process of producing a solid composition containing an evaporative functional agaric component of the present invention using a raw material of Agaricus mushroom. The agaricus mushroom may be extracted from the component (B) comprising the mixture of the obtained water-soluble solvents to obtain the agaricus extracted component of the component (A), or separately from the agaricus mushroom by various methods. The agaricus extracted component of the component (A) obtained as described above may be dissolved in the component (B). In this case, the aqueous solution of a surfactant is allowed to act on Agaricus mushrooms, and the component (A) obtained by micellar catalyst extraction contains a water-insoluble component and a small amount of a surfactant. Absent. The raw material Agaricus mushrooms is not particularly limited and may be of any origin, for example, from Brazil, from China, from Japan, etc.
Either can be used.

In the present invention, water alone or a mixture of water and a water-soluble solvent capable of hydrogen bonding with water is used as the component (B). Here, examples of the water-soluble solvent capable of hydrogen bonding with water include methyl alcohol, ethyl alcohol, n-propyl alcohol, isopropyl alcohol, ethylene glycol, diethylene glycol, propylene glycol, dipropylene glycol, 1,3-
Butylene glycol, glycerin, ethylene glycol monomethyl ether, ethylene glycol monoethyl ether, ethylene glycol monopropyl ether, ethylene glycol monoisopropyl ether, ethylene glycol monobutyl ether, diethylene glycol monomethyl ether, diethylene glycol monoethyl ether, diethylene glycol monopropyl ether, diethylene glycol monoisopropyl ether,
Diethylene glycol monobutyl ether, propylene glycol monomethyl ether, propylene glycol monoethyl ether, propylene glycol monopropyl ether, propylene glycol monoisopropyl ether, propylene glycol monobutyl ether, dipropylene glycol monomethyl ether, dipropylene glycol monoethyl ether, dipropylene glycol monopropyl Ethers, alcohol solvents such as dipropylene glycol monoisopropyl ether and dipropylene glycol monobutyl ether, ethylene glycol dimethyl ether, ethylene glycol diethyl ether, diethylene glycol dimethyl ether, diethylene glycol diethyl ether, furfural,
Examples thereof include ether solvents such as dioxane, ketone solvents such as acetone and methyl ethyl ketone, and nitrogen-containing solvents such as 2-methylimidazolidinone. These water-soluble solvents may be used alone or as a mixture of two or more.

The anionic polyelectrolyte of the component (C) in the present invention may be prepared by homopolymerizing or copolymerizing sodium acrylate, potassium acrylate, sodium methacrylate and potassium methacrylate, or acrylamide, N-hydroxymethyl Acrylamide, N, N
-Di (hydroxymethyl) acrylamide, N-hydroxyethylacrylamide, N, N-di (hydroxyethyl) acrylamide, methacrylamide, N-hydroxymethylmethacrylamide, N, N-di (hydroxymethyl) methacrylamide, N-hydroxy Either partially or completely hydrolyzing a homopolymer or copolymer of ethyl methacrylamide and N, N-di (hydroxyethyl) methacrylamide with sodium hydroxide and / or potassium hydroxide, or one of the above nonionic monomers
These compounds are obtained by copolymerizing one or more of sodium or potassium acrylate, sodium methacrylate and potassium methacrylate with one or more of them, and representative examples thereof (hereinafter referred to as predetermined (Referred to as a polymer electrolyte), but is not limited thereto.

[0010]

Embedded image

[0011]

Embedded image

[0012]

Embedded image

Examples of the solidified functional hydrophilic polymer compound of the component (D) in the present invention include carrageenan, agar,
Guar gum, xanthan gum, cross-linked polyacrylic acid salts, cross-linked polyacrylamide, and the like. These may be used alone or in combination of two or more.

