JP2000515778A - 体液成分レベルの生体内測定および制御のための埋込可能センサーおよびシステム - Google Patents
体液成分レベルの生体内測定および制御のための埋込可能センサーおよびシステムInfo
- Publication number
- JP2000515778A JP2000515778A JP10505318A JP50531898A JP2000515778A JP 2000515778 A JP2000515778 A JP 2000515778A JP 10505318 A JP10505318 A JP 10505318A JP 50531898 A JP50531898 A JP 50531898A JP 2000515778 A JP2000515778 A JP 2000515778A
- Authority
- JP
- Japan
- Prior art keywords
- light
- sensor
- light source
- body fluid
- detector
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
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- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
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| PCT/US1996/011435 WO1997001986A1 (en) | 1995-07-06 | 1996-07-08 | Implantable sensor and system for measurement and control of blood constituent levels |
| PCT/US1997/011832 WO1998001071A1 (en) | 1996-07-08 | 1997-07-08 | Implantable sensor and system for in vivo measurement and control of fluid constituent levels |
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| US (1) | US6049727A (cg-RX-API-DMAC7.html) |
| EP (1) | EP0923335B1 (cg-RX-API-DMAC7.html) |
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| CA (1) | CA2259254C (cg-RX-API-DMAC7.html) |
| IL (1) | IL127213A (cg-RX-API-DMAC7.html) |
| WO (1) | WO1998001071A1 (cg-RX-API-DMAC7.html) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004358244A (ja) * | 2003-05-30 | 2004-12-24 | Siemens Ag | 生物の代謝過程における少なくとも１つの物質の検出方法および装置 |
| JP2005525139A (ja) * | 2001-10-23 | 2005-08-25 | メドトロニック ミニメド インコーポレイテッド | 非血管センサ埋め込みのための方法およびシステム |
| JP2006500170A (ja) * | 2002-09-27 | 2006-01-05 | メドトロニック ミニメド インコーポレイテッド | 埋込可能型センサ方法及びシステム |
| JP2008191149A (ja) * | 2007-02-05 | 2008-08-21 | Palo Alto Research Center Inc | 植設用光学キャビティ構造 |
| US8465466B2 (en) | 2001-10-23 | 2013-06-18 | Medtronic Minimed, Inc | Method and system for non-vascular sensor implantation |
| US8506550B2 (en) | 2001-09-07 | 2013-08-13 | Medtronic Minimed, Inc. | Method and system for non-vascular sensor implantation |
| JP2013533769A (ja) * | 2010-06-22 | 2013-08-29 | センスペック・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 測定媒体の成分または特性、特に生理的血液値を特定およびモニタするための装置ならびに方法 |
Families Citing this family (553)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6240306B1 (en) | 1995-08-09 | 2001-05-29 | Rio Grande Medical Technologies, Inc. | Method and apparatus for non-invasive blood analyte measurement with fluid compartment equilibration |
| US8527026B2 (en) | 1997-03-04 | 2013-09-03 | Dexcom, Inc. | Device and method for determining analyte levels |
| US7192450B2 (en) | 2003-05-21 | 2007-03-20 | Dexcom, Inc. | Porous membranes for use with implantable devices |
| US6001067A (en) | 1997-03-04 | 1999-12-14 | Shults; Mark C. | Device and method for determining analyte levels |
| US6862465B2 (en) | 1997-03-04 | 2005-03-01 | Dexcom, Inc. | Device and method for determining analyte levels |
| US20050033132A1 (en) | 1997-03-04 | 2005-02-10 | Shults Mark C. | Analyte measuring device |
| US7657297B2 (en) | 2004-05-03 | 2010-02-02 | Dexcom, Inc. | Implantable analyte sensor |
| US7267665B2 (en) * | 1999-06-03 | 2007-09-11 | Medtronic Minimed, Inc. | Closed loop system for controlling insulin infusion |
| US5954643A (en) * | 1997-06-09 | 1999-09-21 | Minimid Inc. | Insertion set for a transcutaneous sensor |
| US7890158B2 (en) * | 2001-06-05 | 2011-02-15 | Lumidigm, Inc. | Apparatus and method of biometric determination using specialized optical spectroscopy systems |
| US6628809B1 (en) | 1999-10-08 | 2003-09-30 | Lumidigm, Inc. | Apparatus and method for identification of individuals by near-infrared spectrum |
| US6558351B1 (en) | 1999-06-03 | 2003-05-06 | Medtronic Minimed, Inc. | Closed loop system for controlling insulin infusion |
| US7039446B2 (en) * | 2001-01-26 | 2006-05-02 | Sensys Medical, Inc. | Indirect measurement of tissue analytes through tissue properties |
| GB2333152B (en) * | 1998-01-08 | 2002-11-06 | Diametrics Medical Ltd | Method and apparatus for monitoring cerebral physiology |
| DE19801616A1 (de) * | 1998-01-17 | 1999-07-29 | Sl Elektronik Mechanik Gmbh | Vorrichtung zur Bestimmung und/oder Anzeige und/oder Ausgabe wenigstens eines, wenigstens eine Körperfunktion charakterisierenden Werts |
| DE19811017A1 (de) * | 1998-03-13 | 1999-09-16 | Dade Behring Marburg Gmbh | Neues Verfahren zur Bestimmung von Plasmaproteinen und Faktoren der Hämostase sowie ein neues, implantierbares Meßgerät |
| US6560478B1 (en) * | 1998-03-16 | 2003-05-06 | The Research Foundation Of City University Of New York | Method and system for examining biological materials using low power CW excitation Raman spectroscopy |
| US7899518B2 (en) | 1998-04-06 | 2011-03-01 | Masimo Laboratories, Inc. | Non-invasive tissue glucose level monitoring |
| US6728560B2 (en) | 1998-04-06 | 2004-04-27 | The General Hospital Corporation | Non-invasive tissue glucose level monitoring |
| US20020091324A1 (en) * | 1998-04-06 | 2002-07-11 | Nikiforos Kollias | Non-invasive tissue glucose level monitoring |
| US8480580B2 (en) | 1998-04-30 | 2013-07-09 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US9066695B2 (en) | 1998-04-30 | 2015-06-30 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US8465425B2 (en) | 1998-04-30 | 2013-06-18 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US6949816B2 (en) | 2003-04-21 | 2005-09-27 | Motorola, Inc. | Semiconductor component having first surface area for electrically coupling to a semiconductor chip and second surface area for electrically coupling to a substrate, and method of manufacturing same |
| US8688188B2 (en) | 1998-04-30 | 2014-04-01 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US8974386B2 (en) | 1998-04-30 | 2015-03-10 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US8346337B2 (en) | 1998-04-30 | 2013-01-01 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US6175752B1 (en) | 1998-04-30 | 2001-01-16 | Therasense, Inc. | Analyte monitoring device and methods of use |
| DE69914319T2 (de) * | 1998-05-13 | 2004-11-18 | Cygnus, Inc., Redwood City | Signalverarbeitung zur messung von physiologischen analyten |
| ATE468068T1 (de) * | 1998-07-04 | 2010-06-15 | Whitland Res Ltd | Unblutige messung von analyten aus blut |
| JP4469504B2 (ja) * | 1998-10-08 | 2010-05-26 | メドトロニック ミニメド インコーポレイテッド | 遠隔形質モニタシステム |
| US6227114B1 (en) * | 1998-12-29 | 2001-05-08 | Cidra Corporation | Select trigger and detonation system using an optical fiber |
| US7436511B2 (en) * | 1999-01-22 | 2008-10-14 | Sensys Medical, Inc. | Analyte filter method and apparatus |
| WO2000047109A1 (en) * | 1999-02-12 | 2000-08-17 | Cygnus, Inc. | Devices and methods for frequent measurement of an analyte present in a biological system |
| US6424847B1 (en) * | 1999-02-25 | 2002-07-23 | Medtronic Minimed, Inc. | Glucose monitor calibration methods |
| US7047054B2 (en) * | 1999-03-12 | 2006-05-16 | Cas Medical Systems, Inc. | Laser diode optical transducer assembly for non-invasive spectrophotometric blood oxygenation monitoring |
| US6669663B1 (en) * | 1999-04-30 | 2003-12-30 | Medtronic, Inc. | Closed loop medicament pump |
| US6216022B1 (en) * | 2000-06-22 | 2001-04-10 | Biosafe Laboratories, Inc. | Implantable optical measurement device and method for using same |
| AU7754600A (en) * | 1999-10-08 | 2001-04-23 | Biosafe Laboratories, Inc. | Implantable optical measurement device and method |
| US6816605B2 (en) | 1999-10-08 | 2004-11-09 | Lumidigm, Inc. | Methods and systems for biometric identification of individuals using linear optical spectroscopy |
| US6438397B1 (en) * | 1999-10-28 | 2002-08-20 | Gerald G. Bosquet | Method and apparatus for analyte detection using intradermally implanted skin port |
| US6748334B1 (en) * | 1999-12-06 | 2004-06-08 | Jorge E. Perez | Specialty gas analysis system |
| US6594513B1 (en) * | 2000-01-12 | 2003-07-15 | Paul D. Jobsis | Method and apparatus for determining oxygen saturation of blood in body organs |
| US6383767B1 (en) * | 2000-01-21 | 2002-05-07 | Motorola, Inc. | Luminescent in vivo glucose measurement |
| WO2001060247A1 (en) | 2000-02-18 | 2001-08-23 | Argose, Inc. | Generation of spatially-averaged excitation-emission map in heterogeneous tissue |
| US7890295B2 (en) | 2000-02-23 | 2011-02-15 | Medtronic Minimed, Inc. | Real time self-adjusting calibration algorithm |
| DE10011284B4 (de) * | 2000-03-08 | 2007-06-28 | Disetronic Licensing Ag | Vorrichtung für eine In-vivo Messung der Konzentration eines Inhaltsstoffs einer Körperflüssigkeit |
| US7509153B2 (en) * | 2000-09-26 | 2009-03-24 | Sensys Medical, Inc. | Method and apparatus for control of skin perfusion for indirect glucose measurement |
| US7553280B2 (en) * | 2000-06-29 | 2009-06-30 | Sensors For Medicine And Science, Inc. | Implanted sensor processing system and method |
| US6757558B2 (en) * | 2000-07-06 | 2004-06-29 | Algodyne, Ltd. | Objective pain measurement system and method |
| US6740059B2 (en) | 2000-09-08 | 2004-05-25 | Insulet Corporation | Devices, systems and methods for patient infusion |
| DE10048375A1 (de) * | 2000-09-29 | 2002-05-08 | Michele Delsanter | Multifunktionale und multiparametrische Biochip-Anordnung |
| DE10049900C1 (de) * | 2000-10-10 | 2001-10-25 | Fresenius Medical Care De Gmbh | Verfahren zur Bestimmung des Intraperitonealvolumens und Vorrichtung zur Peritonealdialyse |
| US6560471B1 (en) | 2001-01-02 | 2003-05-06 | Therasense, Inc. | Analyte monitoring device and methods of use |
| US6952603B2 (en) | 2001-03-16 | 2005-10-04 | Roche Diagnostics Operations, Inc. | Subcutaneous analyte sensor |
| US7041468B2 (en) | 2001-04-02 | 2006-05-09 | Therasense, Inc. | Blood glucose tracking apparatus and methods |
| US7043288B2 (en) * | 2002-04-04 | 2006-05-09 | Inlight Solutions, Inc. | Apparatus and method for spectroscopic analysis of tissue to detect diabetes in an individual |
| US6983176B2 (en) | 2001-04-11 | 2006-01-03 | Rio Grande Medical Technologies, Inc. | Optically similar reference samples and related methods for multivariate calibration models used in optical spectroscopy |
| US6865408B1 (en) | 2001-04-11 | 2005-03-08 | Inlight Solutions, Inc. | System for non-invasive measurement of glucose in humans |
| US7521019B2 (en) * | 2001-04-11 | 2009-04-21 | Lifescan, Inc. | Sensor device and methods for manufacture |
| US6862091B2 (en) | 2001-04-11 | 2005-03-01 | Inlight Solutions, Inc. | Illumination device and method for spectroscopic analysis |
| US6574490B2 (en) | 2001-04-11 | 2003-06-03 | Rio Grande Medical Technologies, Inc. | System for non-invasive measurement of glucose in humans |
| US6694158B2 (en) | 2001-04-11 | 2004-02-17 | Motorola, Inc. | System using a portable detection device for detection of an analyte through body tissue |
| US7126682B2 (en) | 2001-04-11 | 2006-10-24 | Rio Grande Medical Technologies, Inc. | Encoded variable filter spectrometer |
| US6748250B1 (en) * | 2001-04-27 | 2004-06-08 | Medoptix, Inc. | Method and system of monitoring a patient |
| US20090137888A9 (en) * | 2001-04-27 | 2009-05-28 | Berman Herbert L | System for monitoring of patients |
| US20040267100A1 (en) * | 2001-05-18 | 2004-12-30 | Mark Faupel | System and method for monitoring or treating a health condition |
| US20030208113A1 (en) * | 2001-07-18 | 2003-11-06 | Mault James R | Closed loop glycemic index system |
| US20030032874A1 (en) | 2001-07-27 | 2003-02-13 | Dexcom, Inc. | Sensor head for use with implantable devices |
| US6702857B2 (en) | 2001-07-27 | 2004-03-09 | Dexcom, Inc. | Membrane for use with implantable devices |
| US6544212B2 (en) | 2001-07-31 | 2003-04-08 | Roche Diagnostics Corporation | Diabetes management system |
| WO2003016882A1 (en) * | 2001-08-14 | 2003-02-27 | Purdue Research Foundation | Measuring a substance in a biological sample |
| US20040147034A1 (en) * | 2001-08-14 | 2004-07-29 | Gore Jay Prabhakar | Method and apparatus for measuring a substance in a biological sample |
| US6671554B2 (en) | 2001-09-07 | 2003-12-30 | Medtronic Minimed, Inc. | Electronic lead for a medical implant device, method of making same, and method and apparatus for inserting same |
| US6915147B2 (en) | 2001-09-07 | 2005-07-05 | Medtronic Minimed, Inc. | Sensing apparatus and process |
| US7323142B2 (en) * | 2001-09-07 | 2008-01-29 | Medtronic Minimed, Inc. | Sensor substrate and method of fabricating same |
| US8152789B2 (en) * | 2001-10-23 | 2012-04-10 | Medtronic Minimed, Inc. | System and method for providing closed loop infusion formulation delivery |
| US6827702B2 (en) | 2001-09-07 | 2004-12-07 | Medtronic Minimed, Inc. | Safety limits for closed-loop infusion pump control |
| US7025760B2 (en) * | 2001-09-07 | 2006-04-11 | Medtronic Minimed, Inc. | Method and system for non-vascular sensor implantation |
| US20050267326A1 (en) * | 2001-10-02 | 2005-12-01 | Alfred E. Mann Institute For Biomedical Eng. At The University Of Southern California | Percutaneous chemical sensor based on fluorescence resonant energy transfer (FRET) |
| US6809507B2 (en) * | 2001-10-23 | 2004-10-26 | Medtronic Minimed, Inc. | Implantable sensor electrodes and electronic circuitry |
| US7192766B2 (en) * | 2001-10-23 | 2007-03-20 | Medtronic Minimed, Inc. | Sensor containing molded solidified protein |
| US6989891B2 (en) * | 2001-11-08 | 2006-01-24 | Optiscan Biomedical Corporation | Device and method for in vitro determination of analyte concentrations within body fluids |
| US20040137547A1 (en) * | 2001-12-28 | 2004-07-15 | Medtronic Minimed, Inc. | Method for formulating a glucose oxidase enzyme with a desired property or properties and a glucose oxidase enzyme with the desired property |
| US20040073175A1 (en) * | 2002-01-07 | 2004-04-15 | Jacobson James D. | Infusion system |
| US8010174B2 (en) * | 2003-08-22 | 2011-08-30 | Dexcom, Inc. | Systems and methods for replacing signal artifacts in a glucose sensor data stream |
| US9282925B2 (en) | 2002-02-12 | 2016-03-15 | Dexcom, Inc. | Systems and methods for replacing signal artifacts in a glucose sensor data stream |
| US8260393B2 (en) | 2003-07-25 | 2012-09-04 | Dexcom, Inc. | Systems and methods for replacing signal data artifacts in a glucose sensor data stream |
| US9247901B2 (en) | 2003-08-22 | 2016-02-02 | Dexcom, Inc. | Systems and methods for replacing signal artifacts in a glucose sensor data stream |
| WO2003071939A1 (en) * | 2002-02-22 | 2003-09-04 | Masimo Corporation | Active pulse spectraphotometry |
| DE10212140A1 (de) * | 2002-03-19 | 2003-10-09 | Henry Arthur Muglia | Blutzuckersensor und Meßverfahren zur Bestimmung des Blutzuckerwerts |
| US7027848B2 (en) | 2002-04-04 | 2006-04-11 | Inlight Solutions, Inc. | Apparatus and method for non-invasive spectroscopic measurement of analytes in tissue using a matched reference analyte |
| US6960192B1 (en) | 2002-04-23 | 2005-11-01 | Insulet Corporation | Transcutaneous fluid delivery system |
| US7226978B2 (en) | 2002-05-22 | 2007-06-05 | Dexcom, Inc. | Techniques to improve polyurethane membranes for implantable glucose sensors |
| US20060258761A1 (en) * | 2002-05-22 | 2006-11-16 | Robert Boock | Silicone based membranes for use in implantable glucose sensors |
| GB2418258B (en) * | 2002-06-05 | 2006-08-23 | Diabetes Diagnostics Inc | Analyte testing device |
| FR2842108B1 (fr) * | 2002-07-09 | 2008-05-02 | Effik | Composes a base d'hormone et de monoxyde d'azote et leur utilisation en obstetrique et en gynecologie |
| US7288768B2 (en) * | 2002-07-18 | 2007-10-30 | Purdue Research Foundation | Method for measuring the amount of an organic substance in a food product with infrared electromagnetic radiation |
| US7689268B2 (en) * | 2002-08-05 | 2010-03-30 | Infraredx, Inc. | Spectroscopic unwanted signal filters for discrimination of vulnerable plaque and method therefor |
| US7620212B1 (en) | 2002-08-13 | 2009-11-17 | Lumidigm, Inc. | Electro-optical sensor |
| US7508608B2 (en) * | 2004-11-17 | 2009-03-24 | Illumina, Inc. | Lithographically fabricated holographic optical identification element |
| AU2003265584C1 (en) * | 2002-08-20 | 2009-05-21 | Cyvera Corporation | Diffraction grating-based encoded micro-particles for multiplexed experiments |
| US7126755B2 (en) * | 2002-09-12 | 2006-10-24 | Moon John A | Method and apparatus for labeling using diffraction grating-based encoded optical identification elements |
| US7872804B2 (en) | 2002-08-20 | 2011-01-18 | Illumina, Inc. | Encoded particle having a grating with variations in the refractive index |
| US7349158B2 (en) * | 2002-09-12 | 2008-03-25 | Cyvera Corporation | Diffraction grating-based encoded micro-particles for multiplexed experiments |
| US7164533B2 (en) * | 2003-01-22 | 2007-01-16 | Cyvera Corporation | Hybrid random bead/chip based microarray |
| US20050227252A1 (en) * | 2002-08-20 | 2005-10-13 | Moon John A | Diffraction grating-based encoded articles for multiplexed experiments |
| US7900836B2 (en) | 2002-08-20 | 2011-03-08 | Illumina, Inc. | Optical reader system for substrates having an optically readable code |
| AU2003265583C1 (en) * | 2002-08-20 | 2009-05-21 | Cyvera Corporation | Diffraction grating-based optical identification element |
| US7441703B2 (en) * | 2002-08-20 | 2008-10-28 | Illumina, Inc. | Optical reader for diffraction grating-based encoded optical identification elements |
| US7901630B2 (en) | 2002-08-20 | 2011-03-08 | Illumina, Inc. | Diffraction grating-based encoded microparticle assay stick |
| US7619819B2 (en) | 2002-08-20 | 2009-11-17 | Illumina, Inc. | Method and apparatus for drug product tracking using encoded optical identification elements |
| US7923260B2 (en) | 2002-08-20 | 2011-04-12 | Illumina, Inc. | Method of reading encoded particles |
| WO2004025561A1 (en) * | 2002-09-12 | 2004-03-25 | Cyvera Corporation | Chemical synthesis using diffraction grating-based encoded optical elements |
| US7092160B2 (en) | 2002-09-12 | 2006-08-15 | Illumina, Inc. | Method of manufacturing of diffraction grating-based optical identification element |
| EP1540590A1 (en) * | 2002-09-12 | 2005-06-15 | Cyvera Corporation | Assay stick comprising coded microbeads |
| WO2004024328A1 (en) * | 2002-09-12 | 2004-03-25 | Cyvera Corporation | Method and apparatus for aligning elongated microbeads in order to interrogate the same |
| US20100255603A9 (en) | 2002-09-12 | 2010-10-07 | Putnam Martin A | Method and apparatus for aligning microbeads in order to interrogate the same |
| US7144384B2 (en) | 2002-09-30 | 2006-12-05 | Insulet Corporation | Dispenser components and methods for patient infusion device |
| US7128727B2 (en) | 2002-09-30 | 2006-10-31 | Flaherty J Christopher | Components and methods for patient infusion device |
| US7381184B2 (en) | 2002-11-05 | 2008-06-03 | Abbott Diabetes Care Inc. | Sensor inserter assembly |
| DE10256188A1 (de) * | 2002-12-02 | 2004-06-24 | Johann Wolfgang Goethe-Universität Frankfurt am Main | Reflexionsspektrometer |
| US7174198B2 (en) * | 2002-12-27 | 2007-02-06 | Igor Trofimov | Non-invasive detection of analytes in a complex matrix |
| AU2003303597A1 (en) | 2002-12-31 | 2004-07-29 | Therasense, Inc. | Continuous glucose monitoring system and methods of use |
| US8081792B2 (en) | 2003-08-20 | 2011-12-20 | Illumina, Inc. | Fourier scattering methods for encoding microbeads and methods and apparatus for reading the same |
| DE602004003414T2 (de) | 2003-04-03 | 2007-09-27 | Matsushita Electric Industrial Co., Ltd., Kadoma | Methode und Gerät zur Konzentrationmessung einer spezifischen Komponente |
| US7539330B2 (en) * | 2004-06-01 | 2009-05-26 | Lumidigm, Inc. | Multispectral liveness determination |
| US7460696B2 (en) | 2004-06-01 | 2008-12-02 | Lumidigm, Inc. | Multispectral imaging biometrics |
| US7394919B2 (en) | 2004-06-01 | 2008-07-01 | Lumidigm, Inc. | Multispectral biometric imaging |
| US7347365B2 (en) * | 2003-04-04 | 2008-03-25 | Lumidigm, Inc. | Combined total-internal-reflectance and tissue imaging systems and methods |
| US7668350B2 (en) * | 2003-04-04 | 2010-02-23 | Lumidigm, Inc. | Comparative texture analysis of tissue for biometric spoof detection |
| US7545963B2 (en) | 2003-04-04 | 2009-06-09 | Lumidigm, Inc. | Texture-biometrics sensor |
| JP2007524441A (ja) * | 2003-04-04 | 2007-08-30 | ルミディム インコーポレイテッド | マルチスペクトルバイオメトリックセンサ |
| US7751594B2 (en) | 2003-04-04 | 2010-07-06 | Lumidigm, Inc. | White-light spectral biometric sensors |
| US7627151B2 (en) * | 2003-04-04 | 2009-12-01 | Lumidigm, Inc. | Systems and methods for improved biometric feature definition |
| US7134999B2 (en) * | 2003-04-04 | 2006-11-14 | Dexcom, Inc. | Optimized sensor geometry for an implantable glucose sensor |
| EP1617888B1 (en) | 2003-04-23 | 2019-06-12 | Valeritas, Inc. | Hydraulically actuated pump for long duration medicament administration |
| US6958039B2 (en) | 2003-05-02 | 2005-10-25 | Oculir, Inc. | Method and instruments for non-invasive analyte measurement |
