IT1254708B - Procedimento a cuprato organico per preparare cefprozil - Google Patents

Procedimento a cuprato organico per preparare cefprozil

Info

Publication number
IT1254708B
IT1254708B ITMI910610A ITMI910610A IT1254708B IT 1254708 B IT1254708 B IT 1254708B IT MI910610 A ITMI910610 A IT MI910610A IT MI910610 A ITMI910610 A IT MI910610A IT 1254708 B IT1254708 B IT 1254708B
Authority
IT
Italy
Prior art keywords
procedure
cefprozil
preparing
organic cuprate
organic
Prior art date
Application number
ITMI910610A
Other languages
English (en)
Inventor
Kant Joydeep
Sapino Chester Jr
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of ITMI910610A0 publication Critical patent/ITMI910610A0/it
Publication of ITMI910610A1 publication Critical patent/ITMI910610A1/it
Application granted granted Critical
Publication of IT1254708B publication Critical patent/IT1254708B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

Intermedi di cefalosporina aventi un gruppo sostituibile di organosolfonilossi o sterociclotio nella posizione 3 sono assoggettati ad un processo di alchilazione con carboni con reagenti organici di rame per ottenere antibiotici di cefalosporina sostituiti in posizione 3 con idrocarburo.
ITMI910610A 1990-03-08 1991-03-08 Procedimento a cuprato organico per preparare cefprozil IT1254708B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/490,213 US5043439A (en) 1990-03-08 1990-03-08 Process for production of cephalosporins
CS91916A CZ282689B6 (cs) 1990-03-08 1991-04-03 Způsob výroby cefalosporinových antibiotik

Publications (3)

Publication Number Publication Date
ITMI910610A0 ITMI910610A0 (it) 1991-03-08
ITMI910610A1 ITMI910610A1 (it) 1992-09-08
IT1254708B true IT1254708B (it) 1995-10-09

Family

ID=37714672

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI910610A IT1254708B (it) 1990-03-08 1991-03-08 Procedimento a cuprato organico per preparare cefprozil

Country Status (12)

Country Link
US (1) US5043439A (it)
KR (1) KR0164855B1 (it)
CA (1) CA2037688A1 (it)
CZ (1) CZ282689B6 (it)
DK (1) DK40891A (it)
ES (1) ES2024380A6 (it)
FI (1) FI95709C (it)
GR (1) GR1001137B (it)
HU (1) HU211078B (it)
IT (1) IT1254708B (it)
NO (1) NO178577C (it)
OA (1) OA09744A (it)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5095107A (en) * 1990-11-05 1992-03-10 Eli Lilly And Company Process for cleavage of esters during the production of cephalosporins
DE4037841A1 (de) * 1990-11-28 1992-06-04 Bayer Ag Neue 3-substituierte cephalosporine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US5302711A (en) * 1992-02-18 1994-04-12 Eli Lilly And Company Ester cleavage process for use with β-lactams
IT1255458B (it) * 1992-05-11 1995-11-02 Col Marco Da Procedimento per la preparazione di derivati beta-lattamici alogenati

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1444224A (en) * 1972-07-21 1976-07-28 Glaxo Lab Ltd Cephalosporin compounds'
AR207327A1 (es) * 1974-02-06 1976-09-30 Lilly Co Eli Un procedimiento para preparar acidos 3-cefem 3-sulfonatos y sus esteres
US4870168A (en) * 1987-02-26 1989-09-26 Bristol-Myers Company 3-Unsaturated alkyl cephems from 3-triflyl cephems
US4855418A (en) * 1988-03-23 1989-08-08 Eli Lilly And Company Process for production of ceophalosporins

Also Published As

Publication number Publication date
CZ91691A3 (en) 1993-04-14
DK40891A (da) 1991-09-09
GR910100112A (en) 1992-06-30
HUT57218A (en) 1991-11-28
FI95709B (fi) 1995-11-30
NO178577C (no) 1996-04-24
NO178577B (no) 1996-01-15
OA09744A (en) 1993-11-30
DK40891D0 (da) 1991-03-07
CA2037688A1 (en) 1991-09-09
ES2024380A6 (es) 1992-02-16
HU910734D0 (en) 1991-09-30
FI911126A (fi) 1991-09-09
CZ282689B6 (cs) 1997-09-17
ITMI910610A1 (it) 1992-09-08
KR910016760A (ko) 1991-11-05
KR0164855B1 (ko) 1999-01-15
NO910894L (no) 1991-09-09
FI95709C (fi) 1996-03-11
HU211078B (en) 1995-10-30
GR1001137B (el) 1993-04-28
ITMI910610A0 (it) 1991-03-08
US5043439A (en) 1991-08-27
FI911126A0 (fi) 1991-03-06
NO910894D0 (no) 1991-03-07

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19950330