ES499691A0 - Procedimiento para la preparacion de derivados de 5,11-dihi-dro-6h-pirido(2,3-b)(1,4)-benzodiazepin-6-ona - Google Patents
Procedimiento para la preparacion de derivados de 5,11-dihi-dro-6h-pirido(2,3-b)(1,4)-benzodiazepin-6-onaInfo
- Publication number
- ES499691A0 ES499691A0 ES499691A ES499691A ES499691A0 ES 499691 A0 ES499691 A0 ES 499691A0 ES 499691 A ES499691 A ES 499691A ES 499691 A ES499691 A ES 499691A ES 499691 A0 ES499691 A0 ES 499691A0
- Authority
- ES
- Spain
- Prior art keywords
- pirido
- dihi
- benzodiazepin
- dro
- ona
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT20700/80A IT1130973B (it) | 1980-03-17 | 1980-03-17 | Processo per la preparazione di derivati di 5,11-di-idro-6h-pirido(2,3-b) (1,4)-benzodiazepin-6-one,derivati finali ed intermedi di sintesi in tal modo ottenuti |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8200681A1 ES8200681A1 (es) | 1981-12-01 |
ES499691A0 true ES499691A0 (es) | 1981-12-01 |
Family
ID=11170749
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES499691A Granted ES499691A0 (es) | 1980-03-17 | 1981-02-02 | Procedimiento para la preparacion de derivados de 5,11-dihi-dro-6h-pirido(2,3-b)(1,4)-benzodiazepin-6-ona |
Country Status (7)
Country | Link |
---|---|
US (1) | US4308206A (es) |
JP (1) | JPS56133288A (es) |
AR (1) | AR226715A1 (es) |
DE (1) | DE3109769A1 (es) |
ES (1) | ES499691A0 (es) |
FR (1) | FR2478099A1 (es) |
IT (1) | IT1130973B (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3235795A1 (de) * | 1982-09-28 | 1984-03-29 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neues verfahren zur herstellung von 5,11-dihydro-11-((4-methyl-1-piperazinyl)- acetyl)- 6h-pyrido(2,3-b)(1,4)- benzodiazepin-6-on |
EP0213293B1 (de) * | 1985-06-27 | 1992-01-02 | Dr. Karl Thomae GmbH | In 11-Stellung substituierte 5,11-Dihydro-6H-pyrido-[2,3-b][1,4]benzodiazepin-6-one, Verfahren zur ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
US5169687A (en) * | 1988-09-16 | 1992-12-08 | University Of South Florida | Supercritical fluid-aided treatment of porous materials |
US5324832A (en) * | 1991-07-03 | 1994-06-28 | The United States Of America As Represented By The Department Of Health And Human Services | Muscarinic antagonists |
FR2850654A1 (fr) * | 2003-02-03 | 2004-08-06 | Servier Lab | Nouveaux derives d'azepines tricycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
CA2573674A1 (en) | 2004-07-16 | 2006-01-26 | Proteosys Ag | Muscarinic antagonists with parp and sir modulating activity as agents for inflammatory diseases |
EP2379080A1 (en) | 2009-01-13 | 2011-10-26 | ProteoSys AG | Pirenzepine as otoprotective agent |
CN106432227B (zh) * | 2016-07-28 | 2017-12-05 | 常州大学 | 一种制备盐酸哌仑西平关键中间体的方法 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE601886A (es) * | 1960-03-30 | |||
CH438343A (de) * | 1962-11-08 | 1967-06-30 | Thomae Gmbh Dr K | Verfahren zur Herstellung von 5,6-Dihydro-6-oxo-11H-pyrido (2,3-b) (1,4)-benzodiazepinen |
DE1204680B (de) * | 1963-05-31 | 1965-11-11 | Thomae Gmbh Dr K | Verfahren zur Herstellung von in 5-Stellung substituierten 6-Oxo-5, 6-dihydro-11H-pyrido [2, 3-b][1, 4]benzodiazepinen |
FR1542160A (fr) * | 1966-10-31 | 1968-10-11 | Thomae Gmbh Dr K | Procédé de fabrication de nouvelles 5, 11-dihydro-6h-pyrido-[2, 3-b] [1, 4]-benzodiazépine-6-ones substituées en position 11 |
FI49509C (fi) * | 1968-08-20 | 1975-07-10 | Thomae Gmbh Dr K | Menetelmä farmakologisesti vaikuttavien 5-asemaan substituoitujen 5,10 -dihydro-11H-dibentso/b,e//1,4/deatsepiini-11-onien ja niiden suolojen valmistamiseksi. |
DE1795183B1 (de) * | 1968-08-20 | 1972-07-20 | Thomae Gmbh Dr K | 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-on-derivate und Arzneimittel |
US4210648A (en) * | 1977-05-31 | 1980-07-01 | Boehringer Ingelheim Gmbh | II-Aminoacyl-5,11-dihydro-6H-pyrido(2,3-B) (1,4)benzodiazepin-6-ones and salts thereof |
DE2724501A1 (de) * | 1977-05-31 | 1978-12-21 | Thomae Gmbh Dr K | Neue, in 11-stellung substituierte 5,11-dihydro-6h-pyrido eckige klammer auf 2,3-b eckige klammer zu eckige klammer auf 1,4 eckige klammer zu benzodiazepin-6- one, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
DE2724434A1 (de) * | 1977-05-31 | 1979-02-22 | Thomae Gmbh Dr K | Neue, in 11-stellung substituierte 5,11-dihydro-6h-pyrido eckige klammer auf 2,3-b eckige klammer zu eckige klammer auf 1,4 eckige klammer zu benzodiazepin-6-one, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
-
1980
- 1980-03-17 IT IT20700/80A patent/IT1130973B/it active
- 1980-04-18 FR FR8008809A patent/FR2478099A1/fr not_active Withdrawn
- 1980-05-13 US US06/149,560 patent/US4308206A/en not_active Expired - Lifetime
- 1980-06-02 JP JP7283980A patent/JPS56133288A/ja active Pending
-
1981
- 1981-02-02 ES ES499691A patent/ES499691A0/es active Granted
- 1981-02-23 AR AR284405A patent/AR226715A1/es active
- 1981-03-13 DE DE19813109769 patent/DE3109769A1/de not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
AR226715A1 (es) | 1982-08-13 |
ES8200681A1 (es) | 1981-12-01 |
JPS56133288A (en) | 1981-10-19 |
DE3109769A1 (de) | 1981-12-24 |
FR2478099A1 (fr) | 1981-09-18 |
IT8020700A0 (it) | 1980-03-17 |
US4308206A (en) | 1981-12-29 |
IT1130973B (it) | 1986-06-18 |
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