| US6968222B2 (en) | 2003-05-02 | 2005-11-22 | Oculir, Inc. | Methods and device for non-invasive analyte measurement |
| US6975892B2 (en) | 2003-10-21 | 2005-12-13 | Oculir, Inc. | Methods for non-invasive analyte measurement from the conjunctiva |
| US7875293B2 (en) | 2003-05-21 | 2011-01-25 | Dexcom, Inc. | Biointerface membranes incorporating bioactive agents |
| US7181219B2 (en) * | 2003-05-22 | 2007-02-20 | Lucent Technologies Inc. | Wireless handover using anchor termination |
| US6993372B2 (en) * | 2003-06-03 | 2006-01-31 | Orsense Ltd. | Method and system for use in non-invasive optical measurements of blood parameters |
| US8066639B2 (en) | 2003-06-10 | 2011-11-29 | Abbott Diabetes Care Inc. | Glucose measuring device for use in personal area network |
| US20040259270A1 (en) * | 2003-06-19 | 2004-12-23 | Wolf David E. | System, device and method for exciting a sensor and detecting analyte |
| US20040263857A1 (en) * | 2003-06-24 | 2004-12-30 | Basavanhally Nagesh R. | Fiber-optic gauge having one or more side-mounted sensors |
| FR2856807B1 (fr) * | 2003-06-30 | 2005-09-16 | Yves Agnet | Source lumineuse. |
| US20050007582A1 (en) * | 2003-07-07 | 2005-01-13 | Lumidigm, Inc. | Methods and apparatus for collection of optical reference measurements for monolithic sensors |
| US7695239B2 (en) * | 2003-07-14 | 2010-04-13 | Fortrend Engineering Corporation | End effector gripper arms having corner grippers which reorient reticle during transfer |
| US8282549B2 (en) | 2003-12-09 | 2012-10-09 | Dexcom, Inc. | Signal processing for continuous analyte sensor |
| WO2007120442A2 (en) | 2003-07-25 | 2007-10-25 | Dexcom, Inc. | Dual electrode system for a continuous analyte sensor |
| US8423113B2 (en) | 2003-07-25 | 2013-04-16 | Dexcom, Inc. | Systems and methods for processing sensor data |
| WO2005012871A2 (en) * | 2003-07-25 | 2005-02-10 | Dexcom, Inc. | Increasing bias for oxygen production in an electrode system |
| WO2005012873A2 (en) | 2003-07-25 | 2005-02-10 | Dexcom, Inc. | Electrode systems for electrochemical sensors |
| US8788006B2 (en) | 2003-08-01 | 2014-07-22 | Dexcom, Inc. | System and methods for processing analyte sensor data |
| US20080119703A1 (en) | 2006-10-04 | 2008-05-22 | Mark Brister | Analyte sensor |
| US20190357827A1 (en) | 2003-08-01 | 2019-11-28 | Dexcom, Inc. | Analyte sensor |
| US8275437B2 (en) | 2003-08-01 | 2012-09-25 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US8761856B2 (en) | 2003-08-01 | 2014-06-24 | Dexcom, Inc. | System and methods for processing analyte sensor data |
| US8160669B2 (en) | 2003-08-01 | 2012-04-17 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US7519408B2 (en) * | 2003-11-19 | 2009-04-14 | Dexcom, Inc. | Integrated receiver for continuous analyte sensor |
| US7774145B2 (en) | 2003-08-01 | 2010-08-10 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US8369919B2 (en) | 2003-08-01 | 2013-02-05 | Dexcom, Inc. | Systems and methods for processing sensor data |
| US8886273B2 (en) | 2003-08-01 | 2014-11-11 | Dexcom, Inc. | Analyte sensor |
| US7955261B2 (en) | 2003-08-01 | 2011-06-07 | Dexcom, Inc. | System and methods for processing analyte sensor data |
| US7591801B2 (en) | 2004-02-26 | 2009-09-22 | Dexcom, Inc. | Integrated delivery device for continuous glucose sensor |
| US9135402B2 (en) | 2007-12-17 | 2015-09-15 | Dexcom, Inc. | Systems and methods for processing sensor data |
| US6931327B2 (en) | 2003-08-01 | 2005-08-16 | Dexcom, Inc. | System and methods for processing analyte sensor data |
| US8233959B2 (en) | 2003-08-22 | 2012-07-31 | Dexcom, Inc. | Systems and methods for processing analyte sensor data |
| US7920906B2 (en) | 2005-03-10 | 2011-04-05 | Dexcom, Inc. | System and methods for processing analyte sensor data for sensor calibration |
| US20140121989A1 (en) | 2003-08-22 | 2014-05-01 | Dexcom, Inc. | Systems and methods for processing analyte sensor data |
| US20060224057A1 (en) * | 2003-10-21 | 2006-10-05 | Oculir, Inc. | Methods for non-invasive analyte measurement |
| US20050090607A1 (en) * | 2003-10-28 | 2005-04-28 | Dexcom, Inc. | Silicone composition for biocompatible membrane |
| JP2007512588A (ja) * | 2003-10-29 | 2007-05-17 | ノボ・ノルデイスク・エー／エス | 医療助言システム |
| US7299082B2 (en) | 2003-10-31 | 2007-11-20 | Abbott Diabetes Care, Inc. | Method of calibrating an analyte-measurement device, and associated methods, devices and systems |
| US20050096514A1 (en) * | 2003-11-01 | 2005-05-05 | Medtronic, Inc. | Gastric activity notification |
| USD914881S1 (en) | 2003-11-05 | 2021-03-30 | Abbott Diabetes Care Inc. | Analyte sensor electronic mount |
| US9247900B2 (en) | 2004-07-13 | 2016-02-02 | Dexcom, Inc. | Analyte sensor |
| EP2256493B1 (en) | 2003-12-05 | 2014-02-26 | DexCom, Inc. | Calibration techniques for a continuous analyte sensor |
| US8287453B2 (en) | 2003-12-05 | 2012-10-16 | Dexcom, Inc. | Analyte sensor |
| US11633133B2 (en) | 2003-12-05 | 2023-04-25 | Dexcom, Inc. | Dual electrode system for a continuous analyte sensor |
| US8364231B2 (en) | 2006-10-04 | 2013-01-29 | Dexcom, Inc. | Analyte sensor |
| US8423114B2 (en) | 2006-10-04 | 2013-04-16 | Dexcom, Inc. | Dual electrode system for a continuous analyte sensor |
| US7263213B2 (en) | 2003-12-11 | 2007-08-28 | Lumidigm, Inc. | Methods and systems for estimation of personal characteristics from biometric measurements |
| US20050182451A1 (en) * | 2004-01-12 | 2005-08-18 | Adam Griffin | Implantable device with improved radio frequency capabilities |
| US7637868B2 (en) | 2004-01-12 | 2009-12-29 | Dexcom, Inc. | Composite material for implantable device |
| DE102004004031B4 (de) * | 2004-01-27 | 2019-03-28 | Disetronic Licensing Ag | Abgleich von Sensoren oder Messsystemen |
| US8165651B2 (en) | 2004-02-09 | 2012-04-24 | Abbott Diabetes Care Inc. | Analyte sensor, and associated system and method employing a catalytic agent |
| US7699964B2 (en) * | 2004-02-09 | 2010-04-20 | Abbott Diabetes Care Inc. | Membrane suitable for use in an analyte sensor, analyte sensor, and associated method |
| WO2005079257A2 (en) * | 2004-02-12 | 2005-09-01 | Dexcom, Inc. | Biointerface with macro- and micro- architecture |
| EP1718198A4 (en) | 2004-02-17 | 2008-06-04 | Therasense Inc | METHOD AND SYSTEM FOR PROVIDING DATA COMMUNICATION IN A CONTINUOUS BLOOD SUGAR MONITORING AND MANAGEMENT SYSTEM |
| US7433123B2 (en) | 2004-02-19 | 2008-10-07 | Illumina, Inc. | Optical identification element having non-waveguide photosensitive substrate with diffraction grating therein |
| US8057422B2 (en) * | 2004-02-25 | 2011-11-15 | Wolf Ii Erich W | Transcutaneous telemetry of cerebrospinal fluid shunt programmable-valve pressure using near-infrared (NIR) light |
| WO2005082025A2 (en) * | 2004-02-25 | 2005-09-09 | Wolf Erich W | System for transcutaneous monitoring of intracranial pressure (icp) using near infrared (nir) telemetry |
| US8808228B2 (en) | 2004-02-26 | 2014-08-19 | Dexcom, Inc. | Integrated medicament delivery device for use with continuous analyte sensor |
| US20060258919A1 (en) * | 2004-04-14 | 2006-11-16 | Oculir, Inc. | Non-Invasive Analyte Measurement Device for Measuring Tears and Other Ocular Elements Using Electromagnetic Radiation and Method of Using the Same |
| US20080009688A1 (en) * | 2004-04-14 | 2008-01-10 | Oculir, Inc. | Methods for non-invasive analyte measurement |
| US7223237B2 (en) * | 2004-04-22 | 2007-05-29 | Pacesetter, Inc. | Implantable biosensor and methods for monitoring cardiac health |
| US8792955B2 (en) | 2004-05-03 | 2014-07-29 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US20050245799A1 (en) * | 2004-05-03 | 2005-11-03 | Dexcom, Inc. | Implantable analyte sensor |
| US20050261561A1 (en) * | 2004-05-24 | 2005-11-24 | Christopher W. Jones | Blood testing and therapeutic compound delivery system |
| US7508965B2 (en) * | 2004-06-01 | 2009-03-24 | Lumidigm, Inc. | System and method for robust fingerprint acquisition |
| US8229185B2 (en) * | 2004-06-01 | 2012-07-24 | Lumidigm, Inc. | Hygienic biometric sensors |
| SG137871A1 (en) | 2004-06-01 | 2007-12-28 | In Motion Investment Ltd | In vitro techniques for use with stem cells |
| US20060010098A1 (en) | 2004-06-04 | 2006-01-12 | Goodnow Timothy T | Diabetes care host-client architecture and data management system |
| WO2005120335A2 (en) * | 2004-06-07 | 2005-12-22 | Glucon Inc | Assay apparatus comprising an implanted light source |
| WO2006014425A1 (en) | 2004-07-02 | 2006-02-09 | Biovalve Technologies, Inc. | Methods and devices for delivering glp-1 and uses thereof |
| US20060015020A1 (en) * | 2004-07-06 | 2006-01-19 | Dexcom, Inc. | Systems and methods for manufacture of an analyte-measuring device including a membrane system |
| US8886272B2 (en) | 2004-07-13 | 2014-11-11 | Dexcom, Inc. | Analyte sensor |
| US7783333B2 (en) | 2004-07-13 | 2010-08-24 | Dexcom, Inc. | Transcutaneous medical device with variable stiffness |
| US7905833B2 (en) | 2004-07-13 | 2011-03-15 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US7946984B2 (en) | 2004-07-13 | 2011-05-24 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US20060270922A1 (en) | 2004-07-13 | 2006-11-30 | Brauker James H | Analyte sensor |
| WO2006006166A2 (en) | 2004-07-14 | 2006-01-19 | Glusense, Ltd. | Implantable power sources and sensors |
| US8787630B2 (en) | 2004-08-11 | 2014-07-22 | Lumidigm, Inc. | Multispectral barcode imaging |
| US7522786B2 (en) * | 2005-12-22 | 2009-04-21 | Palo Alto Research Center Incorporated | Transmitting light with photon energy information |
| US20080171913A1 (en) * | 2004-11-15 | 2008-07-17 | Novo Nordisk A/S | Method and Apparatus for Monitoring Long Term and Short Term Effects of a Treatment |
| US7604173B2 (en) | 2004-11-16 | 2009-10-20 | Illumina, Inc. | Holographically encoded elements for microarray and other tagging labeling applications, and method and apparatus for making and reading the same |
| WO2006055735A2 (en) | 2004-11-16 | 2006-05-26 | Illumina, Inc | Scanner having spatial light modulator |
| US9743862B2 (en) | 2011-03-31 | 2017-08-29 | Abbott Diabetes Care Inc. | Systems and methods for transcutaneously implanting medical devices |
| US8545403B2 (en) | 2005-12-28 | 2013-10-01 | Abbott Diabetes Care Inc. | Medical device insertion |
| US9572534B2 (en) | 2010-06-29 | 2017-02-21 | Abbott Diabetes Care Inc. | Devices, systems and methods for on-skin or on-body mounting of medical devices |
