IT7920138A0 - Analoghi della prostaciclina. - Google Patents
Analoghi della prostaciclina.Info
- Publication number
- IT7920138A0 IT7920138A0 IT7920138A IT2013879A IT7920138A0 IT 7920138 A0 IT7920138 A0 IT 7920138A0 IT 7920138 A IT7920138 A IT 7920138A IT 2013879 A IT2013879 A IT 2013879A IT 7920138 A0 IT7920138 A0 IT 7920138A0
- Authority
- IT
- Italy
- Prior art keywords
- prostacyclin analogues
- prostacyclin
- analogues
- Prior art date
Links
- KAQKFAOMNZTLHT-VVUHWYTRSA-N epoprostenol Chemical class O1C(=CCCCC(O)=O)C[C@@H]2[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C[C@@H]21 KAQKFAOMNZTLHT-VVUHWYTRSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/09—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis
- C07C29/095—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis of esters of organic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/005—Analogues or derivatives having the five membered ring replaced by other rings
- C07C405/0075—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system
- C07C405/0083—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system which is only ortho or peri condensed, e.g. carbacyclins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
- C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
- C07C45/60—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in six-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/62—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by hydrogenation of carbon-to-carbon double or triple bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/64—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of functional groups containing oxygen only in singly bound form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
- C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/08—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing three- or four-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/877,253 US4705806A (en) | 1978-02-13 | 1978-02-13 | Prostacyclin analogs |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT7920138A0 true IT7920138A0 (it) | 1979-02-12 |
| IT1113024B IT1113024B (it) | 1986-01-20 |
Family
ID=25369560
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT20138/79A IT1113024B (it) | 1978-02-13 | 1979-02-12 | Analoghi della prostaciclina |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4705806A (it) |
| JP (1) | JPS5823869B2 (it) |
| AU (1) | AU536416B2 (it) |
| BE (1) | BE874135A (it) |
| CH (2) | CH639062A5 (it) |
| DE (1) | DE2904655A1 (it) |
| FR (1) | FR2424908A1 (it) |
| GB (1) | GB2014143B (it) |
| IE (1) | IE48178B1 (it) |
| IL (2) | IL56479A0 (it) |
| IT (1) | IT1113024B (it) |
| NL (2) | NL7901070A (it) |
| SE (1) | SE7901126L (it) |
| ZA (1) | ZA79176B (it) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2038333B (en) * | 1978-01-26 | 1982-10-06 | Erba Farmitalia | 12 -formyl- (20 12)octanor-9-deoxy-9 -methylene pgi derivatives |
| US4525586A (en) * | 1980-02-28 | 1985-06-25 | The Upjohn Company | Composition and process |
| DE3048906A1 (de) * | 1980-12-19 | 1982-07-15 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| DE3104044A1 (de) * | 1981-02-02 | 1982-08-26 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue prostacyclin-derivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| DE3121155A1 (de) * | 1981-05-22 | 1982-12-09 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| DE3221193A1 (de) * | 1982-05-28 | 1983-12-01 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue carbacyclinester, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| DE3225287A1 (de) * | 1982-07-02 | 1984-01-05 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue carbacyclinamide, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| DE3226550A1 (de) * | 1982-07-13 | 1984-01-19 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| JPS5951276A (ja) * | 1982-09-17 | 1984-03-24 | Ono Pharmaceut Co Ltd | ビシクロ〔３．３．０〕オクタン誘導体及びその製造方法 |
| GB2156340A (en) * | 1984-03-26 | 1985-10-09 | Erba Farmitalia | 1-Nor-2-hydroxymethyl-derivatives of carboprostacyclins and process for their preparation |
| JPS6188975U (it) * | 1984-11-16 | 1986-06-10 | ||
| US4678805A (en) * | 1985-03-27 | 1987-07-07 | Syntex (U.S.A.) Inc. | Novel 8-(lower alkyl)bicyclo[4.2.0]octane derivatives with valuable therapeutic properties |
| US4608388A (en) * | 1985-03-27 | 1986-08-26 | Syntex (U.S.A.) Inc. | Novel [4,2,0]bicyclooctane derivatives with valuable therapeutic properties |
| JPH0313502Y2 (it) * | 1985-06-28 | 1991-03-27 | ||
| JPH0313492Y2 (it) * | 1985-07-22 | 1991-03-27 | ||
| DE3777640D1 (it) * | 1986-11-28 | 1992-04-23 | The Liposome Co.,Inc., Princeton, N.J., Us | |
| AU669783B2 (en) * | 1993-02-03 | 1996-06-20 | Teijin Limited | Dermatologic preparation composition containing prostacyclinas active ingredient |
| ATE306256T1 (de) * | 1999-08-05 | 2005-10-15 | Teijin Ltd | Mittel zur besserung der neuropathie, die als wirkstoff stickstoffhaltige verbindungen enthalten |
| BRPI0918134B1 (pt) * | 2008-09-10 | 2019-02-12 | Kaken Pharmaceutical Co., Ltd | Derivado de prostaglandina i2 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1060007A (en) * | 1975-02-18 | 1979-08-07 | Gilbert A. Youngdale | 2a,2b-dihomo-16,16-dimethyl-prostaglandin analogs |
| IL51189A (en) * | 1976-02-04 | 1985-08-30 | Upjohn Co | Prostaglandin analogs |
-
1978
- 1978-02-13 US US05/877,253 patent/US4705806A/en not_active Expired - Lifetime
-
1979
- 1979-01-16 ZA ZA00790176A patent/ZA79176B/xx unknown
- 1979-01-23 IL IL56479A patent/IL56479A0/xx unknown
- 1979-01-24 AU AU43605/79A patent/AU536416B2/en not_active Ceased
- 1979-02-06 GB GB7904068A patent/GB2014143B/en not_active Expired
- 1979-02-07 DE DE19792904655 patent/DE2904655A1/de not_active Ceased
- 1979-02-08 SE SE7901126A patent/SE7901126L/xx not_active Application Discontinuation
- 1979-02-12 FR FR7903536A patent/FR2424908A1/fr active Granted
- 1979-02-12 NL NL7901070A patent/NL7901070A/xx not_active Application Discontinuation
- 1979-02-12 CH CH136079A patent/CH639062A5/de not_active IP Right Cessation
- 1979-02-12 IT IT20138/79A patent/IT1113024B/it active
- 1979-02-12 IE IE270/79A patent/IE48178B1/en unknown
- 1979-02-13 BE BE0/193434A patent/BE874135A/xx not_active IP Right Cessation
- 1979-02-13 JP JP54014413A patent/JPS5823869B2/ja not_active Expired
-
1980
- 1980-06-20 NL NL8003579A patent/NL8003579A/nl not_active Application Discontinuation
- 1980-07-04 IL IL60491A patent/IL60491A0/xx unknown
- 1980-11-11 CH CH836480A patent/CH638483A5/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IE48178B1 (en) | 1984-10-17 |
| FR2424908B1 (it) | 1982-04-16 |
| BE874135A (fr) | 1979-08-13 |
| CH638483A5 (de) | 1983-09-30 |
| GB2014143A (en) | 1979-08-22 |
| NL7901070A (nl) | 1979-08-15 |
| FR2424908A1 (fr) | 1979-11-30 |
| IL56479A0 (en) | 1979-03-12 |
| IT1113024B (it) | 1986-01-20 |
| DE2904655A1 (de) | 1979-08-23 |
| JPS54117450A (en) | 1979-09-12 |
| GB2014143B (en) | 1982-08-04 |
| IL60491A0 (en) | 1980-09-16 |
| ZA79176B (en) | 1979-12-27 |
| AU4360579A (en) | 1979-08-23 |
| JPS5823869B2 (ja) | 1983-05-18 |
| IE790270L (en) | 1979-08-13 |
| CH639062A5 (de) | 1983-10-31 |
| US4705806A (en) | 1987-11-10 |
| SE7901126L (sv) | 1979-08-14 |
| AU536416B2 (en) | 1984-05-10 |
| NL8003579A (nl) | 1980-09-30 |
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