JP2000513230A5 - - Google Patents
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- Publication number
- JP2000513230A5 JP2000513230A5 JP1998503679A JP50367998A JP2000513230A5 JP 2000513230 A5 JP2000513230 A5 JP 2000513230A5 JP 1998503679 A JP1998503679 A JP 1998503679A JP 50367998 A JP50367998 A JP 50367998A JP 2000513230 A5 JP2000513230 A5 JP 2000513230A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2115296P | 1996-07-01 | 1996-07-01 | |
| US60/021,152 | 1996-07-01 | ||
| PCT/CA1997/000454 WO1998000532A2 (en) | 1996-07-01 | 1997-06-30 | Oligonucleotides from the untranslated regions of ribonucleotide reductase and their use to modulate cell growth |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2000513230A JP2000513230A (ja) | 2000-10-10 |
| JP2000513230A5 true JP2000513230A5 (enExample) | 2005-05-12 |
Family
ID=21802643
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP10503679A Ceased JP2000513230A (ja) | 1996-07-01 | 1997-06-30 | ハウスキーピング遺伝子の非翻訳領域由来のオリゴヌクレオチドおよび細胞増殖を調節するためのその使用方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US7223849B1 (enExample) |
| EP (1) | EP0954574A2 (enExample) |
| JP (1) | JP2000513230A (enExample) |
| AU (1) | AU3249897A (enExample) |
| CA (1) | CA2259123C (enExample) |
| WO (1) | WO1998000532A2 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7223849B1 (en) | 1996-07-01 | 2007-05-29 | Genesense Technologies Inc. | Oligonucleotides from the untranslated regions of housekeeping genes and methods of using same to modulate cell growth |
| US6593305B1 (en) | 1996-08-02 | 2003-07-15 | Genesense Technologies Inc. | Antitumor antisense sequences directed against R1 and R2 components of ribonucleotide reductase |
| DE69823813T2 (de) * | 1997-03-19 | 2005-06-30 | Genesense Technologies, Inc., Toronto | Malignitätsunterdrückung unter verwendung von ribonukleotidreduktase r1 |
| US9879266B2 (en) | 2002-11-14 | 2018-01-30 | Thermo Fisher Scientific Inc. | Methods and compositions for selecting siRNA of improved functionality |
| US9719094B2 (en) | 2002-11-14 | 2017-08-01 | Thermo Fisher Scientific Inc. | RNAi targeting SEC61G |
| US7635770B2 (en) | 2002-11-14 | 2009-12-22 | Dharmacon, Inc. | siRNA targeting protein kinase N-3 (PKN-3) |
| US7951935B2 (en) | 2002-11-14 | 2011-05-31 | Dharmacon, Inc. | siRNA targeting v-myc myelocytomatosis viral oncogene homolog (MYC) |
| US7691998B2 (en) | 2002-11-14 | 2010-04-06 | Dharmacon, Inc. | siRNA targeting nucleoporin 62kDa (Nup62) |
| US7592442B2 (en) * | 2002-11-14 | 2009-09-22 | Dharmacon, Inc. | siRNA targeting ribonucleotide reductase M2 polypeptide (RRM2 or RNR-R2) |
| EP2305813A3 (en) | 2002-11-14 | 2012-03-28 | Dharmacon, Inc. | Fuctional and hyperfunctional sirna |
| US9228186B2 (en) | 2002-11-14 | 2016-01-05 | Thermo Fisher Scientific Inc. | Methods and compositions for selecting siRNA of improved functionality |
| US7619081B2 (en) | 2002-11-14 | 2009-11-17 | Dharmacon, Inc. | siRNA targeting coatomer protein complex, subunit beta 2 (COPB2) |
| US7977471B2 (en) | 2002-11-14 | 2011-07-12 | Dharmacon, Inc. | siRNA targeting TNFα |
| US10011836B2 (en) | 2002-11-14 | 2018-07-03 | Thermo Fisher Scientific Inc. | Methods and compositions for selecting siRNA of improved functionality |
| WO2006006948A2 (en) | 2002-11-14 | 2006-01-19 | Dharmacon, Inc. | METHODS AND COMPOSITIONS FOR SELECTING siRNA OF IMPROVED FUNCTIONALITY |
| US9839649B2 (en) | 2002-11-14 | 2017-12-12 | Thermo Fisher Scientific Inc. | Methods and compositions for selecting siRNA of improved functionality |
| US7612196B2 (en) | 2002-11-14 | 2009-11-03 | Dharmacon, Inc. | siRNA targeting cyclin-dependent kinase inhibitor 1B (p27, Kip1) (CDKN1B) |
| US9771586B2 (en) | 2002-11-14 | 2017-09-26 | Thermo Fisher Scientific Inc. | RNAi targeting ZNF205 |
| US9719092B2 (en) | 2002-11-14 | 2017-08-01 | Thermo Fisher Scientific Inc. | RNAi targeting CNTD2 |
| US8198427B1 (en) | 2002-11-14 | 2012-06-12 | Dharmacon, Inc. | SiRNA targeting catenin, beta-1 (CTNNB1) |
| JP2006518344A (ja) | 2003-02-10 | 2006-08-10 | ジェネセンス テクノロジーズ インク | リボヌクレオチド還元酵素ｒ２を指向するアンチセンスオリゴヌクレオチドおよび癌の治療におけるこれらの使用 |
| EP1715896A4 (en) * | 2004-01-12 | 2009-01-07 | Lorus Therapeutics Inc | ANTISENSE OLIGONUCLEOTIDES DIRECTED AGAINST RIBONUCLEOTIDE REDUCTASE R2 AND USE THEREOF IN POLYTHERAPIES FOR THE TREATMENT OF CANCER |
