JP2000513230A5 - - Google Patents

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Publication number
JP2000513230A5
JP2000513230A5 JP1998503679A JP50367998A JP2000513230A5 JP 2000513230 A5 JP2000513230 A5 JP 2000513230A5 JP 1998503679 A JP1998503679 A JP 1998503679A JP 50367998 A JP50367998 A JP 50367998A JP 2000513230 A5 JP2000513230 A5 JP 2000513230A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP1998503679A
Other languages
English (en)
Japanese (ja)
Other versions
JP2000513230A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CA1997/000454 external-priority patent/WO1998000532A2/en
Publication of JP2000513230A publication Critical patent/JP2000513230A/ja
Publication of JP2000513230A5 publication Critical patent/JP2000513230A5/ja
Ceased legal-status Critical Current

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JP10503679A 1996-07-01 1997-06-30 ハウスキーピング遺伝子の非翻訳領域由来のオリゴヌクレオチドおよび細胞増殖を調節するためのその使用方法 Ceased JP2000513230A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2115296P 1996-07-01 1996-07-01
US60/021,152 1996-07-01
PCT/CA1997/000454 WO1998000532A2 (en) 1996-07-01 1997-06-30 Oligonucleotides from the untranslated regions of ribonucleotide reductase and their use to modulate cell growth

Publications (2)

Publication Number Publication Date
JP2000513230A JP2000513230A (ja) 2000-10-10
JP2000513230A5 true JP2000513230A5 (enExample) 2005-05-12

Family

ID=21802643

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10503679A Ceased JP2000513230A (ja) 1996-07-01 1997-06-30 ハウスキーピング遺伝子の非翻訳領域由来のオリゴヌクレオチドおよび細胞増殖を調節するためのその使用方法

Country Status (6)

Country Link
US (2) US7223849B1 (enExample)
EP (1) EP0954574A2 (enExample)
JP (1) JP2000513230A (enExample)
AU (1) AU3249897A (enExample)
CA (1) CA2259123C (enExample)
WO (1) WO1998000532A2 (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0954574A2 (en) 1996-07-01 1999-11-10 Jim A. Wright Oligonucleotides from the untranslated regions of housekeeping genes and methods of using same to modulate cell growth
US6593305B1 (en) 1996-08-02 2003-07-15 Genesense Technologies Inc. Antitumor antisense sequences directed against R1 and R2 components of ribonucleotide reductase
CN1256632A (zh) 1997-03-19 2000-06-14 吉倪塞思技术公司 利用核糖核苷酸还原酶r1抑制恶性肿瘤
DK2284266T3 (da) 2002-11-14 2014-01-13 Thermo Fisher Scient Biosciences Inc sIRNA-MOLEKYLE MOD TP53
WO2006006948A2 (en) 2002-11-14 2006-01-19 Dharmacon, Inc. METHODS AND COMPOSITIONS FOR SELECTING siRNA OF IMPROVED FUNCTIONALITY
US9228186B2 (en) 2002-11-14 2016-01-05 Thermo Fisher Scientific Inc. Methods and compositions for selecting siRNA of improved functionality
US7691998B2 (en) 2002-11-14 2010-04-06 Dharmacon, Inc. siRNA targeting nucleoporin 62kDa (Nup62)
US9719094B2 (en) 2002-11-14 2017-08-01 Thermo Fisher Scientific Inc. RNAi targeting SEC61G
US10011836B2 (en) 2002-11-14 2018-07-03 Thermo Fisher Scientific Inc. Methods and compositions for selecting siRNA of improved functionality
US9879266B2 (en) 2002-11-14 2018-01-30 Thermo Fisher Scientific Inc. Methods and compositions for selecting siRNA of improved functionality
US8198427B1 (en) 2002-11-14 2012-06-12 Dharmacon, Inc. SiRNA targeting catenin, beta-1 (CTNNB1)
US7612196B2 (en) 2002-11-14 2009-11-03 Dharmacon, Inc. siRNA targeting cyclin-dependent kinase inhibitor 1B (p27, Kip1) (CDKN1B)
US7592442B2 (en) * 2002-11-14 2009-09-22 Dharmacon, Inc. siRNA targeting ribonucleotide reductase M2 polypeptide (RRM2 or RNR-R2)
US9719092B2 (en) 2002-11-14 2017-08-01 Thermo Fisher Scientific Inc. RNAi targeting CNTD2
US7951935B2 (en) 2002-11-14 2011-05-31 Dharmacon, Inc. siRNA targeting v-myc myelocytomatosis viral oncogene homolog (MYC)
US7619081B2 (en) 2002-11-14 2009-11-17 Dharmacon, Inc. siRNA targeting coatomer protein complex, subunit beta 2 (COPB2)
US9771586B2 (en) 2002-11-14 2017-09-26 Thermo Fisher Scientific Inc. RNAi targeting ZNF205
US7635770B2 (en) 2002-11-14 2009-12-22 Dharmacon, Inc. siRNA targeting protein kinase N-3 (PKN-3)
US9839649B2 (en) 2002-11-14 2017-12-12 Thermo Fisher Scientific Inc. Methods and compositions for selecting siRNA of improved functionality
US7977471B2 (en) 2002-11-14 2011-07-12 Dharmacon, Inc. siRNA targeting TNFα
WO2004070033A1 (en) 2003-02-10 2004-08-19 Genesense Technologies Inc. Antisense oligonucleotides directed to ribonucleotide reductase r2 and uses thereof in the treatment of cancer
AU2005203822A1 (en) * 2004-01-12 2005-07-21 Lorus Therapeutics Inc. Antisense oligonucleotides directed to ribonucleotide reductase R2 and uses thereof in combination therapies for the treatment of cancer
US7605250B2 (en) 2004-05-12 2009-10-20 Dharmacon, Inc. siRNA targeting cAMP-specific phosphodiesterase 4D

