JP2000034218A - Preparing for external use for skin - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a preparation for external use for skin having excellent compatibility with skin free from greasiness, capable of forming a proper coating film on the skin, having excellent sense of tenseness. SOLUTION: This preparation for external use for skin comprises 0.001-5.0 wt.% of a coating agent such as a polyvinyl pyrrolidone-based coating agent, an acrylic acid-based coating agent, a vinyl acetate-based coating agent, a methacrylic acid-based coating agent, a vinyl methyl ether-based coating agent, a styrene-based coating agent, an alkyd resin-based coating agent, a silicone- based coating agent, a cationized cellulose and a polyvinyl alcohol and 0.001-10.0 wt.% of fermented soybeans essence.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an external preparation for the skin, and more particularly, to an external preparation for the skin which has good skin familiarity, has no stickiness, and forms an appropriate film on the skin to give a good feeling of sticking. Things.

[0002]

2. Description of the Related Art Conventionally, an external preparation for skin which gives a feeling of sticking to the skin has been formulated with a water-soluble or oil-soluble polymer, and the polymer is coated on the skin surface. It gave a feeling of beam. However, a skin external preparation that incorporates a water-soluble or oil-soluble polymer and gives a sufficient feeling of stickiness is strongly sticky due to the viscosity at the time of evaporation of the solvent generated when the polymer is coated on the skin. There was a drawback that the properties were not good. For this reason, there has been a demand for the development of an external preparation for skin which can sufficiently feel a feeling of stickiness and which is less sticky to polymers and has good usability.

The present invention has been made in view of the above-mentioned problems of the prior art, and an object of the present invention is to provide an external preparation for the skin which does not give stickiness after application on the skin, has good adaptability to the skin, and gives an appropriate stickiness. Is to do.

[0004]

Means for Solving the Problems In view of the above-mentioned circumstances, the present inventors have conducted intensive studies. As a result, the combination of a coating agent and a natto extract provides good adaptability to the skin and is sticky after application. The present inventors have found that an external preparation for skin with an excellent feeling of use, which has a small amount of odor and a sufficient feeling of sticking to the skin, can be obtained, and has completed the present invention.

That is, according to the present invention, (A) the coating agent is used in 0.1.
001-5.0% by weight and (B) natto extract in 0.00
1 to 10.0% by weight.

Hereinafter, the present invention will be described in detail. As the coating agent (A) used in the present invention, polyvinylpyrrolidone (PVP), PVP / dimethylaminoethyl methacrylic acid copolymer, PVP / eicosene copolymer, P
Polyvinylpyrrolidone such as VP / ethyl methacrylate / ethyl methacrylate copolymer, PVP / hexadecene copolymer, PVP / vinyl acetate copolymer, PVP / vinyl acetate / itaconic acid copolymer, PVP / styrene copolymer Coating agent, ethyl acrylate / acrylamide / acrylic acid copolymer, ethyl acrylate / butyl acrylate copolymer, ethyl acrylate / ethyl methacrylate copolymer, ethyl acrylate / methacrylic acid copolymer, Ethyl acrylate / methyl methacrylate copolymer, octyl acrylate / vinyl acetate copolymer, octyl acrylate / styrene copolymer, alkyl styrene acrylate copolymer, butyl acrylate / vinyl acetate copolymer, acrylic acid Butyl / ethyl hydroxymethacrylate copolymer, Le butyl / methyl methacrylate copolymer, methoxyethyl / hydroxyethyl acrylate / butyl acrylate copolymer acrylate, lauryl acrylate / vinyl acetate copolymer, ethyl polyacrylate,
Acrylic coating agents such as polybutyl acrylate and polystyrene acrylate resin, vinyl acetate coating agents such as polyvinyl acetate, polymethyl methacrylate, methyl methacrylate / butyl acrylate / octyl acrylate, and vinylpyrrolidone diethyl sulfate / Methacrylic acid-based coating agents such as N, N'-dimethylaminomethacrylic acid copolymer; vinyl methyl ether-based coating agents such as vinyl methyl ether / maleic butyl copolymer; styrene such as styrene / methyl styrene / indene copolymer Coating agents, alkyd resin coating agents such as cyclohexane alkyd resin, silicone resin coating agents such as trimethylsiloxysilicic acid, synthetic resin emulsions capable of forming a film such as organopolysiloxane, and water- or alcohol-soluble polyvinyl alcohol Kind, water-insoluble Cellulosic polymers such as nitrocellulose, cationized cellulose, methylcellulose, ethylcellulose, methylhydroxypropylcellulose, hydroxyethylcellulose, cellulose sodium sulfate, hydroxypropylcellulose, sodium carboxymethylcellulose (CMC), crystalline cellulose, and cellulose powder. Can be

