ITMI971544A0 - - Google Patents

Info

Publication number
ITMI971544A0
ITMI971544A0 ITMI971544A ITMI971544A ITMI971544A0 IT MI971544 A0 ITMI971544 A0 IT MI971544A0 IT MI971544 A ITMI971544 A IT MI971544A IT MI971544 A ITMI971544 A IT MI971544A IT MI971544 A0 ITMI971544 A0 IT MI971544A0
Authority
IT
Italy
Application number
ITMI971544A
Other languages
Italian (it)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of ITMI971544A0 publication Critical patent/ITMI971544A0/it
Priority to IT97MI001544A priority Critical patent/IT1292437B1/it
Priority to EP98936398A priority patent/EP0994881B1/en
Priority to PCT/EP1998/003969 priority patent/WO1999001459A1/en
Priority to DE69808093T priority patent/DE69808093T2/de
Priority to US09/445,470 priority patent/US6271375B1/en
Priority to IL13324998A priority patent/IL133249A/xx
Priority to JP50630899A priority patent/JP4128633B2/ja
Priority to CZ19994774A priority patent/CZ293277B6/cs
Priority to ES98936398T priority patent/ES2182349T3/es
Priority to AT98936398T priority patent/ATE224395T1/de
Priority to CA002294609A priority patent/CA2294609C/en
Priority to HU0004227A priority patent/HU226471B1/hu
Publication of ITMI971544A1 publication Critical patent/ITMI971544A1/it
Application granted granted Critical
Publication of IT1292437B1 publication Critical patent/IT1292437B1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
    • C07F3/02—Magnesium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT97MI001544A 1997-06-30 1997-06-30 Processo di orto-metallazione utile per la sintesi di 1 - tetrazol- 5-il) benzeni 2-sostituiti IT1292437B1 (it)

Priority Applications (12)

Application Number Priority Date Filing Date Title
IT97MI001544A IT1292437B1 (it) 1997-06-30 1997-06-30 Processo di orto-metallazione utile per la sintesi di 1 - tetrazol- 5-il) benzeni 2-sostituiti
JP50630899A JP4128633B2 (ja) 1997-06-30 1998-06-29 ２−置換−１−（テトラゾール−５−イル）ベンゼン合成のためのオルトメタル化方法
ES98936398T ES2182349T3 (es) 1997-06-30 1998-06-29 Procedimiento de orto-metalizacion para la sintesis de 1-(tetrazol-5-il)bencenos sustituidos en la posicion 2.
DE69808093T DE69808093T2 (de) 1997-06-30 1998-06-29 Verfahren zur herstellung von 2-substituierten 1-(tetrazol-5-yl)benzenverbindungen durch ortho-metallierung
US09/445,470 US6271375B1 (en) 1997-06-30 1998-06-29 Ortho-metalation process for the synthesis of 2-substituted-1-(tetrazol-5-yl)benzenes
IL13324998A IL133249A (en) 1997-06-30 1998-06-29 Ortho-metalation process for the synthesis of 2-substituted-1- (tetrazol-5-yl) benzenes
EP98936398A EP0994881B1 (en) 1997-06-30 1998-06-29 Ortho-metalation process for the synthesis of 2-substituted-1-(tetrazol-5-yl)benzenes
CZ19994774A CZ293277B6 (cs) 1997-06-30 1998-06-29 Způsob přímé ortho-metalace
PCT/EP1998/003969 WO1999001459A1 (en) 1997-06-30 1998-06-29 Ortho-metalation process for the synthesis of 2-substituted-1-(tetrazol-5-yl)benzenes
AT98936398T ATE224395T1 (de) 1997-06-30 1998-06-29 Verfahren zur herstellung von 2-substituierten 1- (tetrazol-5-yl)benzenverbindungen durch ortho- metallierung
CA002294609A CA2294609C (en) 1997-06-30 1998-06-29 Ortho-metalation process for the synthesis of 2-substituted-1-(tetrazol-5-yl)benzenes
HU0004227A HU226471B1 (en) 1997-06-30 1998-06-29 Direct ortho-metalation process for the synthesis of 5-(2-substituted-phenyl)-tetrazol derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT97MI001544A IT1292437B1 (it) 1997-06-30 1997-06-30 Processo di orto-metallazione utile per la sintesi di 1 - tetrazol- 5-il) benzeni 2-sostituiti