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4358535A (en) * 1980-12-08 1982-11-09 Board Of Regents Of The University Of Washington Specific DNA probes in diagnostic microbiology
US4873191A (en) 1981-06-12 1989-10-10 Ohio University Genetic transformation of zygotes
US4736866B1 (en) 1984-06-22 1988-04-12 Transgenic non-human mammals
ATE132266T1 (de) 1987-05-01 1996-01-15 Stratagene Inc Mutagenesetest durch verwendung von nicht menschlichen lebewesen, die test-dns-sequenzen enthalten
US5175385A (en) 1987-09-03 1992-12-29 Ohio University/Edison Animal Biotechnolgy Center Virus-resistant transgenic mice
US5221778A (en) 1988-08-24 1993-06-22 Yale University Multiplex gene regulation
US5175384A (en) 1988-12-05 1992-12-29 Genpharm International Transgenic mice depleted in mature t-cells and methods for making transgenic mice
US5175383A (en) 1989-02-17 1992-12-29 President And Fellows Of Harvard College Animal model for benign prostatic disease
CA1327869C (en) * 1989-02-17 1994-03-15 Yvan Guindon Ribonucleotide reductase inhibitors
US5464764A (en) 1989-08-22 1995-11-07 University Of Utah Research Foundation Positive-negative selection methods and vectors
US5225347A (en) 1989-09-25 1993-07-06 Innovir Laboratories, Inc. Therapeutic ribozyme compositions and expression vectors
US5614396A (en) 1990-06-14 1997-03-25 Baylor College Of Medicine Methods for the genetic modification of endogenous genes in animal cells by homologous recombination
US5387742A (en) 1990-06-15 1995-02-07 Scios Nova Inc. Transgenic mice displaying the amyloid-forming pathology of alzheimer's disease
US5288846A (en) 1990-10-19 1994-02-22 The General Hospital Corporation Cell specific gene regulators
JPH06509578A (ja) 1991-07-26 1994-10-27 ユニバーシティ・オブ・ロチェスター 悪性細胞利用による癌治療法
US5298422A (en) 1991-11-06 1994-03-29 Baylor College Of Medicine Myogenic vector systems
DK0620849T3 (da) 1992-01-07 2003-10-20 Elan Pharm Inc Transgene dyremodeller for Alzheimer's sygdom
US5360735A (en) 1992-01-08 1994-11-01 Synaptic Pharmaceutical Corporation DNA encoding a human 5-HT1F receptor, vectors, and host cells
AU3596593A (en) * 1992-02-19 1993-09-13 Baylor College Of Medicine Oligonucleotide modulation of cell growth
US5681747A (en) * 1992-03-16 1997-10-28 Isis Pharmaceuticals, Inc. Nucleic acid sequences encoding protein kinase C and antisense inhibition of expression thereof
EP0663952A4 (en) 1992-09-11 1997-06-11 Univ California Transgenic non-human animals having targeted lymphocyte transduction genes.
AU6490894A (en) * 1993-03-23 1994-10-11 Board Of Trustees Of The Leland Stanford Junior University Cellular regulation with riboregulators
WO1994023049A2 (en) 1993-04-02 1994-10-13 The Johns Hopkins University The introduction and expression of large genomic sequences in transgenic animals
US6664107B1 (en) 1993-05-26 2003-12-16 Ontario Cancer Institute, University Health Network CD45 disrupted nucleic acid
WO1995019369A1 (en) * 1994-01-14 1995-07-20 Vanderbilt University Method for detection and treatment of breast cancer
ES2173248T3 (es) * 1995-02-07 2002-10-16 Kyowa Hakko Kogyo Kk Anticuerpo monocional contra la subunidad r2 de la ribonucleotido reductasa.
EP0954574A2 (en) 1996-07-01 1999-11-10 Jim A. Wright Oligonucleotides from the untranslated regions of housekeeping genes and methods of using same to modulate cell growth
ES2256893T3 (es) * 1996-08-02 2006-07-16 Genesense Technologies Inc. Secuencias antisentido antitumorales dirigidas contra componentes r1 y r2 de la reductasa ribonucleica.

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