ATA901593A - Verfahren zur isolierung und reinigung von mevinolin - Google Patents
Verfahren zur isolierung und reinigung von mevinolinInfo
- Publication number
- ATA901593A ATA901593A AT0901593A AT901593A ATA901593A AT A901593 A ATA901593 A AT A901593A AT 0901593 A AT0901593 A AT 0901593A AT 901593 A AT901593 A AT 901593A AT A901593 A ATA901593 A AT A901593A
- Authority
- AT
- Austria
- Prior art keywords
- mevinolin
- insulating
- cleaning
- cleaning mevinolin
- Prior art date
Links
- PCZOHLXUXFIOCF-UHFFFAOYSA-N Monacolin X Natural products C12C(OC(=O)C(C)CC)CC(C)C=C2C=CC(C)C1CCC1CC(O)CC(=O)O1 PCZOHLXUXFIOCF-UHFFFAOYSA-N 0.000 title 1
- 238000004140 cleaning Methods 0.000 title 1
- PCZOHLXUXFIOCF-BXMDZJJMSA-N lovastatin Chemical compound C([C@H]1[C@@H](C)C=CC2=C[C@H](C)C[C@@H]([C@H]12)OC(=O)[C@@H](C)CC)C[C@@H]1C[C@@H](O)CC(=O)O1 PCZOHLXUXFIOCF-BXMDZJJMSA-N 0.000 title 1
- QLJODMDSTUBWDW-UHFFFAOYSA-N lovastatin hydroxy acid Natural products C1=CC(C)C(CCC(O)CC(O)CC(O)=O)C2C(OC(=O)C(C)CC)CC(C)C=C21 QLJODMDSTUBWDW-UHFFFAOYSA-N 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/62—Carboxylic acid esters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU9203458A HU210867B (en) | 1992-11-04 | 1992-11-04 | Method for extraction and purification of mevinolin from culture medium |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA901593A true ATA901593A (de) | 1995-10-15 |
| AT401060B AT401060B (de) | 1996-06-25 |
Family
ID=10982513
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT0901593A AT401060B (de) | 1992-11-04 | 1993-09-08 | Verfahren zur isolierung und reinigung von mevinolin |
Country Status (8)
| Country | Link |
|---|---|
| AT (1) | AT401060B (de) |
| CA (1) | CA2127381C (de) |
| DE (2) | DE4395515T1 (de) |
| ES (1) | ES2081776B1 (de) |
| GR (1) | GR930100408A (de) |
| HU (1) | HU210867B (de) |
| IT (1) | IT1266672B1 (de) |
| WO (1) | WO1994010328A1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI9300303A (en) * | 1993-06-08 | 1994-12-31 | Krka Tovarna Zdravil | Process for isolation of hypolipemic effective substance |
| ES2131037T3 (es) * | 1995-12-06 | 2001-12-16 | Balkanpharma Razgrad Ad | Procedimiento de preparacion de lovastatina. |
| SK282679B6 (sk) * | 1999-04-16 | 2002-11-06 | Biotika, A. S. | Spôsob izolácie lovastatínu z vyfermentovanej pôdy |
| SK12012002A3 (sk) * | 2000-02-24 | 2003-02-04 | Biogal Gyogyszergyar Rt. | Spôsob purifikácie fermentačného bujónu |
| CZ20023201A3 (cs) * | 2000-03-03 | 2003-09-17 | Plus Chemicals S. A. | Způsob čištění lovastatinu a simvastatinu na produkt se sníženou hladinou dimerních nečistot |
| ES2204285B1 (es) * | 2002-05-20 | 2005-03-01 | Ercros Industrial, S.A. | Procedimiento para el aislamiento y purificacion de lovastatina. |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5925599B2 (ja) * | 1979-02-20 | 1984-06-19 | 三共株式会社 | 新生理活性物質モナコリンｋおよびその製造法 |
| JPS55150898A (en) * | 1979-05-11 | 1980-11-25 | Sankyo Co Ltd | Preparation of a new physiologically active substance mb-530b |
| GR69216B (de) * | 1979-06-15 | 1982-05-07 | Merck & Co Inc | |
| HU208997B (en) * | 1992-06-17 | 1994-02-28 | Gyogyszerkutato Intezet | Microbiological method for producing mevinoline |
-
1992
- 1992-11-04 HU HU9203458A patent/HU210867B/hu not_active IP Right Cessation
-
1993
- 1993-09-08 DE DE4395515T patent/DE4395515T1/de active Pending
- 1993-09-08 AT AT0901593A patent/AT401060B/de not_active IP Right Cessation
- 1993-09-08 WO PCT/HU1993/000051 patent/WO1994010328A1/en not_active IP Right Cessation
- 1993-09-08 CA CA002127381A patent/CA2127381C/en not_active Expired - Fee Related
- 1993-09-08 DE DE4395515A patent/DE4395515C2/de not_active Expired - Fee Related
- 1993-09-08 ES ES09450018A patent/ES2081776B1/es not_active Expired - Fee Related
- 1993-10-18 GR GR930100408A patent/GR930100408A/el not_active IP Right Cessation
- 1993-11-04 IT IT93MI002343A patent/IT1266672B1/it active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| AT401060B (de) | 1996-06-25 |
| WO1994010328A1 (en) | 1994-05-11 |
| ITMI932343A0 (it) | 1993-11-04 |
| GR930100408A (el) | 1994-07-29 |
| CA2127381A1 (en) | 1994-05-11 |
| ES2081776A1 (es) | 1996-03-01 |
| IT1266672B1 (it) | 1997-01-09 |
| DE4395515T1 (de) | 1994-12-01 |
| ITMI932343A1 (it) | 1995-05-04 |
| HU210867B (en) | 1995-10-30 |
| CA2127381C (en) | 1997-12-23 |
| ES2081776B1 (es) | 1996-10-16 |
| DE4395515C2 (de) | 1999-06-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ELJ | Ceased due to non-payment of the annual fee |