| US9788771B2 (en) | 2006-10-23 | 2017-10-17 | Abbott Diabetes Care Inc. | Variable speed sensor insertion devices and methods of use |
| US7697967B2 (en) * | 2005-12-28 | 2010-04-13 | Abbott Diabetes Care Inc. | Method and apparatus for providing analyte sensor insertion |
| US9259175B2 (en) | 2006-10-23 | 2016-02-16 | Abbott Diabetes Care, Inc. | Flexible patch for fluid delivery and monitoring body analytes |
| US8571624B2 (en) | 2004-12-29 | 2013-10-29 | Abbott Diabetes Care Inc. | Method and apparatus for mounting a data transmission device in a communication system |
| US9398882B2 (en) | 2005-09-30 | 2016-07-26 | Abbott Diabetes Care Inc. | Method and apparatus for providing analyte sensor and data processing device |
| US8512243B2 (en) | 2005-09-30 | 2013-08-20 | Abbott Diabetes Care Inc. | Integrated introducer and transmitter assembly and methods of use |
| US10226207B2 (en) | 2004-12-29 | 2019-03-12 | Abbott Diabetes Care Inc. | Sensor inserter having introducer |
| US20090105569A1 (en) | 2006-04-28 | 2009-04-23 | Abbott Diabetes Care, Inc. | Introducer Assembly and Methods of Use |
| US8029441B2 (en) | 2006-02-28 | 2011-10-04 | Abbott Diabetes Care Inc. | Analyte sensor transmitter unit configuration for a data monitoring and management system |
| US8613703B2 (en) * | 2007-05-31 | 2013-12-24 | Abbott Diabetes Care Inc. | Insertion devices and methods |
| US9636450B2 (en) | 2007-02-19 | 2017-05-02 | Udo Hoss | Pump system modular components for delivering medication and analyte sensing at seperate insertion sites |
| US8333714B2 (en) | 2006-09-10 | 2012-12-18 | Abbott Diabetes Care Inc. | Method and system for providing an integrated analyte sensor insertion device and data processing unit |
| US7731657B2 (en) | 2005-08-30 | 2010-06-08 | Abbott Diabetes Care Inc. | Analyte sensor introducer and methods of use |
| US7883464B2 (en) | 2005-09-30 | 2011-02-08 | Abbott Diabetes Care Inc. | Integrated transmitter unit and sensor introducer mechanism and methods of use |
| ITBO20050002A1 (it) * | 2005-01-04 | 2006-07-05 | Giacomo Vespasiani | Metodo e sistema per la gestione interattiva di dati relativi ad una terapia insulinica in autocontrollo per un paziente diabetico |
| US7547281B2 (en) | 2005-02-01 | 2009-06-16 | Medtronic Minimed, Inc. | Algorithm sensor augmented bolus estimator for semi-closed loop infusion system |
| US20060235348A1 (en) * | 2005-02-14 | 2006-10-19 | Callicoat David N | Method of extracting and analyzing the composition of bodily fluids |
| US8251907B2 (en) | 2005-02-14 | 2012-08-28 | Optiscan Biomedical Corporation | System and method for determining a treatment dose for a patient |
| US7785258B2 (en) * | 2005-10-06 | 2010-08-31 | Optiscan Biomedical Corporation | System and method for determining a treatment dose for a patient |
| WO2006094107A1 (en) | 2005-03-01 | 2006-09-08 | Masimo Laboratories, Inc. | Physiological parameter confidence measure |
| US8133178B2 (en) | 2006-02-22 | 2012-03-13 | Dexcom, Inc. | Analyte sensor |
| US8204565B2 (en) * | 2005-04-04 | 2012-06-19 | University Of Iowa Research Foundation | Reagentless optical analyte detection system |
| US8060174B2 (en) | 2005-04-15 | 2011-11-15 | Dexcom, Inc. | Analyte sensing biointerface |
| US7801338B2 (en) | 2005-04-27 | 2010-09-21 | Lumidigm, Inc. | Multispectral biometric sensors |
| US8112240B2 (en) | 2005-04-29 | 2012-02-07 | Abbott Diabetes Care Inc. | Method and apparatus for providing leak detection in data monitoring and management systems |
| US20070027374A1 (en) * | 2005-05-19 | 2007-02-01 | Foss Analytical Ab | Optical blood analyte monitor |
| WO2006133348A2 (en) * | 2005-06-08 | 2006-12-14 | Philip Michael Sher | Fluctuating blood glucose notification threshold profiles and methods of use |
| US7835599B2 (en) | 2005-08-25 | 2010-11-16 | Institut National D'optique | Flow cytometry analysis across optical fiber |
| US20080314395A1 (en) | 2005-08-31 | 2008-12-25 | Theuniversity Of Virginia Patent Foundation | Accuracy of Continuous Glucose Sensors |
| JP2009507569A (ja) * | 2005-09-13 | 2009-02-26 | エドワーズ ライフサイエンシーズ コーポレイション | 総ヘモグロビンの継続的な分光測定 |
| US8880138B2 (en) | 2005-09-30 | 2014-11-04 | Abbott Diabetes Care Inc. | Device for channeling fluid and methods of use |
| US9521968B2 (en) | 2005-09-30 | 2016-12-20 | Abbott Diabetes Care Inc. | Analyte sensor retention mechanism and methods of use |
| US7766829B2 (en) | 2005-11-04 | 2010-08-03 | Abbott Diabetes Care Inc. | Method and system for providing basal profile modification in analyte monitoring and management systems |
| US7729737B2 (en) | 2005-11-22 | 2010-06-01 | Isense Corporation | Method and apparatus for background current arrangements for a biosensor |
| US7623624B2 (en) * | 2005-11-22 | 2009-11-24 | Illumina, Inc. | Method and apparatus for labeling using optical identification elements characterized by X-ray diffraction |
| US8437582B2 (en) * | 2005-12-22 | 2013-05-07 | Palo Alto Research Center Incorporated | Transmitting light with lateral variation |
| US7433552B2 (en) | 2005-12-22 | 2008-10-07 | Palo Alto Research Center Incorporated | Obtaining analyte information |
| US8515518B2 (en) | 2005-12-28 | 2013-08-20 | Abbott Diabetes Care Inc. | Analyte monitoring |
| US11298058B2 (en) | 2005-12-28 | 2022-04-12 | Abbott Diabetes Care Inc. | Method and apparatus for providing analyte sensor insertion |
| US8160670B2 (en) | 2005-12-28 | 2012-04-17 | Abbott Diabetes Care Inc. | Analyte monitoring: stabilizer for subcutaneous glucose sensor with incorporated antiglycolytic agent |
| US7985330B2 (en) * | 2005-12-30 | 2011-07-26 | Medtronic Minimed, Inc. | Method and system for detecting age, hydration, and functional states of sensors using electrochemical impedance spectroscopy |
| US8114268B2 (en) * | 2005-12-30 | 2012-02-14 | Medtronic Minimed, Inc. | Method and system for remedying sensor malfunctions detected by electrochemical impedance spectroscopy |
| US8114269B2 (en) | 2005-12-30 | 2012-02-14 | Medtronic Minimed, Inc. | System and method for determining the point of hydration and proper time to apply potential to a glucose sensor |
| US7736310B2 (en) | 2006-01-30 | 2010-06-15 | Abbott Diabetes Care Inc. | On-body medical device securement |
| US7826879B2 (en) | 2006-02-28 | 2010-11-02 | Abbott Diabetes Care Inc. | Analyte sensors and methods of use |
| US7885698B2 (en) | 2006-02-28 | 2011-02-08 | Abbott Diabetes Care Inc. | Method and system for providing continuous calibration of implantable analyte sensors |
| TW200734462A (en) * | 2006-03-08 | 2007-09-16 | In Motion Invest Ltd | Regulating stem cells |
| ES2656675T3 (es) | 2006-03-30 | 2018-02-28 | Valeritas, Inc. | Dispositivo de suministro de fluidos de múltiples cartuchos |
| US7725272B2 (en) * | 2006-03-30 | 2010-05-25 | Codman Neuro Sciences, Sarl | Methods and devices for monitoring fluid of an implantable infusion pump |
| US9326709B2 (en) | 2010-03-10 | 2016-05-03 | Abbott Diabetes Care Inc. | Systems, devices and methods for managing glucose levels |
| US8374668B1 (en) | 2007-10-23 | 2013-02-12 | Abbott Diabetes Care Inc. | Analyte sensor with lag compensation |
| US7801582B2 (en) | 2006-03-31 | 2010-09-21 | Abbott Diabetes Care Inc. | Analyte monitoring and management system and methods therefor |
| US9675290B2 (en) | 2012-10-30 | 2017-06-13 | Abbott Diabetes Care Inc. | Sensitivity calibration of in vivo sensors used to measure analyte concentration |
| US7618369B2 (en) | 2006-10-02 | 2009-11-17 | Abbott Diabetes Care Inc. | Method and system for dynamically updating calibration parameters for an analyte sensor |
| US7620438B2 (en) | 2006-03-31 | 2009-11-17 | Abbott Diabetes Care Inc. | Method and system for powering an electronic device |
| US8224415B2 (en) | 2009-01-29 | 2012-07-17 | Abbott Diabetes Care Inc. | Method and device for providing offset model based calibration for analyte sensor |
| US8140312B2 (en) | 2007-05-14 | 2012-03-20 | Abbott Diabetes Care Inc. | Method and system for determining analyte levels |
| US7630748B2 (en) | 2006-10-25 | 2009-12-08 | Abbott Diabetes Care Inc. | Method and system for providing analyte monitoring |
| US8219173B2 (en) | 2008-09-30 | 2012-07-10 | Abbott Diabetes Care Inc. | Optimizing analyte sensor calibration |
| US9392969B2 (en) | 2008-08-31 | 2016-07-19 | Abbott Diabetes Care Inc. | Closed loop control and signal attenuation detection |
| US8226891B2 (en) | 2006-03-31 | 2012-07-24 | Abbott Diabetes Care Inc. | Analyte monitoring devices and methods therefor |
| US8478557B2 (en) | 2009-07-31 | 2013-07-02 | Abbott Diabetes Care Inc. | Method and apparatus for providing analyte monitoring system calibration accuracy |
| US7653425B2 (en) * | 2006-08-09 | 2010-01-26 | Abbott Diabetes Care Inc. | Method and system for providing calibration of an analyte sensor in an analyte monitoring system |
| US8346335B2 (en) | 2008-03-28 | 2013-01-01 | Abbott Diabetes Care Inc. | Analyte sensor calibration management |
| US8583205B2 (en) | 2008-03-28 | 2013-11-12 | Abbott Diabetes Care Inc. | Analyte sensor calibration management |
| US8473022B2 (en) | 2008-01-31 | 2013-06-25 | Abbott Diabetes Care Inc. | Analyte sensor with time lag compensation |
| US7830575B2 (en) | 2006-04-10 | 2010-11-09 | Illumina, Inc. | Optical scanner with improved scan time |
| US20070254381A1 (en) * | 2006-04-27 | 2007-11-01 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Monitoring and/or treating syringe mechanism |
| US8126554B2 (en) * | 2006-05-17 | 2012-02-28 | Cardiac Pacemakers, Inc. | Implantable medical device with chemical sensor and related methods |
| US20080071158A1 (en) | 2006-06-07 | 2008-03-20 | Abbott Diabetes Care, Inc. | Analyte monitoring system and method |
| US7899217B2 (en) * | 2006-07-19 | 2011-03-01 | Lumidign, Inc. | Multibiometric multispectral imager |
| US7995808B2 (en) * | 2006-07-19 | 2011-08-09 | Lumidigm, Inc. | Contactless multispectral biometric capture |
| US8355545B2 (en) * | 2007-04-10 | 2013-01-15 | Lumidigm, Inc. | Biometric detection using spatial, temporal, and/or spectral techniques |
| US8175346B2 (en) * | 2006-07-19 | 2012-05-08 | Lumidigm, Inc. | Whole-hand multispectral biometric imaging |
| US20110054391A1 (en) * | 2006-07-28 | 2011-03-03 | Ward W Kenneth | Analyte sensing and response system |
| US8114023B2 (en) | 2006-07-28 | 2012-02-14 | Legacy Emanuel Hospital & Health Center | Analyte sensing and response system |
