IT1209896B - Antibiotico bmg162-af2 procedimento per la sua produzione e medicinale antitumorale contenente il suddetto antibiotico come ingrediente attivo - Google Patents

Antibiotico bmg162-af2 procedimento per la sua produzione e medicinale antitumorale contenente il suddetto antibiotico come ingrediente attivo

Info

Publication number
IT1209896B
IT1209896B IT8149237A IT4923781A IT1209896B IT 1209896 B IT1209896 B IT 1209896B IT 8149237 A IT8149237 A IT 8149237A IT 4923781 A IT4923781 A IT 4923781A IT 1209896 B IT1209896 B IT 1209896B
Authority
IT
Italy
Prior art keywords
antibiotic
bmg162
procedure
production
active ingredient
Prior art date
Application number
IT8149237A
Other languages
English (en)
Other versions
IT8149237A0 (it
Inventor
Hamao Umezawa
Tomio Takeuchi
Hiroshi Naganawa
Hironobu Iinuma
Setsuko Kunimoto
Original Assignee
Zaidan Hojin Biseibutsu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zaidan Hojin Biseibutsu filed Critical Zaidan Hojin Biseibutsu
Publication of IT8149237A0 publication Critical patent/IT8149237A0/it
Application granted granted Critical
Publication of IT1209896B publication Critical patent/IT1209896B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/14Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/02Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/07Bacillus
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/832Bacillus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT8149237A 1980-09-08 1981-09-04 Antibiotico bmg162-af2 procedimento per la sua produzione e medicinale antitumorale contenente il suddetto antibiotico come ingrediente attivo IT1209896B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55123585A JPS5748957A (en) 1980-09-08 1980-09-08 Novel antibiotic bmg 162-af2, its preparation and carcinostatic agent comprising it as active ingredient

Publications (2)

Publication Number Publication Date
IT8149237A0 IT8149237A0 (it) 1981-09-04
IT1209896B true IT1209896B (it) 1989-08-30

Family

ID=14864227

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8149237A IT1209896B (it) 1980-09-08 1981-09-04 Antibiotico bmg162-af2 procedimento per la sua produzione e medicinale antitumorale contenente il suddetto antibiotico come ingrediente attivo

Country Status (18)

Country Link
US (2) US4416899A (it)
JP (1) JPS5748957A (it)
KR (1) KR870001373B1 (it)
AT (1) AT376239B (it)
AU (1) AU523222B2 (it)
BE (1) BE890229A (it)
CA (1) CA1175763A (it)
CH (1) CH655498B (it)
CS (1) CS226036B2 (it)
DE (1) DE3134353C2 (it)
DK (1) DK157890C (it)
ES (1) ES505256A0 (it)
FR (1) FR2489819A1 (it)
GB (1) GB2084999B (it)
HU (1) HU188077B (it)
IT (1) IT1209896B (it)
NL (1) NL8104069A (it)
SE (1) SE450836B (it)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57185254A (en) 1981-05-11 1982-11-15 Microbial Chem Res Found Novel carcinostatic substances and their preparation
JPS57192347A (en) * 1981-05-18 1982-11-26 Microbial Chem Res Found N-(4-(3-aminopropyl)aminobutyl)-2,2-dihydroxyethanamide and its synthesis
JPS5862152A (ja) * 1981-10-08 1983-04-13 Microbial Chem Res Found N−〔4−(3−アミノプロピル)アミノブチル〕−2−(ω−グアニジノ脂肪酸アミド)−2−ヒドロキシエタンアミドおよびその誘導体ならびにその製造法
JPS5942356A (ja) * 1982-09-02 1984-03-08 Microbial Chem Res Found スパガリン関連化合物およびその製造法
JPS60185758A (ja) * 1984-03-02 1985-09-21 Microbial Chem Res Found フエニレン基を有するスパガリン関連化合物およびその製造法
US4851446A (en) * 1984-11-13 1989-07-25 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Immunosuppressing method
JPS61134312A (ja) * 1984-12-06 1986-06-21 Microbial Chem Res Found 移植免疫抑制剤並びに抗アレルギ−剤
JPS61165322A (ja) * 1985-01-14 1986-07-26 Microbial Chem Res Found スパガリン類の注射用凍結乾燥製剤
ES2039213T3 (es) * 1986-04-04 1993-09-16 Microbial Chemistry Research Foundation Procedimiento para producir nuevos compuestos relacionados con espergualina.
JP2873340B2 (ja) * 1988-04-29 1999-03-24 武田薬品工業株式会社 抗生物質tan―1057,その製造法および用途
JPH0776204B2 (ja) * 1988-07-01 1995-08-16 寳酒造株式会社 スパガリン類の精製法
JPH0263181U (it) * 1988-10-27 1990-05-11
US4990536A (en) * 1989-04-03 1991-02-05 Nippon Kayaku Kabushiki Kaisha Immunopotentiator and spergualin-related compound therefor
US5162581A (en) * 1989-05-29 1992-11-10 Takaru Shuzo Co., Ltd. Crystalline deoxyspergualin, process for its preparation and suppository containing the same

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2998438A (en) * 1958-03-31 1961-08-29 Merck & Co Inc Eulicin and process for production
US3617448A (en) * 1967-10-03 1971-11-02 Research Corp Antibiotic and methods of producing and using it
US3743580A (en) * 1970-04-28 1973-07-03 Microbial Chem Res Found Antibiotic,negamycin,and processes for the preparation thereof
US4163796A (en) * 1977-12-14 1979-08-07 The Dow Chemical Company Stabilized aqueous amide antimicrobial composition
US4328229A (en) * 1978-03-29 1982-05-04 Taiho Pharmaceutical Company Limited Anti-cancer composition for delivering 5-fluorouracil to cancer tissues
US4226808A (en) * 1979-08-17 1980-10-07 Schering Corporation 1-Aryl-2-dihalogenodeuterioalkanoylamido-1,3-propanediol antibacterial agents

Also Published As

Publication number Publication date
IT8149237A0 (it) 1981-09-04
CA1175763A (en) 1984-10-09
DE3134353A1 (de) 1982-04-22
AU523222B2 (en) 1982-07-15
AT376239B (de) 1984-10-25
ATA386081A (de) 1984-03-15
HU188077B (en) 1986-03-28
US4416899A (en) 1983-11-22
KR870001373B1 (ko) 1987-07-24
BE890229A (fr) 1982-01-04
FR2489819A1 (fr) 1982-03-12
DE3134353C2 (de) 1986-03-13
FR2489819B1 (it) 1985-02-15
DK157890B (da) 1990-02-26
ES8302090A1 (es) 1983-01-01
JPS6316380B2 (it) 1988-04-08
CH655498B (it) 1986-04-30
SE450836B (sv) 1987-08-03
KR830007834A (ko) 1983-11-07
JPS5748957A (en) 1982-03-20
CS226036B2 (en) 1984-03-19
SE8105079L (sv) 1982-03-09
GB2084999A (en) 1982-04-21
US4474880A (en) 1984-10-02
DK394281A (da) 1982-03-09
AU7489281A (en) 1982-03-18
GB2084999B (en) 1984-06-13
ES505256A0 (es) 1983-01-01
NL8104069A (nl) 1982-04-01
DK157890C (da) 1990-07-23

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