[0007] Of these coating agents, particularly preferred are:
Polyvinylpyrrolidone coating agent, acrylic acid coating agent,
Vinyl acetate coating agent, methacrylic acid coating agent, vinyl methyl ether coating agent, styrene coating agent, alkyd resin coating agent, silicone resin coating agent, cationized cellulose and polyvinyl alcohol, among which polyvinyl Alcohols are preferred.

The compounding amount of the coating agent is 0.001 to 5.0% by weight, preferably 0.01 to 3.0% by weight, in the external preparation for skin of the present invention. If the amount is less than 0.001% by weight based on the total amount of the external preparation for skin, a sufficient feeling of stickiness cannot be obtained, and even if the amount exceeds 5.0% by weight, no increase in stickiness is observed, Undesirably, high-molecular swelling occurs on the skin and scum occurs on the skin, resulting in impaired use feeling of the external preparation.

[0009] The (B) natto extract used in the present invention comprises:
Bacillus natto
A solution obtained by adding anhydrous ethanol to a 20% ethanol extract of Bacillus natto produced by fermentation with Sawamura, and dispersing a lumpy mucus which precipitates in a 10% ethanol solution (lump mucus: 10% ethanol solution = about 2) : 98)
This is a viscous extract containing a γ-glutamic acid polymer as a main component and also containing sugar and the like. As a commercial product,
"Phytocollage" (trade name, manufactured by Ichimaru Falcos Co., Ltd.).

The amount of the natto extract in the external preparation for skin of the present invention is 0.001 to 10.0% by weight, preferably 0.01 to 5.0% by weight, based on the whole external preparation. The amount of natto extract is 0.00
If the amount is less than 1% by weight, it becomes practically difficult to improve the familiarity of the external preparation and exert the repelling effect, which is not preferable. Is not observed, and the polymer is distorted on the skin, and scum is generated on the skin, which undesirably impairs the feeling of use of the external preparation.

The external preparation for skin of the present invention may contain, in addition to the above-mentioned basic ingredients, if necessary, other components usually used in external preparations for skin such as cosmetics and pharmaceuticals to achieve the desired effects of the present invention. It can be appropriately compounded as long as it is not impaired. These may be used not only alone but also in combination of two or more of these other components.

