JO3187B1 - (4-(8- ميثوكسي بروبان -2-يل)-2-(تترا هيدرو - 2h - بيران-4-يل)- 1h - ايميدازو [ 4, 5- c ] كوينولين -7-يل)-3, 5- داي ميثيل ايزوكسازول واستخدامه كمثبط نطاق برومو - Google Patents

(4-(8- ميثوكسي بروبان -2-يل)-2-(تترا هيدرو - 2h - بيران-4-يل)- 1h - ايميدازو [ 4, 5- c ] كوينولين -7-يل)-3, 5- داي ميثيل ايزوكسازول واستخدامه كمثبط نطاق برومو

Info

Publication number
JO3187B1
JO3187B1 JOP/2012/0229A JOP20120229A JO3187B1 JO 3187 B1 JO3187 B1 JO 3187B1 JO P20120229 A JOP20120229 A JO P20120229A JO 3187 B1 JO3187 B1 JO 3187B1
Authority
JO
Jordan
Prior art keywords
piran
imidazo
quinoline
bromo
propane
Prior art date
Application number
JOP/2012/0229A
Other languages
Arabic (ar)
English (en)
Inventor
Hubert Demont Emmanuel
J Watson Robert
Louise Jones Katherine
Original Assignee
Glaxosmithkline Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Llc filed Critical Glaxosmithkline Llc
Application granted granted Critical
Publication of JO3187B1 publication Critical patent/JO3187B1/ar

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JOP/2012/0229A 2011-08-17 2012-08-15 (4-(8- ميثوكسي بروبان -2-يل)-2-(تترا هيدرو - 2h - بيران-4-يل)- 1h - ايميدازو [ 4, 5- c ] كوينولين -7-يل)-3, 5- داي ميثيل ايزوكسازول واستخدامه كمثبط نطاق برومو JO3187B1 (ar)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1114103.3A GB201114103D0 (en) 2011-08-17 2011-08-17 Novel compounds

Publications (1)

Publication Number Publication Date
JO3187B1 true JO3187B1 (ar) 2018-03-08

Family

ID=44764570

Family Applications (1)

Application Number Title Priority Date Filing Date
JOP/2012/0229A JO3187B1 (ar) 2011-08-17 2012-08-15 (4-(8- ميثوكسي بروبان -2-يل)-2-(تترا هيدرو - 2h - بيران-4-يل)- 1h - ايميدازو [ 4, 5- c ] كوينولين -7-يل)-3, 5- داي ميثيل ايزوكسازول واستخدامه كمثبط نطاق برومو

Country Status (38)

Country Link
US (4) US9067936B2 (forum.php)
EP (2) EP3150601A1 (forum.php)
JP (1) JP6059723B2 (forum.php)
KR (1) KR20140064878A (forum.php)
CN (1) CN103889984B (forum.php)
AR (1) AR087545A1 (forum.php)
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IL (1) IL230489A (forum.php)
IN (1) IN2014CN00568A (forum.php)
JO (1) JO3187B1 (forum.php)
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UA (1) UA110838C2 (forum.php)
UY (1) UY34264A (forum.php)
WO (1) WO2013024104A1 (forum.php)

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Also Published As

Publication number Publication date
GB201114103D0 (en) 2011-09-28
SI2744809T1 (sl) 2017-01-31
IL230489A (en) 2016-07-31
HUE030106T2 (en) 2017-04-28
PT2744809T (pt) 2017-01-06
KR20140064878A (ko) 2014-05-28
BR112014003681A8 (pt) 2018-01-23
CO6862151A2 (es) 2014-02-10
PH12014500379A1 (en) 2021-07-12
TW201323424A (zh) 2013-06-16
US9861627B2 (en) 2018-01-09
US9416130B2 (en) 2016-08-16
US9610284B2 (en) 2017-04-04
EA201490200A1 (ru) 2014-07-30
DK2744809T3 (en) 2017-01-23
IL230489A0 (en) 2014-03-31
CN103889984B (zh) 2016-01-13
ES2609857T3 (es) 2017-04-24
HRP20161674T1 (hr) 2017-01-27
UY34264A (es) 2013-04-05
CA2843537A1 (en) 2013-02-21
JP2014521735A (ja) 2014-08-28
IN2014CN00568A (forum.php) 2015-04-03
AU2012296914A1 (en) 2014-02-13
BR112014003681A2 (pt) 2017-03-01
EA023374B1 (ru) 2016-05-31
SMT201700005T1 (it) 2017-03-08
PL2744809T3 (pl) 2017-08-31
EP3150601A1 (en) 2017-04-05
TWI558704B (zh) 2016-11-21
US20140171462A1 (en) 2014-06-19
ME02589B (me) 2017-06-20
AU2012296914B2 (en) 2016-03-03
US9067936B2 (en) 2015-06-30
MX350597B (es) 2017-09-11
NZ620263A (en) 2016-04-29
AR087545A1 (es) 2014-04-03
US20150315184A1 (en) 2015-11-05
DOP2014000031A (es) 2014-06-01
CY1118370T1 (el) 2017-06-28
PE20141406A1 (es) 2014-10-25
EP2744809A1 (en) 2014-06-25
MY170729A (en) 2019-08-27
US20170157113A1 (en) 2017-06-08
UA110838C2 (uk) 2016-02-25
LT2744809T (lt) 2016-12-27
WO2013024104A1 (en) 2013-02-21
RS55560B1 (sr) 2017-05-31
CL2014000365A1 (es) 2014-07-11
CN103889984A (zh) 2014-06-25
EP2744809B1 (en) 2016-10-12
US20160317529A1 (en) 2016-11-03
MX2014001834A (es) 2014-02-27
JP6059723B2 (ja) 2017-01-11
SMT201700005B (it) 2017-03-08
CR20140076A (es) 2014-03-19

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