IT1218695B - Derivati di 1 piperazinil pirimidina loro preparazione e impiego in terapia e cosmesi - Google Patents
Derivati di 1 piperazinil pirimidina loro preparazione e impiego in terapia e cosmesiInfo
- Publication number
- IT1218695B IT1218695B IT68027/87A IT6802787A IT1218695B IT 1218695 B IT1218695 B IT 1218695B IT 68027/87 A IT68027/87 A IT 68027/87A IT 6802787 A IT6802787 A IT 6802787A IT 1218695 B IT1218695 B IT 1218695B
- Authority
- IT
- Italy
- Prior art keywords
- cosmetics
- therapy
- derivatives
- preparation
- piperazinyl pyrimidine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/50—Three nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
LU86695A LU86695A1 (fr) | 1986-12-01 | 1986-12-01 | Nouveaux derives de piperazinyl-1 pyrimidine,leur preparation et leur application en therapeutique et cosmetique |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8768027A0 IT8768027A0 (it) | 1987-11-30 |
IT1218695B true IT1218695B (it) | 1990-04-19 |
Family
ID=19730831
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT68027/87A IT1218695B (it) | 1986-12-01 | 1987-11-30 | Derivati di 1 piperazinil pirimidina loro preparazione e impiego in terapia e cosmesi |
Country Status (10)
Country | Link |
---|---|
US (2) | US4885296A (it) |
JP (1) | JPS63154677A (it) |
BE (1) | BE1000320A3 (it) |
CA (1) | CA1291479C (it) |
CH (1) | CH673649A5 (it) |
DE (1) | DE3740576A1 (it) |
FR (1) | FR2607505B1 (it) |
GB (1) | GB2198132B (it) |
IT (1) | IT1218695B (it) |
LU (1) | LU86695A1 (it) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5728714A (en) * | 1985-07-18 | 1998-03-17 | Proctor; Peter H. | Method for treating hair loss using tempo |
US5716947A (en) * | 1985-07-18 | 1998-02-10 | Proctor; Peter H. | Topical doxyl composition and method |
US5352442A (en) * | 1985-07-18 | 1994-10-04 | Proctor Peter H | Topical tempo |
US6150405A (en) * | 1985-07-18 | 2000-11-21 | Proctor; Peter H. | Hair loss treatment with ascorbates |
US5714482A (en) * | 1985-07-18 | 1998-02-03 | Proctor; Peter H. | Topical spin labels and method |
US5723502A (en) * | 1985-07-18 | 1998-03-03 | Proctor; Peter H. | Topical spin trap composition and method |
US5470876A (en) * | 1985-07-18 | 1995-11-28 | Proctor; Peter H. | Topical sod for treating hair loss |
US5472687A (en) * | 1985-07-18 | 1995-12-05 | Proctor; Peter H. | Topical pyridine N-oxides |
US5714510A (en) * | 1985-07-18 | 1998-02-03 | Proctor; Peter H. | Topical proxyl composition and method |
USRE35053E (en) * | 1985-09-12 | 1995-10-10 | The Upjohn Company | Amines useful in producing pharmaceutically active CNS compounds |
US5099019A (en) * | 1985-09-12 | 1992-03-24 | Upjohn Company | Amines useful in producing pharmaceutically active CNS compounds |
LU86695A1 (fr) * | 1986-12-01 | 1988-07-14 | Oreal | Nouveaux derives de piperazinyl-1 pyrimidine,leur preparation et leur application en therapeutique et cosmetique |
LU86969A1 (fr) * | 1987-08-12 | 1989-03-08 | Oreal | Association de derives de pyrimidine et de retinoides en composants separes pour induire et stimuler la croissance des cheveux et diminuer leur chute |
ATE110954T1 (de) * | 1988-01-29 | 1994-09-15 | Peter H Proctor | Haarwachstumanregung mit nitroxyd und anderen radikalen. |
DE3905364A1 (de) * | 1989-02-22 | 1990-08-23 | Hoechst Ag | Substituierte pyrimidin-derivate, verfahren zu ihrer herstellung und ihre verwendung als tool |
FR2653016B1 (fr) * | 1989-10-13 | 1994-09-16 | Oreal | Composition de lavage des matieres keratiniques, en particulier des cheveux et/ou de la peau. |
FR2662607B1 (fr) * | 1990-05-30 | 1992-08-28 | Oreal | Composition destinee a etre utilisee pour freiner la chute des cheveux et pour induire et stimuler leur croissance, contenant des derives d'alkyl-2 amino-4 (ou dialkyl-2-4) pyrimidine oxyde-3 . |
DE69108402T2 (de) * | 1990-11-14 | 1995-10-05 | Upjohn Co | 5-fluor-2,4,6-pyrimidinthiaminderivate zur verhinderung des haarsausfalls. |
