JP2000516585A5 - - Google Patents

Download PDF

Info

Publication number
JP2000516585A5
JP2000516585A5 JP1998508217A JP50821798A JP2000516585A5 JP 2000516585 A5 JP2000516585 A5 JP 2000516585A5 JP 1998508217 A JP1998508217 A JP 1998508217A JP 50821798 A JP50821798 A JP 50821798A JP 2000516585 A5 JP2000516585 A5 JP 2000516585A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP1998508217A
Other languages
English (en)
Japanese (ja)
Other versions
JP2000516585A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US1997/013882 external-priority patent/WO1998005323A2/en
Publication of JP2000516585A publication Critical patent/JP2000516585A/ja
Publication of JP2000516585A5 publication Critical patent/JP2000516585A5/ja
Pending legal-status Critical Current

Links

JP10508217A 1996-08-02 1997-08-01 血管新生阻害物質による雌生殖系の調節方法 Pending JP2000516585A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2338596P 1996-08-02 1996-08-02
US60/023,385 1996-08-02
PCT/US1997/013882 WO1998005323A2 (en) 1996-08-02 1997-08-01 Method of regulating the female reproductive system through angiogenesis inhibitors

Publications (2)

Publication Number Publication Date
JP2000516585A JP2000516585A (ja) 2000-12-12
JP2000516585A5 true JP2000516585A5 (enExample) 2005-04-07

Family

ID=21814780

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10508217A Pending JP2000516585A (ja) 1996-08-02 1997-08-01 血管新生阻害物質による雌生殖系の調節方法

Country Status (6)

