ITRM20040327A1 - Uso della acetil l-carnitina per la preparazione di un medicamento per il trattamento del dolore neuropatico in pazienti diabetici. - Google Patents
Uso della acetil l-carnitina per la preparazione di un medicamento per il trattamento del dolore neuropatico in pazienti diabetici.Info
- Publication number
- ITRM20040327A1 ITRM20040327A1 IT000327A ITRM20040327A ITRM20040327A1 IT RM20040327 A1 ITRM20040327 A1 IT RM20040327A1 IT 000327 A IT000327 A IT 000327A IT RM20040327 A ITRM20040327 A IT RM20040327A IT RM20040327 A1 ITRM20040327 A1 IT RM20040327A1
- Authority
- IT
- Italy
- Prior art keywords
- carnitine
- medication
- acetyl
- preparation
- treatment
- Prior art date
Links
- RDHQFKQIGNGIED-MRVPVSSYSA-N O-acetyl-L-carnitine Chemical compound CC(=O)O[C@H](CC([O-])=O)C[N+](C)(C)C RDHQFKQIGNGIED-MRVPVSSYSA-N 0.000 title 1
- 206010012601 diabetes mellitus Diseases 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 208000004296 neuralgia Diseases 0.000 title 1
- 208000021722 neuropathic pain Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Endocrinology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
Priority Applications (15)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000327A ITRM20040327A1 (it) | 2004-07-01 | 2004-07-01 | Uso della acetil l-carnitina per la preparazione di un medicamento per il trattamento del dolore neuropatico in pazienti diabetici. |
| US10/969,217 US20060004095A1 (en) | 2004-07-01 | 2004-10-21 | Use of acetyl L-carnitine for the preparation of a medicine for the treatment of neuropathic pain in diabetic patients |
| KR1020077000584A KR101176347B1 (ko) | 2004-07-01 | 2005-04-05 | 당뇨병 환자의 신경병 통증 치료용 약제의 제조를 위한아세틸 엘 카르니틴의 용도 |
| ES05730316.6T ES2532497T3 (es) | 2004-07-01 | 2005-04-05 | Uso de acetil-L-carnitina para la preparación de un medicamento para el tratamiento del dolor neuropático en pacientes diabéticos |
| US11/570,484 US20070213408A1 (en) | 2004-07-01 | 2005-04-05 | Use of Acetyl L-Carnitine for the Preparation of a Medicine for the Treatment of Neuropathic Pain in Diabetic Patients |
| MXPA06014907A MXPA06014907A (es) | 2004-07-01 | 2005-04-05 | Uso de acetil l-carnitina para preparacion de medicina para tratamiento de dolor neuropatico en pacientes diabeticos. |
| SI200531946T SI1761257T1 (sl) | 2004-07-01 | 2005-04-05 | Uporaba acetil-L-karnitina za pripravo zdravila za zdravljenje nevropatske bolečine pri diabetičnih bolnikih |
| EP05730316.6A EP1761257B1 (en) | 2004-07-01 | 2005-04-05 | Use of acetyl l-carnitine for the preparation of a medicine for the treatment of neuropathic pain in diabetic patients |
| PL05730316T PL1761257T3 (pl) | 2004-07-01 | 2005-04-05 | Zastosowanie acetylo-L-karnityny podczas przygotowania leku do leczenia bólu neuropatycznego u pacjentów cukrzycowych |
| CA2570268A CA2570268C (en) | 2004-07-01 | 2005-04-05 | Use of acetyl l-carnitine for the preparation of a medicine for the treatment of neuropathic pain in diabetic patients |
| PCT/EP2005/003557 WO2006002698A1 (en) | 2004-07-01 | 2005-04-05 | Use of acetyl l-carnitine for the preparation of a medicine for the treatment of neuropathic pain in diabetic patients |
| PT57303166T PT1761257E (pt) | 2004-07-01 | 2005-04-05 | O uso de acetil l-carnitina para a preparação de um medicamento para o tratamento de dor neuropática em pacientes diabéticos |
| JP2007519628A JP5519907B2 (ja) | 2004-07-01 | 2005-04-05 | 糖尿病患者における神経因性疼痛の治療用医薬の調製のためのアセチルl−カルニチンの使用 |
| DK05730316T DK1761257T3 (en) | 2004-07-01 | 2005-04-05 | Use of acetyl L-carnitine in the manufacture of a medicament for the treatment of neuropathic pain in diabetic patients |
| CY20151100283T CY1116171T1 (el) | 2004-07-01 | 2015-03-23 | Χρηση ακετυλο-l-καρνιτινης για την παρασκευη φαρμακου για τη θεραπευτικη αγωγη του νευροπαθητικου πονου σε διαβητικους ασθενεις |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000327A ITRM20040327A1 (it) | 2004-07-01 | 2004-07-01 | Uso della acetil l-carnitina per la preparazione di un medicamento per il trattamento del dolore neuropatico in pazienti diabetici. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ITRM20040327A1 true ITRM20040327A1 (it) | 2004-10-01 |
Family
ID=34965656
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT000327A ITRM20040327A1 (it) | 2004-07-01 | 2004-07-01 | Uso della acetil l-carnitina per la preparazione di un medicamento per il trattamento del dolore neuropatico in pazienti diabetici. |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US20060004095A1 (enExample) |
