ITMI951560A0 - Substrati fluorogenici suscettibili di fotoattivazione previa trasformazione per via enzimatica atti alla diagnosi ed alla terapia fotodinamica dei tumori - Google Patents

Substrati fluorogenici suscettibili di fotoattivazione previa trasformazione per via enzimatica atti alla diagnosi ed alla terapia fotodinamica dei tumori

Info

Publication number
ITMI951560A0
ITMI951560A0 ITMI951560A ITMI951560A ITMI951560A0 IT MI951560 A0 ITMI951560 A0 IT MI951560A0 IT MI951560 A ITMI951560 A IT MI951560A IT MI951560 A ITMI951560 A IT MI951560A IT MI951560 A0 ITMI951560 A0 IT MI951560A0
Authority
IT
Italy
Prior art keywords
photoactivation
tumors
diagnosis
photodynamic therapy
fluorogenic substrates
Prior art date
Application number
ITMI951560A
Other languages
English (en)
Original Assignee
Consiglio Nazionale Ricerche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Consiglio Nazionale Ricerche filed Critical Consiglio Nazionale Ricerche
Priority to ITMI951560A priority Critical patent/IT1275571B/it
Publication of ITMI951560A0 publication Critical patent/ITMI951560A0/it
Priority to CA002227212A priority patent/CA2227212A1/en
Priority to AU67351/96A priority patent/AU6735196A/en
Priority to EP96927559A priority patent/EP0839051A1/en
Priority to US09/011,347 priority patent/US6036941A/en
Priority to PCT/EP1996/003201 priority patent/WO1997003697A2/en
Publication of ITMI951560A1 publication Critical patent/ITMI951560A1/it
Application granted granted Critical
Publication of IT1275571B publication Critical patent/IT1275571B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0036—Porphyrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0041—Xanthene dyes, used in vivo, e.g. administered to a mice, e.g. rhodamines, rose Bengal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0052—Small organic molecules

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
ITMI951560A 1995-07-19 1995-07-19 Substrati fluorogenici suscettibili di fotoattivazione previa trasformazione per via enzimatica atti alla diagnosi ed alla terapia fotodinamica dei tumori IT1275571B (it)

Priority Applications (6)

Application Number Priority Date Filing Date Title
ITMI951560A IT1275571B (it) 1995-07-19 1995-07-19 Substrati fluorogenici suscettibili di fotoattivazione previa trasformazione per via enzimatica atti alla diagnosi ed alla terapia fotodinamica dei tumori
CA002227212A CA2227212A1 (en) 1995-07-19 1996-07-19 Fluorogenic substrates for diagnosis and photodynamic treatment of tumours
AU67351/96A AU6735196A (en) 1995-07-19 1996-07-19 Fluorogenic substrates for diagnosis and photodynamic treatment of tumours
EP96927559A EP0839051A1 (en) 1995-07-19 1996-07-19 Fluorogenic substrates for diagnosis and photodynamic treatment of tumours
US09/011,347 US6036941A (en) 1995-07-19 1996-07-19 Fluorogenic substrates for diagnosis and photodynamic treatment of tumors
PCT/EP1996/003201 WO1997003697A2 (en) 1995-07-19 1996-07-19 Fluorogenic substrates for diagnosis and photodynamic treatment of tumours

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI951560A IT1275571B (it) 1995-07-19 1995-07-19 Substrati fluorogenici suscettibili di fotoattivazione previa trasformazione per via enzimatica atti alla diagnosi ed alla terapia fotodinamica dei tumori

Publications (3)

Publication Number Publication Date
ITMI951560A0 true ITMI951560A0 (it) 1995-07-19
ITMI951560A1 ITMI951560A1 (it) 1997-01-19
IT1275571B IT1275571B (it) 1997-08-07

Family

ID=11372009

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI951560A IT1275571B (it) 1995-07-19 1995-07-19 Substrati fluorogenici suscettibili di fotoattivazione previa trasformazione per via enzimatica atti alla diagnosi ed alla terapia fotodinamica dei tumori

Country Status (6)

Country Link
US (1) US6036941A (it)
EP (1) EP0839051A1 (it)
AU (1) AU6735196A (it)
CA (1) CA2227212A1 (it)
IT (1) IT1275571B (it)
WO (1) WO1997003697A2 (it)

