IT1203952B - Processo per la preparazione di 1-alchil-3-cabossi-4-cinnoloni - Google Patents
Processo per la preparazione di 1-alchil-3-cabossi-4-cinnoloniInfo
- Publication number
- IT1203952B IT1203952B IT20230/87A IT2023087A IT1203952B IT 1203952 B IT1203952 B IT 1203952B IT 20230/87 A IT20230/87 A IT 20230/87A IT 2023087 A IT2023087 A IT 2023087A IT 1203952 B IT1203952 B IT 1203952B
- Authority
- IT
- Italy
- Prior art keywords
- preparation
- cinnoloni
- cabossi
- alchil
- hydrolysis
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 230000007062 hydrolysis Effects 0.000 abstract 2
- 238000006460 hydrolysis reaction Methods 0.000 abstract 2
- 150000001263 acyl chlorides Chemical class 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000029936 alkylation Effects 0.000 abstract 1
- 238000005804 alkylation reaction Methods 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 230000008878 coupling Effects 0.000 abstract 1
- 238000010168 coupling process Methods 0.000 abstract 1
- 238000005859 coupling reaction Methods 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- ZIUSEGSNTOUIPT-UHFFFAOYSA-N ethyl 2-cyanoacetate Chemical compound CCOC(=O)CC#N ZIUSEGSNTOUIPT-UHFFFAOYSA-N 0.000 abstract 1
- 238000003402 intramolecular cyclocondensation reaction Methods 0.000 abstract 1
- 150000002825 nitriles Chemical group 0.000 abstract 1
- 230000009466 transformation Effects 0.000 abstract 1
- 238000000844 transformation Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/28—Cinnolines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT20230/87A IT1203952B (it) | 1987-04-23 | 1987-04-23 | Processo per la preparazione di 1-alchil-3-cabossi-4-cinnoloni |
| US07/172,072 US4956460A (en) | 1987-04-23 | 1988-03-23 | Process for the preparation of 1-alkyl-3-carboxy-4-cinnolones |
| ES88105021T ES2063741T3 (es) | 1987-04-23 | 1988-03-28 | Un procedimiento para la preparacion de 1-alquil-3-carboxi-4-cinolonas. |
| DE3851854T DE3851854T2 (de) | 1987-04-23 | 1988-03-28 | Verfahren zur Herstellung von 1-Alkoxy-3-carboxy-4-cinnolonen. |
| EP88105021A EP0287853B1 (en) | 1987-04-23 | 1988-03-28 | A process for the preparation of 1-alkyl-3-carboxy-4-cinnolones. |
| AT88105021T ATE113037T1 (de) | 1987-04-23 | 1988-03-28 | Verfahren zur herstellung von 1-alkoxy-3-carboxy- 4-cinnolonen. |
| JP63092642A JPS63280084A (ja) | 1987-04-23 | 1988-04-14 | 1−アルキル−3−カルボキシ−4−シンノロン類の製造方法 |
| CA000564723A CA1317957C (en) | 1987-04-23 | 1988-04-21 | Process for the preparation of 1-alkyl-3-carboxy-4- cinnolones |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT20230/87A IT1203952B (it) | 1987-04-23 | 1987-04-23 | Processo per la preparazione di 1-alchil-3-cabossi-4-cinnoloni |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8720230A0 IT8720230A0 (it) | 1987-04-23 |
| IT1203952B true IT1203952B (it) | 1989-02-23 |
Family
ID=11164965
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT20230/87A IT1203952B (it) | 1987-04-23 | 1987-04-23 | Processo per la preparazione di 1-alchil-3-cabossi-4-cinnoloni |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4956460A (it) |
| EP (1) | EP0287853B1 (it) |
| JP (1) | JPS63280084A (it) |
