IT1254883B - Tetrapeptidi parzialmente modificati e retroinvertiti, analoghi di frammenti della proteina c-reattiva. - Google Patents

Tetrapeptidi parzialmente modificati e retroinvertiti, analoghi di frammenti della proteina c-reattiva.

Info

Publication number
IT1254883B
IT1254883B ITMI920939A ITMI920939A IT1254883B IT 1254883 B IT1254883 B IT 1254883B IT MI920939 A ITMI920939 A IT MI920939A IT MI920939 A ITMI920939 A IT MI920939A IT 1254883 B IT1254883 B IT 1254883B
Authority
IT
Italy
Prior art keywords
pct
chain
tetrapeptides
retroinverted
analogs
Prior art date
Application number
ITMI920939A
Other languages
English (en)
Inventor
Antonio Silvio Verdini
Massimo Pinori
Silvana Cappelletti
Laura Gazerro
Flavio Leoni
Original Assignee
Italfarmaco Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Italfarmaco Spa filed Critical Italfarmaco Spa
Publication of ITMI920939A0 publication Critical patent/ITMI920939A0/it
Priority to ITMI920939A priority Critical patent/IT1254883B/it
Priority to AU39514/93A priority patent/AU667096B2/en
Priority to NZ251697A priority patent/NZ251697A/en
Priority to US08/307,580 priority patent/US5521159A/en
Priority to EP93908898A priority patent/EP0636140B1/en
Priority to JP05517942A priority patent/JP3036844B2/ja
Priority to AT93908898T priority patent/ATE157987T1/de
Priority to HU9402952A priority patent/HUT70179A/hu
Priority to CA002118136A priority patent/CA2118136C/en
Priority to KR1019940703644A priority patent/KR100255526B1/ko
Priority to DE69313842T priority patent/DE69313842T2/de
Priority to PCT/EP1993/000825 priority patent/WO1993021208A1/en
Priority to ES93908898T priority patent/ES2109487T3/es
Priority to ZA932614A priority patent/ZA932614B/xx
Priority to TW082102851A priority patent/TW242145B/zh
Priority to CN93104449A priority patent/CN1039124C/zh
Publication of ITMI920939A1 publication Critical patent/ITMI920939A1/it
Priority to FI944224A priority patent/FI944224A0/fi
Priority to NO943903A priority patent/NO943903L/no
Application granted granted Critical
Publication of IT1254883B publication Critical patent/IT1254883B/it
Priority to US08/608,317 priority patent/US5578575A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0212—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -N-C-N-C(=0)-, e.g. retro-inverso peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
ITMI920939A 1992-04-16 1992-04-16 Tetrapeptidi parzialmente modificati e retroinvertiti, analoghi di frammenti della proteina c-reattiva. IT1254883B (it)

Priority Applications (19)

Application Number Priority Date Filing Date Title
ITMI920939A IT1254883B (it) 1992-04-16 1992-04-16 Tetrapeptidi parzialmente modificati e retroinvertiti, analoghi di frammenti della proteina c-reattiva.
DE69313842T DE69313842T2 (de) 1992-04-16 1993-04-02 Teilweise modifizierte und retro-invertierte tetrapeptides analogue von fragmenten des c reaktiven proteins
ES93908898T ES2109487T3 (es) 1992-04-16 1993-04-02 Analogos de tetrapeptidos parcialmente modificados y retroinvertidos de fragmentos de proteina c-reactiva.
US08/307,580 US5521159A (en) 1992-04-16 1993-04-02 Partially modified and retro-inverted tetrapeptides analogues of C-reactive protein fragments
EP93908898A EP0636140B1 (en) 1992-04-16 1993-04-02 Partially modified and retro-inverted tetrapeptides analogues of c-reactive protein fragments
JP05517942A JP3036844B2 (ja) 1992-04-16 1993-04-02 Ｃ反応性タンパク断片の部分修飾及び逆転置テトラペプチド類似体
AT93908898T ATE157987T1 (de) 1992-04-16 1993-04-02 Teilweise modifizierte und retro-invertierte tetrapeptides analogue von fragmenten des c reaktiven proteins
HU9402952A HUT70179A (en) 1992-04-16 1993-04-02 Process for producing retroinverted tetrapeptides and pharmaceutical compositions containing them as active component
CA002118136A CA2118136C (en) 1992-04-16 1993-04-02 Partially modified and retro-inverted tetrapeptides analogues of c-reactive protein fragments
KR1019940703644A KR100255526B1 (ko) 1992-04-16 1993-04-02 C-반응성 단백질 단편의 부분적으로 변형되고 역-전화된 테트라펩티드 유사체
AU39514/93A AU667096B2 (en) 1992-04-16 1993-04-02 Partially modified and retro-inverted tetrapeptides analogues of C-reactive protein fragments
PCT/EP1993/000825 WO1993021208A1 (en) 1992-04-16 1993-04-02 Partially modified and retro-inverted tetrapeptides analogues of c-reactive protein fragments
NZ251697A NZ251697A (en) 1992-04-16 1993-04-02 Tetrapeptides which are analogues of c-reactive protein fragments; pharmaceutical compositions thereof
ZA932614A ZA932614B (en) 1992-04-16 1993-04-14 Partially modified and retro-inverted tetrapeptides analogues of C-reactive protein fragments
TW082102851A TW242145B (it) 1992-04-16 1993-04-14
CN93104449A CN1039124C (zh) 1992-04-16 1993-04-14 C-反应性蛋白质片段的部分改性的和逆转化的四肽类似物及药物组合物
FI944224A FI944224A0 (fi) 1992-04-16 1994-09-13 C-reaktiivisten proteiinifragmenttien osittain modifioidut ja retroinvertoidut tetrapeptidianalogit
NO943903A NO943903L (no) 1992-04-16 1994-10-14 Partielt modifiserte og retroinverterte tetrapeptidanaloger av fragmenter av C-reaktivt protein
US08/608,317 US5578575A (en) 1992-04-16 1996-02-28 Partially modified and retro-inverted tetrapeptides analogues of C-reactive protein fragments