Such components include, for example, hydrocarbons such as liquid paraffin, squalane and petrolatum; fats and oils such as macadamia nut oil, olive oil and lanolin; waxes such as jojoba oil, carnauba wax and candelilla wax, dimethylpolysiloxane, methyl Silicones such as phenylpolysiloxane and cyclic silicones; higher alcohols such as caprylic alcohol, lauryl alcohol, myristyl alcohol, cetyl alcohol, cholesterol, phytosterol; capric acid, myristic acid, palmitic acid, stearic acid, behenic acid, lanolin Fatty acids, higher fatty acids such as linoleic acid and linolenic acid; polyethylene glycol, glycerin, 1,3-butylene glycol, erythritol, sorbitol, xylitol, maltitol, etc. Wetting agents; quince seed, carrageenan, pectin, mannan, curdlan, starch, galactan, glycogen, gum arabic, xanthan gum, hydroxyethyl guar gum, carboxymethyl guar gum, guar gum, dextran, locust bean gum, succinoglucan, caronic acid, chitin Thickeners such as thiol, chitosan, carboxymethyl chitin, agar; lower alcohols such as ethanol; antioxidants such as butylhydroxytoluene, tocopherol, phytin; benzoic acid, salicylic acid, sorbic acid, alkyl esters of parahydroxybenzoic acid, hexachlorophene, etc. Antibacterial agents such as paraaminobenzoic acid-based ultraviolet absorbers, anthranilic acid-based ultraviolet absorbers, salicylic acid-based ultraviolet absorbers, cinnamic acid-based ultraviolet absorbers, benzophenone-based ultraviolet absorbers, and sugar-based agents External absorbent, 3- (4'-methylbenzylidene)-d-camphor, 3-benzylidene -d, l-camphor, urocanic acid, urocanic acid ethyl ester, 2-phenyl -
5-methylbenzoxazole, 2,2'-hydroxy-
5-methylphenylbenzotriazole, 2- (2′-
(Hydroxy-5′-t-octylphenyl) benzotriazole, 2- (2′-hydroxy-5′-methylphenyl) benzotriazole, dibenzarazine, dianisoylmethane, 4-methoxy-4′-t-butyldibenzoylmethane, UV absorbers such as 5- (3,3-dimethyl-2-norbornylidene) -3-pentan-2-one;
Organic acids such as acyl sarcosine acid (eg, sodium lauroyl sarcosine), glutathione, citric acid, malic acid, tartaric acid, and lactic acid; vitamin A and its derivatives, vitamin B6 hydrochloride, vitamin B6 tripalmitate, vitamin B6 dioctanoate, vitamin B2 and Vitamin B such as derivatives thereof, vitamin B12, vitamin B15 and derivatives thereof, vitamin Cs such as ascorbic acid, ascorbic acid sulfate (salt), ascorbic acid phosphate (salt), ascorbic acid dipalmitate, α-tocopherol, Vitamin E such as β-tocopherol, γ-tocopherol, vitamin E acetate, vitamin D, vitamin H, pantothenic acid, pantethine and other vitamins; nicotinamide, benzyl nicotinate, γ-
Saponins such as oryzanol, allantoin, glycyrrhizic acid (salt), glycyrrhetinic acid and its derivatives, hinokitiol, bisabolol, eucalptone, thymol, inositol, saikosaponin, carrot saponin, hemimasaponin, muclodisaponin and the like; pantothenyl ethyl ether, ethynyl Various drugs such as estradiol, tranexamic acid, arbutin, cepharanthin, placenta extract;
Orange, sage, yarrow, mallow, thyme, thyme, spruce, spruce, birch, horsetail, luffa, marronnier, yukinoshita, arnica, lily, mugwort,
Extracts of plants such as peonies, aloe, gardenia and sawara; pigments: sorbitan monolaurate, sorbitan monopalmitate, sorbitan sesquioleate, sorbitan trioleate, polyoxyethylene sorbitan monolaurate, polyoxetylene sorbitan monostearate, Nonionic activators such as polyethylene glycol monooleate, polyoxyethylene alkyl ether, polyglycol diether, lauroyl diethanol amide, fatty acid isopropanol amide, maltitol hydroxy fatty acid ether, alkylated polysaccharide, alkyl glucoside, and sugar ester; stearyl trimethyl ammonium Cationic surfactants such as chloride, benzalkonium chloride, laurylamine oxide; sodium palmitate Surfactants such as sodium laurate, sodium laurate, potassium lauryl sulfate, alkyl triethanolamine ether, funnel oil, linear dodecyl benzene sulfate, polyoxyethylene hydrogenated castor oil, maleic acid, and acylmethyl taurine; amphoteric interface Activators, neutralizers, antioxidants, fragrances, purified water and the like can be added.

The dosage form that the external preparation for skin of the present invention can take is not particularly limited, and examples thereof include an aqueous solution, a solubilizing system, an emulsifying system, a powder dispersing system, a water-oil two-layer system, and a water-oil-powder three-layer system. The present invention can be applied to all aspects of the present invention. In addition, it is used for many applications such as basic cosmetics such as lotion, milky lotion, cream, and pack, makeup cosmetics such as lipstick, foundation, etc., hair products such as shampoo, rinse and hair dye, and special cosmetics such as sunscreen. Of different types.

[0014]

The present invention will be described below in more detail with reference to examples, but the technical scope of the present invention should not be construed as being limited to these examples. In addition, about the compounding amount, unless otherwise specified, it shows weight%.