| AT (1) | ATE113037T1 (it) |
| CA (1) | CA1317957C (it) |
| DE (1) | DE3851854T2 (it) |
| ES (1) | ES2063741T3 (it) |
| IT (1) | IT1203952B (it) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5183891A (en) * | 1989-11-09 | 1993-02-02 | Orsan | Method for the preparation of substituted 1,4-dihydro-4-oxo-cinnoline-3-carboxylic acid, esters and salts thereof, and intermediates used in their preparation |
| FR2672596B1 (fr) * | 1991-02-07 | 1995-07-13 | Roussel Uclaf | Nouveaux derives bicycliques azotes, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant. |
| EP0519140B1 (en) * | 1991-06-19 | 1998-07-29 | Hybrinova | Method for the preparation of substituted 1,4-dihydro-4-oxo-cinnoline-3-carboxylic acids, esters and salts thereof, and intermediates used in this method |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2797218A (en) * | 1953-08-13 | 1957-06-25 | May & Baker Ltd | Cinnoline derivatives |
| US3485845A (en) * | 1966-05-13 | 1969-12-23 | May & Baker Ltd | Methyl and ethyl 6- and 7-substituted 4-hydroxy-quinoline-3-carboxylates useful as coccidiostats |
| NL147145B (nl) * | 1969-02-04 | 1975-09-15 | Lilly Co Eli | Werkwijze ter bereiding van preparaten met antimicrobiele werking. |
| US3669965A (en) * | 1969-12-29 | 1972-06-13 | Lilly Co Eli | 1-lower alkyl or alkylene substituted-6,7-methylenedioxy-4(1h)-oxocinnoline-3-carboxylic acids and methods for making and using same |
| US3937704A (en) * | 1971-10-18 | 1976-02-10 | Warner-Lambert Company | 3-(methylsulfinyl)cinnolinones and their derivatives |
| DD207098A3 (de) * | 1981-12-22 | 1984-02-15 | Schmidt Hans Joerg | Verfahren zur herstellung von 1-alkyl-6,7-methylendioxy-4(1h)-oxo-cinnolin-3-carbonsaeuren |
| US4604134A (en) * | 1983-09-14 | 1986-08-05 | Lafarge Coppee | Pollen suppressant comprising a fused pyridazine |
| DE3418852A1 (de) * | 1984-05-21 | 1985-11-21 | Erhard Dr. 4400 Münster Severin | Fluoreszierende redoxindikatoren und ihre anwendung in der cytodiagnostik |
| JPH044264A (ja) * | 1990-04-20 | 1992-01-08 | Fuji Photo Film Co Ltd | X型無金属フタロシアニンの製造方法 |
-
1987
- 1987-04-23 IT IT20230/87A patent/IT1203952B/it active
-
1988
- 1988-03-23 US US07/172,072 patent/US4956460A/en not_active Expired - Fee Related
- 1988-03-28 DE DE3851854T patent/DE3851854T2/de not_active Expired - Fee Related
- 1988-03-28 ES ES88105021T patent/ES2063741T3/es not_active Expired - Lifetime
- 1988-03-28 EP EP88105021A patent/EP0287853B1/en not_active Expired - Lifetime
- 1988-03-28 AT AT88105021T patent/ATE113037T1/de not_active IP Right Cessation
- 1988-04-14 JP JP63092642A patent/JPS63280084A/ja active Pending
- 1988-04-21 CA CA000564723A patent/CA1317957C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JPS63280084A (ja) | 1988-11-17 |
| CA1317957C (en) | 1993-05-18 |
| DE3851854D1 (de) | 1994-11-24 |
| US4956460A (en) | 1990-09-11 |
| EP0287853B1 (en) | 1994-10-19 |
| EP0287853A3 (en) | 1990-07-18 |
| DE3851854T2 (de) | 1995-03-09 |
| EP0287853A2 (en) | 1988-10-26 |
| ATE113037T1 (de) | 1994-11-15 |
| ES2063741T3 (es) | 1995-01-16 |
| IT8720230A0 (it) | 1987-04-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19950427 |