| US7605250B2 (en) | 2004-05-12 | 2009-10-20 | Dharmacon, Inc. | siRNA targeting cAMP-specific phosphodiesterase 4D |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4358535A (en) * | 1980-12-08 | 1982-11-09 | Board Of Regents Of The University Of Washington | Specific DNA probes in diagnostic microbiology |
| US4873191A (en) | 1981-06-12 | 1989-10-10 | Ohio University | Genetic transformation of zygotes |
| US4736866B1 (en) | 1984-06-22 | 1988-04-12 | Transgenic non-human mammals | |
| EP0289121B1 (en) | 1987-05-01 | 1995-12-27 | Stratagene | Mutagenesis testing using transgenic non-human animals carrying test DNA sequences |
| US5175385A (en) | 1987-09-03 | 1992-12-29 | Ohio University/Edison Animal Biotechnolgy Center | Virus-resistant transgenic mice |
| US5221778A (en) | 1988-08-24 | 1993-06-22 | Yale University | Multiplex gene regulation |
| US5175384A (en) | 1988-12-05 | 1992-12-29 | Genpharm International | Transgenic mice depleted in mature t-cells and methods for making transgenic mice |
| US5175383A (en) | 1989-02-17 | 1992-12-29 | President And Fellows Of Harvard College | Animal model for benign prostatic disease |
| CA1327869C (en) * | 1989-02-17 | 1994-03-15 | Yvan Guindon | Ribonucleotide reductase inhibitors |
| US5464764A (en) | 1989-08-22 | 1995-11-07 | University Of Utah Research Foundation | Positive-negative selection methods and vectors |
| US5225347A (en) | 1989-09-25 | 1993-07-06 | Innovir Laboratories, Inc. | Therapeutic ribozyme compositions and expression vectors |
| US5614396A (en) | 1990-06-14 | 1997-03-25 | Baylor College Of Medicine | Methods for the genetic modification of endogenous genes in animal cells by homologous recombination |
| JPH06507782A (ja) | 1990-06-15 | 1994-09-08 | サイオス ノバ インコーポレイテッド | アルツハイマー病のアミロイド形成開症状を示すヒト以外の組換え哺乳動物 |
| US5288846A (en) | 1990-10-19 | 1994-02-22 | The General Hospital Corporation | Cell specific gene regulators |
| CA2113990A1 (en) | 1991-07-26 | 1993-02-18 | Frederick L. Moolten | Cancer therapy utilizing malignant cells |
| US5298422A (en) | 1991-11-06 | 1994-03-29 | Baylor College Of Medicine | Myogenic vector systems |
| DE69233109T2 (de) | 1992-01-07 | 2004-05-19 | Elan Pharmaceuticals, Inc., San Francisco | Transgene tiermodelle fur alzheimer-krankheit |
| US5360735A (en) | 1992-01-08 | 1994-11-01 | Synaptic Pharmaceutical Corporation | DNA encoding a human 5-HT1F receptor, vectors, and host cells |
| JP2731630B2 (ja) * | 1992-02-19 | 1998-03-25 | ベイラー・カレッジ・オブ・メディスン | 細胞増殖のオリゴヌクレオチドの変調 |
| US5681747A (en) | 1992-03-16 | 1997-10-28 | Isis Pharmaceuticals, Inc. | Nucleic acid sequences encoding protein kinase C and antisense inhibition of expression thereof |
| EP0663952A4 (en) | 1992-09-11 | 1997-06-11 | Univ California | TRANSGENIC ANIMALS HAVING TARGET LYMPHOCYTA TRANSDUCTION GENES. |
| EP0690869A1 (en) * | 1993-03-23 | 1996-01-10 | The Board Of Trustees Of The Leland Stanford Junior University | Cellular regulation with riboregulators |
| WO1994023049A2 (en) | 1993-04-02 | 1994-10-13 | The Johns Hopkins University | The introduction and expression of large genomic sequences in transgenic animals |
| US6664107B1 (en) | 1993-05-26 | 2003-12-16 | Ontario Cancer Institute, University Health Network | CD45 disrupted nucleic acid |
| WO1995019369A1 (en) * | 1994-01-14 | 1995-07-20 | Vanderbilt University | Method for detection and treatment of breast cancer |
| ATE216709T1 (de) * | 1995-02-07 | 2002-05-15 | Kyowa Hakko Kogyo Kk | Monoklonäler antikörper gegen die r2-untereinheit von ribonukleotid-reduktase |
| US7223849B1 (en) | 1996-07-01 | 2007-05-29 | Genesense Technologies Inc. | Oligonucleotides from the untranslated regions of housekeeping genes and methods of using same to modulate cell growth |
| CN1189562C (zh) * | 1996-08-02 | 2005-02-16 | 吉倪塞思技术公司 | 针对核糖核苷酸还原酶r1和r2组分的抗肿瘤反义序列 |
-
1997
- 1997-06-30 US US09/214,386 patent/US7223849B1/en not_active Expired - Fee Related
- 1997-06-30 JP JP10503679A patent/JP2000513230A/ja not_active Ceased
- 1997-06-30 WO PCT/CA1997/000454 patent/WO1998000532A2/en not_active Ceased
- 1997-06-30 EP EP97928071A patent/EP0954574A2/en not_active Withdrawn
- 1997-06-30 CA CA002259123A patent/CA2259123C/en not_active Expired - Fee Related
- 1997-06-30 AU AU32498/97A patent/AU3249897A/en not_active Abandoned
-
2005
- 2005-08-08 US US11/198,351 patent/US20070032442A1/en not_active Abandoned