Examples 1 to 5 and Comparative Examples 1 to 6 Lotions were prepared according to the conventional methods in accordance with the formulations shown in Tables 1 and 2. For each lotion obtained, 3
A total of 60 panels were asked to judge the feeling of use, and the familiarity of the skin, the feeling of stickiness of the skin, and the feeling of sticking of the skin were judged based on the number of panels. The evaluation criteria are as follows. The results are shown in Tables 1 and 2.

(1) Evaluation criteria for skin familiarity A: 30 or more people felt that skin familiarity was good. ：: 10 or more and less than 30 people felt that skin familiarity was good. Δ: 5 or more and less than 10 people felt skin familiarity was good. ×: Less than 5 people felt that skin familiarity was good.

(2) Evaluation criteria for stickiness of skin A: 30 or more people felt non-sticky. ：: 10 or more and less than 30 people felt non-sticky. Δ: 5 or more and less than 10 people felt non-sticky. ×: Less than 5 people felt non-sticky.

(3) Evaluation criteria for skin swelling A: 30 or more people felt skin swelling. ：: 10 or more and less than 30 people felt skin swelling. Δ: 5 or more and less than 10 people felt skin swelling. ×: Less than 5 people felt skin swelling.

[0019]

[Table 1] {Example 1 2 3 4 5} ───────────────────────────── 1,3-butylene glycol 4.0 4.0 4.0 4.0 4.0 POE (20) oleyl alcohol ether 0.5 0.5 0.5 0.5 0.5 Polyvinyl alcohol 0.1 5.0 0.01 3.0 0.001 Natto extract ^{* 1)} 0.1 0.01 5.0 7.0 7.0 Preservatives Appropriate amount Appropriate amount Appropriate amount Appropriate amount Perfume Appropriate amount Appropriate amount Appropriate amount Appropriate amount Purified water Residue Residue Residue Residue ───────────み Skin familiarity ○ ○ ◎ ◎ ◎ Skin stickiness ◎ ◎ ◎ ◎ ◎ Skin stickiness ○ ○ ○ ◎ ○ ── ────────────────────────────────

[0020]

[Table 2] {Comparative Example 1 2 3 4 5 6} ────────────────────────────── 1,3-butylene glycol 4.0 4.0 4.0 4.0 4.0 4.0 POE (20) Oleyl alcohol ether 0.5 0.5 0.5 0.5 0.5 0.5 Polyvinyl alcohol-5.0 0.001 0.0001-5.0 Natto extract ^{* 1)} ---5.0 0.1 0.0001 Preservatives qs qq qq qq qq qq qq.perfume qq qq qq qq qq qq qq Purified water residue residue residue residue residue ─────────────────────────────── Skin familiarity △ △ △ ○ ○ △ Skin stickiness ○ × △ ○ △ △ Skin Stickiness × △ △ △ △ ○ ──────────────────────────────────

* 1) "Phytocollage", manufactured by Ichimaru Falcos Co., Ltd. As shown in Tables 1 and 2, the inclusion of polyvinyl alcohol as a coating agent and natto extract provided an excellent synergistic effect of these components. It turns out that it shows a feeling of use. Next, a formulation example of the skin external preparation of the present invention will be shown.

Example 6 Cream (1) Cetyl alcohol 5.0% by weight (2) Stearic acid 3.0 (3) Vaseline 5.0 (4) Squalane 10.0 (5) Glycerol tri-2-ethylhexanoate 7.0 (6) Dipropylene glycol 5.0 (7) Glycerin 5.0 (8) Propylene glycol monostearate 1.5 (9) POE (20) cetyl alcohol ether 1.5 (10) Triethanolamine 1.0 (11) Polyvinyl alcohol 1.0 (12) Natto extract 3.0 ("Phytocollage", manufactured by Ichimaru Falcos Co., Ltd.) (13) Rice germ oil qs (14) Royal jelly extract qs (15) Preservative Agent proper amount (16) antioxidant proper amount (17) fragrance proper amount (18) purified water residue (production method) After adding humectant, natto extract and royal jelly extract to purified water, add polyvinyl alcohol to some purified water separately Was dissolved at 80 ° C., and adjusted to 70 ° C. (aqueous phase). Next, after dissolving the oil by heating, a surfactant, a preservative, an antioxidant and a fragrance are added thereto,
The temperature was adjusted to 0 ° C. This was added to the previous aqueous phase to perform preliminary emulsification. After homogenizing the emulsified particles of the pre-emulsion with a homomixer, deaeration, filtration and cooling were performed to obtain a desired cream.