Publications (3)

Publication Number Publication Date
ITMI971544A0 true ITMI971544A0 (en:Method) 1997-06-30
ITMI971544A1 ITMI971544A1 (it) 1998-12-30
IT1292437B1 IT1292437B1 (it) 1999-02-08

Family

ID=11377464

Family Applications (1)

Application Number Title Priority Date Filing Date
IT97MI001544A IT1292437B1 (it) 1997-06-30 1997-06-30 Processo di orto-metallazione utile per la sintesi di 1 - tetrazol- 5-il) benzeni 2-sostituiti

Country Status (12)

Country Link
US (1) US6271375B1 (en:Method)
EP (1) EP0994881B1 (en:Method)
JP (1) JP4128633B2 (en:Method)
AT (1) ATE224395T1 (en:Method)
CA (1) CA2294609C (en:Method)
CZ (1) CZ293277B6 (en:Method)
DE (1) DE69808093T2 (en:Method)
ES (1) ES2182349T3 (en:Method)
HU (1) HU226471B1 (en:Method)
IL (1) IL133249A (en:Method)
IT (1) IT1292437B1 (en:Method)
WO (1) WO1999001459A1 (en:Method)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ514855A (en) 1999-04-28 2004-01-30 Takeda Chemical Industries Ltd Preventives / remedies / progression inhibitors for simplex retinopathy or preproliferating retinopathy
BR0312968A (pt) 2002-07-26 2005-06-14 Pharmacia Groningen Bv Método e dispositivo para manipulação de uma lente intraocular
ATE398121T1 (de) * 2003-01-16 2008-07-15 Teva Pharma Neue synthese von irbesartan
US7199144B2 (en) * 2003-04-21 2007-04-03 Teva Pharmaceuticals Industries, Ltd. Process for the preparation of valsartan and intermediates thereof
EP1950204A1 (en) 2003-03-17 2008-07-30 Teva Pharmaceutical Industries Ltd. Amorphous form of valsartan
CA2519490A1 (en) * 2003-03-17 2004-09-30 Teva Pharmaceutical Industries Ltd Polymorphis of valsartan
EP1556363A2 (en) * 2003-04-21 2005-07-27 Teva Pharmaceutical Industries Limited Process for the preparation of valsartan and intermediates thereof
WO2004094392A1 (en) * 2003-04-21 2004-11-04 Teva Pharmaceutical Industries Ltd. Process for the preparation of valsartan
DE602004010530T2 (de) * 2003-08-08 2008-11-13 Dipharma Francis S.R.L. Verfahren zur herstellung von phenyltetrazolderivaten
WO2005049587A1 (en) * 2003-11-21 2005-06-02 Ranbaxy Laboratories Limited Process for preparation of biphenyl tetrazole
ES2282062T1 (es) 2004-06-04 2007-10-16 Teva Pharmaceutical Industries Ltd. Composicion farmaceutica que contiene irbesartan.
WO2006067216A2 (en) * 2004-12-22 2006-06-29 Enantia, S. L. Intermediate compounds for the preparation of an angiotensin ii receptor and process for the preparation of valsartan
ATE397592T1 (de) * 2004-12-22 2008-06-15 Algry Quimica S L Zwischenprodukte für die herstellung von antagonisten des angiotensin-ii-rezeptors
WO2007005967A2 (en) * 2005-07-05 2007-01-11 Teva Pharmaceutical Industries Ltd. Process for preparing valsartan
US20090304797A1 (en) * 2006-06-23 2009-12-10 Tarur Venkatasubramanian Radha Process for the Preparation of Micronized Valsartan
EP2090567A3 (en) 2008-02-13 2011-06-01 Ranbaxy Laboratories Limited Processes for the preparation of intermediates of valsartan
WO2009125416A2 (en) * 2008-04-07 2009-10-15 Hetero Research Foundation Process for preparation of valsartan intermediate
WO2012056294A1 (en) 2010-10-29 2012-05-03 Jubilant Life Sciences Ltd. An improved process for the preparation of n-pentanoyl-n-[[2'-(1h-tetrazol-5-yi)[1,1'-biphenyl]-4-yi]methyl]-l-valine
WO2018002673A1 (en) 2016-07-01 2018-01-04 N4 Pharma Uk Limited Novel formulations of angiotensin ii receptor antagonists
US12365654B2 (en) 2019-12-02 2025-07-22 Harman Finochem Limited Process for the preparation of highly pure valsartan

