IT7823151A0 - Nuove antracicline antitumorali sostituite. - Google Patents

Nuove antracicline antitumorali sostituite.

Info

Publication number
IT7823151A0
IT7823151A0 IT7823151A IT2315178A IT7823151A0 IT 7823151 A0 IT7823151 A0 IT 7823151A0 IT 7823151 A IT7823151 A IT 7823151A IT 2315178 A IT2315178 A IT 2315178A IT 7823151 A0 IT7823151 A0 IT 7823151A0
Authority
IT
Italy
Prior art keywords
anthraciclines
anticancer
new replaced
replaced
new
Prior art date
Application number
IT7823151A
Other languages
English (en)
Other versions
IT1098212B (it
Inventor
Penco Sergio
Gozzi Fausto
Angelucci Francesco
Arcamone Federico
Original Assignee
Farmaceutici Italia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmaceutici Italia filed Critical Farmaceutici Italia
Publication of IT7823151A0 publication Critical patent/IT7823151A0/it
Priority to IT23151/78A priority Critical patent/IT1098212B/it
Priority to US05/941,847 priority patent/US4199571A/en
Priority to US06/033,995 priority patent/US4229355A/en
Priority to US06/033,994 priority patent/US4216157A/en
Priority to YU01052/79A priority patent/YU105279A/xx
Priority to GB7915553A priority patent/GB2021571B/en
Priority to NL7903539A priority patent/NL7903539A/xx
Priority to HU79SO1249A priority patent/HU180298B/hu
Priority to AU46684/79A priority patent/AU528439B2/en
Priority to IL57219A priority patent/IL57219A/xx
Priority to CS793162A priority patent/CS207789B2/cs
Priority to ZA792177A priority patent/ZA792177B/xx
Priority to FR7911445A priority patent/FR2425446A1/fr
Priority to NO791520A priority patent/NO147310C/no
Priority to DK188079A priority patent/DK188079A/da
Priority to AT0340879A priority patent/AT363186B/de
Priority to JP5684179A priority patent/JPS5513264A/ja
Priority to CH427079A priority patent/CH640869A5/de
Priority to DE19792918291 priority patent/DE2918291A1/de
Priority to SE7903972A priority patent/SE7903972L/xx
Priority to CA327,216A priority patent/CA1128503A/en
Priority to BE0/195034A priority patent/BE876099A/xx
Priority to SU792763508A priority patent/SU867315A3/ru
Priority to IE906/79A priority patent/IE48371B1/en
Application granted granted Critical
Publication of IT1098212B publication Critical patent/IT1098212B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/32—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by aldehydo- or ketonic radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/08—1,3-Dioxanes; Hydrogenated 1,3-dioxanes condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
IT23151/78A 1978-05-09 1978-05-09 Antracioline antitumorali sostituite IT1098212B (it)

Priority Applications (24)

Application Number Priority Date Filing Date Title
IT23151/78A IT1098212B (it) 1978-05-09 1978-05-09 Antracioline antitumorali sostituite
US05/941,847 US4199571A (en) 1978-05-09 1978-09-13 Substituted anthracyclines, their preparation and use
US06/033,995 US4229355A (en) 1978-05-09 1979-04-27 9-Deoxy-9,10-epoxide-daunomycinone
US06/033,994 US4216157A (en) 1978-05-09 1979-04-27 Substituted antitumor anthracyclines
YU01052/79A YU105279A (en) 1978-05-09 1979-05-04 Process for obtaining new glucoside
GB7915553A GB2021571B (en) 1978-05-09 1979-05-04 Anthracycline glycosides
NL7903539A NL7903539A (nl) 1978-05-09 1979-05-04 Nieuwe gesubstitueerde antitumor-antracyclinen en hun bereiding.
HU79SO1249A HU180298B (en) 1978-05-09 1979-05-04 Process for preparing new glycoside compunds
AU46684/79A AU528439B2 (en) 1978-05-09 1979-05-04 Anthracycline glycosides
IL57219A IL57219A (en) 1978-05-09 1979-05-06 10-methoxy-daunorubicin,10-methoxy-doxorubicin,their derivatives,preparation thereof,and pharmaceutical compositions comprising them
CS793162A CS207789B2 (en) 1978-05-09 1979-05-06 Method of making the new glycosides
DE19792918291 DE2918291A1 (de) 1978-05-09 1979-05-07 Neue substituierte antitumoranthracycline und verfahren zu deren herstellung
ZA792177A ZA792177B (en) 1978-05-09 1979-05-07 Anthracycline glycosides
NO791520A NO147310C (no) 1978-05-09 1979-05-07 Fremgangsmaate for fremstilling av substituerte antitumorantracykliner
DK188079A DK188079A (da) 1978-05-09 1979-05-07 Fremgangsmaade til fremstilling af antitumoraktive substituere anthracycliner
AT0340879A AT363186B (de) 1978-05-09 1979-05-07 Verfahren zur herstellung von glycosiden
JP5684179A JPS5513264A (en) 1978-05-09 1979-05-07 Novel substituted anthracycline
CH427079A CH640869A5 (de) 1978-05-09 1979-05-07 Substituierte antitumoranthracycline und verfahren zu deren herstellung.
FR7911445A FR2425446A1 (fr) 1978-05-09 1979-05-07 Nouvelles anthracyclines substituees utilisables comme medicament antitumoral
SE7903972A SE7903972L (sv) 1978-05-09 1979-05-07 Substituerade antitumorantracykliner och forfarande for deras framstellning
CA327,216A CA1128503A (en) 1978-05-09 1979-05-08 Process for the preparation of substituted antitumor anthracyclines
BE0/195034A BE876099A (fr) 1978-05-09 1979-05-08 Nouvelles anthracyclines substituees utilisables comme medicament antitumoral
SU792763508A SU867315A3 (ru) 1978-05-09 1979-05-08 Способ получени хлоргидратов замещенных антрациклинов
IE906/79A IE48371B1 (en) 1978-05-09 1979-08-08 Anthracycline glycosides

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT23151/78A IT1098212B (it) 1978-05-09 1978-05-09 Antracioline antitumorali sostituite

Publications (2)

Publication Number Publication Date
IT7823151A0 true IT7823151A0 (it) 1978-05-09
IT1098212B IT1098212B (it) 1985-09-07

Family

ID=11204317

Family Applications (1)

Application Number Title Priority Date Filing Date
IT23151/78A IT1098212B (it) 1978-05-09 1978-05-09 Antracioline antitumorali sostituite

Country Status (22)

Country Link
US (3) US4199571A (it)
JP (1) JPS5513264A (it)
AT (1) AT363186B (it)
AU (1) AU528439B2 (it)
BE (1) BE876099A (it)
CA (1) CA1128503A (it)
CH (1) CH640869A5 (it)
CS (1) CS207789B2 (it)
DE (1) DE2918291A1 (it)
DK (1) DK188079A (it)
FR (1) FR2425446A1 (it)
GB (1) GB2021571B (it)
HU (1) HU180298B (it)
IE (1) IE48371B1 (it)
IL (1) IL57219A (it)
IT (1) IT1098212B (it)
NL (1) NL7903539A (it)
NO (1) NO147310C (it)
SE (1) SE7903972L (it)
SU (1) SU867315A3 (it)
YU (1) YU105279A (it)
ZA (1) ZA792177B (it)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1210476B (it) * 1981-05-28 1989-09-14 Erba Farmitalia Antracicline.
US4563444A (en) * 1982-05-26 1986-01-07 Farmitalia Carlo Erba S.P.A. Anthracycline glycosides, use and compositions containing same
IT1155446B (it) * 1982-12-23 1987-01-28 Erba Farmitalia Procedimento per la purificazione di glucosidi antraciclinonici mediante adsobimento selettivo su resine
US4489206A (en) * 1983-05-13 1984-12-18 Adria Laboratories, Inc. Synthesis of (+)-4-demethoxydaunomycinone
JPH0528280Y2 (it) * 1986-12-10 1993-07-20
WO2004087097A2 (en) * 2003-03-31 2004-10-14 Yissum Research Development Company Of The Hebrew University Of Jerusalem Stable liposomes or micelles comprising a sphinolipid and a peg-lipopolymer
CA2587470A1 (en) * 2004-11-15 2006-05-18 Yissum Research Development Company Of The Hebrew University Of Jerusale M Combination therapy associating preferably a ceramide with a cytotoxic drug

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3201424A (en) * 1962-10-29 1965-08-17 American Cyanamid Co Derivatives of 1, 3, 11, 12-tetrahydroxynaphthacene and 1, 3, 6, 11-tetrahydroxynaphtacene-5, 12-quinone
US3803124A (en) * 1968-04-12 1974-04-09 Farmaceutici It Soc Process for the preparation of adriamycin and adriamycinone and adriamycin derivatives
US3686163A (en) * 1968-05-14 1972-08-22 Farmaceutici Italia Dihydrodaunomycin antibiotic and derivatives thereof
FI51808C (fi) * 1968-07-15 1977-04-12 Rhone Poulenc Sa Menetelmä uusien kasvainten naftaseenijohdannaisten valmistamiseksi.
US4020270A (en) * 1974-05-02 1977-04-26 Societa' Farmaceutici Italia S.P.A. L-lyxohex-1-enopyranose derivative
GB1461190A (en) * 1974-09-20 1977-01-13 Farmaceutici Italia Anthracycline preparation
US4133877A (en) * 1976-07-08 1979-01-09 Societa Farmaceutici Italia S.P.A. Anthracycline ethers and use therefor
GB1561719A (en) * 1976-12-22 1980-02-27 Farmaceutici Italia Anthracyclines

Also Published As

Publication number Publication date
JPS5513264A (en) 1980-01-30
IE48371B1 (en) 1984-12-26
CH640869A5 (de) 1984-01-31
ATA340879A (de) 1980-12-15
IE790906L (en) 1979-11-09
AU4668479A (en) 1979-11-15
US4216157A (en) 1980-08-05
FR2425446A1 (fr) 1979-12-07
SE7903972L (sv) 1979-11-10
NL7903539A (nl) 1979-11-13
DK188079A (da) 1979-11-10
CS207789B2 (en) 1981-08-31
NO147310C (no) 1983-03-16
NO147310B (no) 1982-12-06
IT1098212B (it) 1985-09-07
CA1128503A (en) 1982-07-27
IL57219A (en) 1982-12-31
GB2021571B (en) 1982-09-29
HU180298B (en) 1983-02-28
US4229355A (en) 1980-10-21
AU528439B2 (en) 1983-04-28
YU105279A (en) 1982-10-31
SU867315A3 (ru) 1981-09-23
US4199571A (en) 1980-04-22
FR2425446B1 (it) 1982-07-30
ZA792177B (en) 1980-05-28
AT363186B (de) 1981-07-10
IL57219A0 (en) 1979-09-30
NO791520L (no) 1979-11-12
BE876099A (fr) 1979-11-08
DE2918291A1 (de) 1979-11-15
GB2021571A (en) 1979-12-05

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