| US7804984B2 (en) | 2006-07-31 | 2010-09-28 | Lumidigm, Inc. | Spatial-spectral fingerprint spoof detection |
| US7801339B2 (en) | 2006-07-31 | 2010-09-21 | Lumidigm, Inc. | Biometrics with spatiospectral spoof detection |
| US8536542B2 (en) | 2006-08-25 | 2013-09-17 | Institut National D'optique | Flow cytometry analysis across optical fiber |
| EP2063762A1 (en) * | 2006-09-06 | 2009-06-03 | Medingo Ltd. | Fluid delivery system with optical sensing of analyte concentration levels |
| CA2701006C (en) * | 2006-09-27 | 2016-07-12 | University Of Connecticut | Implantable biosensor and methods of use thereof |
| US8396524B2 (en) * | 2006-09-27 | 2013-03-12 | Covidien Lp | Medical sensor and technique for using the same |
| US8265723B1 (en) * | 2006-10-12 | 2012-09-11 | Cercacor Laboratories, Inc. | Oximeter probe off indicator defining probe off space |
| JP2010508091A (ja) | 2006-10-26 | 2010-03-18 | アボット ダイアベティス ケア インコーポレイテッド | 検体センサの感度低下をリアルタイムで検出するための方法、システム、及びコンピュータプログラム製品 |
| EP2097508A4 (en) * | 2006-12-07 | 2011-10-26 | Univ Ohio State Res Found | SYSTEM FOR IN VIVO BIOSENSING BASED ON THE OPTICAL REACTION OF ELECTRONIC POLYMERS |
| US7946985B2 (en) * | 2006-12-29 | 2011-05-24 | Medtronic Minimed, Inc. | Method and system for providing sensor redundancy |
| US20080214912A1 (en) * | 2007-01-10 | 2008-09-04 | Glucose Sensing Technologies, Llc | Blood Glucose Monitoring System And Method |
| US9164037B2 (en) * | 2007-01-26 | 2015-10-20 | Palo Alto Research Center Incorporated | Method and system for evaluation of signals received from spatially modulated excitation and emission to accurately determine particle positions and distances |
| US8821799B2 (en) | 2007-01-26 | 2014-09-02 | Palo Alto Research Center Incorporated | Method and system implementing spatially modulated excitation or emission for particle characterization with enhanced sensitivity |
| US7545513B2 (en) * | 2007-02-05 | 2009-06-09 | Palo Alto Research Center Incorporated | Encoding optical cavity output light |
| US7502123B2 (en) * | 2007-02-05 | 2009-03-10 | Palo Alto Research Center Incorporated | Obtaining information from optical cavity output light |
| US7936463B2 (en) * | 2007-02-05 | 2011-05-03 | Palo Alto Research Center Incorporated | Containing analyte in optical cavity structures |
| US7817276B2 (en) * | 2007-02-05 | 2010-10-19 | Palo Alto Research Center Incorporated | Distinguishing objects |
| US7633629B2 (en) * | 2007-02-05 | 2009-12-15 | Palo Alto Research Center Incorporated | Tuning optical cavities |
| US7471399B2 (en) * | 2007-02-05 | 2008-12-30 | Palo Alto Research Center Incorporated | Photosensing optical cavity output light |
| US20080199894A1 (en) | 2007-02-15 | 2008-08-21 | Abbott Diabetes Care, Inc. | Device and method for automatic data acquisition and/or detection |
| US8121857B2 (en) | 2007-02-15 | 2012-02-21 | Abbott Diabetes Care Inc. | Device and method for automatic data acquisition and/or detection |
| US8732188B2 (en) | 2007-02-18 | 2014-05-20 | Abbott Diabetes Care Inc. | Method and system for providing contextual based medication dosage determination |
| US8930203B2 (en) | 2007-02-18 | 2015-01-06 | Abbott Diabetes Care Inc. | Multi-function analyte test device and methods therefor |
| WO2008106608A1 (en) * | 2007-02-28 | 2008-09-04 | Medtronic, Inc. | Implantable tissue perfusion sensing system and method |
| US8123686B2 (en) | 2007-03-01 | 2012-02-28 | Abbott Diabetes Care Inc. | Method and apparatus for providing rolling data in communication systems |
| EP2120713A2 (en) * | 2007-03-21 | 2009-11-25 | Lumidigm, Inc. | Biometrics based on locally consistent features |
| US20080255433A1 (en) * | 2007-04-11 | 2008-10-16 | The Board Of Regents Of The University Of Texas Syatem | Optoacoustic monitoring of multiple parameters |
| WO2008130896A1 (en) | 2007-04-14 | 2008-10-30 | Abbott Diabetes Care, Inc. | Method and apparatus for providing data processing and control in medical communication system |
| WO2008130895A2 (en) | 2007-04-14 | 2008-10-30 | Abbott Diabetes Care, Inc. | Method and apparatus for providing dynamic multi-stage signal amplification in a medical device |
| EP3741291A1 (en) | 2007-04-14 | 2020-11-25 | Abbott Diabetes Care, Inc. | Method and apparatus for providing data processing and control in medical communication system |
| US9008743B2 (en) | 2007-04-14 | 2015-04-14 | Abbott Diabetes Care Inc. | Method and apparatus for providing data processing and control in medical communication system |
| US8140142B2 (en) | 2007-04-14 | 2012-03-20 | Abbott Diabetes Care Inc. | Method and apparatus for providing data processing and control in medical communication system |
| CA2683959C (en) | 2007-04-14 | 2017-08-29 | Abbott Diabetes Care Inc. | Method and apparatus for providing data processing and control in medical communication system |
| US20080269714A1 (en) | 2007-04-25 | 2008-10-30 | Medtronic Minimed, Inc. | Closed loop/semi-closed loop therapy modification system |
| US20080269723A1 (en) * | 2007-04-25 | 2008-10-30 | Medtronic Minimed, Inc. | Closed loop/semi-closed loop therapy modification system |
| US8461985B2 (en) | 2007-05-08 | 2013-06-11 | Abbott Diabetes Care Inc. | Analyte monitoring system and methods |
| US7928850B2 (en) | 2007-05-08 | 2011-04-19 | Abbott Diabetes Care Inc. | Analyte monitoring system and methods |
| US8665091B2 (en) | 2007-05-08 | 2014-03-04 | Abbott Diabetes Care Inc. | Method and device for determining elapsed sensor life |
| US8456301B2 (en) | 2007-05-08 | 2013-06-04 | Abbott Diabetes Care Inc. | Analyte monitoring system and methods |
| US8260558B2 (en) | 2007-05-14 | 2012-09-04 | Abbott Diabetes Care Inc. | Method and apparatus for providing data processing and control in a medical communication system |
| US8103471B2 (en) | 2007-05-14 | 2012-01-24 | Abbott Diabetes Care Inc. | Method and apparatus for providing data processing and control in a medical communication system |
| US9125548B2 (en) | 2007-05-14 | 2015-09-08 | Abbott Diabetes Care Inc. | Method and apparatus for providing data processing and control in a medical communication system |
| US8444560B2 (en) | 2007-05-14 | 2013-05-21 | Abbott Diabetes Care Inc. | Method and apparatus for providing data processing and control in a medical communication system |
| US10002233B2 (en) | 2007-05-14 | 2018-06-19 | Abbott Diabetes Care Inc. | Method and apparatus for providing data processing and control in a medical communication system |
| US7996158B2 (en) | 2007-05-14 | 2011-08-09 | Abbott Diabetes Care Inc. | Method and apparatus for providing data processing and control in a medical communication system |
| US8560038B2 (en) | 2007-05-14 | 2013-10-15 | Abbott Diabetes Care Inc. | Method and apparatus for providing data processing and control in a medical communication system |
| US8239166B2 (en) | 2007-05-14 | 2012-08-07 | Abbott Diabetes Care Inc. | Method and apparatus for providing data processing and control in a medical communication system |
| US8600681B2 (en) | 2007-05-14 | 2013-12-03 | Abbott Diabetes Care Inc. | Method and apparatus for providing data processing and control in a medical communication system |
| US8417311B2 (en) * | 2008-09-12 | 2013-04-09 | Optiscan Biomedical Corporation | Fluid component analysis system and method for glucose monitoring and control |
| EP2152350A4 (en) | 2007-06-08 | 2013-03-27 | Dexcom Inc | INTEGRATED MEDICATION RELEASE DEVICE WITH CONTINUOUS ANALYTICAL SENSOR |
| JP5680960B2 (ja) | 2007-06-21 | 2015-03-04 | アボット ダイアベティス ケア インコーポレイテッドＡｂｂｏｔｔ Ｄｉａｂｅｔｅｓ Ｃａｒｅ Ｉｎｃ． | 健康管理装置および方法 |
| EP3473167A1 (en) | 2007-06-21 | 2019-04-24 | Abbott Diabetes Care, Inc. | Health monitor |
| US8160900B2 (en) | 2007-06-29 | 2012-04-17 | Abbott Diabetes Care Inc. | Analyte monitoring and management device and method to analyze the frequency of user interaction with the device |
| US8834366B2 (en) | 2007-07-31 | 2014-09-16 | Abbott Diabetes Care Inc. | Method and apparatus for providing analyte sensor calibration |
| US7768386B2 (en) * | 2007-07-31 | 2010-08-03 | Abbott Diabetes Care Inc. | Method and apparatus for providing data processing and control in a medical communication system |
| EP2227132B1 (en) | 2007-10-09 | 2023-03-08 | DexCom, Inc. | Integrated insulin delivery system with continuous glucose sensor |
| JP5587782B2 (ja) | 2007-10-10 | 2014-09-10 | オプテイスカン・バイオメデイカル・コーポレーシヨン | グルコースのモニターおよび調節のための流体成分分析システムおよび方法 |
| US8377031B2 (en) | 2007-10-23 | 2013-02-19 | Abbott Diabetes Care Inc. | Closed loop control system with safety parameters and methods |
| US8216138B1 (en) | 2007-10-23 | 2012-07-10 | Abbott Diabetes Care Inc. | Correlation of alternative site blood and interstitial fluid glucose concentrations to venous glucose concentration |
| US8409093B2 (en) | 2007-10-23 | 2013-04-02 | Abbott Diabetes Care Inc. | Assessing measures of glycemic variability |
| US8417312B2 (en) | 2007-10-25 | 2013-04-09 | Dexcom, Inc. | Systems and methods for processing sensor data |
| US7783442B2 (en) * | 2007-10-31 | 2010-08-24 | Medtronic Minimed, Inc. | System and methods for calibrating physiological characteristic sensors |
| WO2009066287A2 (en) | 2007-11-21 | 2009-05-28 | Medingo Ltd. | Hypodermic optical monitoring of bodily analyte |
| US8320983B2 (en) * | 2007-12-17 | 2012-11-27 | Palo Alto Research Center Incorporated | Controlling transfer of objects affecting optical characteristics |
| US8290559B2 (en) | 2007-12-17 | 2012-10-16 | Dexcom, Inc. | Systems and methods for processing sensor data |
| US20090164239A1 (en) | 2007-12-19 | 2009-06-25 | Abbott Diabetes Care, Inc. | Dynamic Display Of Glucose Information |
| US20090192742A1 (en) * | 2008-01-30 | 2009-07-30 | Mensur Omerbashich | Procedure for increasing spectrum accuracy |
| US8629981B2 (en) | 2008-02-01 | 2014-01-14 | Palo Alto Research Center Incorporated | Analyzers with time variation based on color-coded spatial modulation |
| US8373860B2 (en) | 2008-02-01 | 2013-02-12 | Palo Alto Research Center Incorporated | Transmitting/reflecting emanating light with time variation |
| EP2244761A2 (en) * | 2008-02-20 | 2010-11-03 | Dexcom, Inc. | Continous medicament sensor system for in vivo use |
| US8229535B2 (en) | 2008-02-21 | 2012-07-24 | Dexcom, Inc. | Systems and methods for blood glucose monitoring and alert delivery |
| US20090242399A1 (en) * | 2008-03-25 | 2009-10-01 | Dexcom, Inc. | Analyte sensor |
| US20090259214A1 (en) * | 2008-04-09 | 2009-10-15 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Agent delivery device |
