ATE89818T1 - Dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel. - Google Patents

Dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.

Info

Publication number
ATE89818T1
ATE89818T1 AT87301433T AT87301433T ATE89818T1 AT E89818 T1 ATE89818 T1 AT E89818T1 AT 87301433 T AT87301433 T AT 87301433T AT 87301433 T AT87301433 T AT 87301433T AT E89818 T1 ATE89818 T1 AT E89818T1
Authority
AT
Austria
Prior art keywords
group
alkyl
straight
formula
dihydropyridines
Prior art date
Application number
AT87301433T
Other languages
English (en)
Inventor
Claudio Semeraro
Dino Micheli
Daniele Pieraccioli
Giovanni Gaviraghi
Alan David Borthwick
Original Assignee
Glaxo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Spa filed Critical Glaxo Spa
Application granted granted Critical
Publication of ATE89818T1 publication Critical patent/ATE89818T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
AT87301433T 1986-02-20 1987-02-19 Dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel. ATE89818T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT19482/86A IT1204460B (it) 1986-02-20 1986-02-20 Derivati eterociclici
EP87301433A EP0242950B1 (de) 1986-02-20 1987-02-19 Dihydropyridine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel

Publications (1)

Publication Number Publication Date
ATE89818T1 true ATE89818T1 (de) 1993-06-15

Family

ID=11158401

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87301433T ATE89818T1 (de) 1986-02-20 1987-02-19 Dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.

Country Status (6)

Country Link
US (1) US4935548A (de)
EP (1) EP0242950B1 (de)
JP (1) JPS62252769A (de)
AT (1) ATE89818T1 (de)
DE (1) DE3785963T2 (de)
IT (1) IT1204460B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080089947A1 (en) * 2006-08-18 2008-04-17 Knox Clayton D Calcium Influx Inhibitors in the Treatment of Ischemia

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3455945A (en) * 1967-06-07 1969-07-15 Smithkline Corp 4-(carboxy (and carbo-lower alkoxy)phenyl)-1,4-dihydropyridines
DE2228363A1 (de) * 1972-06-10 1974-01-03 Bayer Ag 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
GB1591089A (en) * 1976-12-17 1981-06-10 Fujisawa Pharmaceutical Co 1,4-dihydropyridine derivatives and process for preparation thereof
US4307103A (en) * 1978-09-08 1981-12-22 Fujisawa Pharmaceutical Co., Ltd. Dihydropyridine derivative, processes for preparation thereof and pharmaceutical composition comprising the same
NZ201395A (en) * 1981-07-30 1987-02-20 Bayer Ag Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines
DE3207982A1 (de) * 1982-03-05 1983-09-08 Bayer Ag, 5090 Leverkusen Neue 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihrer verwendung in arzneimitteln
DK161312C (da) * 1982-03-11 1991-12-09 Pfizer Analogifremgangsmaade til fremstilling af 2-aminoalkoxymethyl-4-phenyl-6-methyl-1,4-dihydropyridin-3,5-dicarboxylsyreestere eller syreadditionssalte deraf samt phthalimidoderivater til anvendelse som udgangsmateriale ved fremgangsmaaden
EP0145956A1 (de) * 1983-11-16 1985-06-26 Ciba-Geigy Ag Neue Amid-Verbindungen
NZ212895A (en) * 1984-08-22 1988-07-28 Glaxo Spa 1,4-dihydropyridine derivatives and pharmaceutical compositions
IT1204462B (it) * 1986-02-20 1989-03-01 Glaxo Spa Derivati eterociclici

Also Published As

Publication number Publication date
JPS62252769A (ja) 1987-11-04
EP0242950A2 (de) 1987-10-28
DE3785963T2 (de) 1993-09-02
DE3785963D1 (de) 1993-07-01
EP0242950A3 (en) 1988-09-14
EP0242950B1 (de) 1993-05-26
US4935548A (en) 1990-06-19
IT1204460B (it) 1989-03-01
IT8619482A0 (it) 1986-02-20

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties