IT8322784A0 - Derivati piperazinici ad attivita'anticolinergica e/o antiistaminica. - Google Patents
Derivati piperazinici ad attivita'anticolinergica e/o antiistaminica.Info
- Publication number
- IT8322784A0 IT8322784A0 IT8322784A IT2278483A IT8322784A0 IT 8322784 A0 IT8322784 A0 IT 8322784A0 IT 8322784 A IT8322784 A IT 8322784A IT 2278483 A IT2278483 A IT 2278483A IT 8322784 A0 IT8322784 A0 IT 8322784A0
- Authority
- IT
- Italy
- Prior art keywords
- anticholinergic
- piperazine derivatives
- antihistaminic activity
- antihistaminic
- activity
- Prior art date
Links
- GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical class C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 title 1
- 230000001078 anti-cholinergic effect Effects 0.000 title 1
- 230000001387 anti-histamine Effects 0.000 title 1
- 229940066771 systemic antihistamines piperazine derivative Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/205—Radicals derived from carbonic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Anesthesiology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/424,512 US4457931A (en) | 1982-09-27 | 1982-09-27 | Piperazine derivatives with anticholinergic and/or antihistaminic activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8322784A0 true IT8322784A0 (it) | 1983-09-06 |
| IT1212088B IT1212088B (it) | 1989-11-08 |
Family
ID=23682887
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT8322784A IT1212088B (it) | 1982-09-27 | 1983-09-06 | Derivati piperazinici ad attivita'anticolinergica e/o antiistaminica. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4457931A (it) |
| JP (1) | JPS5989665A (it) |
| BE (1) | BE897828A (it) |
| DE (1) | DE3334757A1 (it) |
| ES (3) | ES8604543A1 (it) |
| FR (1) | FR2533564B1 (it) |
| GB (1) | GB2135991B (it) |
| IT (1) | IT1212088B (it) |
| NL (1) | NL8303311A (it) |
| ZA (1) | ZA836949B (it) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6147466A (ja) * | 1984-08-10 | 1986-03-07 | Dainippon Pharmaceut Co Ltd | アミン誘導体 |
| FR2573075B1 (fr) * | 1984-09-14 | 1987-03-20 | Innothera Lab Sa | Nouvelles (pyridyl-2)-1 piperazines, leur procede de preparation et leur application en therapeutique |
| JPS6314083A (ja) * | 1986-06-28 | 1988-01-21 | Nippon Denso Co Ltd | 積層型熱交換器 |
| EP0350145A3 (en) * | 1988-04-28 | 1990-07-04 | Yamanouchi Pharmaceutical Co. Ltd. | Pyridylthiazolidine carboxamide derivatives and their intermediates and production of both |
| GB2227018B (en) * | 1989-01-13 | 1992-05-20 | Wyeth John & Brother Ltd | Piperazinylalkylcarboxylic acid adamantylamides |
| JPH05255089A (ja) * | 1991-12-18 | 1993-10-05 | Sanwa Kagaku Kenkyusho Co Ltd | 抗ウイルス剤 |
| GB9817197D0 (en) * | 1998-08-07 | 1998-10-07 | Lilly Co Eli | Pharmaceutical compounds |
| DE60234453D1 (de) * | 2001-07-02 | 2009-12-31 | High Point Pharmaceuticals Llc | Substituierte piperazin- und diazepanderivate zur verwendung als histamin h3 rezeptormodulatoren |
| US20040033986A1 (en) * | 2002-05-17 | 2004-02-19 | Protopopova Marina Nikolaevna | Anti tubercular drug: compositions and methods |
| US7652039B2 (en) * | 2002-05-17 | 2010-01-26 | Sequella, Inc. | Methods of use and compositions for the diagnosis and treatment of infectious disease |
| US7456222B2 (en) * | 2002-05-17 | 2008-11-25 | Sequella, Inc. | Anti tubercular drug: compositions and methods |
| EA200600071A1 (ru) * | 2003-06-20 | 2006-08-25 | Арена Фармасьютикалз, Инк. | Производные n-фенилпиперазина и способы профилактики или лечения заболеваний, связанных с 5ht-рецептором |
| US7884097B2 (en) * | 2003-09-05 | 2011-02-08 | Sequella, Inc. | Methods and compositions comprising diamines as new anti-tubercular therapeutics |
| US20090069363A1 (en) * | 2004-12-14 | 2009-03-12 | Shionogi & Co. Ltd. A Legal Entity Of Japan | Therapeutic Agent for Constipation |
| WO2009136965A1 (en) * | 2008-05-06 | 2009-11-12 | Sequella, Inc. | Compositions and methods comprising capuramycin analogues |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR997607A (fr) * | 1949-10-14 | 1952-01-08 | American Cyanamid Co | Perfectionnements relatifs aux pipérazines substituées |
| US2794804A (en) * | 1955-03-24 | 1957-06-04 | American Cyanamid Co | Substituted piperazines and method of preparing the same |
| NL297170A (it) * | 1963-04-04 | 1900-01-01 | ||