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI920939A IT1254883B (it) 1992-04-16 1992-04-16 Tetrapeptidi parzialmente modificati e retroinvertiti, analoghi di frammenti della proteina c-reattiva.

Publications (3)

Publication Number Publication Date
ITMI920939A0 ITMI920939A0 (it) 1992-04-16
ITMI920939A1 ITMI920939A1 (it) 1993-10-16
IT1254883B true IT1254883B (it) 1995-10-11

Family

ID=11362983

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI920939A IT1254883B (it) 1992-04-16 1992-04-16 Tetrapeptidi parzialmente modificati e retroinvertiti, analoghi di frammenti della proteina c-reattiva.

Country Status (18)

Country Link
US (2) US5521159A (it)
EP (1) EP0636140B1 (it)
JP (1) JP3036844B2 (it)
KR (1) KR100255526B1 (it)
CN (1) CN1039124C (it)
AT (1) ATE157987T1 (it)
AU (1) AU667096B2 (it)
CA (1) CA2118136C (it)
DE (1) DE69313842T2 (it)
ES (1) ES2109487T3 (it)
FI (1) FI944224A0 (it)
HU (1) HUT70179A (it)
IT (1) IT1254883B (it)
NO (1) NO943903L (it)
NZ (1) NZ251697A (it)
TW (1) TW242145B (it)
WO (1) WO1993021208A1 (it)
ZA (1) ZA932614B (it)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1254883B (it) * 1992-04-16 1995-10-11 Italfarmaco Spa Tetrapeptidi parzialmente modificati e retroinvertiti, analoghi di frammenti della proteina c-reattiva.
IT1271486B (it) * 1993-10-12 1997-05-28 Italfarmaco Spa Oligopeptidi immunomodulatori derivati di frammenti della proteina c- reattiva
BR9916732A (pt) * 1999-01-02 2001-09-25 Aventis Pharma Gmbh Derivados de ácido malÈnico, processo para a sua preparação, seu uso e composições farmacêuticas contendo-os (inibição da atividade do fator xa)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0253190B1 (en) * 1986-07-16 1992-12-30 ENIRICERCHE S.p.A. Partially retro-inverted tuftsin analogues, method for the preparation thereof and pharmaceutical compositions containing them
IT1254883B (it) * 1992-04-16 1995-10-11 Italfarmaco Spa Tetrapeptidi parzialmente modificati e retroinvertiti, analoghi di frammenti della proteina c-reattiva.

Also Published As

Publication number Publication date
FI944224A (fi) 1994-09-13
TW242145B (it) 1995-03-01
HUT70179A (en) 1995-09-28
JP3036844B2 (ja) 2000-04-24
AU3951493A (en) 1993-11-18
HU9402952D0 (en) 1995-02-28
NZ251697A (en) 1995-10-26
DE69313842D1 (de) 1997-10-16
EP0636140B1 (en) 1997-09-10
ES2109487T3 (es) 1998-01-16
ITMI920939A1 (it) 1993-10-16
AU667096B2 (en) 1996-03-07
CA2118136C (en) 2002-03-26
US5578575A (en) 1996-11-26
ATE157987T1 (de) 1997-09-15
WO1993021208A1 (en) 1993-10-28
CN1039124C (zh) 1998-07-15
EP0636140A1 (en) 1995-02-01
JPH07505640A (ja) 1995-06-22
NO943903L (no) 1994-12-15
CA2118136A1 (en) 1993-10-28
US5521159A (en) 1996-05-28
CN1078476A (zh) 1993-11-17
DE69313842T2 (de) 1998-04-09
KR100255526B1 (ko) 2000-05-01
ITMI920939A0 (it) 1992-04-16
FI944224A0 (fi) 1994-09-13
ZA932614B (en) 1993-10-26
NO943903D0 (no) 1994-10-14

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970428