The solid composition containing the evaporative functional agaric component of the present invention comprises the above components (A), (B), (C) and (D), and comprises the component (C). The content of the anionic polymer electrolyte is 0.000 per 100 parts by weight of the total amount of the components (A) and (B).
It is selected in the range of 01 to 5 parts by weight. When the content of the component (C) is less than 0.0001 part by weight, it is difficult to stably maintain the component (A).
The vapor entrainment of the components is significantly inhibited. From the viewpoint of the balance between the stable retention of the component (A) and the entrainment of vaporization, the preferred content of the component (C) is 0.1% based on 100 parts by weight of the total amount of the components (A) and (B). 0001-0.
It is in the range of 5 parts by weight, particularly preferably in the range of 0.005 to 0.01 parts by weight.

On the other hand, the content of the solidified functional hydrophilic polymer compound of the component (D) is in the range of 0.1 to 15 parts by weight per 100 parts by weight of the total amount of the components (A) and (B). Is chosen. If the content of the component (D) is less than 0.1 part by weight, it is difficult to solidify the composition, and if it exceeds 15 parts by weight, the component (A) may be vaporized (B).
Significantly inhibits vaporization of components. Taking into account the solidification of the composition and the evaporative functionality of the active ingredient, the preferred content of the component (D) is 0.5 to 0.5 to 100 parts by weight of the total of the components (A) and (B). It is in the range of 10 parts by weight, particularly preferably in the range of 1 to 5 parts by weight.

The content ratio of component (A) to component (B) is preferably in the range of 1: 999 to 1: 9 by weight. If the amount of the component (A) is less than the above range, the amount of the active ingredient may be too small to achieve the object of the present invention, and if the amount is more than the above range, the stability retention of the component (A) tends to deteriorate. Can be A more preferable content ratio of the component (A) and the component (B) is in a range of 1: 499 to 1:19 by weight, and particularly preferably in a range of 1: 199 to 1:49.

Next, a method for producing the solid composition containing the evaporative functional agaric component of the present invention will be described. In the method of the present invention, the components (A) and (B) are mixed with the components (C) and (D), and specific embodiments thereof are as follows. First, the component (B) alone or a mixture of water and the above-mentioned water-soluble solvent is mixed and contacted with the raw material Agaricus mushroom, followed by filtration. The filtrate comprising the component (A) and the component (B) is filtered. Then, the anionic polymer electrolyte (C) and the solidified functional hydrophilic polymer electrolyte (D) are added and mixed, or they are separately extracted with water or alcohol. Components (C) and (D) are added to a solution obtained by dissolving the components extracted from Agaricus mushrooms in the component (B) by extraction, extraction with a mixed solvent of water-alcohol or micellar catalyst extraction using an aqueous surfactant solution. And mix.

Here, when the component (B) and the raw material Agaricus mushroom are mixed and brought into contact, the component (B) is preferably heated to 50 to 110 ° C, particularly preferably 80 to 100 ° C. At this time, it is preferable to perform a shaking or stirring operation, because the extraction efficiency of the agaricus component is further increased.

At the time of adding the component (C) to the solution composed of the components (A) and (B) and uniformly mixing the mixture, room temperature is sufficient. )) When the solidification is carried out by adding the components, preferably 0 to 1
When the liquid temperature is maintained at a temperature of 00 ° C, particularly preferably 50 to 70 ° C, solidification is performed more smoothly.

At this time, after leaving the solid composition in the manufacturing apparatus to form a solid composition, the solid composition may be discharged from the apparatus, or may be discharged from the apparatus in a liquid state, and then collected in a packaging container and allowed to stand. It may be a solid composition inside.

When the solid composition containing the evaporative functional agaric component of the present invention is brought into contact with a gaseous phase as it is, or when used in combination with a device such as a fan, the odor sensation in the surroundings is enhanced by the cooperative action of the components. It is also very useful as an environmental improver because it makes bacteria better and at the same time removes bacteria.

Various additives such as a coloring agent, a preservative, an antioxidant and a surfactant may be added to the solid composition containing the evaporative functional agaric component of the present invention, as long as the object of the present invention is not impaired. Can be added.

[0023]

Now, the present invention will be described in further detail with reference to Examples and Applications. However, the present invention is not limited to these Examples.

