JP2000505114A5 - - Google Patents

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Publication number
JP2000505114A5
JP2000505114A5 JP1998525182A JP52518298A JP2000505114A5 JP 2000505114 A5 JP2000505114 A5 JP 2000505114A5 JP 1998525182 A JP1998525182 A JP 1998525182A JP 52518298 A JP52518298 A JP 52518298A JP 2000505114 A5 JP2000505114 A5 JP 2000505114A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1998525182A
Other languages
English (en)
Japanese (ja)
Other versions
JP2000505114A (ja
JP4219409B2 (ja
Filing date
Publication date
Priority claimed from IT96MI002545A external-priority patent/IT1286522B1/it
Application filed filed Critical
Publication of JP2000505114A publication Critical patent/JP2000505114A/ja
Publication of JP2000505114A5 publication Critical patent/JP2000505114A5/ja
Application granted granted Critical
Publication of JP4219409B2 publication Critical patent/JP4219409B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP52518298A 1996-12-04 1997-12-01 5―アミノ―2,4,6―トリヨード―1,3―ベンゼンジカルボン酸誘導体を製造する方法 Expired - Fee Related JP4219409B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT96MI002545A IT1286522B1 (it) 1996-12-04 1996-12-04 Processo per la preparazione di derivati dell'acido 5-ammino-2,4,6- triiodo-1,3-benzenedicarbossilico
IT96A002545 1996-12-04
PCT/EP1997/006720 WO1998024757A1 (en) 1996-12-04 1997-12-01 A process for the preparation of 5-amino-2,4,6-triiodo-1,3-benzenedicarboxylic acid derivatives

Publications (3)

Publication Number Publication Date
JP2000505114A JP2000505114A (ja) 2000-04-25
JP2000505114A5 true JP2000505114A5 (enExample) 2005-09-08
JP4219409B2 JP4219409B2 (ja) 2009-02-04

Family

ID=11375347

Family Applications (1)

Application Number Title Priority Date Filing Date
JP52518298A Expired - Fee Related JP4219409B2 (ja) 1996-12-04 1997-12-01 5―アミノ―2,4,6―トリヨード―1,3―ベンゼンジカルボン酸誘導体を製造する方法

Country Status (12)

Country Link
EP (1) EP0901460B1 (enExample)
JP (1) JP4219409B2 (enExample)
AU (1) AU5657798A (enExample)
CA (1) CA2244884A1 (enExample)
DE (2) DE901460T1 (enExample)
ES (1) ES2129384T3 (enExample)
IN (1) IN185038B (enExample)
IT (1) IT1286522B1 (enExample)
NO (1) NO322067B1 (enExample)
PT (1) PT901460E (enExample)
WO (1) WO1998024757A1 (enExample)
ZA (1) ZA9710862B (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6803485B2 (en) * 1999-02-26 2004-10-12 Bracco Imaging S.P.A. Process for the preparation of iopamidol
CN100344606C (zh) * 2005-12-28 2007-10-24 江苏省原子医学研究所 一种碘昔兰的制备方法
KR101098553B1 (ko) 2008-04-30 2011-12-26 주식회사 엘지생명과학 이오프로마이드의 신규한 제조방법
MX2011005236A (es) * 2008-11-18 2011-06-16 Bracco Imaging Spa Proceso para la preparacion de agente de contraste yodado.
EP2230227A1 (en) 2009-03-20 2010-09-22 Bracco Imaging S.p.A Process for the preparation of triiodinated carboxylic aromatic derivatives
EP2243767A1 (en) 2009-04-21 2010-10-27 Bracco Imaging S.p.A Process for the iodination of aromatic compounds
AU2013357598B2 (en) 2012-12-11 2017-12-21 Bracco Imaging Spa Continuous process for the preparation of (S)-2-acetyloxypropionic acid chloride
KR101520187B1 (ko) 2013-10-25 2015-05-13 주식회사 대웅제약 이오프로마이드의 중간체의 제조방법
HUE039440T2 (hu) 2013-11-05 2018-12-28 Bracco Imaging Spa Eljárás lopamidol elõállítására
JP6546609B2 (ja) 2014-06-10 2019-07-17 ブラッコ・イメージング・ソシエタ・ペル・アチオニBracco Imaging S.P.A. (s)−2−アセチルオキシプロピオン酸およびその誘導体の製造方法
PT108524B (pt) * 2015-06-02 2017-12-15 Hovione Farmaciência S A Processo para a preparação de intermediários úteis na preparação de agentes de contraste não-iónicos
US10836710B2 (en) 2016-12-05 2020-11-17 Bracco Imaging Spa Mechanochemical synthesis of radiographic agents intermediates
CN116354842B (zh) * 2021-12-20 2024-12-03 重庆圣华曦药业股份有限公司 一种改进的碘美普尔制备方法及其在制剂中的应用
CN117776961A (zh) * 2023-12-28 2024-03-29 浙江海昌药业股份有限公司 一种碘比醇杂质及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH608189A5 (enExample) * 1974-12-13 1978-12-29 Savac Ag
US5075502A (en) * 1989-12-13 1991-12-24 Mallinckrodt, Inc. Nonionic x-ray contrast agents, compositions and methods
WO1993016981A1 (en) * 1992-02-28 1993-09-02 Mallinckrodt Medical, Inc. Synthesis of ioversol using a minimal excess of acetoxyacetylchloride

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