JP2000515370A5 - - Google Patents

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Publication number
JP2000515370A5
JP2000515370A5 JP1998505608A JP50560898A JP2000515370A5 JP 2000515370 A5 JP2000515370 A5 JP 2000515370A5 JP 1998505608 A JP1998505608 A JP 1998505608A JP 50560898 A JP50560898 A JP 50560898A JP 2000515370 A5 JP2000515370 A5 JP 2000515370A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1998505608A
Other languages
English (en)
Japanese (ja)
Other versions
JP4177457B2 (ja
JP2000515370A (ja
Filing date
Publication date
Priority claimed from GBGB9614871.3A external-priority patent/GB9614871D0/en
Application filed filed Critical
Publication of JP2000515370A publication Critical patent/JP2000515370A/ja
Publication of JP2000515370A5 publication Critical patent/JP2000515370A5/ja
Application granted granted Critical
Publication of JP4177457B2 publication Critical patent/JP4177457B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP50560898A 1996-07-15 1997-07-08 膜結合剤と可溶性ペプヂド性化合物の結合体 Expired - Fee Related JP4177457B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9614871.3A GB9614871D0 (en) 1996-07-15 1996-07-15 Compounds
GB9614871.3 1996-07-15
PCT/EP1997/003715 WO1998002454A2 (en) 1996-07-15 1997-07-08 Conjugates of soluble peptidic compounds with membrane-binding agents

Publications (3)

Publication Number Publication Date
JP2000515370A JP2000515370A (ja) 2000-11-21
JP2000515370A5 true JP2000515370A5 (enExample) 2005-07-14
JP4177457B2 JP4177457B2 (ja) 2008-11-05

Family

ID=10796956

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50560898A Expired - Fee Related JP4177457B2 (ja) 1996-07-15 1997-07-08 膜結合剤と可溶性ペプヂド性化合物の結合体

Country Status (17)

Country Link
US (3) US6713606B1 (enExample)
EP (1) EP0912730B1 (enExample)
JP (1) JP4177457B2 (enExample)
AR (1) AR007737A1 (enExample)
AT (1) ATE419345T1 (enExample)
AU (1) AU732725B2 (enExample)
CA (1) CA2260288A1 (enExample)
CO (1) CO4750673A1 (enExample)
DE (1) DE69739186D1 (enExample)
DK (1) DK0912730T3 (enExample)
ES (1) ES2321245T3 (enExample)
GB (1) GB9614871D0 (enExample)
IL (3) IL128034A0 (enExample)
NZ (1) NZ333722A (enExample)
TW (1) TW538048B (enExample)
WO (1) WO1998002454A2 (enExample)
ZA (1) ZA976216B (enExample)

Families Citing this family (38)

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GB9614871D0 (en) * 1996-07-15 1996-09-04 Smithkline Beecham Plc Compounds
US6210707B1 (en) 1996-11-12 2001-04-03 The Regents Of The University Of California Methods of forming protein-linked lipidic microparticles, and compositions thereof
GB9704519D0 (en) * 1997-03-05 1997-04-23 Smithkline Beecham Plc Compounds
WO1999028454A1 (en) 1997-11-28 1999-06-10 Roche Diagnostics Gmbh An active hedgehog-protein-mutant, a process for its preparation and its use for pharmaceutical purposes
ES2252886T3 (es) 1998-04-30 2006-05-16 Curis, Inc. Conjugado de proteinas de erizo activo, proceso para su produccion y uso.
GB9815505D0 (en) * 1998-07-16 1998-09-16 Adprotech Plc Polypeptide derivatives
GB9905503D0 (en) * 1999-03-10 1999-05-05 Adprotech Plc Novel compound formulations and methods of delivery
GB0016811D0 (en) * 2000-07-07 2000-08-30 Adprotech Ltd Lipid rafts
GB0026924D0 (en) 2000-11-03 2000-12-20 Univ Cambridge Tech Antibacterial agents
GB0117193D0 (en) * 2001-07-13 2001-09-05 Adprotech Ltd Protein modification reagents
GB0123262D0 (en) * 2001-09-27 2001-11-21 Adprotech Ltd Polymeric compounds
GB0220936D0 (en) * 2002-09-05 2002-10-23 Adprotech Ltd Modified therapeutic agents
FR2854897B1 (fr) * 2003-05-12 2007-05-04 Sederma Sa Compositions cosmetiques ou dermopharmaceutiques pour reduire les signes du vieillissement cutane.
US7858108B2 (en) * 2003-10-21 2010-12-28 Richard Nagler Elutable surface coating
US8454963B2 (en) * 2003-11-13 2013-06-04 Musc Foundation For Research Development Tissue targeted complement modulators
US8124097B2 (en) * 2004-01-21 2012-02-28 Case Western Reserve University Hybrid and chimeric polypeptides that regulate activation of complement
WO2005115430A1 (en) 2004-05-27 2005-12-08 Gropep Limited Treatment of inflammatory airway disease
JP2009508937A (ja) * 2005-09-22 2009-03-05 イエダ リサーチ アンド デベロップメント カンパニー リミテッド T細胞免疫を調節するためのジアステレオマーペプチド
DE602007010431D1 (de) 2006-03-09 2010-12-23 Cambridge Entpr Ltd Neuartige antibiotische zusammensetzungen
EP2083841B1 (en) 2006-10-20 2013-11-20 Celldex Therapeutics, Inc. SOLUBLE COMPLEMENT RECEPTOR TYPE I (sCR1) PROTEIN FOR USE IN THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION AND OTHER DISEASES OF THE EYE
US8748371B2 (en) * 2007-02-28 2014-06-10 Yeda Research And Development Co. Ltd. Nuclear targeting sequences
US8937046B2 (en) 2008-09-22 2015-01-20 The Regents Of The University Of Colorado, A Body Corporate Modulating the alternative complement pathway
EA021852B1 (ru) * 2009-02-20 2015-09-30 Ипсен Фарма С.А.С. Аналоги нейропептида y с заменой на пролин в положении 34
CN102395377B (zh) * 2009-04-16 2016-10-19 海德堡吕布莱希特-卡尔斯大学 增强肌肉功能的肽
GB0915519D0 (en) 2009-09-04 2009-10-07 King S College London Ntithrombotic compounds
WO2011050334A1 (en) * 2009-10-22 2011-04-28 Yong Zhu Compositions and methods for re-programming cells without genetic modification for treatment of obesity and related diseases
CN107661491A (zh) 2010-09-15 2018-02-06 赛尔戴克斯治疗公司 用可溶性I型补体受体(sCR1)治疗慢性肾病
BR112013010098A2 (pt) 2010-10-27 2017-06-13 Celldex Therapeutics Inc método para melhorar a função de transplante usando um receptor do complemento solúvel tipo i (scr1)
CA2857168C (en) * 2011-12-01 2020-10-27 Protevobio, Inc. Protein inhibitors to complement and vegf pathways and methods of use thereof
WO2015017316A2 (en) * 2013-08-01 2015-02-05 Abbott Nicholas L Methods and compositions for modifying mucous membranes
WO2015040609A1 (en) 2013-09-17 2015-03-26 Yeda Research And Development Co. Ltd. Erk-derived peptides and uses thereof
GB201402267D0 (en) 2014-02-10 2014-03-26 Cambridge Entpr Ltd Antibacterial agents
GB2583560A (en) 2018-12-11 2020-11-04 Admirx Inc Fusion protein constructs for complement associated disease
CN110240656A (zh) * 2019-04-24 2019-09-17 中山大学附属第三医院 一种融合蛋白及其制备方法与应用
CN110551177A (zh) * 2019-08-29 2019-12-10 安徽瑞达健康产业有限公司 多肽、多肽衍生物、多肽-抗体复合物及制备、应用
GB201913804D0 (en) 2019-09-25 2019-11-06 Prostate Cancer Res Centre Fusion polypeptides
WO2024092160A2 (en) * 2022-10-26 2024-05-02 Flagship Pioneering Innovations Vii, Llc Bifunctional proteases and uses thereof
GB202304385D0 (en) 2023-03-24 2023-05-10 Prostate Cancer Res Combinatorial IL-15 therapy