| ES2546087T3 (es) | 2008-04-10 | 2015-09-18 | Abbott Diabetes Care Inc. | Procedimiento y sistema para esterilizar un detector de analitos |
| JP5509071B2 (ja) | 2008-04-24 | 2014-06-04 | アークレイ株式会社 | 血糖値制御システム |
| CN102014746A (zh) * | 2008-05-02 | 2011-04-13 | Sri国际公司 | 基于光学显微针的光谱仪 |
| US8924159B2 (en) | 2008-05-30 | 2014-12-30 | Abbott Diabetes Care Inc. | Method and apparatus for providing glycemic control |
| US8591410B2 (en) | 2008-05-30 | 2013-11-26 | Abbott Diabetes Care Inc. | Method and apparatus for providing glycemic control |
| US7826382B2 (en) | 2008-05-30 | 2010-11-02 | Abbott Diabetes Care Inc. | Close proximity communication device and methods |
| US20100030040A1 (en) | 2008-08-04 | 2010-02-04 | Masimo Laboratories, Inc. | Multi-stream data collection system for noninvasive measurement of blood constituents |
| EP2326239B1 (en) * | 2008-07-03 | 2017-06-21 | Masimo Laboratories, Inc. | Protrusion for improving spectroscopic measurement of blood constituents |
| US8876755B2 (en) | 2008-07-14 | 2014-11-04 | Abbott Diabetes Care Inc. | Closed loop control system interface and methods |
| US7959598B2 (en) | 2008-08-20 | 2011-06-14 | Asante Solutions, Inc. | Infusion pump systems and methods |
| US8622988B2 (en) | 2008-08-31 | 2014-01-07 | Abbott Diabetes Care Inc. | Variable rate closed loop control and methods |
| US9943644B2 (en) | 2008-08-31 | 2018-04-17 | Abbott Diabetes Care Inc. | Closed loop control with reference measurement and methods thereof |
| US20100057040A1 (en) | 2008-08-31 | 2010-03-04 | Abbott Diabetes Care, Inc. | Robust Closed Loop Control And Methods |
| US8734422B2 (en) | 2008-08-31 | 2014-05-27 | Abbott Diabetes Care Inc. | Closed loop control with improved alarm functions |
| US8986208B2 (en) | 2008-09-30 | 2015-03-24 | Abbott Diabetes Care Inc. | Analyte sensor sensitivity attenuation mitigation |
| US9149220B2 (en) | 2011-04-15 | 2015-10-06 | Dexcom, Inc. | Advanced analyte sensor calibration and error detection |
| US9326707B2 (en) | 2008-11-10 | 2016-05-03 | Abbott Diabetes Care Inc. | Alarm characterization for analyte monitoring devices and systems |
| RU2500103C2 (ru) * | 2008-11-28 | 2013-12-10 | Терумо Кабусики Кайся | Контейнерная система для крови и кассета |
| CN102333478B (zh) * | 2008-12-24 | 2014-12-10 | 葡萄糖传感器公司 | 可植入的光学葡萄糖感测 |
| US20100160749A1 (en) * | 2008-12-24 | 2010-06-24 | Glusense Ltd. | Implantable optical glucose sensing |
| US8103456B2 (en) | 2009-01-29 | 2012-01-24 | Abbott Diabetes Care Inc. | Method and device for early signal attenuation detection using blood glucose measurements |
| US9402544B2 (en) | 2009-02-03 | 2016-08-02 | Abbott Diabetes Care Inc. | Analyte sensor and apparatus for insertion of the sensor |
| US20100246902A1 (en) * | 2009-02-26 | 2010-09-30 | Lumidigm, Inc. | Method and apparatus to combine biometric sensing and other functionality |
| WO2010107879A1 (en) * | 2009-03-18 | 2010-09-23 | Freeslate, Inc. | Sensor, sensor array, and sensor system for sensing a characteristic of an environment and method of sensing the characteristic |
| EP2410910A4 (en) * | 2009-03-27 | 2014-10-15 | Dexcom Inc | METHODS AND SYSTEMS FOR PROMOTING GLUCOSE MANAGEMENT |
| WO2010121084A1 (en) | 2009-04-15 | 2010-10-21 | Abbott Diabetes Care Inc. | Analyte monitoring system having an alert |
| US9226701B2 (en) | 2009-04-28 | 2016-01-05 | Abbott Diabetes Care Inc. | Error detection in critical repeating data in a wireless sensor system |
| WO2010127051A1 (en) | 2009-04-29 | 2010-11-04 | Abbott Diabetes Care Inc. | Method and system for providing real time analyte sensor calibration with retrospective backfill |
| WO2010127187A1 (en) | 2009-04-29 | 2010-11-04 | Abbott Diabetes Care Inc. | Method and system for providing data communication in continuous glucose monitoring and management system |
| WO2010135646A1 (en) | 2009-05-22 | 2010-11-25 | Abbott Diabetes Care Inc. | Usability features for integrated insulin delivery system |
| US9184490B2 (en) | 2009-05-29 | 2015-11-10 | Abbott Diabetes Care Inc. | Medical device antenna systems having external antenna configurations |
| US8613892B2 (en) | 2009-06-30 | 2013-12-24 | Abbott Diabetes Care Inc. | Analyte meter with a moveable head and methods of using the same |
| CN102469966B (zh) | 2009-07-23 | 2015-05-13 | 雅培糖尿病护理公司 | 持续分析物测量系统和用于植入它们的系统和方法 |
| US11169010B2 (en) * | 2009-07-27 | 2021-11-09 | Integra Lifesciences Switzerland Sàrl | Method for the calibration of an implantable sensor |
| WO2011028620A1 (en) * | 2009-08-26 | 2011-03-10 | Lumidigm, Inc. | Multiplexed biometric imaging and dual-imager biometric sensor |
| WO2011026147A1 (en) | 2009-08-31 | 2011-03-03 | Abbott Diabetes Care Inc. | Analyte signal processing device and methods |
| CN105686807B (zh) | 2009-08-31 | 2019-11-15 | 雅培糖尿病护理公司 | 医疗设备 |
| ES3031591T3 (en) | 2009-08-31 | 2025-07-09 | Abbott Diabetes Care Inc | Displays for a medical device |
| WO2011026148A1 (en) | 2009-08-31 | 2011-03-03 | Abbott Diabetes Care Inc. | Analyte monitoring system and methods for managing power and noise |
| US8688183B2 (en) | 2009-09-03 | 2014-04-01 | Ceracor Laboratories, Inc. | Emitter driver for noninvasive patient monitor |
| US8494604B2 (en) * | 2009-09-21 | 2013-07-23 | Covidien Lp | Wavelength-division multiplexing in a multi-wavelength photon density wave system |
| WO2011041469A1 (en) | 2009-09-29 | 2011-04-07 | Abbott Diabetes Care Inc. | Method and apparatus for providing notification function in analyte monitoring systems |
| WO2011041531A1 (en) | 2009-09-30 | 2011-04-07 | Abbott Diabetes Care Inc. | Interconnect for on-body analyte monitoring device |
| US8185181B2 (en) | 2009-10-30 | 2012-05-22 | Abbott Diabetes Care Inc. | Method and apparatus for detecting false hypoglycemic conditions |
| US9839381B1 (en) | 2009-11-24 | 2017-12-12 | Cercacor Laboratories, Inc. | Physiological measurement system with automatic wavelength adjustment |
| US9936574B2 (en) * | 2009-12-16 | 2018-04-03 | The Board Of Trustees Of The University Of Illinois | Waterproof stretchable optoelectronics |
| USD924406S1 (en) | 2010-02-01 | 2021-07-06 | Abbott Diabetes Care Inc. | Analyte sensor inserter |
| US8570149B2 (en) | 2010-03-16 | 2013-10-29 | Lumidigm, Inc. | Biometric imaging using an optical adaptive interface |
| EP2552532A1 (en) | 2010-03-24 | 2013-02-06 | Abbott Diabetes Care, Inc. | Medical device inserters and processes of inserting and using medical devices |
| US8636711B2 (en) | 2010-06-14 | 2014-01-28 | Legacy Emanuel Hospital & Health Center | Stabilized glucagon solutions and uses therefor |
| EP2399509A1 (de) * | 2010-06-22 | 2011-12-28 | Senspec GmbH | Vorrichtung und Verfahren zum Erkennen und Überwachen von physiologischen Blutwerten |
| US8635046B2 (en) | 2010-06-23 | 2014-01-21 | Abbott Diabetes Care Inc. | Method and system for evaluating analyte sensor response characteristics |
| US10092229B2 (en) | 2010-06-29 | 2018-10-09 | Abbott Diabetes Care Inc. | Calibration of analyte measurement system |
| US11064921B2 (en) | 2010-06-29 | 2021-07-20 | Abbott Diabetes Care Inc. | Devices, systems and methods for on-skin or on-body mounting of medical devices |
| US20120078570A1 (en) * | 2010-09-29 | 2012-03-29 | Apple Inc. | Multiple accelerometer system |
| WO2012048168A2 (en) | 2010-10-07 | 2012-04-12 | Abbott Diabetes Care Inc. | Analyte monitoring devices and methods |
| US8489168B2 (en) * | 2010-11-18 | 2013-07-16 | Medtronic, Inc. | Coefficent determination for blood oxygen saturation and total hemoglobin concentration indices |
| CA3277222A1 (en) | 2011-02-28 | 2025-10-30 | Abbott Diabetes Care Inc. | Devices, systems, and methods associated with analyte monitoring devices and devices incorporating the same |
| US10136845B2 (en) | 2011-02-28 | 2018-11-27 | Abbott Diabetes Care Inc. | Devices, systems, and methods associated with analyte monitoring devices and devices incorporating the same |
| AU2012240669B2 (en) * | 2011-04-06 | 2016-02-04 | Klein Medical Limited | Spectroscopic analyser |
| EP3556285B1 (en) | 2011-06-16 | 2022-08-31 | Abbott Diabetes Care, Inc. | Temperature-compensated analyte monitoring devices, systems, and methods thereof |
| WO2012178134A2 (en) * | 2011-06-23 | 2012-12-27 | University Of Virginia Patent Foundation | Unified platform for monitoring and control of blood glucose levels in diabetic patients |
| US9037205B2 (en) | 2011-06-30 | 2015-05-19 | Glusense, Ltd | Implantable optical glucose sensing |
| US10575762B2 (en) | 2011-08-05 | 2020-03-03 | Dexcom, Inc. | Systems and methods for detecting glucose level data patterns |
| US9029800B2 (en) | 2011-08-09 | 2015-05-12 | Palo Alto Research Center Incorporated | Compact analyzer with spatial modulation and multiple intensity modulated excitation sources |
| US8723140B2 (en) | 2011-08-09 | 2014-05-13 | Palo Alto Research Center Incorporated | Particle analyzer with spatial modulation and long lifetime bioprobes |
| US9069536B2 (en) | 2011-10-31 | 2015-06-30 | Abbott Diabetes Care Inc. | Electronic devices having integrated reset systems and methods thereof |
| WO2013066849A1 (en) | 2011-10-31 | 2013-05-10 | Abbott Diabetes Care Inc. | Model based variable risk false glucose threshold alarm prevention mechanism |
| AU2012335830B2 (en) | 2011-11-07 | 2017-05-04 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods |
| US9317656B2 (en) | 2011-11-23 | 2016-04-19 | Abbott Diabetes Care Inc. | Compatibility mechanisms for devices in a continuous analyte monitoring system and methods thereof |
| US8710993B2 (en) | 2011-11-23 | 2014-04-29 | Abbott Diabetes Care Inc. | Mitigating single point failure of devices in an analyte monitoring system and methods thereof |
| WO2013078426A2 (en) | 2011-11-25 | 2013-05-30 | Abbott Diabetes Care Inc. | Analyte monitoring system and methods of use |
| US9402570B2 (en) | 2011-12-11 | 2016-08-02 | Abbott Diabetes Care Inc. | Analyte sensor devices, connections, and methods |
| WO2013149186A1 (en) | 2012-03-30 | 2013-10-03 | Insulet Corporation | Fluid delivery device with transcutaneous access tool, insertion mechansim and blood glucose monitoring for use therewith |
| US10004438B2 (en) * | 2012-04-20 | 2018-06-26 | University Of Rochester | Implantable real-time oximeter to determine potential strokes and post-traumatic brain-injury complications |
