ES499691A0 - Procedimiento para la preparacion de derivados de 5,11-dihi-dro-6h-pirido(2,3-b)(1,4)-benzodiazepin-6-ona - Google Patents

Procedimiento para la preparacion de derivados de 5,11-dihi-dro-6h-pirido(2,3-b)(1,4)-benzodiazepin-6-ona

Info

Publication number
ES499691A0
ES499691A0 ES499691A ES499691A ES499691A0 ES 499691 A0 ES499691 A0 ES 499691A0 ES 499691 A ES499691 A ES 499691A ES 499691 A ES499691 A ES 499691A ES 499691 A0 ES499691 A0 ES 499691A0
Authority
ES
Spain
Prior art keywords
pirido
dihi
benzodiazepin
dro
ona
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES499691A
Other languages
English (en)
Other versions
ES8200681A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MICROSULES ARGENTINA SA
Original Assignee
MICROSULES ARGENTINA SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MICROSULES ARGENTINA SA filed Critical MICROSULES ARGENTINA SA
Publication of ES8200681A1 publication Critical patent/ES8200681A1/es
Publication of ES499691A0 publication Critical patent/ES499691A0/es
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/75Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
ES499691A 1980-03-17 1981-02-02 Procedimiento para la preparacion de derivados de 5,11-dihi-dro-6h-pirido(2,3-b)(1,4)-benzodiazepin-6-ona Granted ES499691A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT20700/80A IT1130973B (it) 1980-03-17 1980-03-17 Processo per la preparazione di derivati di 5,11-di-idro-6h-pirido(2,3-b) (1,4)-benzodiazepin-6-one,derivati finali ed intermedi di sintesi in tal modo ottenuti

Publications (2)

Publication Number Publication Date
ES8200681A1 ES8200681A1 (es) 1981-12-01
ES499691A0 true ES499691A0 (es) 1981-12-01

Family

ID=11170749

Family Applications (1)

Application Number Title Priority Date Filing Date
ES499691A Granted ES499691A0 (es) 1980-03-17 1981-02-02 Procedimiento para la preparacion de derivados de 5,11-dihi-dro-6h-pirido(2,3-b)(1,4)-benzodiazepin-6-ona

Country Status (7)

Country Link
US (1) US4308206A (es)
JP (1) JPS56133288A (es)
AR (1) AR226715A1 (es)
DE (1) DE3109769A1 (es)
ES (1) ES499691A0 (es)
FR (1) FR2478099A1 (es)
IT (1) IT1130973B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3235795A1 (de) * 1982-09-28 1984-03-29 Dr. Karl Thomae Gmbh, 7950 Biberach Neues verfahren zur herstellung von 5,11-dihydro-11-((4-methyl-1-piperazinyl)- acetyl)- 6h-pyrido(2,3-b)(1,4)- benzodiazepin-6-on
EP0213293B1 (de) * 1985-06-27 1992-01-02 Dr. Karl Thomae GmbH In 11-Stellung substituierte 5,11-Dihydro-6H-pyrido-[2,3-b][1,4]benzodiazepin-6-one, Verfahren zur ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US5169687A (en) * 1988-09-16 1992-12-08 University Of South Florida Supercritical fluid-aided treatment of porous materials
US5324832A (en) * 1991-07-03 1994-06-28 The United States Of America As Represented By The Department Of Health And Human Services Muscarinic antagonists
FR2850654A1 (fr) * 2003-02-03 2004-08-06 Servier Lab Nouveaux derives d'azepines tricycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CA2573674A1 (en) 2004-07-16 2006-01-26 Proteosys Ag Muscarinic antagonists with parp and sir modulating activity as agents for inflammatory diseases
EP2379080A1 (en) 2009-01-13 2011-10-26 ProteoSys AG Pirenzepine as otoprotective agent
CN106432227B (zh) * 2016-07-28 2017-12-05 常州大学 一种制备盐酸哌仑西平关键中间体的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE601886A (es) * 1960-03-30
CH438343A (de) * 1962-11-08 1967-06-30 Thomae Gmbh Dr K Verfahren zur Herstellung von 5,6-Dihydro-6-oxo-11H-pyrido (2,3-b) (1,4)-benzodiazepinen
DE1204680B (de) * 1963-05-31 1965-11-11 Thomae Gmbh Dr K Verfahren zur Herstellung von in 5-Stellung substituierten 6-Oxo-5, 6-dihydro-11H-pyrido [2, 3-b][1, 4]benzodiazepinen
FR1542160A (fr) * 1966-10-31 1968-10-11 Thomae Gmbh Dr K Procédé de fabrication de nouvelles 5, 11-dihydro-6h-pyrido-[2, 3-b] [1, 4]-benzodiazépine-6-ones substituées en position 11
FI49509C (fi) * 1968-08-20 1975-07-10 Thomae Gmbh Dr K Menetelmä farmakologisesti vaikuttavien 5-asemaan substituoitujen 5,10 -dihydro-11H-dibentso/b,e//1,4/deatsepiini-11-onien ja niiden suolojen valmistamiseksi.
DE1795183B1 (de) * 1968-08-20 1972-07-20 Thomae Gmbh Dr K 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-on-derivate und Arzneimittel
US4210648A (en) * 1977-05-31 1980-07-01 Boehringer Ingelheim Gmbh II-Aminoacyl-5,11-dihydro-6H-pyrido(2,3-B) (1,4)benzodiazepin-6-ones and salts thereof
DE2724501A1 (de) * 1977-05-31 1978-12-21 Thomae Gmbh Dr K Neue, in 11-stellung substituierte 5,11-dihydro-6h-pyrido eckige klammer auf 2,3-b eckige klammer zu eckige klammer auf 1,4 eckige klammer zu benzodiazepin-6- one, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE2724434A1 (de) * 1977-05-31 1979-02-22 Thomae Gmbh Dr K Neue, in 11-stellung substituierte 5,11-dihydro-6h-pyrido eckige klammer auf 2,3-b eckige klammer zu eckige klammer auf 1,4 eckige klammer zu benzodiazepin-6-one, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
AR226715A1 (es) 1982-08-13
ES8200681A1 (es) 1981-12-01
JPS56133288A (en) 1981-10-19
DE3109769A1 (de) 1981-12-24
FR2478099A1 (fr) 1981-09-18
IT8020700A0 (it) 1980-03-17
US4308206A (en) 1981-12-29
IT1130973B (it) 1986-06-18

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