DE4100975A1 (de) * | 1991-01-15 | 1992-07-16 | Weuffen Wolfgang | Kosmetische oder pharmazeutische zubereitungen zur verbesserung der haarqualitaet und foerderung des haarwachstums |
HUT64323A (en) * | 1992-06-09 | 1993-12-28 | Richter Gedeon Vegyeszet | Process for production new piperazinyl-bis(alkyl-amino)-pyrimidine derivatives |
HU214331B (hu) * | 1992-06-17 | 1998-03-02 | Gyógyszerkutató Intézet Kft. | Eljárás piperazin- és homopiperazinszármazékok és ezeket tartalmazó gyógyszerkészítmények előállítására |
US7326717B2 (en) | 2003-05-06 | 2008-02-05 | L'oreal | Pyrimidine n-oxide compounds for stimulating the growth of keratin fibers and/or reducing loss thereof |
US20050163811A1 (en) * | 2004-01-23 | 2005-07-28 | Richard Lee | Topical solutions comprising high concentrations of piperidinopyrimidine derivatives and methods of use thereof |
CN103204816B (zh) * | 2012-01-16 | 2016-04-27 | 中国人民解放军军事医学科学院毒物药物研究所 | 哌嗪基嘧啶类衍生物及其制备方法和用途 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3910928A (en) * | 1974-04-26 | 1975-10-07 | Upjohn Co | 3-(Cyanimino)-propionitriles |
US4166852A (en) * | 1974-08-09 | 1979-09-04 | Produits Chimiques Ugine Kuhlmann | Piperazino-pyrimidines and their use as spasmolytic agents |
US4139619A (en) * | 1976-05-24 | 1979-02-13 | The Upjohn Company | 6-Amino-4-(substituted amino)-1,2-dihydro-1-hydroxy-2-iminopyrimidine, topical compositions and process for hair growth |
EP0093770B1 (en) * | 1981-11-09 | 1991-06-19 | BAZZANO, Gail S | The use of retinoids and minoxidil (2,4-diamino-6-piperidino-pyrimidine-3-oxide) to increase the rate of growth of human scalp hair and to treat certain types of alopecias |
US4532240A (en) * | 1982-09-09 | 1985-07-30 | Warner-Lambert Company | Diaminopyrimidines |
US4725600A (en) * | 1984-07-13 | 1988-02-16 | Fujisawa Pharmaceutical Co., Ltd. | Pyrimidine compounds having activity as a cardiotonic anti-hypertensive cerebrovascular vasodilator and anti-platelet aggregation agent |
DE3670765D1 (en) * | 1985-01-25 | 1990-06-07 | Upjohn Co | Pyrimidinsulfate fuer haarwuchs. |
IT1186772B (it) * | 1985-10-10 | 1987-12-16 | Crinos Industria Farmaco | Composto ad attivita' pilostimolante |
US4729995A (en) * | 1986-04-21 | 1988-03-08 | Toyo Boseki Kabushiki Kaisha | Pyrimidine 2,4-dioxamate compounds and pharmaceutical compositions |
LU86695A1 (fr) * | 1986-12-01 | 1988-07-14 | Oreal | Nouveaux derives de piperazinyl-1 pyrimidine,leur preparation et leur application en therapeutique et cosmetique |
-
1986
- 1986-12-01 LU LU86695A patent/LU86695A1/fr unknown
-
1987
- 1987-11-30 DE DE19873740576 patent/DE3740576A1/de not_active Withdrawn
- 1987-11-30 CH CH4659/87A patent/CH673649A5/fr not_active IP Right Cessation
- 1987-11-30 IT IT68027/87A patent/IT1218695B/it active
- 1987-12-01 FR FR878716658A patent/FR2607505B1/fr not_active Expired
- 1987-12-01 BE BE8701366A patent/BE1000320A3/fr not_active IP Right Cessation
- 1987-12-01 US US07/126,799 patent/US4885296A/en not_active Expired - Fee Related
- 1987-12-01 GB GB8728053A patent/GB2198132B/en not_active Expired - Fee Related
- 1987-12-01 JP JP62301626A patent/JPS63154677A/ja active Pending
- 1987-12-01 CA CA000553282A patent/CA1291479C/fr not_active Expired - Fee Related
-
1989
- 1989-09-08 US US07/404,551 patent/US4916133A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
LU86695A1 (fr) | 1988-07-14 |
US4885296A (en) | 1989-12-05 |
US4916133A (en) | 1990-04-10 |
FR2607505A1 (fr) | 1988-06-03 |
DE3740576A1 (de) | 1988-06-09 |
CH673649A5 (it) | 1990-03-30 |
CA1291479C (fr) | 1991-10-29 |
GB2198132B (en) | 1990-07-25 |
GB8728053D0 (en) | 1988-01-06 |
BE1000320A3 (fr) | 1988-10-18 |
FR2607505B1 (fr) | 1989-04-28 |
JPS63154677A (ja) | 1988-06-27 |
GB2198132A (en) | 1988-06-08 |
IT8768027A0 (it) | 1987-11-30 |
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