| WO2013185213A1 (en) * | 2012-06-15 | 2013-12-19 | Handyem Inc. | Method and flow cell for characterizing particles by means of non-gaussian temporal signals |
| WO2014035732A1 (en) | 2012-08-30 | 2014-03-06 | Abbot Diabetes Care Inc. | Dropout detection in continuous analyte monitoring data during data excursions |
| US9968306B2 (en) | 2012-09-17 | 2018-05-15 | Abbott Diabetes Care Inc. | Methods and apparatuses for providing adverse condition notification with enhanced wireless communication range in analyte monitoring systems |
| EP2901153A4 (en) | 2012-09-26 | 2016-04-27 | Abbott Diabetes Care Inc | METHOD AND DEVICE FOR IMPROVING DELAY CORRECTION FUNCTION DURING IN VIVO MEASUREMENT OF ANALYZ CONCENTRATION WITH ANALYZ CONCENTRATION VARIABILITY AND RANGE DATA |
| WO2014099124A1 (en) * | 2012-12-21 | 2014-06-26 | Tufts University | Coherent hemodynamics spectroscopy and model based characterization of physiological systems |
| EP2948049B1 (en) | 2013-01-24 | 2024-04-24 | Alio, Inc. | Prosthesis for measuring fluid flow through a lumen |
| US9474475B1 (en) | 2013-03-15 | 2016-10-25 | Abbott Diabetes Care Inc. | Multi-rate analyte sensor data collection with sample rate configurable signal processing |
| US10433773B1 (en) | 2013-03-15 | 2019-10-08 | Abbott Diabetes Care Inc. | Noise rejection methods and apparatus for sparsely sampled analyte sensor data |
| WO2014152034A1 (en) | 2013-03-15 | 2014-09-25 | Abbott Diabetes Care Inc. | Sensor fault detection using analyte sensor data pattern comparison |
| US9561324B2 (en) | 2013-07-19 | 2017-02-07 | Bigfoot Biomedical, Inc. | Infusion pump system and method |
| CA2927883A1 (en) * | 2013-10-22 | 2015-04-30 | Koninklijke Philips N.V. | Sensor apparatus and method for monitoring a vital sign of a subject |
| US9770196B2 (en) | 2013-11-27 | 2017-09-26 | Universiteit Gent | Sensing of components in liquids |
| EP3089666B1 (en) | 2013-12-31 | 2020-08-19 | Abbott Diabetes Care Inc. | Self-powered analyte sensor and devices using the same |
| GB2523989B (en) | 2014-01-30 | 2020-07-29 | Insulet Netherlands B V | Therapeutic product delivery system and method of pairing |
| WO2015153482A1 (en) | 2014-03-30 | 2015-10-08 | Abbott Diabetes Care Inc. | Method and apparatus for determining meal start and peak events in analyte monitoring systems |
| US10441717B2 (en) | 2014-04-15 | 2019-10-15 | Insulet Corporation | Monitoring a physiological parameter associated with tissue of a host to confirm delivery of medication |
| EP3180065A4 (en) | 2014-07-24 | 2018-04-11 | Thomas Jefferson University | Long-term implantable monitoring system & methods of use |
| EP3206567A1 (en) | 2014-10-13 | 2017-08-23 | Glusense, Ltd. | Analyte-sensing device |
| US10292592B2 (en) * | 2014-11-13 | 2019-05-21 | The Board Of Trustees Of The Leland Stanford Junior University | Method and apparatus for optical recording of biological parameters in freely moving animals |
| CA2972253A1 (en) | 2014-12-23 | 2016-06-30 | Zolo Technologies, Inc. | Tdlas architecture for widely spaced wavelengths |
| AU2016219961B2 (en) | 2015-02-18 | 2020-07-02 | Insulet Corporation | Fluid delivery and infusion devices, and methods of use thereof |
| US9924905B2 (en) | 2015-03-09 | 2018-03-27 | Graftworx, Inc. | Sensor position on a prosthesis for detection of a stenosis |
| US11330987B2 (en) | 2015-04-06 | 2022-05-17 | Thomas Jefferson University | Implantable vital sign sensor |
| US11000195B2 (en) | 2015-04-06 | 2021-05-11 | Thomas Jefferson University | Implantable vital sign sensor |
| US10335043B2 (en) | 2015-04-06 | 2019-07-02 | Thomas Jefferson University | Implantable vital sign sensor |
| CN107708527A (zh) | 2015-04-06 | 2018-02-16 | 托马斯杰斐逊大学 | 植入式生命体征传感器 |
| US10674944B2 (en) | 2015-05-14 | 2020-06-09 | Abbott Diabetes Care Inc. | Compact medical device inserters and related systems and methods |
| US10213139B2 (en) | 2015-05-14 | 2019-02-26 | Abbott Diabetes Care Inc. | Systems, devices, and methods for assembling an applicator and sensor control device |
| US10716500B2 (en) | 2015-06-29 | 2020-07-21 | Cardiac Pacemakers, Inc. | Systems and methods for normalization of chemical sensor data based on fluid state changes |
| AU2016291569B2 (en) | 2015-07-10 | 2021-07-08 | Abbott Diabetes Care Inc. | System, device and method of dynamic glucose profile response to physiological parameters |
| US11219392B2 (en) * | 2015-08-31 | 2022-01-11 | Trustees Of Tufts College | Vascular oximetry system |
| DK3377878T3 (da) * | 2015-11-18 | 2020-03-02 | Radiometer Medical Aps | Optisk sensor til detektering af frit hæmoglobin i en helblods prøve |
| US10716896B2 (en) | 2015-11-24 | 2020-07-21 | Insulet Corporation | Wearable automated medication delivery system |
| WO2017091584A1 (en) | 2015-11-25 | 2017-06-01 | Insulet Corporation | Wearable medication delivery device |
| US10275573B2 (en) | 2016-01-13 | 2019-04-30 | Bigfoot Biomedical, Inc. | User interface for diabetes management system |
| HK1256995A1 (zh) | 2016-01-14 | 2019-10-11 | Bigfoot Biomedical, Inc. | 药物输送设备、系统和方法中的阻塞解决方案 |
| CN112933333B (zh) | 2016-01-14 | 2023-03-28 | 比格福特生物医药公司 | 调整胰岛素输送速率 |
| RU2730366C2 (ru) * | 2016-02-04 | 2020-08-21 | Нова Биомедикэл Корпорэйшн | Аналитическая система и способ для определения параметров гемоглобина в цельной крови |
| US20170238804A1 (en) * | 2016-02-22 | 2017-08-24 | Memiray Inc. | Systems for continuous and non-continuous in-vivo spectroscopy and methods therefor |
| US10871487B2 (en) | 2016-04-20 | 2020-12-22 | Glusense Ltd. | FRET-based glucose-detection molecules |
| US12383166B2 (en) | 2016-05-23 | 2025-08-12 | Insulet Corporation | Insulin delivery system and methods with risk-based set points |
| WO2018049412A1 (en) | 2016-09-12 | 2018-03-15 | Graftworx, Inc. | Wearable device with multimodal diagnostics |
| US10765807B2 (en) | 2016-09-23 | 2020-09-08 | Insulet Corporation | Fluid delivery device with sensor |
| US10041881B2 (en) * | 2016-11-22 | 2018-08-07 | Airware, Inc. | NDIR glucose detection in liquids |
| AU2017376111B2 (en) | 2016-12-12 | 2023-02-02 | Bigfoot Biomedical, Inc. | Alarms and alerts for medication delivery devices and related systems and methods |
| EP3563119B1 (en) | 2016-12-29 | 2021-10-20 | Intuitive Surgical Operations, Inc. | Methods and apparatus for determining shape parameter(s) using a sensing fiber having a single core with multiple light propagating modes |
| US10881793B2 (en) | 2017-01-13 | 2021-01-05 | Bigfoot Biomedical, Inc. | System and method for adjusting insulin delivery |
| WO2018132723A1 (en) | 2017-01-13 | 2018-07-19 | Mazlish Bryan | Insulin delivery methods, systems and devices |
| US10500334B2 (en) | 2017-01-13 | 2019-12-10 | Bigfoot Biomedical, Inc. | System and method for adjusting insulin delivery |
| US10758675B2 (en) | 2017-01-13 | 2020-09-01 | Bigfoot Biomedical, Inc. | System and method for adjusting insulin delivery |
| EP3568859B1 (en) | 2017-01-13 | 2025-12-10 | Insulet Corporation | Insulin delivery methods, systems and devices |
| EP3570735A4 (en) | 2017-01-23 | 2020-10-21 | Abbott Diabetes Care Inc. | SYSTEMS, DEVICES AND METHODS FOR INSERTING ANALYTE SENSOR |
| WO2018156548A1 (en) | 2017-02-22 | 2018-08-30 | Insulet Corporation | Needle insertion mechanisms for drug containers |
| EP3600014B1 (en) | 2017-03-21 | 2025-07-30 | Abbott Diabetes Care Inc. | Devices and system for providing diabetic condition diagnosis |
| US10413658B2 (en) | 2017-03-31 | 2019-09-17 | Capillary Biomedical, Inc. | Helical insertion infusion device |
| CN108968976B (zh) | 2017-05-31 | 2022-09-13 | 心脏起搏器股份公司 | 具有化学传感器的植入式医疗设备 |
| WO2019023093A1 (en) | 2017-07-26 | 2019-01-31 | Cardiac Pacemakers, Inc. | SYSTEMS AND METHODS FOR POSTURE DISAMBIGULATION |
| CN109381195B (zh) | 2017-08-10 | 2023-01-10 | 心脏起搏器股份公司 | 包括电解质传感器融合的系统和方法 |
| CN109419515B (zh) | 2017-08-23 | 2023-03-24 | 心脏起搏器股份公司 | 具有分级激活的可植入化学传感器 |
| US11013436B2 (en) | 2017-09-06 | 2021-05-25 | Medtronic, Inc. | Marker monitoring via a medical device |
| US10898656B2 (en) | 2017-09-26 | 2021-01-26 | Insulet Corporation | Needle mechanism module for drug delivery device |
| US11331022B2 (en) | 2017-10-24 | 2022-05-17 | Dexcom, Inc. | Pre-connected analyte sensors |
| EP3700416B1 (en) | 2017-10-24 | 2024-06-26 | Dexcom, Inc. | Pre-connected analyte sensors |
| US11147931B2 (en) | 2017-11-17 | 2021-10-19 | Insulet Corporation | Drug delivery device with air and backflow elimination |
| CN109864746B (zh) | 2017-12-01 | 2023-09-29 | 心脏起搏器股份公司 | 用于医学装置的多模式分析物传感器 |
| CN109864747B (zh) | 2017-12-05 | 2023-08-25 | 心脏起搏器股份公司 | 多模式分析物传感器光电子接口 |
| USD928199S1 (en) | 2018-04-02 | 2021-08-17 | Bigfoot Biomedical, Inc. | Medication delivery device with icons |
| CN112236826B (zh) | 2018-05-04 | 2024-08-13 | 英赛罗公司 | 基于控制算法的药物输送系统的安全约束 |
| US11241532B2 (en) | 2018-08-29 | 2022-02-08 | Insulet Corporation | Drug delivery system with sensor having optimized communication and infusion site |
| AU2019347755B2 (en) | 2018-09-28 | 2023-02-02 | Insulet Corporation | Activity mode for artificial pancreas system |
| US11565039B2 (en) | 2018-10-11 | 2023-01-31 | Insulet Corporation | Event detection for drug delivery system |
| EP3877018A4 (en) | 2018-11-08 | 2022-08-10 | Capillary Biomedical, Inc. | Linear insertion device with rotational drive |
| USD920343S1 (en) | 2019-01-09 | 2021-05-25 | Bigfoot Biomedical, Inc. | Display screen or portion thereof with graphical user interface associated with insulin delivery |
| USD1002852S1 (en) | 2019-06-06 | 2023-10-24 | Abbott Diabetes Care Inc. | Analyte sensor device |
| US11801344B2 (en) | 2019-09-13 | 2023-10-31 | Insulet Corporation | Blood glucose rate of change modulation of meal and correction insulin bolus quantity |
| US11935637B2 (en) | 2019-09-27 | 2024-03-19 | Insulet Corporation | Onboarding and total daily insulin adaptivity |
| JP7716395B2 (ja) * | 2019-10-16 | 2025-07-31 | ヴィース・センター・フォー・バイオ・アンド・ニューロ・エンジニアリング | 埋込型システムの光通信 |
| US11957875B2 (en) | 2019-12-06 | 2024-04-16 | Insulet Corporation | Techniques and devices providing adaptivity and personalization in diabetes treatment |
| US11833329B2 (en) | 2019-12-20 | 2023-12-05 | Insulet Corporation | Techniques for improved automatic drug delivery performance using delivery tendencies from past delivery history and use patterns |
| EP4088286A1 (en) | 2020-01-06 | 2022-11-16 | Insulet Corporation | Prediction of meal and/or exercise events based on persistent residuals |