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5039814A (en) * 1990-05-02 1991-08-13 Merck & Co., Inc. Ortho-lithiation process for the synthesis of 2-substituted 1-(tetrazol-5-yl)benzenes
US5149699A (en) 1991-10-24 1992-09-22 American Home Products Corporation Substituted pyridopyrimidines useful as antgiotensin II antagonists
US5256654A (en) 1991-10-24 1993-10-26 American Home Products Corporation Substituted pyrrolopyrimidines, azepinopyrimidines and pyridopyrimidines useful as angiotensin II antagonists
TW226375B (en:Method) * 1991-10-24 1994-07-11 American Home Prod
EP0550313A1 (fr) 1991-12-30 1993-07-07 Synthelabo Nouveaux dérivés de 2-(tétrazol-5-yl)-(1,1'-biphényle), leur préparation et leur utilisation comme intermédiaires de synthèse
US5310929A (en) * 1992-08-06 1994-05-10 E. I. Du Pont De Nemours And Company Prodrugs of imidazole carboxylic acids as angiotensin II receptor antagonists
FR2696746B1 (fr) 1992-10-12 1994-11-18 Synthelabo Dérivés de l'acide benzèneborinique, leur préparation et leur utilisation comme intermédiaires de synthèse.
WO1996040684A1 (en) * 1995-06-07 1996-12-19 American Home Products Corporation Process for preparation of biphenyl derivatives
US5760220A (en) 1995-06-07 1998-06-02 American Home Products Corporation Process for preparation of biphenyl derivatives

Also Published As

Publication number Publication date
CA2294609A1 (en) 1999-01-14
CA2294609C (en) 2008-08-19
HUP0004227A3 (en) 2003-03-28
IT1292437B1 (it) 1999-02-08
HU226471B1 (en) 2008-12-29
CZ293277B6 (cs) 2004-03-17
HUP0004227A2 (hu) 2001-06-28
ITMI971544A1 (it) 1998-12-30
ATE224395T1 (de) 2002-10-15
DE69808093T2 (de) 2003-06-05
EP0994881B1 (en) 2002-09-18
JP4128633B2 (ja) 2008-07-30
WO1999001459A1 (en) 1999-01-14
US6271375B1 (en) 2001-08-07
IL133249A0 (en) 2001-04-30
ES2182349T3 (es) 2003-03-01
DE69808093D1 (de) 2002-10-24
CZ477499A3 (cs) 2000-07-12
JP2002510314A (ja) 2002-04-02
IL133249A (en) 2003-12-10
EP0994881A1 (en) 2000-04-26

Similar Documents

Publication Publication Date Title
BE2018C032I2 (en:Method)
ITTO970518A0 (en:Method)
CH0944937H2 (en:Method)
ITMI971544A0 (en:Method)
IN190821B (en:Method)
ITMI971006A0 (en:Method)
IN190966B (en:Method)
ITMI970972A0 (en:Method)
BE2013C047I2 (en:Method)
BR9701757A (en:Method)
BR9700653A (en:Method)
ECSDI970456S (en:Method)
IN191642B (en:Method)
ITPD970129A0 (en:Method)
ITMI971331A0 (en:Method)
CN3058531S (en:Method)
CN3058462S (en:Method)
BY4238C1 (en:Method)
BY4349C1 (en:Method)
CN3058984S (en:Method)
CN3053500S (en:Method)
CN3053170S (en:Method)
CN3055179S (en:Method)
CN3058025S (en:Method)
CN3058320S (en:Method)

Legal Events

Date Code Title Description
0001 Granted