Example 1 95 parts by weight of water, 5 parts by weight of glycerin, and 10 parts by weight of Brazilian agaricus mushrooms were charged into a closed reactor equipped with a stirrer, a thermometer and a heating device.
The mixture was stirred and mixed at 0 ° C. for 3 hours. Thereafter, the stirring was stopped, and filtration was performed at 50 to 60 ° C. using No. 2 filter paper to obtain a filtrate containing 5% of an agaricus extract component.

Next, 0.01 part by weight of potassium polyacrylate having an average degree of polymerization of 100,000 was added to 100 parts by weight of the filtrate, and the mixture was stirred at 20 to 30 ° C. for 30 minutes to be uniformly dissolved. , Under heating, carrageenan [MR
C Polysaccharide Co., Ltd., trade name; Soagina WX
-560], and uniformly mixed at 65 ° C, and discharged from the reactor at 50 to 60 ° C. Then 2
The mixture was allowed to stand at 0 ° C. for 24 hours to obtain a light yellow evaporating functional agaric component-containing solid composition.

500 g of this composition was placed on top of 2.2
After filling a rectangular container with two holes of 2 cm, an air circulator with a built-in sirocco fan (32 cm x 1
Placed in a 6 cm × 18cm ones), placed cafeteria and break room of 90m ³ which are of five in 15 people smokers, 1 hour, creating a state in which the air circulation, the change of the disinfectant and odor sensory Observed the situation. Table 1 shows the results.

Comparative Example 1 95 parts by weight of water, 5 parts by weight of glycerin, 0.01 part by weight of potassium polyacrylate having an average degree of polymerization of 100,000 and the same as those used in Example 1 were placed in the same reactor as in Example 1. After 3.5 parts by weight of carrageenan was charged and uniformly mixed in the same manner as in Example 1, the mixture was allowed to stand at 20 ° C. for 24 hours to obtain a comparative solid composition containing no agaric extract component (A). . This composition was evaluated in the same manner as in Example 1. Table 1 shows the results.

Comparative Example 2 As in Example 1, 95 parts by weight of water, 5 parts by weight of glycerin, and 10 parts by weight of Brazilian agaricus mushroom were mixed and contacted, and the mixture contained 5% of an agaricus extract component obtained by filtration. With respect to 100 parts by weight of the filtrate, 3.5 parts by weight of the same carrageenan as used in Example 1 was charged and uniformly mixed in the same manner as in Example 1, and then allowed to stand at 20 ° C. for 24 hours. ) A comparative solid composition was obtained without the component potassium polyacrylate. This composition was evaluated in the same manner as in Example 1. Table 1 shows the results.

[0029]

[Table 1]

Note) * 1 Evaluating the disinfecting property, 1 m in front of the air was sampled by an air sampler and cultured on a standard agar medium at 25 ° C. for 7 days. I did. * 2 The odor sensation was evaluated according to the following criteria based on human odor. …: Odorless state, clean feeling is sufficiently recognized. …: There is no body odor or cigarette odor, but a slight smell of organic matter attached to the building is felt. Δ: Either or both of the body odor and the tobacco odor are weak. ×: Complex odors such as body odor, tobacco odor, and organic substance odor in the building are strongly felt. As is clear from Table 1, superior performance of the composition having an evaporative functional agaric component of Example 1 was confirmed as compared with Comparative Examples 1 and 2.

Example 2 An aqueous solution containing 3% of an agaricus extract component was placed in an open-type reactor equipped with a stirrer, a thermometer, and a heating and cooling device.
0 parts by weight and 0.02 parts by weight of sodium polyacrylate having an average degree of polymerization of 120,000 were charged at 20 to 30 ° C.
The mixture was stirred and mixed for minutes. Then, after lowering the internal temperature to 0 ° C., a crosslinked sodium polyacrylate [trade name: Biscomate PX-11, manufactured by Showa Denko KK] is stirred under stirring.
2] 3 parts by weight were added and uniformly mixed for 10 minutes to obtain a slightly yellow solid composition containing an evaporative functional agaric component. This composition was evaluated in the same manner as in Example 1. Table 2 shows the results.

