IT1212821B - Derivati dell'acido fenil-etil-acetico ad attivita'antiinfiammatoria. - Google Patents

Derivati dell'acido fenil-etil-acetico ad attivita'antiinfiammatoria.

Info

Publication number
IT1212821B
IT1212821B IT8321456A IT2145683A IT1212821B IT 1212821 B IT1212821 B IT 1212821B IT 8321456 A IT8321456 A IT 8321456A IT 2145683 A IT2145683 A IT 2145683A IT 1212821 B IT1212821 B IT 1212821B
Authority
IT
Italy
Prior art keywords
fenyl
flammatory
activities
derivatives
ethyl
Prior art date
Application number
IT8321456A
Other languages
English (en)
Other versions
IT8321456A0 (it
Inventor
Alfonso Del Vecchio
Maria Grazia Sestini
Original Assignee
Scharper Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scharper Spa filed Critical Scharper Spa
Publication of IT8321456A0 publication Critical patent/IT8321456A0/it
Priority to IT8321456A priority Critical patent/IT1212821B/it
Priority to US06/614,754 priority patent/US4562287A/en
Priority to FR8408516A priority patent/FR2547726B1/fr
Priority to NL8401770A priority patent/NL8401770A/nl
Priority to GB08413984A priority patent/GB2142015B/en
Priority to DE3420387A priority patent/DE3420387A1/de
Priority to CH2692/84A priority patent/CH659058A5/de
Priority to BE0/213067A priority patent/BE899823A/fr
Priority to JP59113222A priority patent/JPS606637A/ja
Application granted granted Critical
Publication of IT1212821B publication Critical patent/IT1212821B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C07C57/42—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings having unsaturation outside the rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • C07C57/60—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings having unsaturation outside the rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT8321456A 1983-06-03 1983-06-03 Derivati dell'acido fenil-etil-acetico ad attivita'antiinfiammatoria. IT1212821B (it)

Priority Applications (9)

Application Number Priority Date Filing Date Title
IT8321456A IT1212821B (it) 1983-06-03 1983-06-03 Derivati dell'acido fenil-etil-acetico ad attivita'antiinfiammatoria.
US06/614,754 US4562287A (en) 1983-06-03 1984-05-29 2-(4-Biphenylyl)-4-hexenoic acid and derivatives thereof having anti-inflammatory activity
FR8408516A FR2547726B1 (fr) 1983-06-03 1984-05-30 Acide 2-(4-biphenylyl)-4-hexenoique et ses derives ayant une activite anti-inflammatoire
GB08413984A GB2142015B (en) 1983-06-03 1984-06-01 2-(4-biphenylyl)-4-hexenoic acids
NL8401770A NL8401770A (nl) 1983-06-03 1984-06-01 Therapeutische compositie met anti-anflammatoire en analgetische eigenschappen.
DE3420387A DE3420387A1 (de) 1983-06-03 1984-06-01 2-(4-biphenylyl)-4-hexenonsaeure und ihre derivate mit entzuendungshemmender wirksamkeit
CH2692/84A CH659058A5 (de) 1983-06-03 1984-06-01 2-(4-biphenylyl)-4'-halogen)-4-hexensaeuren, solche enthaltende heilmittel und verwendung von 2-(4-biphenylyl)-4-hexensaeurederivaten bei der herstellung von heilmitteln.
BE0/213067A BE899823A (fr) 1983-06-03 1984-06-04 Acide 2-(4-biphenylyl)-4-hexenoique et ses derives, doues d'une activite antiinflammatoire.
JP59113222A JPS606637A (ja) 1983-06-03 1984-06-04 炎症抑制作用を有する２−（４−ビフエニリル）−４−ヘキセン酸とその誘導体

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8321456A IT1212821B (it) 1983-06-03 1983-06-03 Derivati dell'acido fenil-etil-acetico ad attivita'antiinfiammatoria.

Publications (2)

Publication Number Publication Date
IT8321456A0 IT8321456A0 (it) 1983-06-03
IT1212821B true IT1212821B (it) 1989-11-30

Family

ID=11182041

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8321456A IT1212821B (it) 1983-06-03 1983-06-03 Derivati dell'acido fenil-etil-acetico ad attivita'antiinfiammatoria.

Country Status (9)

Country Link
US (1) US4562287A (it)
JP (1) JPS606637A (it)
BE (1) BE899823A (it)
CH (1) CH659058A5 (it)
DE (1) DE3420387A1 (it)
FR (1) FR2547726B1 (it)
GB (1) GB2142015B (it)
IT (1) IT1212821B (it)
NL (1) NL8401770A (it)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1201127A (en) * 1982-09-10 1986-02-25 Katsuhiro Uchida Biphenylylpropionic acid derivative, process for preparing the same and pharmaceutical composition containing the same
FR2869611B1 (fr) * 2004-05-03 2006-07-28 Merck Sante Soc Par Actions Si Derives de l'acide hexenoique, procedes pour leur preparation, compositions pharmaceutiques les contenant et applications en therapeutique
CN102826953B (zh) * 2012-07-24 2015-05-13 烟台万润精细化工股份有限公司 一种4-(烷基-3-烯)-(氟)苯衍生物的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB847779A (en) * 1958-04-14 1960-09-14 Vismara Francesco Spa 2-(4-biphenylyl)-í¸-hexenoic acid esters thereof
DE1128851B (de) * 1959-03-04 1962-05-03 Vismara Francesco Spa Verfahren zur Herstellung von 2-(4-Diphenylyl)-?-hexensaeure
GB1091403A (en) * 1964-01-24 1967-11-15 Boots Pure Drug Co Ltd Therapeutically active phenylalkane derivatives
US3483248A (en) * 1964-12-08 1969-12-09 Warner Lambert Pharmaceutical Preparation of 2-(4-biphenylyl) butyric acid
FR2215208A1 (en) * 1973-01-12 1974-08-23 Zambeletti Spa L Basic esters of 2-phenyl -4 - alkyl-4-hexanoic acids - useful as spasmolytics

Also Published As

Publication number Publication date
IT8321456A0 (it) 1983-06-03
JPS606637A (ja) 1985-01-14
GB8413984D0 (en) 1984-07-04
CH659058A5 (de) 1986-12-31
FR2547726A1 (fr) 1984-12-28
GB2142015B (en) 1987-01-21
FR2547726B1 (fr) 1986-08-29
BE899823A (fr) 1984-10-01
GB2142015A (en) 1985-01-09
DE3420387A1 (de) 1984-12-06
NL8401770A (nl) 1985-01-02
US4562287A (en) 1985-12-31

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