JP2000503321A5 - - Google Patents
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- Publication number
- JP2000503321A5 JP2000503321A5 JP1997526110A JP52611097A JP2000503321A5 JP 2000503321 A5 JP2000503321 A5 JP 2000503321A5 JP 1997526110 A JP1997526110 A JP 1997526110A JP 52611097 A JP52611097 A JP 52611097A JP 2000503321 A5 JP2000503321 A5 JP 2000503321A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/588,711 | 1996-01-19 | ||
| US08/588,711 US5804686A (en) | 1996-01-19 | 1996-01-19 | fused pyrrolecarboxamides; a new class of GABA brain receptor ligands |
| PCT/US1997/000519 WO1997026243A1 (en) | 1996-01-19 | 1997-01-14 | Novel fused pyrrolecarboxamides; a new class of gaba brain receptor ligands |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2000503321A JP2000503321A (ja) | 2000-03-21 |
| JP2000503321A5 true JP2000503321A5 (https=) | 2004-11-18 |
Family
ID=24354983
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP9526110A Ceased JP2000503321A (ja) | 1996-01-19 | 1997-01-14 | 新規な融合ピロールカルボキサミド；新規な種類のｇａｂａ脳リセプタリガンド |
Country Status (26)
| Country | Link |
|---|---|
| US (2) | US5804686A (https=) |
| EP (1) | EP1019372B1 (https=) |
| JP (1) | JP2000503321A (https=) |
| KR (1) | KR100490108B1 (https=) |
| CN (1) | CN1209805A (https=) |
| AP (1) | AP1015A (https=) |
| AT (1) | ATE322480T1 (https=) |
| AU (1) | AU1746697A (https=) |
| BG (1) | BG102634A (https=) |
| BR (1) | BR9707051A (https=) |
| CA (1) | CA2243317C (https=) |
| CZ (1) | CZ215498A3 (https=) |
| DE (1) | DE69735647T2 (https=) |
| ES (1) | ES2263170T3 (https=) |
| HU (1) | HUP9901018A3 (https=) |
| IL (1) | IL125391A (https=) |
| IS (1) | IS4798A (https=) |
| MX (1) | MX9805701A (https=) |
| NO (1) | NO312670B1 (https=) |
| NZ (1) | NZ330861A (https=) |
| OA (1) | OA10811A (https=) |
| PL (1) | PL327936A1 (https=) |
| RU (1) | RU2167151C2 (https=) |
| SK (1) | SK94398A3 (https=) |
| UA (1) | UA49001C2 (https=) |
| WO (1) | WO1997026243A1 (https=) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5750702A (en) * | 1993-10-27 | 1998-05-12 | Neurogen Corporation | Certain pyrrolo pyridine-3-carboxamides; a new class of GABA brain receptor ligands |
| US5804686A (en) * | 1996-01-19 | 1998-09-08 | Neurogen Corporation | fused pyrrolecarboxamides; a new class of GABA brain receptor ligands |
| US6211365B1 (en) | 1996-01-19 | 2001-04-03 | Neurogen Corporation | Fused pyrrolecarboxamides; a new class of GABA brain receptor ligands |
| WO1997034870A1 (en) | 1996-03-22 | 1997-09-25 | Neurogen Corporation | Certain fused pyrrolecarboxamides as gaba brain receptor ligands |
| US5723462A (en) * | 1996-04-26 | 1998-03-03 | Neurogen Corporation | Certain fused pyrrolecarboxamides a new class of GABA brain receptor ligands |
| IL135710A0 (en) | 1997-11-13 | 2001-05-20 | Pfizer Prod Inc | Method of synthesis of pyrrole amides |
| GT199800179A (es) * | 1997-11-13 | 2000-05-02 | Procedimiento de sintesis de pirrol amidas. | |
| AU2881199A (en) * | 1998-02-26 | 1999-09-15 | Neurogen Corporation | Substituted 1,4-dihydro-4-oxonicotinic carboxamides: gaba brain receptor ligands |
| GB9812038D0 (en) | 1998-06-04 | 1998-07-29 | Merck Sharp & Dohme | Therapeutic compound |
| AU5444499A (en) * | 1998-09-01 | 2000-03-21 | Nissan Chemical Industries Ltd. | Benzoxazine derivatives |
| US20050014939A1 (en) * | 1999-08-31 | 2005-01-20 | Neurogen Corporation | Fused pyrrolecarboxamides: GABA brain receptor ligands |
| OA12015A (en) * | 1999-08-31 | 2006-04-19 | Neurogen Corp | Fused pyrrolecarboxamides: gaba brain receptor ligands. |
| AU2001264932A1 (en) * | 2000-05-26 | 2001-12-11 | Neurogen Corporation | Oxo-imidazopyrimidine-carboxamides and their use as gaba brain receptor ligands |
| CA2419958A1 (en) * | 2000-09-06 | 2002-03-14 | Neurogen Corporation | Substituted fused pyrroleimines and pyrazoleimines |
| BR0113697A (pt) * | 2000-09-06 | 2003-07-22 | Neurogen Corp | Composto ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, uso de um composto ou sal, embalagem e métodos para, para alterar a atividade transdutora de sinal dos receptores de gabaa, para tratar ansiedade, depressão, um distúrbio do sono, ou demência de alzheimer, para demonstrar a presença dos receptores de gabaa em células ou amostras de tecido e para preparar um composto |
| EP1339681A1 (en) * | 2000-12-04 | 2003-09-03 | Pfizer Products Inc. | Synthesis of fused pyrrolecarboxamides |
| BR0307504A (pt) * | 2002-02-07 | 2004-12-07 | Neurogen Corp | Composto ou sal farmaceuticamente aceitável, composição farmacêutica, métodos tratar doenças, para potencializar um efeito terapêutico de um agente para o snc, para melhorar a memória de curto prazo em um paciente, para determinar a presença ou ausência de receptores gabaa em uma amostra, e para alterar a atividade transdutora de sinal do receptor gabaa, embalagem, e, uso de um composto ou sal |
| DE60306918T2 (de) * | 2002-05-17 | 2007-03-01 | Neurogen Corp., Branford | Substituierte, ringkondensierte imidazolderivate: gabaa-rezeptorliganden |
| EP1928437A2 (en) | 2005-08-26 | 2008-06-11 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation |
| EP2258358A3 (en) | 2005-08-26 | 2011-09-07 | Braincells, Inc. | Neurogenesis with acetylcholinesterase inhibitor |
| EP1940389A2 (en) | 2005-10-21 | 2008-07-09 | Braincells, Inc. | Modulation of neurogenesis by pde inhibition |
| US20070112017A1 (en) * | 2005-10-31 | 2007-05-17 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
| US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| WO2007134077A2 (en) | 2006-05-09 | 2007-11-22 | Braincells, Inc. | 5 ht receptor mediated neurogenesis |
| AU2007249399A1 (en) | 2006-05-09 | 2007-11-22 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
| EP2068872A1 (en) | 2006-09-08 | 2009-06-17 | Braincells, Inc. | Combinations containing a 4-acylaminopyridine derivative |
| US10954231B2 (en) | 2006-10-16 | 2021-03-23 | Bionomics Limited | Anxiolytic compounds |
| JP5373613B2 (ja) | 2006-10-16 | 2013-12-18 | バイオノミクス リミテッド | 新規な抗不安薬化合物 |
| WO2010099217A1 (en) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
| AU2011297160B2 (en) | 2010-08-31 | 2014-11-20 | Mitsui Chemicals Crop & Life Solutions, Inc. | Noxious organism control agent |
| CA2828780A1 (en) | 2011-03-02 | 2012-09-07 | Bionomics Limited | Novel small-molecules as therapeutics |
| EP2707367B1 (en) | 2011-05-12 | 2019-10-09 | Bionomics Limited | Methods for preparing naphthyridines |
| CN120081825B (zh) * | 2025-05-07 | 2025-09-16 | 天津匠新致成科技有限公司 | 一种化合物及其制备方法和医药用途 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3455943A (en) * | 1966-10-21 | 1969-07-15 | American Cyanamid Co | Certain 5,8-dihydro-beta-carbolines |
| US4075343A (en) * | 1976-09-13 | 1978-02-21 | Pfizer Inc. | Anti-allergenic 5-alkoxyimidazo[1,2-A]quinoline-2-carboxylic acids and derivatives thereof |
| DE3029980A1 (de) * | 1980-08-08 | 1982-03-11 | Boehringer Mannheim Gmbh, 6800 Mannheim | Indolderivate und verfahren zu ihrer herstellung |
| JPS57123180A (en) * | 1980-12-17 | 1982-07-31 | Schering Ag | 3-substituted beta-carboline, manufacture and psychotropic drug containing same |
| DE3147276A1 (de) * | 1981-11-28 | 1983-06-09 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren zur herstellung von indolderivaten, deren verwendung als wertvolle zwischenprodukte und neue 4-hydroxyindole |