COMPARATIVE EXAMPLE 3 100 parts by weight of water and 0.02% of sodium polyacrylate having an average degree of polymerization of 120,000 were placed in the same reactor as in Example 2.
After preparing a homogeneous solution by charging parts by weight, Example 2 was carried out at 0 ° C.
3 parts by weight of the same crosslinked sodium polyacrylate as used in 1) was added and mixed for 10 minutes to obtain a comparative solid composition containing no (A) agaricus extract component. This composition was evaluated in the same manner as in Example 2. Table 2 shows the results.

Comparative Example 4 In the same reactor as in Example 2, 3 components of the Agaricus extract component were added.
%, And the internal temperature was adjusted to 0 ° C., and then 3 parts by weight of the same cross-linked sodium polyacrylate as used in Example 2 was added. The mixture was mixed for 10 minutes to obtain a poly (C) component. A comparative solid composition without sodium acrylate was obtained. This composition was evaluated in the same manner as in Example 2. Table 2 shows the results.

[0034]

[Table 2]

Note) * 1 Evaluating the disinfection property, the air 1 m ahead was collected by an air sampler, cultured on a standard agar medium at 25 ° C. for 7 days, and the degree of decrease in the number of bacterial colonies was observed. I did. * 2 The odor sensation was evaluated according to the following criteria based on human odor. …: Odorless state, clean feeling is sufficiently recognized. …: There is no body odor or cigarette odor, but a slight smell of organic matter attached to the building is felt. Δ: Either or both of the body odor and the tobacco odor are weak. ×: Complex odors such as body odor, tobacco odor, and organic substance odor in the building are strongly felt. As is clear from Table 2, superior performance of the evaporative functional agaric component-containing composition of Example 2 was confirmed as compared with Comparative Examples 3 and 4.

Examples 3 to 8 The same as Example 1 or 2 except that the components (A), (B), (C) and (D) of the types and amounts shown in Tables 3 and 4 were used. Thus, a solid composition containing an evaporative functional agaric component was produced.

[0037]

[Table 3]

[0038]

[Table 4]

[Application Examples] Examples 1 to 8 and Comparative Examples 1 to 4
After filling each 100 g of the composition into a cylindrical container having a hole with a diameter of 2.2 cm, an air circulator with a built-in sirocco fan (8.5 cm × 9.
5cm x 24cm), average 10 days a day in the car
An average of 10 drivers a day spending ~ 20 cigarettes
Placed at the center of a passenger car [Corolla, manufactured by Toyota Motor Co., Ltd.]
Air circulation was performed for 24 hours.

Subsequently, the cylindrical container filled with each composition was taken out of the air circulating machine, and was fixed to the lower part of the outlet of the air conditioner device, and the heater and the cooler were alternately used for 5 minutes. During the hour, 120 men and women aged 20 to 60 who drive a car were randomly selected by a subject, and a panel test on breathing mood and odor sensation was conducted according to the following procedure. Carried out. Table 5 shows the results.

(1) Breathing mood Ten subjects were driven for one hour on a test car equipped with one type of composition and the breathing mood was compared with the state before the installation. . (2) Odor sensation Ten subjects were asked to drive one hour at a time on a test car equipped with one type of composition to smell the odor inside the car, and the difference in sensation between before and after installation was measured. I got an answer.

[0042]

[Table 5]

Note) * 1 The evaluation criteria for respiratory mood are as follows. …: All 10 testers were able to breathe more comfortably than before installation. …: 7 to 9 out of 10 testers can breathe more comfortably than before installation. Δ: 6 or less out of 10 testers who could breathe more comfortably than before installation. * The evaluation criteria for odor sensation are as follows. A: All 10 testers say that the smell inside the car, which has been used in the past, has disappeared and the car is in a fresh state. B: 1 to 3 testers out of 10 testers feel the same as before, and 9 to 7 testers are in a refreshing state. C: 4 to 6 out of 10 testers feel the same as before, and the other 6 to 4 say they are in a clean state. D: More than 7 people feel that they do not end in the past.

