IT8020700A0 - Processo per la preparazione di derivati di 5,11-di-idro-6h-pirido(2,3-b) (1,4)-benzodiazepin-6-one, derivati finali ed intermedi di sintesi in tal modo ottenuti. - Google Patents

Processo per la preparazione di derivati di 5,11-di-idro-6h-pirido(2,3-b) (1,4)-benzodiazepin-6-one, derivati finali ed intermedi di sintesi in tal modo ottenuti.

Info

Publication number
IT8020700A0
IT8020700A0 IT8020700A IT2070080A IT8020700A0 IT 8020700 A0 IT8020700 A0 IT 8020700A0 IT 8020700 A IT8020700 A IT 8020700A IT 2070080 A IT2070080 A IT 2070080A IT 8020700 A0 IT8020700 A0 IT 8020700A0
Authority
IT
Italy
Prior art keywords
derivatives
benzodiazepin
pyrido
hydro
preparation
Prior art date
Application number
IT8020700A
Other languages
English (en)
Other versions
IT1130973B (it
Inventor
Szepsel Gerszberg
Original Assignee
Microsules Argentina Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microsules Argentina Sa filed Critical Microsules Argentina Sa
Priority to IT20700/80A priority Critical patent/IT1130973B/it
Publication of IT8020700A0 publication Critical patent/IT8020700A0/it
Priority to FR8008809A priority patent/FR2478099A1/fr
Priority to US06/149,560 priority patent/US4308206A/en
Priority to JP7283980A priority patent/JPS56133288A/ja
Priority to ES499691A priority patent/ES8200681A1/es
Priority to AR284405A priority patent/AR226715A1/es
Priority to DE19813109769 priority patent/DE3109769A1/de
Application granted granted Critical
Publication of IT1130973B publication Critical patent/IT1130973B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
IT20700/80A 1980-03-17 1980-03-17 Processo per la preparazione di derivati di 5,11-di-idro-6h-pirido(2,3-b) (1,4)-benzodiazepin-6-one,derivati finali ed intermedi di sintesi in tal modo ottenuti IT1130973B (it)

Priority Applications (7)

Application Number Priority Date Filing Date Title
IT20700/80A IT1130973B (it) 1980-03-17 1980-03-17 Processo per la preparazione di derivati di 5,11-di-idro-6h-pirido(2,3-b) (1,4)-benzodiazepin-6-one,derivati finali ed intermedi di sintesi in tal modo ottenuti
FR8008809A FR2478099A1 (fr) 1980-03-17 1980-04-18 Procede pour la preparation de derives de 5,11-dihydro-6h-pyrido-(2,3-b)(1,4)-benzodiazepine-6-one et produits et intermediaires ainsi obtenus
US06/149,560 US4308206A (en) 1980-03-17 1980-05-13 Process for preparing derivatives of 5,11-dihydro-6h-pyrido[2,3-b][1,4]-benzodiazepin-6-one, and the final derivatives and synthesis intermediates obtained thereby
JP7283980A JPS56133288A (en) 1980-03-17 1980-06-02 5,11-dihydro-6h-pyrido(2,3-b)(1,4)- benzodiazepin-6-one derivative, synthesization intermediate and manufacture thereof
ES499691A ES8200681A1 (es) 1980-03-17 1981-02-02 Procedimiento para la preparacion de derivados de 5,11-dihi-dro-6h-pirido(2,3-b)(1,4)-benzodiazepin-6-ona
AR284405A AR226715A1 (es) 1980-03-17 1981-02-23 Procedimiento para preparar derivados de 5,11-dihidro-6h-pirido(2,3-b)(1,4)-benzodiazepin-6-ona
DE19813109769 DE3109769A1 (de) 1980-03-17 1981-03-13 Die erfindung betrifft ein neues verfahren zur herstellung von 5,11-dihydro-6h-pyrido (2,3-b) (1,4) benzodiazepin-6-on-derivaten

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT20700/80A IT1130973B (it) 1980-03-17 1980-03-17 Processo per la preparazione di derivati di 5,11-di-idro-6h-pirido(2,3-b) (1,4)-benzodiazepin-6-one,derivati finali ed intermedi di sintesi in tal modo ottenuti

Publications (2)

Publication Number Publication Date
IT8020700A0 true IT8020700A0 (it) 1980-03-17
IT1130973B IT1130973B (it) 1986-06-18

Family

ID=11170749

Family Applications (1)