| EP (1) | EP1761257B1 (enExample) |
| JP (1) | JP5519907B2 (enExample) |
| KR (1) | KR101176347B1 (enExample) |
| CA (1) | CA2570268C (enExample) |
| CY (1) | CY1116171T1 (enExample) |
| DK (1) | DK1761257T3 (enExample) |
| ES (1) | ES2532497T3 (enExample) |
| IT (1) | ITRM20040327A1 (enExample) |
| MX (1) | MXPA06014907A (enExample) |
| PL (1) | PL1761257T3 (enExample) |
| PT (1) | PT1761257E (enExample) |
| SI (1) | SI1761257T1 (enExample) |
| WO (1) | WO2006002698A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU230002B1 (en) * | 2000-12-15 | 2015-04-28 | Sigma Tau Ind Farmaceuti | Use of l-carnitine for preparation of compositions for stabilizing the proteins |
| US8173618B2 (en) * | 2003-07-25 | 2012-05-08 | University Of Massachusetts | Formulations for reducing neuronal degeneration |
| US8597640B2 (en) * | 2007-10-31 | 2013-12-03 | University Of Massachusetts Lowell | Over-the-counter vitamin/nutriceutical formulation that provides neuroprotection and maintains or improves cognitive performance in alzheimer's disease and normal aging |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1133010B (it) * | 1980-05-15 | 1986-07-09 | Sigma Tau Ind Farmaceuti | Metodo terapuetico per il trattamento del diabete mellito a insorgenza giovanile e composizione farmaceutica per tale metodo |
| IT1196564B (it) * | 1986-08-04 | 1988-11-16 | Sigma Tau Ind Farmaceuti | Impiego di acetil l-carnitina nel trattamento terapeutico delle neuropatie periferiche |
| IT1224842B (it) * | 1988-12-27 | 1990-10-24 | Sigma Tau Ind Farmaceuti | Uso di derivati della l-carnitina nel trattamento terapeutico delle alterazioni degenerative del sistema nervoso |
| IT1263004B (it) * | 1992-10-08 | 1996-07-23 | Sigma Tau Ind Farmaceuti | Impiego della l-carnitina e acil l-carnitine nel trattamento a lungo termine di pazienti diabetici non insulino-dipendenti. |
| US5827886A (en) * | 1997-05-07 | 1998-10-27 | Thione International, Inc. | Composition for relief of arthritis-induced symptoms |
| IT1294227B1 (it) * | 1997-08-01 | 1999-03-24 | Sigma Tau Ind Farmaceuti | Composizione farmaceutica contenente l-carnitina o una alcanoil l-carnitina e alcoli alifatici a lunga catena utile per la prevenzione |
| IT1306178B1 (it) * | 1999-07-27 | 2001-05-30 | Sigma Tau Ind Farmaceuti | Uso della l-carnitina e dei suoi alcanoil derivati per la preparazionedi un medicamento utile nel trattamento del paziente affetto da |
| ITRM20010294A1 (it) * | 2001-05-29 | 2002-11-29 | Sigma Tau Ind Farmaceuti | Uso della acetil l-carnetina in associazione con la biotina per il trattamento di pazienti affetti da diabete mellito di tipo ii insulino re |
-
2004
- 2004-07-01 IT IT000327A patent/ITRM20040327A1/it unknown
- 2004-10-21 US US10/969,217 patent/US20060004095A1/en not_active Abandoned
-
2005
- 2005-04-05 SI SI200531946T patent/SI1761257T1/sl unknown
- 2005-04-05 PT PT57303166T patent/PT1761257E/pt unknown
- 2005-04-05 KR KR1020077000584A patent/KR101176347B1/ko not_active Expired - Fee Related
- 2005-04-05 PL PL05730316T patent/PL1761257T3/pl unknown
- 2005-04-05 WO PCT/EP2005/003557 patent/WO2006002698A1/en not_active Ceased
- 2005-04-05 JP JP2007519628A patent/JP5519907B2/ja not_active Expired - Fee Related
- 2005-04-05 CA CA2570268A patent/CA2570268C/en not_active Expired - Lifetime
- 2005-04-05 US US11/570,484 patent/US20070213408A1/en not_active Abandoned
- 2005-04-05 DK DK05730316T patent/DK1761257T3/en active
- 2005-04-05 ES ES05730316.6T patent/ES2532497T3/es not_active Expired - Lifetime
- 2005-04-05 EP EP05730316.6A patent/EP1761257B1/en not_active Expired - Lifetime
- 2005-04-05 MX MXPA06014907A patent/MXPA06014907A/es not_active Application Discontinuation
-
2015
- 2015-03-23 CY CY20151100283T patent/CY1116171T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2570268C (en) | 2013-10-15 |
| JP5519907B2 (ja) | 2014-06-11 |
| SI1761257T1 (sl) | 2015-04-30 |
| EP1761257A1 (en) | 2007-03-14 |
| ES2532497T3 (es) | 2015-03-27 |
| DK1761257T3 (en) | 2015-03-23 |
| PT1761257E (pt) | 2015-04-14 |
| KR20070042963A (ko) | 2007-04-24 |
| MXPA06014907A (es) | 2007-03-21 |
| CA2570268A1 (en) | 2006-01-12 |
| CY1116171T1 (el) | 2017-02-08 |
| WO2006002698A1 (en) | 2006-01-12 |
| JP2008505134A (ja) | 2008-02-21 |
| EP1761257B1 (en) | 2014-12-31 |
| US20060004095A1 (en) | 2006-01-05 |
| KR101176347B1 (ko) | 2012-08-24 |
| PL1761257T3 (pl) | 2015-06-30 |
| US20070213408A1 (en) | 2007-09-13 |
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