JO1176B1 - Organic platinum compound, method of preparation and use in the treatment of malignant tumors - Google Patents

Organic platinum compound, method of preparation and use in the treatment of malignant tumors

Info

Publication number
JO1176B1
JO1176B1 JO19811176A JOP19811176A JO1176B1 JO 1176 B1 JO1176 B1 JO 1176B1 JO 19811176 A JO19811176 A JO 19811176A JO P19811176 A JOP19811176 A JO P19811176A JO 1176 B1 JO1176 B1 JO 1176B1
Authority
JO
Jordan
Prior art keywords
platinum
complex
malignant tumours
preparation
organic complex
Prior art date
Application number
JO19811176A
Other languages
Arabic (ar)
English (en)
Inventor
بيير ماكيت جان
Original Assignee
سانوفي اس.ايه
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by سانوفي اس.ايه filed Critical سانوفي اس.ايه
Application granted granted Critical
Publication of JO1176B1 publication Critical patent/JO1176B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235—Saturated compounds containing more than one carboxyl group
    • C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JO19811176A 1980-04-29 1981-06-15 Organic platinum compound, method of preparation and use in the treatment of malignant tumors JO1176B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8014109 1980-04-29

Publications (1)

Publication Number Publication Date
JO1176B1 true JO1176B1 (en) 1983-11-30

Family

ID=10513074

Family Applications (1)

Application Number Title Priority Date Filing Date
JO19811176A JO1176B1 (en) 1980-04-29 1981-06-15 Organic platinum compound, method of preparation and use in the treatment of malignant tumors

Country Status (32)

Country Link
US (1) US4452812A (enEXAMPLES)
EP (1) EP0039272B1 (enEXAMPLES)
JP (1) JPS595599B2 (enEXAMPLES)
AR (1) AR226354A1 (enEXAMPLES)
AT (1) AT372072B (enEXAMPLES)
AU (1) AU6978681A (enEXAMPLES)
BE (1) BE888367A (enEXAMPLES)
CA (1) CA1171425A (enEXAMPLES)
DD (1) DD158777A5 (enEXAMPLES)
DE (1) DE3163162D1 (enEXAMPLES)
DK (1) DK188481A (enEXAMPLES)
ES (1) ES8203324A1 (enEXAMPLES)
FI (1) FI811314L (enEXAMPLES)
FR (1) FR2481289B1 (enEXAMPLES)
GB (1) GB2077720B (enEXAMPLES)
GR (1) GR75598B (enEXAMPLES)
IE (1) IE51197B1 (enEXAMPLES)
IL (1) IL62615A0 (enEXAMPLES)
IT (1) IT1146749B (enEXAMPLES)
JO (1) JO1176B1 (enEXAMPLES)
LU (1) LU83325A1 (enEXAMPLES)
MA (1) MA19131A1 (enEXAMPLES)
MC (1) MC1391A1 (enEXAMPLES)
NO (1) NO811449L (enEXAMPLES)
NZ (1) NZ196803A (enEXAMPLES)
OA (1) OA06797A (enEXAMPLES)
PL (1) PL128539B1 (enEXAMPLES)
PT (1) PT72941B (enEXAMPLES)
RO (1) RO82032B (enEXAMPLES)
YU (1) YU102581A (enEXAMPLES)
ZA (1) ZA812474B (enEXAMPLES)
ZW (1) ZW8681A1 (enEXAMPLES)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59112995A (ja) * 1982-12-21 1984-06-29 Shionogi & Co Ltd 新規グリコ−ル酸白金錯体
WO1984004524A1 (en) * 1983-05-10 1984-11-22 Andrulis Res Corp Bis-platinum complexes as antitumor agents
US4565884A (en) * 1983-05-10 1986-01-21 Andrulis Research Corporation Bis-platinum complexes as antitumor agents
US4720504A (en) * 1983-05-10 1988-01-19 Andrulis Research Corporation Use of bis-platinum complexes as antitumor agents
DK301684A (da) * 1983-06-20 1984-12-21 Research Corp Diaminocyklohexanplatinkomplekser
US4758588A (en) * 1983-06-20 1988-07-19 Research Corporation Technologies Diaminocyclohexane platinum complexes
US4661516A (en) * 1983-06-20 1987-04-28 Research Corporation Diaminocyclohexane platinum complexes
US4562275A (en) * 1984-03-23 1985-12-31 Bristol-Myers Co. Antitumor platinum complexes
EP0169645A1 (en) * 1984-06-27 1986-01-29 Johnson Matthey Public Limited Company Platinum co-ordination compounds
DE3575144D1 (de) * 1984-12-17 1990-02-08 American Cyanamid Co Platinkomplexe von aliphatischen tricarbonsaeuren.
US5011959A (en) * 1986-11-17 1991-04-30 The Board Of Regents, The University Of Texas System 1,2-diaminocyclohexane-platinum complexes with antitumor activity
CA1283904C (en) * 1987-03-06 1991-05-07 Mitsuaki Maeda Liposoluble platinum (ii) complex and preparation thereof
US5393909A (en) * 1988-11-22 1995-02-28 Board Of Regents, The University Of Texas System Diamine platinum complexes as antitumor agents
DE69028844T2 (de) * 1989-12-12 1997-02-13 Toray Industries, Inc., Tokio/Tokyo Neuer platin(ii)komplex und mittel für die behandlung von bösartigen tumoren
JP3154399B2 (ja) * 1996-07-04 2001-04-09 デビオファーム エス．アー． 白金化合物の製造方法
US6689928B2 (en) 2000-04-04 2004-02-10 Exxonmobil Research And Engineering Company Transition metal complexes and oligomers therefrom
DE10206648A1 (de) * 2002-02-15 2003-09-11 November Ag Molekulare Medizin Wirkstoff zur Herstellung eines Stoffs zur Beeinflussung der Koagulationsbereitschaft des Bluts
WO2005056641A1 (ja) * 2003-12-10 2005-06-23 Toudai Tlo, Ltd. ジアミノシクロヘキサン白金(ii)とポリ(カルボン酸)セグメント含有ブロック共重合体との配位錯体、その抗腫瘍剤
DE102004005906B3 (de) * 2004-02-05 2005-09-29 W.C. Heraeus Gmbh Verfahren zur Herstellung von 1,2-Diaminocylohexan-Platin(II)-Komplexen
JP2006248978A (ja) 2005-03-10 2006-09-21 Mebiopharm Co Ltd 新規なリポソーム製剤
US20090082438A1 (en) * 2005-03-18 2009-03-26 Kazunori Kataoka Coordination Compound Composed of Diaminocyclohexane Platinum (II) and Block Copolymer and Anti-Cancer Agent Comprising the Same

