IT8621290A1 - 2-(aciltio)metil diidropiridine, un processo per la loro preparazione e composizioni farmaceutiche che le contengono - Google Patents

2-(aciltio)metil diidropiridine, un processo per la loro preparazione e composizioni farmaceutiche che le contengono

Info

Publication number
IT8621290A1
IT8621290A1 IT1986A21290A IT2129086A IT8621290A1 IT 8621290 A1 IT8621290 A1 IT 8621290A1 IT 1986A21290 A IT1986A21290 A IT 1986A21290A IT 2129086 A IT2129086 A IT 2129086A IT 8621290 A1 IT8621290 A1 IT 8621290A1
Authority
IT
Italy
Prior art keywords
acylthium
dihydropyridines
methyl
contain
preparation
Prior art date
Application number
IT1986A21290A
Other languages
English (en)
Other versions
IT1197012B (it
Original Assignee
Boehringer Biochemia Robin S P A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Biochemia Robin S P A filed Critical Boehringer Biochemia Robin S P A
Priority to IT21290/86A priority Critical patent/IT1197012B/it
Priority to EP87110821A priority patent/EP0255075B1/en
Priority to AT87110821T priority patent/ATE81119T1/de
Priority to DE8787110821T priority patent/DE3781973D1/de
Priority to JP62189967A priority patent/JPS6366169A/ja
Priority to US07/080,397 priority patent/US4935433A/en
Publication of IT8621290A1 publication Critical patent/IT8621290A1/it
Application granted granted Critical
Publication of IT1197012B publication Critical patent/IT1197012B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
IT21290/86A 1986-07-29 1986-07-29 2-(aciltio) metil diidropiridine, un processo per la loro preparazione e composizioni farmaceutiche che le contengono IT1197012B (it)

Priority Applications (6)

Application Number Priority Date Filing Date Title
IT21290/86A IT1197012B (it) 1986-07-29 1986-07-29 2-(aciltio) metil diidropiridine, un processo per la loro preparazione e composizioni farmaceutiche che le contengono
EP87110821A EP0255075B1 (en) 1986-07-29 1987-07-25 2-(acylthio)methyl dihydropyridines, a process for their preparation and pharmaceutical compositions containing them
AT87110821T ATE81119T1 (de) 1986-07-29 1987-07-25 2-(acylthio)methyl-dihydropyridine, ein verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.
DE8787110821T DE3781973D1 (de) 1986-07-29 1987-07-25 2-(acylthio)methyl-dihydropyridine, ein verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.
JP62189967A JPS6366169A (ja) 1986-07-29 1987-07-28 ２−（アシルチオ）メチルジヒドロピリジン、それらの製造方法及びそれらを含有する薬学的組成物
US07/080,397 US4935433A (en) 1986-07-29 1987-07-28 2-(acylthio)methyl dihydropyridines, and pharmaceutical compositions containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21290/86A IT1197012B (it) 1986-07-29 1986-07-29 2-(aciltio) metil diidropiridine, un processo per la loro preparazione e composizioni farmaceutiche che le contengono

Publications (2)

Publication Number Publication Date
IT8621290A1 true IT8621290A1 (it) 1988-01-29
IT1197012B IT1197012B (it) 1988-11-25

Family

ID=11179618

Family Applications (1)

Application Number Title Priority Date Filing Date
IT21290/86A IT1197012B (it) 1986-07-29 1986-07-29 2-(aciltio) metil diidropiridine, un processo per la loro preparazione e composizioni farmaceutiche che le contengono

Country Status (6)

Country Link
US (1) US4935433A (it)
EP (1) EP0255075B1 (it)
JP (1) JPS6366169A (it)
AT (1) ATE81119T1 (it)
DE (1) DE3781973D1 (it)
IT (1) IT1197012B (it)

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4284634A (en) * 1975-07-02 1981-08-18 Fujisawa Pharmaceutical Co., Ltd. 1,4-Dihydropyridine derivatives, and pharmaceutical method of the same
DE2658183A1 (de) * 1976-12-22 1978-07-06 Bayer Ag In 2-position substituierte 1,4- dihydropyridin-derivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
JPS57175166A (en) * 1981-04-23 1982-10-28 Banyu Pharmaceut Co Ltd Carbamoyloxyalkyl-1,4-dihydropyridine derivative and its preparation
NZ201395A (en) * 1981-07-30 1987-02-20 Bayer Ag Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines
DE3207982A1 (de) * 1982-03-05 1983-09-08 Bayer Ag, 5090 Leverkusen Neue 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihrer verwendung in arzneimitteln
IL68604A0 (en) * 1982-05-21 1983-09-30 Haessle Ab Processes for preparing therapeutically active dihydropyridines and intermediates for the processes
HU197881B (en) * 1982-08-06 1989-06-28 Banyu Pharma Co Ltd Process for producing new carbamoyl-oxy-alkyl-carboxy-lic acid derivatives
EP0107293A3 (en) * 1982-09-04 1984-06-06 Pfizer Limited Dihydropyridines
PH19166A (en) * 1982-09-04 1986-01-16 Pfizer Dihydropyridined,pharmaceutical compositions and method of use
JPS59152373A (ja) * 1983-02-16 1984-08-31 Banyu Pharmaceut Co Ltd １，４―ジヒドロピリジン誘導体
GB8306666D0 (en) * 1983-03-10 1983-04-13 Pfizer Ltd Therapeutic agents
US4568677A (en) * 1983-07-23 1986-02-04 Pfizer Inc. 2-(4-Pyrimidone alkoxyalkyl) dihydropyridine anti-ischaemic and antihypertensive agents
GB8401288D0 (en) * 1984-01-18 1984-02-22 Pfizer Ltd Therapeutic agents
DE3412947A1 (de) * 1984-04-06 1985-10-17 Bayer Ag, 5090 Leverkusen Tetrahydothienopyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
FI862343A (fi) * 1985-06-17 1986-12-18 Warner Lambert Co Foerfarande foer framstaellning av terapeutiskt verkande 1,4-dihydropyridinfoereningar.
HU199796B (en) * 1985-08-06 1990-03-28 Boehringer Biochemia Srl Process for producing 2-thiomethyl-substituted-1,4-dihydropyridines and pharmaceutical compositions comprising such compounds

Also Published As

Publication number Publication date
EP0255075B1 (en) 1992-09-30
EP0255075A1 (en) 1988-02-03
ATE81119T1 (de) 1992-10-15
DE3781973D1 (de) 1992-11-05
JPS6366169A (ja) 1988-03-24
US4935433A (en) 1990-06-19
IT1197012B (it) 1988-11-25

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