As is evident from Table 5, when the solid composition containing the evaporative functional agaric component of the present invention is attached, both the respiratory mood and the odor sensation are improved, and it is very excellent as an environment improving agent in a passenger car. You can see that there is.

[0045]

EFFECTS OF THE INVENTION The solid composition containing the evaporative functional agaricus component of the present invention is capable of uniformly dissolving the active ingredient extracted from the agaricus mushroom without causing precipitation in a state of contact with the aqueous solution of the polymer electrolyte. After that, it is solidified by the solidifying functional hydrophilic polymer compound, and becomes a stable solid in the composition. Thereby, the evaporating component and the accompanying component evaporate regularly and continuously, thereby removing bacteria. In addition, it gives a good odor sensation and is useful as an environmental improving agent. Therefore, by implementing the present invention, it becomes possible to apply the role of the agaricus extract component not only to the conventional use as a health food for drinking but also to a new life product to be installed in the environment.

 ──────────────────────────────────────────────────続 き Continued on the front page F term (reference) 4C080 AA03 BB02 BB05 CC02 CC12 HH05 JJ04 KK03 LL03 MM31 NN23 NN26 QQ03

Claims (8)

[Claims] 1. Agaric extract component, (B) water alone or a mixture of water and a water-soluble solvent capable of hydrogen bonding with water, (C) a general formula I (However, X _{1 to} X ₄ are H, CH ₃ , Y _{1 to} Y ₄ are H, hydroxymethyl group or hydroxyethyl group, and 0 ≦
a ≦ 1, 0 ≦ b ≦ 1, and 0.1 ≦ a + b ≦ 1, 0 ≦
c ≦ 0.9, 0 ≦ d ≦ 0.9, and 0 ≦ c + d ≦ 0.
9, a + b + c + d = 1, 3000 ≦ n ≦ 300,000
It is. (C) per 100 parts by weight of the total amount of the components (A) and (B), which contains the anionic polymer electrolyte represented by the formula (1) and the solid polymerizable hydrophilic polymer (D). Wherein the content of the component (D) is from 0.1 to 15 parts by weight, and the content of the component (D) is from 0.1 to 15 parts by weight. 2. The evaporative functional agaric component-containing solid composition according to claim 1, wherein the content ratio of the component (A) to the component (B) is 1: 999 to 1: 9 by weight. 3. The evaporative functional agaric component-containing solid composition according to claim 1, wherein the anionic polymer electrolyte as the component (C) is potassium or sodium polyacrylate. 4. The solid composition according to claim 1, wherein the solidified functional hydrophilic polymer compound (D) is carrageenan or a crosslinked sodium acrylate-acrylamide copolymer. 5. A method according to claim 1, wherein (B) water alone or a mixture of water and a water-soluble solvent capable of hydrogen bonding with water and (A) an agaricus extract component are represented by (C) a general formula (I). (However, X _{1 to} X ₄ are H, CH ₃ , Y _{1 to} Y ₄ are H, hydroxymethyl group or hydroxyethyl group, and 0 ≦
a ≦ 1, 0 ≦ b ≦ 1, and 0.1 ≦ a + b ≦ 1, 0 ≦
c ≦ 0.9, 0 ≦ d ≦ 0.9, and 0 ≦ c + d ≦ 0.
9, a + b + c + d = 1, 3000 ≦ n ≦ 300,000
It is. The evaporating function according to any one of claims 1 to 4, wherein the anionic polymer electrolyte represented by (1) and (D) a solidifying functional hydrophilic polymer compound are added and mixed. A method for producing a solid composition containing an agaricus component. 6. The production method according to claim 5, wherein the anionic polymer electrolyte of the component (C) is potassium or sodium polyacrylate. 7. The production method according to claim 5, wherein the solidified functional high molecular compound of the component (D) is carrageenan or a crosslinked sodium acrylate-acrylamide copolymer. 8. An environment-improving agent comprising the solid composition containing the evaporative functional agaric component according to any one of claims 1 to 4.