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US6493570B1 (en) * 1998-11-02 2002-12-10 Photogen, Inc. Method for improved imaging and photodynamic therapy
US6331286B1 (en) * 1998-12-21 2001-12-18 Photogen, Inc. Methods for high energy phototherapeutics
US7390668B2 (en) 1996-10-30 2008-06-24 Provectus Pharmatech, Inc. Intracorporeal medicaments for photodynamic treatment of disease
US8974363B2 (en) * 1997-12-11 2015-03-10 Provectus Pharmatech, Inc. Topical medicaments and methods for photodynamic treatment of disease
US7648695B2 (en) 1998-08-06 2010-01-19 Provectus Pharmatech, Inc. Medicaments for chemotherapeutic treatment of disease
US20090117199A1 (en) * 1998-08-06 2009-05-07 Scott Timothy C Method of treatment of cancer
US8557298B2 (en) * 1998-08-06 2013-10-15 Provectus Pharmatech, Inc. Medicaments for chemotherapeutic treatment of disease
JP2002522111A (ja) * 1998-08-06 2002-07-23 フォトゲン インク 疾患の標的局所治療の改善された方法
US6986740B2 (en) * 1998-11-02 2006-01-17 Xantech Pharmaceuticals, Inc. Ultrasound contrast using halogenated xanthenes
US8470296B2 (en) 1998-12-21 2013-06-25 Provectus Pharmatech, Inc. Intracorporeal medicaments for high energy phototherapeutic treatment of disease
US7384623B1 (en) 1998-12-21 2008-06-10 Provectus Pharmatech, Inc. High energy phototherapeutic agents
JP2002534218A (ja) * 1999-01-15 2002-10-15 ライト サイエンシーズ コーポレイション 非侵襲性の脈管療法
CA2358662A1 (en) * 1999-01-15 2000-07-20 James Chen Therapeutic compositions for metabolic bone disorders or bone metastases
US6602274B1 (en) * 1999-01-15 2003-08-05 Light Sciences Corporation Targeted transcutaneous cancer therapy
EP1040825A1 (en) * 1999-03-11 2000-10-04 K.U. Leuven Research & Development Means for diagnosing bladder carcinoma
US20030114434A1 (en) * 1999-08-31 2003-06-19 James Chen Extended duration light activated cancer therapy
US7897140B2 (en) 1999-12-23 2011-03-01 Health Research, Inc. Multi DTPA conjugated tetrapyrollic compounds for phototherapeutic contrast agents
EP1267935A2 (en) * 2000-01-12 2003-01-02 Light Sciences Corporation Novel treatment for eye disease
EP1283728A2 (en) * 2000-05-23 2003-02-19 Amersham Health AS Contrast agents
GB0113899D0 (en) 2001-06-07 2001-08-01 Photocure Asa Photodynamic therapy lamp
JP2005527493A (ja) * 2002-01-23 2005-09-15 ライト サイエンシーズ コーポレイション 光線力学療法のためのシステムおよび方法
CN1389110A (zh) * 2002-05-10 2003-01-08 张红雨 苝醌衍生物光敏生物杀菌剂及其制法
EP1517684B1 (en) 2002-06-27 2009-07-22 Health Research, Inc. Fluorinated chlorin and bacteriochlorin photosensitizers for photodynamic therapy
GB0215534D0 (en) * 2002-07-04 2002-08-14 Ecole Polytech Selective photochemotherapy using oligonucleotide targeting agents
US20050106100A1 (en) * 2003-09-03 2005-05-19 Harris Thomas D. Compounds containing matrix metalloproteinase substrates and methods of their use
US20060067889A1 (en) * 2004-09-27 2006-03-30 Light Sciences Corporation Singlet oxygen photosensitizers activated by target binding enhancing the selectivity of targeted PDT agents
US20070014721A1 (en) * 2005-06-30 2007-01-18 Harris Thomas D Hydrazide conjugates as imaging agents
US20100016208A1 (en) * 2005-11-15 2010-01-21 The General Hospital Corporation Photoactivatable antimicrobial agents
WO2007072800A1 (ja) * 2005-12-19 2007-06-28 The University Of Tokyo 光増感用化合物
US9358292B2 (en) * 2007-04-08 2016-06-07 Immunolight, Llc Methods and systems for treating cell proliferation disorders
US20090104212A1 (en) * 2007-08-06 2009-04-23 Immunolight Methods and systems for treating cell proliferation disorders using two-photon simultaneous absorption
TWI574712B (zh) * 2008-02-21 2017-03-21 伊穆諾萊特公司 利用電漿子增強之光譜療法（ｐｅｐｓｔ）及激子-電漿增強之光療法（ｅｐｅｐ）治療細胞增生病症之組合物及產生自體疫苗之系統
WO2013009688A1 (en) 2011-07-08 2013-01-17 Bourke Frederic A Phosphors and scintillators for light stimulation within a medium
CN113274496A (zh) * 2008-04-04 2021-08-20 免疫之光有限责任公司 用于原位光生物调节的非侵入性系统和方法
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KR101385196B1 (ko) 2012-05-17 2014-04-14 주식회사 유니크메디케어 광 조사를 이용한 광감각제―펩타이드를 유효성분으로 포함하는 발모 개선 또는 촉진용 조성물 및 이를 이용한 방법
US9371555B2 (en) 2012-06-01 2016-06-21 Concordia Laboratories Inc. Lighting systems and methods of using lighting systems for in vitro potency assay for photofrin
WO2013192521A1 (en) 2012-06-22 2013-12-27 The General Hospital Corporation β-LACTAMASE TARGETED PHOTOSENSITIZER FOR PESTICIDE AND PEST DETECTION
WO2014139012A1 (en) 2013-03-15 2014-09-18 Suncor Energy Inc. Herbicidal compositions
ES2894912T3 (es) 2014-07-24 2022-02-16 Univ Health Network Recopilación y análisis de datos con fines de diagnóstico

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Also Published As

Publication number Publication date
WO1997003697A3 (en) 1997-04-10
CA2227212A1 (en) 1997-02-06
EP0839051A1 (en) 1998-05-06
IT1275571B (it) 1997-08-07
ITMI951560A1 (it) 1997-01-19
WO1997003697A2 (en) 1997-02-06
AU6735196A (en) 1997-02-18
US6036941A (en) 2000-03-14

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