IT8448730A0 - Derivati di fredericamicina a aventi attivita' antibiotica ed antitumorale - Google Patents

Derivati di fredericamicina a aventi attivita' antibiotica ed antitumorale

Info

Publication number
IT8448730A0
IT8448730A0 IT8448730A IT4873084A IT8448730A0 IT 8448730 A0 IT8448730 A0 IT 8448730A0 IT 8448730 A IT8448730 A IT 8448730A IT 4873084 A IT4873084 A IT 4873084A IT 8448730 A0 IT8448730 A0 IT 8448730A0
Authority
IT
Italy
Prior art keywords
fredericamicin
antibiotic
derivatives
anticancer activity
anticancer
Prior art date
Application number
IT8448730A
Other languages
English (en)
Other versions
IT1177967B (it
IT8448730A1 (it
Inventor
Yokoi Koichi
Hasegawa Hiroshi
Nari-Ta Tadashi
Asaoka Takemitsu
Kurita Kenichi
Ishizeki Seiji
Nakashima Toshiaki
Original Assignee
Ss Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP15052283A external-priority patent/JPS6042368A/ja
Priority claimed from JP16548983A external-priority patent/JPS6056960A/ja
Priority claimed from JP16608283A external-priority patent/JPS6058964A/ja
Application filed by Ss Pharmaceutical Co filed Critical Ss Pharmaceutical Co
Publication of IT8448730A0 publication Critical patent/IT8448730A0/it
Publication of IT8448730A1 publication Critical patent/IT8448730A1/it
Application granted granted Critical
Publication of IT1177967B publication Critical patent/IT1177967B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/20—Spiro-condensed ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IT48730/84A 1983-08-18 1984-08-14 Derivati di fredericamicina a aventi attivita' antibiotica ed antitumorale IT1177967B (it)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP15052283A JPS6042368A (ja) 1983-08-18 1983-08-18 フレデリカマイシンａ−ジアシル誘導体
JP16548983A JPS6056960A (ja) 1983-09-08 1983-09-08 ロイコテトラアシルテトラハイドロフレデリカマイシンａ
JP16608283A JPS6058964A (ja) 1983-09-09 1983-09-09 新規なフレデリカマイシンａ誘導体

Publications (3)

Publication Number Publication Date
IT8448730A0 true IT8448730A0 (it) 1984-08-14
IT8448730A1 IT8448730A1 (it) 1986-02-14
IT1177967B IT1177967B (it) 1987-09-03

Family

ID=27319939

Family Applications (1)

Application Number Title Priority Date Filing Date
IT48730/84A IT1177967B (it) 1983-08-18 1984-08-14 Derivati di fredericamicina a aventi attivita' antibiotica ed antitumorale

Country Status (7)

Country Link
US (1) US4584377A (it)
CA (1) CA1267147A (it)
CH (1) CH669379A5 (it)
DE (1) DE3430365A1 (it)
FR (1) FR2550791B1 (it)
GB (1) GB2145084B (it)
IT (1) IT1177967B (it)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4673678A (en) * 1986-07-25 1987-06-16 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Water soluble derivatives of fredericamycin A
US5166208A (en) * 1991-10-09 1992-11-24 Boston College Fredericamycin A derivatives
US6462173B1 (en) * 1997-09-08 2002-10-08 Max-Planck-Gesellschaft Zur Forderung Der Inhibitors of phosphoserine and phosphothreonine-proline-specific isomerases
US6495376B1 (en) 1999-02-18 2002-12-17 Beth Israel Deaconess Medical Center Methods and compositions for regulating protein-protein interactions
US20030055072A1 (en) * 2000-12-22 2003-03-20 Lu Kun Ping Methods of inhibiting Pin1-associated states using a fredericamycin a compound
CA2480468C (en) * 2002-03-26 2012-03-13 Biofrontera Discovery Gmbh Fredericamycin derivatives
DE10248451A1 (de) * 2002-03-26 2003-10-09 Bioleads Gmbh Fredericamycin-Derivate
DE10217046A1 (de) 2002-04-17 2003-11-06 Bioleads Gmbh Fredericamycin-Derivate
WO2004002429A2 (en) * 2002-06-28 2004-01-08 Pintex Pharmaceuticals, Inc. Methods of inhibiting pin1-associated states using a fredericamycin a compound
DE10230917A1 (de) * 2002-07-09 2004-02-05 Bioleads Gmbh Fredericamycin-Derivate
US20040176277A1 (en) * 2003-03-03 2004-09-09 Pintex Pharmaceuticals, Inc. Methods of treating Pin1 associated disorders
CA2738983C (en) 2008-10-10 2018-05-15 Dana Farber Cancer Institute Chemical modulators of pro-apoptotic bax and bcl-2 polypeptides
WO2010068684A2 (en) 2008-12-09 2010-06-17 Dana Farber Cancer Institute, Inc. Methods and compositions for specific modulation of mcl-1

Also Published As

Publication number Publication date
CH669379A5 (it) 1989-03-15
US4584377A (en) 1986-04-22
GB2145084B (en) 1987-01-28
IT1177967B (it) 1987-09-03
DE3430365A1 (de) 1985-03-07
GB8420246D0 (en) 1984-09-12
IT8448730A1 (it) 1986-02-14
CA1267147A (en) 1990-03-27
FR2550791B1 (it) 1988-10-14
GB2145084A (en) 1985-03-20
FR2550791A1 (it) 1985-02-22

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