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH588505A5 (enEXAMPLES) * 1972-06-08 1977-06-15 Research Corp
US4115418A (en) * 1976-09-02 1978-09-19 Government Of The United States Of America 1,2-diaminocyclohexane platinum (ii) complexes having antineoplastic activity
JPS6041077B2 (ja) * 1976-09-06 1985-09-13 喜徳 喜谷 １，２‐ジアミノシクロヘキサン異性体のシス白金（２）錯体
US4206226A (en) * 1977-08-29 1980-06-03 The United States Of America As Represented By The Department Of Health, Education And Welfare Use of 4-carboxy-phthalato-(1,2-diaminocyclohexane)-platinum(II) and alkali metal salts thereof in alleviating L1210 murine leukemia
JPS5829957B2 (ja) * 1977-09-12 1983-06-25 喜徳 喜谷 新規な白金錯体
US4225529A (en) * 1977-10-19 1980-09-30 Johnson, Matthey & Co., Limited Compositions containing platinum
NL7810433A (nl) * 1977-10-19 1979-04-23 Johnson Matthey Co Ltd Nieuwe platinaverbindingen.
SE7903359L (sv) * 1978-04-20 1979-10-21 Johnson Matthey Co Ltd Kompositioner innehallande platina
US4284579A (en) * 1979-07-17 1981-08-18 The United States Of America As Represented By The Of The Department Of Health & Human Services (N-Phosphonacetyl-L-aspartato)(1,2-diaminocyclchexane)platinum(II) or alkali metal salt

Also Published As

Publication number Publication date
FI811314A7 (fi) 1981-10-30
PT72941A (fr) 1981-05-01
MA19131A1 (fr) 1981-12-31
PL230896A1 (enEXAMPLES) 1982-01-04
AR226354A1 (es) 1982-06-30
EP0039272A2 (fr) 1981-11-04
ES502411A0 (es) 1982-04-01
IT8167555A0 (it) 1981-04-23
ZW8681A1 (en) 1981-07-08
RO82032B (ro) 1984-01-30
OA06797A (fr) 1982-12-31
IE810925L (en) 1981-10-29
FR2481289A1 (fr) 1981-10-30
AU6978681A (en) 1981-11-05
NZ196803A (en) 1983-12-16
FI811314L (fi) 1981-10-30
CA1171425A (en) 1984-07-24
PT72941B (fr) 1982-03-30
EP0039272B1 (fr) 1984-04-18
MC1391A1 (fr) 1982-04-27
ES8203324A1 (es) 1982-04-01
ATA191981A (de) 1983-01-15
LU83325A1 (fr) 1981-07-24
BE888367A (fr) 1981-07-31
AT372072B (de) 1983-08-25
IE51197B1 (en) 1986-10-29
NO811449L (no) 1981-10-30
GB2077720B (en) 1983-09-07
DE3163162D1 (en) 1984-10-04
IT1146749B (it) 1986-11-19
GR75598B (enEXAMPLES) 1984-08-01
DK188481A (da) 1981-10-30
FR2481289B1 (fr) 1985-06-14
IL62615A0 (en) 1981-06-29
US4452812A (en) 1984-06-05
YU102581A (en) 1983-09-30
RO82032A (ro) 1984-01-14
PL128539B1 (en) 1984-02-29
ZA812474B (en) 1982-05-26
EP0039272A3 (en) 1982-05-05
JPS595599B2 (ja) 1984-02-06
JPS572296A (en) 1982-01-07
DD158777A5 (de) 1983-02-02
GB2077720A (en) 1981-12-23

Similar Documents

Publication Publication Date Title
JO1176B1 (en) Organic platinum compound, method of preparation and use in the treatment of malignant tumors
ES8205231A1 (es) Procedimiento para preparar complejos de platino (iv)-diami-na
DE2862002D1 (en) Cis-platinum (ii) complexes of 1,2-diamino-cyclohexane and pharmaceutical composition containing them
IL57717A (en) Platinum-diamine complexes,a method for the preparation thereof,a method for the preparation of a medicine using such a platinum-diamine complex for the treatment of cancer as well as a medicine thus formed
EP0417870A3 (en) Chelates for complexation of radioactive isotopes, their metal complexes and their use in diagnosis and therapy
IL127352A0 (en) Pyridyl alkene- and pyridyl alkine-acid amides as cytostatics and immunosupressives
GEP19960468B (en) Method of producing derivatives of isoquinoline
AU559983B2 (en) Platinum complexes, treatment of cancer
GB8810173D0 (en) Pharmaceutical compositions with anti-cancer activity & method for treatment of cancer
FR2534907B1 (fr) Complexes diamine-platine, un procede pour leur preparation, un procede pour la preparation d'une composition medicinale utilisant un tel complexe diamine platine pour le traitement du cancer ainsi que la composition ainsi formee
HUT51594A (en) Process for production of celates and their complexes containing ortolizating functional groups, compositions containing such active substances and process for production of conjugates consisting of one complex and linked to it antibody or fragment of antibody
ZA85755B (en) Antitumor pharmaceutical compositions and methods for treating tumors employing(a,w-bis(dissubstitutedphosphino)hydrocarbon)digold(i),digold(iii),disilver(i)and dicopper(i)derivatives
ATE71630T1 (de) 1,2-diaminocyclohexan-platin-komplexe mit antitumor-wirkung.
DE3378524D1 (en) Anti-cancer drugs comprising platinum complexes
ES8604248A1 (es) Un procedimiento para la preparacion de complejos de amino- antracenodionas-platino
ES2012547A6 (es) Procedimiento para preparar una composicion farmaceutica que contiene metaloporfirinas.
DK93585A (da) Omega-aryl-alkylthienyl-forbindelser, fremgangsmaade til fremstillingaf disse forbindelser og farmaceutiske praeparater indeholdende disse forbindelser
DE69232852D1 (de) Verwendung von topotecan in der behandlung von nichtkleinzelligen lungenkarzinomen
DE59209351D1 (de) Carboplatin oder Lobaplatin ENTHALTENDE ZUBEREITUNGEN ZUR ANTITUMORTHERAPIE UND/ODER STIMULIERUNG DES HÄMATOPOETISCHEN SYSTEMS
SE8103404L (sv) Tennforeningar, sett att framstella dem, sett att framstella ett lekemedelspreparat under anvendning av en dylik tennforening for behandling av cancer samt det pa sa sett erhallna lekemedelspreparatet
FR2377393A1 (fr) Nouveau complexe de titane trivalent et de cuivre divalent de l'acide ascorbique utile notamment pour le traitement des maladies comportant des anomalies de formule sanguine, et son procede de preparation
GB2006776A (en) Platinum (II) Complexes with Amines
CA987591A (en) Bronchodilatory compositions containing quinazoline derivatives for inhalation therapy
Spasskaya Experimental data concerning the isopropyl ester of αN-nicotinoyl-sarcolysin
Chottard Metal ions biological systems, vol. 10, carcinogenicity and metal ions: Edited by Helmut Sigel, Published by Marcel Dekker, New York, 1980; pp. 381; Price SF 155.