Country Link
US (3) US6017949A (enExample)
EP (1) EP0957910A2 (enExample)
JP (1) JP2000516585A (enExample)
AU (2) AU3968597A (enExample)
CA (1) CA2262535A1 (enExample)
WO (2) WO1998005293A2 (enExample)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL183378B1 (pl) * 1995-03-27 2002-06-28 Assist Publ Hopitaux De Paris Zastosowanie fumagilolu i jego pochodnych do wytwarzania jelitowych środków przeciwinfekcyjnych
US6440445B1 (en) * 1996-09-30 2002-08-27 Brigham & Women's Hospital Methods and compounds for treatment of abnormal uterine bleeding
DE69824750T2 (de) * 1997-10-31 2005-07-07 Children's Medical Center Corp., Boston Methoden zur regulierung der grösse und des wachstums von durchblutetem normalem gewebe
CA2345276C (en) * 1998-10-09 2011-03-29 Ludwig Institute For Cancer Research Flt4 (vegfr-3) as a target for tumor imaging and anti-tumor therapy
US7141607B1 (en) * 2000-03-10 2006-11-28 Insite Vision Incorporated Methods and compositions for treating and inhibiting retinal neovascularization
JPWO2004022082A1 (ja) * 2002-09-04 2005-12-22 株式会社プロテイン・エクスプレス 胚着床制御剤
WO2004103159A2 (en) * 2003-05-14 2004-12-02 The Board Of Trustees Of The Leland Stanford Junior University Methods for modulating endometrium
EP1648575A4 (en) * 2003-07-14 2009-09-16 Fusion Sport Internat Pty Ltd METHOD, DEVICE AND SYSTEM FOR SPORT TRAINING AND TESTING
WO2005042566A2 (en) * 2003-08-29 2005-05-12 Children's Medical Center Corporation Antiangiogenicpeptides for treating or preventing endometriosis
US7524811B2 (en) * 2003-08-29 2009-04-28 Children's Medical Center Corporation Anti-angiogenic peptides from the N-terminus of endostatin
CN102099491A (zh) * 2008-05-15 2011-06-15 北卡罗来纳-查佩尔山大学 调节血管生成的新靶标
EP2140860A1 (en) * 2008-07-03 2010-01-06 Bayer Schering Pharma Oy An improved method of contraception
NZ590732A (en) * 2008-07-18 2012-09-28 Zafgen Inc Methods of treating an overweight or obese subject using fumagillin
US20100159506A1 (en) * 2008-07-25 2010-06-24 Cellscape Corporation Methods and systems for genetic analysis of fetal nucleated red blood cells
WO2010065883A2 (en) 2008-12-04 2010-06-10 Zafgen Corporation Method of treating an overweight or obese subject
WO2010065877A2 (en) 2008-12-04 2010-06-10 Zafgen Corporation Methods of treating an overweight or obese subject
CN102639494B (zh) 2009-10-09 2016-11-09 扎夫根公司 砜化合物及其制备和使用方法
WO2011085198A1 (en) 2010-01-08 2011-07-14 Zafgen Corporation Metap-2 inhibitor for use in treating benign prostatic hypertrophy (bph)
CA2786603C (en) 2010-01-08 2018-02-20 James E. Vath Fumagillol type compounds and methods of making and using same
RU2427325C1 (ru) * 2010-01-29 2011-08-27 Государственное образовательное учреждение высшего профессионального образования "Астраханская государственная медицинская академия Федерального агентства по здравоохранению и социальному развитию" (ГОУ ВПО АГМА Росздрава) Способ оценки эффективности лечения хронической плацентарной недостаточности в эксперименте
US8774488B2 (en) 2010-03-11 2014-07-08 Cellscape Corporation Method and device for identification of nucleated red blood cells from a maternal blood sample
US20130266578A1 (en) 2010-04-07 2013-10-10 Thomas E. Hughes Methods of treating an overweight subject
CN103079567A (zh) 2010-04-17 2013-05-01 拜尔健康护理有限责任公司 用于疾病和病症的治疗和预防的氟取代的ω-羧基芳基二苯脲的合成代谢产物
EP2595628A1 (en) 2010-07-19 2013-05-29 Bayer HealthCare LLC Drug combinations with fluoro-substituted omega-carboxyaryl diphenyl urea for the treatment and prevention of diseases and conditions
CN103249735B (zh) 2010-07-22 2016-04-06 扎夫根股份有限公司 三环化合物及其制备和使用方法
PH12013500934A1 (en) 2010-11-09 2022-10-24 Zafgen Inc Crystalline solids of a metap-2 inhibitor and methods of making and using same
BR112013013411A2 (pt) 2010-11-29 2016-09-13 Zafgen Inc tratamento de obesidade usando administração não diária de 6-0-(4-dimetilaminoetxi) cinamoil fumagilol
CN103402989B (zh) 2011-01-26 2016-04-06 扎夫根股份有限公司 四唑化合物及其制备和使用方法
JP5876513B2 (ja) 2011-03-08 2016-03-02 ザフゲン,インコーポレイテッド オキサスピロ[2.5]オクタン誘導体および類似体
CA2835195A1 (en) 2011-05-06 2012-11-15 Zafgen, Inc. Tricyclic sulfonamide compounds and methods of making and using same
US9290472B2 (en) 2011-05-06 2016-03-22 Zafgen, Inc. Partially saturated tricyclic compounds and methods of making and using same
MX343688B (es) 2011-05-06 2016-11-16 Zafgen Inc Compuestos tricíclicos de sulfonamida y pirazolo y métodos para su fabricación y uso.
EP2763671A2 (en) 2011-10-03 2014-08-13 Zafgen, Inc. Methods of treating age related disorders
CA2861390A1 (en) 2012-01-18 2013-07-25 Zafgen, Inc. Tricyclic sulfonamide compounds and methods of making and using same
WO2013109735A1 (en) 2012-01-18 2013-07-25 Zafgen, Inc. Tricyclic sulfone compounds and methods of making and using same
BR112014027808A2 (pt) 2012-05-07 2017-06-27 Zafgen Inc sal polimórfico do sal de oxalato de 6-o-(4-dimetilaminoetoxi) cinaroil fumagilol e métodos de produção e utilização do mesmo
CN104363905A (zh) 2012-05-08 2015-02-18 扎夫根股份有限公司 用metap2抑制剂治疗下丘脑性肥胖
KR20150016534A (ko) 2012-05-09 2015-02-12 자프겐 인크. 푸마지롤형 화합물 및 이의 제조 및 사용 방법
CA2890342A1 (en) 2012-11-05 2014-05-08 Zafgen, Inc. Tricyclic compounds and methods of making and using same
SG11201503521QA (en) 2012-11-05 2015-06-29 Zafgen Inc Methods of treating liver diseases
AU2013337288A1 (en) 2012-11-05 2015-05-21 Zafgen, Inc. Tricyclic compounds for use in the treatment and/or control of obesity
MX362391B (es) 2013-03-14 2019-01-15 Zafgen Inc Métodos de tratamiento de enfermedad renal y otros trastornos.
CN106432255A (zh) 2015-08-11 2017-02-22 扎夫根公司 烟曲霉素醇螺环化合物和制备和使用其的方法
AR105671A1 (es) 2015-08-11 2017-10-25 Zafgen Inc Compuestos heterocíclicos de fumagillol y sus métodos de elaboración y uso

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK168876B1 (da) * 1982-12-20 1994-07-04 Harvard College Middel, der kan administreres oralt eller subcutant, til inhibering af angiogenese hos pattedyr samt fremgangsmåde til fremstilling af et sådant middel
DE3344797A1 (de) * 1983-12-10 1985-06-20 Th. Kieserling & Albrecht Gmbh & Co, 5650 Solingen Transportvorrichtung fuer felgenrohlinge
US4599331A (en) * 1984-12-24 1986-07-08 Syntex (U.S.A.) Inc. Etianic acids as antiangiogenics
DE68915900T2 (de) * 1988-09-01 1994-11-24 Childrens Medical Center Angiogenese hemmendes Mittel.
US5086164A (en) * 1989-01-10 1992-02-04 Repligen Corporation Novel methods and compositions for treatment of angiogenic diseases
JPH05507912A (ja) * 1990-06-11 1993-11-11 アルコン・ラボラトリーズ,インコーポレイテッド 血管形成を阻害するステロイド
FR2672801B1 (fr) * 1991-02-14 1995-03-03 Sanofi Sa Utilisation de derives de tetrahydrothienopyridine comme inhibiteurs de l'angiogenese.
GB9225475D0 (en) * 1992-12-05 1993-01-27 Imp Cancer Res Tech Compounds to combat angiogenesis
JPH08509703A (ja) * 1993-03-12 1996-10-15 ゾーマ コーポレイション 殺菌/透過性増加タンパク質産物の治療用途
DE69417169T2 (de) * 1993-09-24 1999-07-22 Takeda Chemical Industries, Ltd., Osaka Antineoplastische pharmazeutische Zusammensetzung enthaltend ein Fumagillolderivat und einen Platinkomplex
GB9410533D0 (en) 1994-05-26 1994-07-13 Lynxvale Ltd In situ hybridisation and immuno-Chemical localisation of a growth factor
GB9410534D0 (en) * 1994-05-26 1994-07-13 Lynxvale Ltd Improvements in or relating to growth factor inhibitors
CN1202932A (zh) * 1995-10-23 1998-12-23 儿童医学中心公司 治疗用抗血管生成的组合物和方法

Similar Documents

Publication Publication Date Title
JP2000516370A5 (enExample)
JP2001506156A5 (enExample)
JP2001527708A5 (enExample)
JP2000515479A5 (enExample)
JP2000513248A5 (enExample)
JP2000513608A5 (enExample)
JP2000508206A5 (enExample)
JP2001501409A5 (enExample)
JP2000513097A5 (enExample)
JP2001503806A5 (enExample)
JP2000510280A5 (enExample)
JP2001500952A5 (enExample)
JP2001505643A5 (enExample)
JP2000511416A5 (enExample)
JP2001507106A5 (enExample)
JP2000512107A5 (enExample)
JP2001503227A5 (enExample)
JP2001506297A5 (enExample)
JP2001504437A5 (enExample)
JP2000515995A5 (enExample)
JP2000516585A5 (enExample)
JP2001502461A5 (enExample)
JP2000516933A5 (enExample)
JP2001501351A5 (enExample)
JP2001504129A5 (enExample)