| DE3246932A1 (de) * | 1982-12-16 | 1984-06-20 | Schering AG, 1000 Berlin und 4709 Bergkamen | Substituierte 5h-pyrimido(5,4-b)indole |
| DE3335323A1 (de) * | 1983-09-27 | 1985-04-04 | Schering AG, 1000 Berlin und 4709 Bergkamen | Substituierte ss-carboline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| GB8429739D0 (en) * | 1984-11-24 | 1985-01-03 | Fbc Ltd | Fungicides |
| DE3535927A1 (de) * | 1985-10-04 | 1987-04-09 | Schering Ag | 3-vinyl- und 3-ethinyl-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel |
| JPH06502147A (ja) * | 1990-10-09 | 1994-03-10 | ニューロゲン コーポレイション | 或る種のシクロアルキルおよびアザシクロアルキルピロロピリミジン；新規な種類のｇａｂａ脳リセプタリガンド |
| US5243049A (en) * | 1992-01-22 | 1993-09-07 | Neurogen Corporation | Certain pyrroloquinolinones: a new class of GABA brain receptor ligands |
| EP0626966A1 (en) * | 1992-02-19 | 1994-12-07 | PHARMACIA & UPJOHN COMPANY | 3-substituted imidazo(1,5-a)quinoxalines and quinazolines with cns activity |
| US5266698A (en) * | 1992-04-30 | 1993-11-30 | Neurogen Corporation | Certain aryl and cycloalkyl fused imidazopyrazinediones; a new class of GABA brain receptor ligands |
| WO1994017095A1 (en) * | 1993-01-29 | 1994-08-04 | Ariad Pharmaceuticals, Inc. | Analogs of receptor tyrosine activation motifs and therapeutic uses thereof |
| FR2705095B1 (fr) * | 1993-05-12 | 1995-06-23 | Adir | Nouveaux indoles substitués, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
| US5484944A (en) * | 1993-10-27 | 1996-01-16 | Neurogen Corporation | Certain fused pyrrolecarboxanilides and their use as GABA brain receptor ligands |
| US5804686A (en) * | 1996-01-19 | 1998-09-08 | Neurogen Corporation | fused pyrrolecarboxamides; a new class of GABA brain receptor ligands |
-
1996
- 1996-01-19 US US08/588,711 patent/US5804686A/en not_active Expired - Fee Related
-
1997
- 1997-01-14 ES ES97904754T patent/ES2263170T3/es not_active Expired - Lifetime
- 1997-01-14 RU RU98115534/04A patent/RU2167151C2/ru not_active IP Right Cessation
- 1997-01-14 UA UA98073904A patent/UA49001C2/uk unknown
- 1997-01-14 PL PL97327936A patent/PL327936A1/xx unknown
- 1997-01-14 IL IL12539197A patent/IL125391A/en not_active IP Right Cessation
- 1997-01-14 HU HU9901018A patent/HUP9901018A3/hu unknown
- 1997-01-14 KR KR10-1998-0705446A patent/KR100490108B1/ko not_active Expired - Fee Related
- 1997-01-14 CZ CZ982154A patent/CZ215498A3/cs unknown
- 1997-01-14 DE DE69735647T patent/DE69735647T2/de not_active Expired - Fee Related
- 1997-01-14 WO PCT/US1997/000519 patent/WO1997026243A1/en not_active Ceased
- 1997-01-14 SK SK943-98A patent/SK94398A3/sk unknown
- 1997-01-14 NZ NZ330861A patent/NZ330861A/xx unknown
- 1997-01-14 AU AU17466/97A patent/AU1746697A/en not_active Abandoned
- 1997-01-14 BR BR9707051A patent/BR9707051A/pt not_active Application Discontinuation
- 1997-01-14 AT AT97904754T patent/ATE322480T1/de not_active IP Right Cessation
- 1997-01-14 CN CN97191759A patent/CN1209805A/zh active Pending
- 1997-01-14 CA CA002243317A patent/CA2243317C/en not_active Expired - Fee Related
- 1997-01-14 AP APAP/P/1998/001297A patent/AP1015A/en active
- 1997-01-14 JP JP9526110A patent/JP2000503321A/ja not_active Ceased
- 1997-01-14 EP EP97904754A patent/EP1019372B1/en not_active Expired - Lifetime
-
1998
- 1998-07-15 OA OA9800115A patent/OA10811A/en unknown
- 1998-07-15 BG BG102634A patent/BG102634A/xx unknown
- 1998-07-15 MX MX9805701A patent/MX9805701A/es not_active IP Right Cessation
- 1998-07-16 IS IS4798A patent/IS4798A/is unknown
- 1998-07-17 NO NO19983315A patent/NO312670B1/no not_active IP Right Cessation
- 1998-09-04 US US09/148,247 patent/US6080873A/en not_active Expired - Fee Related