Family Cites Families (21)

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Publication number Priority date Publication date Assignee Title
EP0109653A3 (en) 1982-11-17 1986-01-29 Otsuka Pharmaceutical Co., Ltd. Process for preparing urokinase complex
EP0114787B1 (de) * 1983-01-25 1991-09-25 Ciba-Geigy Ag Neue Peptidderivate
GB8334498D0 (en) 1983-12-24 1984-02-01 Beecham Group Plc Compounds
GB8400653D0 (en) 1984-01-11 1984-02-15 Beecham Group Plc Conjugates
NZ215660A (en) 1985-04-04 1990-03-27 Beecham Group Plc Tissue plasminogen activator modified in the growth factor domain
US5374548A (en) 1986-05-02 1994-12-20 Genentech, Inc. Methods and compositions for the attachment of proteins to liposomes using a glycophospholipid anchor
JP2573007B2 (ja) * 1987-12-28 1997-01-16 株式会社成和化成 修飾された動物毛粉末
US5256642A (en) 1988-04-01 1993-10-26 The Johns Hopkins University Compositions of soluble complement receptor 1 (CR1) and a thrombolytic agent, and the methods of use thereof
US5582968A (en) * 1990-02-16 1996-12-10 United Biomedical, Inc. Branched hybrid and cluster peptides effective in diagnosing and detecting non-A, non-B hepatitis
US6458360B1 (en) 1990-04-25 2002-10-01 The Johns Hopkins University Soluble complement regulatory molecules
US5326700A (en) 1990-11-06 1994-07-05 Eli Lilly And Company DNA sequences encoding t-PA derivatives with cleavable sites
WO1993022343A1 (en) * 1992-05-01 1993-11-11 The Rockfeller University Multiple antigen peptide system having adjuvant properties and vaccines prepared therefrom
EP0649468B1 (en) * 1992-06-24 2000-03-15 AdProTech plc Soluble cr1 derivatives
US5456909A (en) 1992-08-07 1995-10-10 T Cell Sciences, Inc. Glycoform fractions of recombinant soluble complement receptor 1 (sCR1) having extended half-lives in vivo
US5856300A (en) * 1994-05-12 1999-01-05 T Cell Sciences, Inc. Compositions comprising complement related proteins and carbohydrates, and methods for producing and using said compositions
DK0730608T3 (da) * 1993-05-17 2002-07-22 Avant Immunotherapeutics Inc Præparater omfattende komplementrelaterede proteiner og carbohydrater og fremgangsmåder til fremstilling og anvendelse af præparaterne
EP0750458B1 (en) * 1994-03-03 2003-08-27 Alexion Pharmaceuticals, Inc. Terminal complement inhibitor fusion genes and proteins
GB9614871D0 (en) * 1996-07-15 1996-09-04 Smithkline Beecham Plc Compounds
US5776689A (en) 1996-07-19 1998-07-07 The Regents Of The University Of California Protein recruitment system
JP2002526775A (ja) 1998-10-01 2002-08-20 テイテイエブスキ,アレクセイ・ウラデイミロビチ GDNFについての新規Ret非依存性シグナリング経路
GB0220936D0 (en) * 2002-09-05 2002-10-23 Adprotech Ltd Modified therapeutic agents

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