ITMI932343A1 - Procedimento per l'isolamento e la purificazione di mevinolina - Google Patents

Procedimento per l'isolamento e la purificazione di mevinolina

Info

Publication number
ITMI932343A1
ITMI932343A1 IT002343A ITMI932343A ITMI932343A1 IT MI932343 A1 ITMI932343 A1 IT MI932343A1 IT 002343 A IT002343 A IT 002343A IT MI932343 A ITMI932343 A IT MI932343A IT MI932343 A1 ITMI932343 A1 IT MI932343A1
Authority
IT
Italy
Prior art keywords
mevinolina
isolation
purification procedure
purification
procedure
Prior art date
Application number
IT002343A
Other languages
English (en)
Inventor
Gabor Ambrus
Attila Andor
Ilona Bagdi
Janos Balint
Lajos Deak
Etelka Deli
Laszlo Eszenyi
Irma Hogye
Gyula Horvath
Eva Ilkoy
Attila Jakab
Antonia Jekkel
Vilmos Keri
Vera Kovacs
Ildiko Lang
Szabolcs Matyas
Imre Moravicsik
Zsuzsanna Scheidl
Csaba Szabo
Istvan Szabo
Imre Szekely
Zsuzsanna Sztaray
Original Assignee
Biogal Gyogyszergyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogal Gyogyszergyar filed Critical Biogal Gyogyszergyar
Publication of ITMI932343A0 publication Critical patent/ITMI932343A0/it
Publication of ITMI932343A1 publication Critical patent/ITMI932343A1/it
Application granted granted Critical
Publication of IT1266672B1 publication Critical patent/IT1266672B1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
IT93MI002343A 1992-11-04 1993-11-04 Procedimento per l'isolamento e la purificazione di mevinolina IT1266672B1 (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU9203458A HU210867B (en) 1992-11-04 1992-11-04 Method for extraction and purification of mevinolin from culture medium

Publications (3)

Publication Number Publication Date
ITMI932343A0 ITMI932343A0 (it) 1993-11-04
ITMI932343A1 true ITMI932343A1 (it) 1995-05-04
IT1266672B1 IT1266672B1 (it) 1997-01-09

Family

ID=10982513

Family Applications (1)

Application Number Title Priority Date Filing Date
IT93MI002343A IT1266672B1 (it) 1992-11-04 1993-11-04 Procedimento per l'isolamento e la purificazione di mevinolina

Country Status (8)

Country Link
AT (1) AT401060B (it)
CA (1) CA2127381C (it)
DE (2) DE4395515C2 (it)
ES (1) ES2081776B1 (it)
GR (1) GR930100408A (it)
HU (1) HU210867B (it)
IT (1) IT1266672B1 (it)
WO (1) WO1994010328A1 (it)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI9300303A (en) * 1993-06-08 1994-12-31 Krka Tovarna Zdravil Process for isolation of hypolipemic effective substance
UA44922C2 (uk) * 1995-12-06 2002-03-15 Балканфарма-Разград Ад Спосіб одержання ловастатину
SK282679B6 (sk) * 1999-04-16 2002-11-06 Biotika, A. S. Spôsob izolácie lovastatínu z vyfermentovanej pôdy
CZ20022779A3 (cs) * 2000-02-24 2003-02-12 Biogal Gyogyszergyar Rt. Způsob purifikace fermentačního bujónu
WO2001066538A1 (en) * 2000-03-03 2001-09-13 Biogal Gyogyszergyar Rt. A process for purifying lovastatin and simvastatin with reduced levels of dimeric impurities
ES2204285B1 (es) * 2002-05-20 2005-03-01 Ercros Industrial, S.A. Procedimiento para el aislamiento y purificacion de lovastatina.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5925599B2 (ja) * 1979-02-20 1984-06-19 三共株式会社 新生理活性物質モナコリンｋおよびその製造法
JPS55150898A (en) * 1979-05-11 1980-11-25 Sankyo Co Ltd Preparation of a new physiologically active substance mb-530b
IL60219A (en) * 1979-06-15 1985-05-31 Merck & Co Inc Hypocholesteremic fermentation products of the hmg-coa reductase inhibitor type,their preparation and pharmaceutical compositions containing them
HU208997B (en) * 1992-06-17 1994-02-28 Gyogyszerkutato Intezet Microbiological method for producing mevinoline

Also Published As

Publication number Publication date
ES2081776B1 (es) 1996-10-16
CA2127381C (en) 1997-12-23
ITMI932343A0 (it) 1993-11-04
AT401060B (de) 1996-06-25
HU210867B (en) 1995-10-30
DE4395515C2 (de) 1999-06-17
GR930100408A (el) 1994-07-29
CA2127381A1 (en) 1994-05-11
WO1994010328A1 (en) 1994-05-11
IT1266672B1 (it) 1997-01-09
DE4395515T1 (de) 1994-12-01
ATA901593A (de) 1995-10-15
ES2081776A1 (es) 1996-03-01

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19971030