Example 7 Emulsion (1) Cetyl alcohol 1.0% by weight (2) Beeswax 0.5 (3) Vaseline 2.0 (4) Squalane 6.0 (5) Dimethylpolysiloxane 2.0 (6) Ethanol 5.0 (7) Glycerin 4.0 (8) 1,3-butylene glycol 4.0 (9) POE (10) monooleate 1.0 (10) Glycerol monostearate 1.0 (11 ) Trimethylsiloxysilicic acid 2.0 (12) Natto extract 3.0 ("Phytocollage", manufactured by Ichimaru Falcos Co., Ltd.) (13) Hamameris proper amount (14) Preservative proper amount (15) Colorant proper amount (16) Perfume proper amount (17) Purified water residue (Preparation method) A humectant, natto extract, hamamelis, and a coloring agent were added to purified water, and the mixture was heated to 70 ° C. (aqueous phase). Next, trimethylsiloxysilicic acid, a surfactant and a preservative were added to the oil, and the mixture was heated to 70 ° C. and adjusted. This is added to the previous aqueous phase to perform pre-emulsification, and a preservative and ethanol are added to the pre-emulsion, followed by stirring, homogenizing the emulsified particles with a homomixer, followed by degassing, filtration and cooling. The desired emulsion was obtained.

Example 8 Foundation (1) Talc 3.0% by weight (2) Titanium dioxide 5.0 (3) Bengala 0.5 (4) Yellow iron oxide 1.4 (5) Black iron oxide 0.1 ( 6) Polyoxyethylene sorbitan monostearate 0.9 (7) Triethanolamine 1.0 (8) Propylene glycol 5.0 (9) Polyvinyl alcohol 0.5 (10) Natto extract 5.0 ("Phytocollage") (11) Vitamin E acetate 0.5 (12) Stearic acid 2.2 (13) Isohexadecyl alcohol 7.0 (14) Glycerin monostearate 2.0 (15) Liquid lanolin 2 8.0 (16) Liquid paraffin 8.0 (17) Preservatives proper amount (18) Fragrance proper amount (19) Purified water residue (Preparation method) Add polyvinyl alcohol to some purified water at 80 ° C
Was dissolved in purified water, and the remaining aqueous phase components were added thereto and sufficiently stirred. The powder components sufficiently mixed and pulverized were added thereto with stirring, and homomixer treatment was performed at 70 ° C. This was cooled with stirring, and when the temperature of the system reached 45 ° C., a fragrance was added. Finally, the mixture was degassed and filled in a container to obtain a desired foundation.

The skin external preparations of Examples 6 to 8 are suitable for skin
In the effect tests on the sticky feeling and the skin sticking feeling, the same results as in Examples 1 to 5 were obtained.

[0026]

As described above, the external preparation for skin of the present invention has good skin familiarity, has no stickiness, and forms an appropriate film on the skin to give a good feeling of sticking.

 ──────────────────────────────────────────────────続 き Continued on the front page (72) Inventor Koji Abe 1050 Nippa-cho, Kohoku-ku, Yokohama-shi, Kanagawa F-term in Shiseido Daiichi Research Center Co., Ltd. 4C083 AA082 AA111 AA112 AA122 AB232 AB242 AB432 AC012 AC022 AC072 AC092 AC102 AC122 AC182 AC242 AC392 AC402 AC422 AC442 AC542 AD042 AD112 AD152 AD162 AD512 AD662 CC02 CC05 CC12 DD23 DD31 DD38 EE06 EE12 FF05

Claims (1)

[Claims] (A) 0.001 to 5.0% by weight of a coating agent and (B) 0.001 to 10.0% by weight of a natto extract.
And an external preparation for skin, characterized by comprising: