IT1166627B - Impiego della 2-(2-tenoiltio)-propionilglicina in qualita' di agente mucolitico e antibroncospastico - Google Patents
Impiego della 2-(2-tenoiltio)-propionilglicina in qualita' di agente mucolitico e antibroncospasticoInfo
- Publication number
- IT1166627B IT1166627B IT2011179A IT2011179A IT1166627B IT 1166627 B IT1166627 B IT 1166627B IT 2011179 A IT2011179 A IT 2011179A IT 2011179 A IT2011179 A IT 2011179A IT 1166627 B IT1166627 B IT 1166627B
- Authority
- IT
- Italy
- Prior art keywords
- glycine
- propionyl
- thenoyl
- prepd
- thio
- Prior art date
Links
- YTGJWQPHMWSCST-UHFFFAOYSA-N Tiopronin Chemical compound CC(S)C(=O)NCC(O)=O YTGJWQPHMWSCST-UHFFFAOYSA-N 0.000 title abstract 2
- 108010058907 Tiopronin Proteins 0.000 title abstract 2
- 208000019423 liver disease Diseases 0.000 title abstract 2
- SIPWQPITYYSMFE-UHFFFAOYSA-N 2-[(2-methyl-3-oxo-3-thiophen-2-ylpropanethioyl)amino]acetic acid Chemical compound OC(=O)CNC(=S)C(C)C(=O)C1=CC=CS1 SIPWQPITYYSMFE-UHFFFAOYSA-N 0.000 title 1
- QIQITDHWZYEEPA-UHFFFAOYSA-N thiophene-2-carbonyl chloride Chemical compound ClC(=O)C1=CC=CS1 QIQITDHWZYEEPA-UHFFFAOYSA-N 0.000 title 1
- 241000699670 Mus sp. Species 0.000 abstract 2
- 241000700159 Rattus Species 0.000 abstract 2
- 230000001988 toxicity Effects 0.000 abstract 2
- 231100000419 toxicity Toxicity 0.000 abstract 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- 206010057190 Respiratory tract infections Diseases 0.000 abstract 1
- 230000001154 acute effect Effects 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000007918 intramuscular administration Methods 0.000 abstract 1
- 230000000510 mucolytic effect Effects 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- WOMAZEJKVZLLFE-UHFFFAOYSA-N propionylglycine Chemical compound CCC(=O)NCC(O)=O WOMAZEJKVZLLFE-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 abstract 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (17)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2011179A IT1166627B (it) | 1979-02-12 | 1979-02-12 | Impiego della 2-(2-tenoiltio)-propionilglicina in qualita' di agente mucolitico e antibroncospastico |
| CA000324110A CA1121825A (en) | 1978-04-11 | 1979-03-26 | 2-(2-thenoylthio)-propionylglycine: method for its preparation and pharmaceutical formulations containing said compound |
| FR7907633A FR2422657A1 (fr) | 1978-04-11 | 1979-03-27 | 2-(2-thenoylthio)-propionylglycine, procede pour sa preparation et compositions pharmaceutiques la contenant |
| DE2913211A DE2913211C2 (de) | 1978-04-11 | 1979-04-03 | 2-(2-Thenoylthio)-propionylglycin, Verfahren zu seiner Herstellung und es enthaltende pharmazeutische Mittel |
| CH318279A CH639380A5 (it) | 1978-04-11 | 1979-04-04 | 2-(2-tenoiltio)-propionilglicina, metodo per la sua preparazione e composizioni farmaceutiche che la contengono. |
| US06/026,933 US4242354A (en) | 1978-04-11 | 1979-04-04 | 2-(2-Thenolythio)-propionylglycine: method for its preparation and pharmaceutical formulations containing said compound |
| AT0249879A AT374194B (de) | 1978-04-11 | 1979-04-04 | Verfahren zur herstellung des neuen 2-(2-thenoylthio)-propionylglycin |
| AR276092A AR219379A1 (es) | 1978-04-11 | 1979-04-05 | Procedimiento para la preparacion de 2-(2-tenoiltio)-propionilglicina |
| NL7902700A NL7902700A (nl) | 1978-04-11 | 1979-04-05 | 2-(2-thenoylthio)-propionylglycine, werkwijze ter be- reiding ervan alsmede farmaceutische preparaten, die deze verbinding bevatten. |
| SE7903105A SE444940B (sv) | 1978-04-11 | 1979-04-06 | 2-(2-tenoyltio)-propionylglycin samt forfarande for framstellning derav |
| LU81132A LU81132A1 (fr) | 1978-04-11 | 1979-04-09 | 2-(2-thenoylthio)-propionylglycine,procede pour sa preparation et compositions pharmaceutiques la contenant |
| ES479423A ES479423A1 (es) | 1978-04-11 | 1979-04-09 | Procedimiento para la preparacion de 2-2-tenoiltio-propio- nil-glicina. |
| NO791205A NO149312C (no) | 1978-04-11 | 1979-04-10 | Analogifremgangsmaate ved fremstilling av terapeutisk aktivt 2-(2-tenoyltio)-propionylglycin |
| JP54044827A JPS5910673B2 (ja) | 1978-04-11 | 1979-04-11 | ２−（２−テノイルチオ）−プロピオニルグリシンまたはその塩およびその製法 |
| DK153179A DK148117C (da) | 1978-04-11 | 1979-04-11 | Analogifremgangsmaade til fremstilling af 2-(2-thenoylthio)-propionylglycin eller farmakologisk acceptable salte deraf med baser |
| GB7912768A GB2018756B (en) | 1978-04-11 | 1979-04-11 | 2-(2-thenoylthio)-propionylglycine: method for its preparation and pharmaceutical formulations containing said compound |
| IE788/79A IE47946B1 (en) | 1978-04-11 | 1979-08-08 | 2-(2-thenoylthio)-propionylglycine:method for its preparation and pharmaceutical formulations containing said compound |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2011179A IT1166627B (it) | 1979-02-12 | 1979-02-12 | Impiego della 2-(2-tenoiltio)-propionilglicina in qualita' di agente mucolitico e antibroncospastico |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT7920111A0 IT7920111A0 (it) | 1979-02-12 |
| IT1166627B true IT1166627B (it) | 1987-05-05 |
Family
ID=11163881
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT2011179A IT1166627B (it) | 1978-04-11 | 1979-02-12 | Impiego della 2-(2-tenoiltio)-propionilglicina in qualita' di agente mucolitico e antibroncospastico |
Country Status (1)
| Country | Link |
|---|---|
| IT (1) | IT1166627B (it) |
-
1979
- 1979-02-12 IT IT2011179A patent/IT1166627B/it active Protection Beyond IP Right Term
Also Published As
| Publication number | Publication date |
|---|---|
| IT7920111A0 (it) | 1979-02-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ITCP | Complementary protection certificate |
Free format text: CCP 69 |
|
| MEDD | Supplementary protection certificate for pharmaceutical products: granted |
Free format text: CCP 69, 19920325; MEDIOLANUM FARMACEUTICI S.R.L. |
|
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970226 |