Application Number Title Priority Date Filing Date
IT20700/80A IT1130973B (it) 1980-03-17 1980-03-17 Processo per la preparazione di derivati di 5,11-di-idro-6h-pirido(2,3-b) (1,4)-benzodiazepin-6-one,derivati finali ed intermedi di sintesi in tal modo ottenuti

Country Status (7)

Country Link
US (1) US4308206A (it)
JP (1) JPS56133288A (it)
AR (1) AR226715A1 (it)
DE (1) DE3109769A1 (it)
ES (1) ES8200681A1 (it)
FR (1) FR2478099A1 (it)
IT (1) IT1130973B (it)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3235795A1 (de) * 1982-09-28 1984-03-29 Dr. Karl Thomae Gmbh, 7950 Biberach Neues verfahren zur herstellung von 5,11-dihydro-11-((4-methyl-1-piperazinyl)- acetyl)- 6h-pyrido(2,3-b)(1,4)- benzodiazepin-6-on
EP0213293B1 (de) * 1985-06-27 1992-01-02 Dr. Karl Thomae GmbH In 11-Stellung substituierte 5,11-Dihydro-6H-pyrido-[2,3-b][1,4]benzodiazepin-6-one, Verfahren zur ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US5169687A (en) * 1988-09-16 1992-12-08 University Of South Florida Supercritical fluid-aided treatment of porous materials
US5324832A (en) * 1991-07-03 1994-06-28 The United States Of America As Represented By The Department Of Health And Human Services Muscarinic antagonists
FR2850654A1 (fr) * 2003-02-03 2004-08-06 Servier Lab Nouveaux derives d'azepines tricycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
KR20070033032A (ko) 2004-07-16 2007-03-23 프로테오시스 악티엔게젤샤프트 세포보호제로서 ｐａｒｐ 및 ｓｉｒ 조절 활성을 갖는무스카린 길항제
EP2387405A2 (en) 2009-01-13 2011-11-23 ProteoSys AG Pirenzepine as an agent in cancer treatment
CN106432227B (zh) * 2016-07-28 2017-12-05 常州大学 一种制备盐酸哌仑西平关键中间体的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL262921A (it) * 1960-03-30
CH438343A (de) * 1962-11-08 1967-06-30 Thomae Gmbh Dr K Verfahren zur Herstellung von 5,6-Dihydro-6-oxo-11H-pyrido (2,3-b) (1,4)-benzodiazepinen
DE1204680B (de) * 1963-05-31 1965-11-11 Thomae Gmbh Dr K Verfahren zur Herstellung von in 5-Stellung substituierten 6-Oxo-5, 6-dihydro-11H-pyrido [2, 3-b][1, 4]benzodiazepinen
FR1542160A (fr) * 1966-10-31 1968-10-11 Thomae Gmbh Dr K Procédé de fabrication de nouvelles 5, 11-dihydro-6h-pyrido-[2, 3-b] [1, 4]-benzodiazépine-6-ones substituées en position 11
FI49509C (fi) * 1968-08-20 1975-07-10 Thomae Gmbh Dr K Menetelmä farmakologisesti vaikuttavien 5-asemaan substituoitujen 5,10 -dihydro-11H-dibentso/b,e//1,4/deatsepiini-11-onien ja niiden suolojen valmistamiseksi.
DE1795183B1 (de) * 1968-08-20 1972-07-20 Thomae Gmbh Dr K 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-on-derivate und Arzneimittel
DE2724501A1 (de) * 1977-05-31 1978-12-21 Thomae Gmbh Dr K Neue, in 11-stellung substituierte 5,11-dihydro-6h-pyrido eckige klammer auf 2,3-b eckige klammer zu eckige klammer auf 1,4 eckige klammer zu benzodiazepin-6- one, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US4210648A (en) * 1977-05-31 1980-07-01 Boehringer Ingelheim Gmbh II-Aminoacyl-5,11-dihydro-6H-pyrido(2,3-B) (1,4)benzodiazepin-6-ones and salts thereof
DE2724434A1 (de) * 1977-05-31 1979-02-22 Thomae Gmbh Dr K Neue, in 11-stellung substituierte 5,11-dihydro-6h-pyrido eckige klammer auf 2,3-b eckige klammer zu eckige klammer auf 1,4 eckige klammer zu benzodiazepin-6-one, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
JPS56133288A (en) 1981-10-19
FR2478099A1 (fr) 1981-09-18
ES499691A0 (es) 1981-12-01
DE3109769A1 (de) 1981-12-24
AR226715A1 (es) 1982-08-13
IT1130973B (it) 1986-06-18
ES8200681A1 (es) 1981-12-01
US4308206A (en) 1981-12-29

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