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| US11551802B2 (en) | 2020-02-11 | 2023-01-10 | Insulet Corporation | Early meal detection and calorie intake detection |
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| US11547800B2 (en) | 2020-02-12 | 2023-01-10 | Insulet Corporation | User parameter dependent cost function for personalized reduction of hypoglycemia and/or hyperglycemia in a closed loop artificial pancreas system |
| US11324889B2 (en) | 2020-02-14 | 2022-05-10 | Insulet Corporation | Compensation for missing readings from a glucose monitor in an automated insulin delivery system |
| US12495994B2 (en) | 2020-02-20 | 2025-12-16 | Insulet Corporation | Meal bolus subcategories in model based insulin therapy |
| US11607493B2 (en) | 2020-04-06 | 2023-03-21 | Insulet Corporation | Initial total daily insulin setting for user onboarding |
| WO2022020197A1 (en) | 2020-07-22 | 2022-01-27 | Insulet Corporation | Open-loop insulin delivery basal parameters based on insulin delivery records |
| US11684716B2 (en) | 2020-07-31 | 2023-06-27 | Insulet Corporation | Techniques to reduce risk of occlusions in drug delivery systems |
| WO2022047199A1 (en) | 2020-08-28 | 2022-03-03 | Capillary Biomedical, Inc. | Insulin infusion set |
| MY192294A (en) | 2020-08-31 | 2022-08-17 | Abbott Diabetes Care Inc | Systems, devices, and methods for analyte sensor insertion |
| US11579076B2 (en) | 2020-09-25 | 2023-02-14 | Samsung Electronics Co., Ltd. | Method and apparatus for correcting error of optical sensor, apparatus for estimating bio-information |
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| USD999913S1 (en) | 2020-12-21 | 2023-09-26 | Abbott Diabetes Care Inc | Analyte sensor inserter |
| US11160925B1 (en) | 2021-01-29 | 2021-11-02 | Insulet Corporation | Automatic drug delivery system for delivery of a GLP-1 therapeutic |
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| US11904140B2 (en) | 2021-03-10 | 2024-02-20 | Insulet Corporation | Adaptable asymmetric medicament cost component in a control system for medicament delivery |
| WO2022251642A1 (en) | 2021-05-28 | 2022-12-01 | Insulet Corporation | Spring-based status sensors |
| US12496398B2 (en) | 2021-05-28 | 2025-12-16 | Insulet Corporation | Threshold based automatic glucose control response |
| EP4101482A1 (en) | 2021-06-07 | 2022-12-14 | Insulet Corporation | Exercise safety prediction based on physiological conditions |
| EP4409581A1 (en) | 2021-09-27 | 2024-08-07 | Insulet Corporation | Techniques enabling adaptation of parameters in aid systems by user input |
| US11439754B1 (en) | 2021-12-01 | 2022-09-13 | Insulet Corporation | Optimizing embedded formulations for drug delivery |
| GB202212043D0 (en) * | 2022-08-18 | 2022-10-05 | Univ Of Lancaster | Glucose concentration measuring device |
| KR20250129777A (ko) | 2023-01-06 | 2025-08-29 | 인슐렛 코포레이션 | 후속 자동 안전 제약 완화를 갖는 자동으로 또는 수동으로 개시되는 음식 볼러스 전달 |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3837339A (en) * | 1972-02-03 | 1974-09-24 | Whittaker Corp | Blood glucose level monitoring-alarm system and method therefor |
| US4013074A (en) * | 1974-06-21 | 1977-03-22 | Siposs George G | Implantable medication-dispensing device |
| US4073292A (en) * | 1976-10-29 | 1978-02-14 | William Edelman | Control apparatus for the automatic treatment of diabetes |
| US4398908A (en) * | 1980-11-28 | 1983-08-16 | Siposs George G | Insulin delivery system |
| US4435173A (en) * | 1982-03-05 | 1984-03-06 | Delta Medical Industries | Variable rate syringe pump for insulin delivery |
| US4621643A (en) * | 1982-09-02 | 1986-11-11 | Nellcor Incorporated | Calibrated optical oximeter probe |
| US4679562A (en) * | 1983-02-16 | 1987-07-14 | Cardiac Pacemakers, Inc. | Glucose sensor |
| IT1170375B (it) * | 1983-04-19 | 1987-06-03 | Giuseppe Bombardieri | Apparecchio che infonde insulina o glucosio nel soggetto diabetico sulla base di determinazioni di concentrazioni di glucosio ottenute senza bisogno di prelievi del sangue del paziente |
| US4538616A (en) * | 1983-07-25 | 1985-09-03 | Robert Rogoff | Blood sugar level sensing and monitoring transducer |
| US4704029A (en) | 1985-12-26 | 1987-11-03 | Research Corporation | Blood glucose monitor |
| EP0249681B1 (de) * | 1986-06-16 | 1990-12-27 | Siemens Aktiengesellschaft | Messvorrichtung zur intrakardialen Erfassung der Blutsauerstoffsättigung |
| US4807629A (en) * | 1986-08-15 | 1989-02-28 | Medtronic, Inc. | Oxygen sensing pacemaker |
| US4865038A (en) * | 1986-10-09 | 1989-09-12 | Novametrix Medical Systems, Inc. | Sensor appliance for non-invasive monitoring |
| US4825879A (en) * | 1987-10-08 | 1989-05-02 | Critkon, Inc. | Pulse oximeter sensor |
| US4890621A (en) * | 1988-01-19 | 1990-01-02 | Northstar Research Institute, Ltd. | Continuous glucose monitoring and a system utilized therefor |
| US4822336A (en) * | 1988-03-04 | 1989-04-18 | Ditraglia John | Blood glucose level sensing |
| CA1327838C (fr) * | 1988-06-13 | 1994-03-15 | Fred Zacouto | Dispositif implantable de protection contre les affections liees a la coagulation sanguine |
| DE58903504D1 (de) * | 1988-07-19 | 1993-03-25 | Siemens Ag | Verfahren zur messung der konzentration optisch aktiver substanzen und anordnung zur durchfuehrung des verfahrens. |
| JPH02164341A (ja) * | 1988-12-19 | 1990-06-25 | Nippon Koden Corp | ヘモグロビン濃度測定装置 |
| US5204532A (en) * | 1989-01-19 | 1993-04-20 | Futrex, Inc. | Method for providing general calibration for near infrared instruments for measurement of blood glucose |
| US4975581A (en) * | 1989-06-21 | 1990-12-04 | University Of New Mexico | Method of and apparatus for determining the similarity of a biological analyte from a model constructed from known biological fluids |
| US4979509A (en) * | 1989-07-19 | 1990-12-25 | Northstar Research Institute, Ltd. | Continuous glucose monitoring and a system utilized therefor |
| US5101814A (en) * | 1989-08-11 | 1992-04-07 | Palti Yoram Prof | System for monitoring and controlling blood glucose |
| US5190041A (en) * | 1989-08-11 | 1993-03-02 | Palti Yoram Prof | System for monitoring and controlling blood glucose |
| US4996419A (en) * | 1989-12-26 | 1991-02-26 | United Technologies Corporation | Distributed multiplexed optical fiber Bragg grating sensor arrangeement |
| US5054487A (en) * | 1990-02-02 | 1991-10-08 | Boston Advanced Technologies, Inc. | Laser systems for material analysis based on reflectance ratio detection |
| US5115133A (en) * | 1990-04-19 | 1992-05-19 | Inomet, Inc. | Testing of body fluid constituents through measuring light reflected from tympanic membrane |
| JPH0415046A (ja) * | 1990-05-10 | 1992-01-20 | Kowa Co | 血液循環動態の測定方法 |
| US5361759A (en) * | 1990-07-04 | 1994-11-08 | Charing Cross & Westminster Medical School | Meconium monitoring system |
| US5209231A (en) | 1990-11-02 | 1993-05-11 | University Of Connecticut | Optical glucose sensor apparatus and method |
| SE9100008D0 (sv) * | 1990-12-28 | 1990-12-28 | Aake Oeberg | Saett och sensor foer detektering av specifika parametrar hos cirkulerande blod inuti en levande organism |
| AT397458B (de) | 1992-09-25 | 1994-04-25 | Avl Verbrennungskraft Messtech | Sensoranordnung |
| JP3313841B2 (ja) * | 1993-09-24 | 2002-08-12 | 興和株式会社 | 血流測定装置 |
| US5459801A (en) * | 1993-10-29 | 1995-10-17 | Rutgers University | Coupler used to fabricate add-drop devices, dispersion compensators, amplifiers, oscillators, superluminescent devices, and communications systems |
| US5428635A (en) * | 1994-01-11 | 1995-06-27 | American Biogenetic Sciences, Inc. | Multi-wavelength tunable laser |
| US5457760A (en) * | 1994-05-06 | 1995-10-10 | At&T Ipm Corp. | Wavelength division optical multiplexing elements |
| US5474552A (en) * | 1994-06-27 | 1995-12-12 | Cb-Carmel Biotechnology Ltd. | Implantable drug delivery pump |
| US5589684A (en) * | 1994-06-28 | 1996-12-31 | Sdl, Inc. | Multiple diode lasers stabilized with a fiber grating |
| US5995860A (en) * | 1995-07-06 | 1999-11-30 | Thomas Jefferson University | Implantable sensor and system for measurement and control of blood constituent levels |
| US5627848A (en) * | 1995-09-05 | 1997-05-06 | Imra America, Inc. | Apparatus for producing femtosecond and picosecond pulses from modelocked fiber lasers cladding pumped with broad area diode laser arrays |
| US5608825A (en) * | 1996-02-01 | 1997-03-04 | Jds Fitel Inc. | Multi-wavelength filtering device using optical fiber Bragg grating |
-
1997
- 1997-07-08 IL IL12721397A patent/IL127213A/xx not_active IP Right Cessation
- 1997-07-08 WO PCT/US1997/011832 patent/WO1998001071A1/en not_active Ceased
- 1997-07-08 EP EP97932530A patent/EP0923335B1/en not_active Expired - Lifetime
- 1997-07-08 AU AU35965/97A patent/AU3596597A/en not_active Abandoned
- 1997-07-08 JP JP10505318A patent/JP2000515778A/ja not_active Ceased
- 1997-07-08 CA CA002259254A patent/CA2259254C/en not_active Expired - Lifetime
-
1998
- 1998-04-03 US US09/054,806 patent/US6049727A/en not_active Expired - Lifetime
-
2007
- 2007-02-15 JP JP2007034990A patent/JP2007175514A/ja active Pending
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8506550B2 (en) | 2001-09-07 | 2013-08-13 | Medtronic Minimed, Inc. | Method and system for non-vascular sensor implantation |
| JP2005525139A (ja) * | 2001-10-23 | 2005-08-25 | メドトロニック ミニメド インコーポレイテッド | 非血管センサ埋め込みのための方法およびシステム |
| US8465466B2 (en) | 2001-10-23 | 2013-06-18 | Medtronic Minimed, Inc | Method and system for non-vascular sensor implantation |
| JP2006500170A (ja) * | 2002-09-27 | 2006-01-05 | メドトロニック ミニメド インコーポレイテッド | 埋込可能型センサ方法及びシステム |
| US7736309B2 (en) | 2002-09-27 | 2010-06-15 | Medtronic Minimed, Inc. | Implantable sensor method and system |
| JP2004358244A (ja) * | 2003-05-30 | 2004-12-24 | Siemens Ag | 生物の代謝過程における少なくとも１つの物質の検出方法および装置 |
| JP2008191149A (ja) * | 2007-02-05 | 2008-08-21 | Palo Alto Research Center Inc | 植設用光学キャビティ構造 |
| JP2013533769A (ja) * | 2010-06-22 | 2013-08-29 | センスペック・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 測定媒体の成分または特性、特に生理的血液値を特定およびモニタするための装置ならびに方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO1998001071A1 (en) | 1998-01-15 |
| EP0923335A1 (en) | 1999-06-23 |
| AU3596597A (en) | 1998-02-02 |
| EP0923335B1 (en) | 2006-08-23 |
| US6049727A (en) | 2000-04-11 |
| EP0923335A4 (en) | 2000-03-22 |
| IL127213A (en) | 2003-09-17 |
| CA2259254A1 (en) | 1998-01-15 |
| IL127213A0 (en) | 1999-09-22 |
| CA2259254C (en) | 2008-02-19 |
| JP2007175514A (ja) | 2007-07-12 |
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