| US3712893A (en) * | 1969-11-10 | 1973-01-23 | Cerm Cent Europ Rech Mauvernay | Butyl-piperazine derivatives |
| JPS49101383A (it) * | 1973-02-05 | 1974-09-25 | ||
| JPS517673A (ja) * | 1974-07-08 | 1976-01-22 | Hitachi Ltd | Hansoshisutemu |
| JPS5111635A (it) * | 1974-07-18 | 1976-01-29 | Hideji Kitamura | |
| FR2306694A1 (fr) * | 1975-04-07 | 1976-11-05 | Parcor | Derives de la piperazine |
| JPS523387A (en) * | 1975-06-24 | 1977-01-11 | Nec Home Electronics Ltd | Manufacturing method of semiconductor device |
| JPS54103893A (en) * | 1978-01-26 | 1979-08-15 | Morishita Pharma | 1*44benzodioxane derivative |
| AU532411B2 (en) * | 1979-03-01 | 1983-09-29 | Duphar International Research B.V. | Phenyl piperazine derivatives |
| JPS5827793B2 (ja) * | 1980-09-18 | 1983-06-11 | 住友化学工業株式会社 | 新規なアニリン誘導体の製法 |
| JPS5761149A (en) * | 1980-09-30 | 1982-04-13 | Matsushita Electric Works Ltd | Staircase |
-
1982
- 1982-09-27 US US06/424,512 patent/US4457931A/en not_active Expired - Fee Related
-
1983
- 1983-09-06 IT IT8322784A patent/IT1212088B/it active
- 1983-09-19 ZA ZA836949A patent/ZA836949B/xx unknown
- 1983-09-22 JP JP58176190A patent/JPS5989665A/ja active Granted
- 1983-09-23 FR FR8315172A patent/FR2533564B1/fr not_active Expired
- 1983-09-26 DE DE19833334757 patent/DE3334757A1/de not_active Withdrawn
- 1983-09-26 ES ES525953A patent/ES8604543A1/es not_active Expired
- 1983-09-27 GB GB08325839A patent/GB2135991B/en not_active Expired
- 1983-09-27 NL NL8303311A patent/NL8303311A/nl not_active Application Discontinuation
- 1983-09-27 BE BE2/60212A patent/BE897828A/nl not_active IP Right Cessation
-
1985
- 1985-04-16 ES ES542946A patent/ES8603442A1/es not_active Expired
- 1985-04-16 ES ES542947A patent/ES8603443A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE3334757A1 (de) | 1984-03-29 |
| ES542947A0 (es) | 1986-01-01 |
| FR2533564A1 (fr) | 1984-03-30 |
| NL8303311A (nl) | 1984-04-16 |
| JPS5989665A (ja) | 1984-05-23 |
| ZA836949B (en) | 1984-05-30 |
| US4457931A (en) | 1984-07-03 |
| GB2135991A (en) | 1984-09-12 |
| ES542946A0 (es) | 1986-01-01 |
| IT1212088B (it) | 1989-11-08 |
| ES8604543A1 (es) | 1986-02-01 |
| ES525953A0 (es) | 1986-02-01 |
| GB8325839D0 (en) | 1983-10-26 |
| GB2135991B (en) | 1985-12-04 |
| ES8603443A1 (es) | 1986-01-01 |
| BE897828A (nl) | 1984-01-16 |
| FR2533564B1 (fr) | 1986-10-03 |
| ES8603442A1 (es) | 1986-01-01 |
| JPS6139289B2 (it) | 1986-09-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE58904478D1 (de) | Strahlungsempfindliche gemische und deren verwendung. | |
| DK247789A (da) | Piperazinderivater | |
| DE3677206D1 (de) | D-luciferin-derivate und deren verwendung. | |
| DE3381562D1 (de) | Bis-kronetherderivate und ihre verwendung. | |
| DE3583593D1 (de) | Speicherhierarchie und deren betriebsverfahren. | |
| DE3871751D1 (de) | Gelbildende organosiloxanzusammensetzungen und deren verwendung. | |
| IT8419790A0 (it) | Derivati pirido-benzotiazinici ad elevata attivita' antimicrobica. | |
| IT8322784A0 (it) | Derivati piperazinici ad attivita'anticolinergica e/o antiistaminica. | |
| DK108585D0 (da) | Piperazinderivater | |
| IT8421273A0 (it) | Derivati furanici con attivita'antiulcera. | |
| DE3576341D1 (de) | Deuteroporphyrinderivate und ihre salze. | |
| IT1209856B (it) | Derivati di piperazina dotati di attivita' farmacologica | |
| DE3887417D1 (de) | Thienocinnolinverbindungen und deren verwendung als heilmittel. | |
| DE3876846D1 (de) | Morpholinderivate und deren verwendung. | |
| IT8422150A0 (it) | Composti dotati di attivita'antiallergica. | |
| IT8621194A0 (it) | Azolilderivati ad attivita'antifungina. | |
| IT1212902B (it) | Derivati etendiamminici e guanidinici dotati di attivita' farmacologica | |
| DE3876022D1 (de) | Calcitonin-derivate und deren salze. | |
| DE3889336D1 (de) | Alkyltetramethylcyclohexan-derivate und deren verwendung als duftstoffe. | |
| IT8422897A0 (it) | Derivati amminoalchilnaftalenici ad attivita' farmacologica. | |
| DK397786D0 (da) | Piperazinderivater | |
| IT1194677B (it) | Composizione farmaceutica ad attivita' antiflogistica,antipiretica e antalgica | |
| IT1113391B (it) | Derivati fenilcicloesanici ad attivita' antidepressiva | |
| IT8320237A0 (it) | Derivati tiazolidinici ad attivita' mucoregolatrice. | |
| IT8420026A0 (it) | Derivati tiazolidinici ad attivita' mucoregolatrice. |