IT1146156B - Derivati di acido 2 idrossi 5(1 idrossi 2 4(2 osso 1 benzimidazolinil) piperidino) etil benzoico e procedimento per la loro preparazione - Google Patents
Derivati di acido 2 idrossi 5(1 idrossi 2 4(2 osso 1 benzimidazolinil) piperidino) etil benzoico e procedimento per la loro preparazioneInfo
- Publication number
- IT1146156B IT1146156B IT48188/80A IT4818880A IT1146156B IT 1146156 B IT1146156 B IT 1146156B IT 48188/80 A IT48188/80 A IT 48188/80A IT 4818880 A IT4818880 A IT 4818880A IT 1146156 B IT1146156 B IT 1146156B
- Authority
- IT
- Italy
- Prior art keywords
- hydroxy
- benzimidazolinil
- piperidino
- bone
- procedure
- Prior art date
Links
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical class [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 title 2
- KZKRRZFCAYOXQE-UHFFFAOYSA-N 1$l^{2}-azinane Chemical class C1CC[N]CC1 KZKRRZFCAYOXQE-UHFFFAOYSA-N 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- 210000000988 bone and bone Anatomy 0.000 title 1
- 125000001495 ethyl group Chemical class [H]C([H])([H])C([H])([H])* 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/036,245 US4200755A (en) | 1979-05-04 | 1979-05-04 | 2-Hydroxy-5-[1-hydroxy-2-[4-(2-oxo-1-benzimidazolinyl)piperidino]ethyl]benzoic acid derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8048188A0 IT8048188A0 (it) | 1980-03-18 |
| IT1146156B true IT1146156B (it) | 1986-11-12 |
Family
ID=21887509
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT48188/80A IT1146156B (it) | 1979-05-04 | 1980-03-18 | Derivati di acido 2 idrossi 5(1 idrossi 2 4(2 osso 1 benzimidazolinil) piperidino) etil benzoico e procedimento per la loro preparazione |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US4200755A (it) |
| JP (1) | JPS55153783A (it) |
| AT (1) | AT375362B (it) |
| AU (1) | AU530654B2 (it) |
| BE (1) | BE883085A (it) |
| CA (1) | CA1138874A (it) |
| CH (1) | CH645373A5 (it) |
| DE (1) | DE3013928A1 (it) |
| DK (1) | DK193380A (it) |
| ES (1) | ES490666A0 (it) |
| FR (1) | FR2455599A1 (it) |
| GB (1) | GB2053194B (it) |
| IE (1) | IE49646B1 (it) |
| IL (1) | IL59580A (it) |
| IT (1) | IT1146156B (it) |
| NL (1) | NL8002070A (it) |
| NO (1) | NO152559C (it) |
| NZ (1) | NZ193084A (it) |
| PH (1) | PH15418A (it) |
| SE (1) | SE441447B (it) |
| ZA (1) | ZA801429B (it) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4264613A (en) * | 1979-08-01 | 1981-04-28 | Science Union Et Cie, Societe Francaise De Recherche Medicale | Piperidylbenzimidazolinone compounds |
| FR2469411A1 (fr) * | 1979-11-15 | 1981-05-22 | Science Union & Cie | Nouveaux derives de la piperidylbenzimidazolinone, leurs procedes de preparation et les compositions pharmaceutiques les renfermant |
| JPS58180481A (ja) * | 1982-04-15 | 1983-10-21 | Kyowa Hakko Kogyo Co Ltd | 新規なピペリジン誘導体 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE633495A (it) * | 1962-06-13 | |||
| US3318900A (en) * | 1964-05-06 | 1967-05-09 | Janssen Pharmaceutica Nv | Derivatives of benzimidazolinyl piperidine |
| US4080328A (en) * | 1971-07-13 | 1978-03-21 | Sumitomo Chemical Company, Limited | N-substituted heterocyclic derivatives and preparation thereof |
| US3818017A (en) * | 1973-01-04 | 1974-06-18 | Janssen Pharmaceutica Nv | 1-{8 1-(2-hydroxy-3-aryloxypropyl)-4-piperidyl{9 -2-benzimidazolinones and related compounds |
| US3894030A (en) * | 1973-01-04 | 1975-07-08 | Janssen Pharmaceutica Nv | 1-{8 1-(2-Hydroxy-3-aryloxypropyl)-4-piperidyl{9 -2-benzimidazolinones and related compounds |
| US3929801A (en) * | 1973-11-20 | 1975-12-30 | Janssen Pharmaceutica Nv | 2-Benzimidazolinones |
| JPS51125239A (en) * | 1975-03-05 | 1976-11-01 | Sumitomo Chem Co Ltd | Process for preparing new bytyrophenone derivatives |
| JPS5227775A (en) * | 1975-08-28 | 1977-03-02 | Sumitomo Chem Co Ltd | Preparation of novel acylhydrazone derivatives and their salts |
| JPS5359675A (en) * | 1976-11-08 | 1978-05-29 | Yoshitomi Pharmaceut Ind Ltd | Aminoalcohol derivatives |
| GR69650B (it) * | 1978-07-20 | 1982-07-07 | Science Union & Cie |
-
1979
- 1979-05-04 US US06/036,245 patent/US4200755A/en not_active Expired - Lifetime
-
1980
- 1980-03-05 IE IE442/80A patent/IE49646B1/en not_active IP Right Cessation
- 1980-03-06 AU AU56202/80A patent/AU530654B2/en not_active Expired
- 1980-03-10 NZ NZ193084A patent/NZ193084A/xx unknown
- 1980-03-11 ZA ZA00801429A patent/ZA801429B/xx unknown
- 1980-03-11 IL IL59580A patent/IL59580A/xx unknown
- 1980-03-14 PH PH23771A patent/PH15418A/en unknown
- 1980-03-18 IT IT48188/80A patent/IT1146156B/it active
- 1980-04-01 CA CA000348999A patent/CA1138874A/en not_active Expired
- 1980-04-09 NL NL8002070A patent/NL8002070A/nl not_active Application Discontinuation
- 1980-04-11 DE DE19803013928 patent/DE3013928A1/de not_active Ceased
- 1980-04-17 ES ES490666A patent/ES490666A0/es active Granted
- 1980-04-22 CH CH309280A patent/CH645373A5/de not_active IP Right Cessation
- 1980-04-25 GB GB8013780A patent/GB2053194B/en not_active Expired
- 1980-04-29 SE SE8003245A patent/SE441447B/sv not_active IP Right Cessation
- 1980-04-30 AT AT0232480A patent/AT375362B/de not_active IP Right Cessation
- 1980-04-30 FR FR8009851A patent/FR2455599A1/fr active Granted
- 1980-05-01 DK DK193380A patent/DK193380A/da not_active Application Discontinuation
- 1980-05-02 NO NO801298A patent/NO152559C/no unknown
- 1980-05-02 BE BE0/200445A patent/BE883085A/fr not_active IP Right Cessation
- 1980-05-02 JP JP5803580A patent/JPS55153783A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| NO152559B (no) | 1985-07-08 |
| CH645373A5 (de) | 1984-09-28 |
| IL59580A0 (en) | 1980-06-30 |
| IE800442L (en) | 1980-11-04 |
| NZ193084A (en) | 1982-06-29 |
| DE3013928A1 (de) | 1980-11-13 |
| JPS55153783A (en) | 1980-11-29 |
| DK193380A (da) | 1980-11-05 |
| ZA801429B (en) | 1980-12-31 |
| BE883085A (fr) | 1980-09-01 |
| ES8105000A1 (es) | 1981-05-16 |
| PH15418A (en) | 1983-01-07 |
| IT8048188A0 (it) | 1980-03-18 |
| IE49646B1 (en) | 1985-11-13 |
| FR2455599A1 (fr) | 1980-11-28 |
| IL59580A (en) | 1984-05-31 |
| FR2455599B1 (it) | 1983-09-23 |
| AT375362B (de) | 1984-07-25 |
| US4200755A (en) | 1980-04-29 |
| SE441447B (sv) | 1985-10-07 |
| NL8002070A (nl) | 1980-11-06 |
| ATA232480A (de) | 1983-12-15 |
| SE8003245L (sv) | 1980-11-05 |
| GB2053194A (en) | 1981-02-04 |
| ES490666A0 (es) | 1981-05-16 |
| CA1138874A (en) | 1983-01-04 |
| AU530654B2 (en) | 1983-07-21 |
| NO152559C (no) | 1985-10-16 |
| AU5620280A (en) | 1980-11-06 |
| NO801298L (no) | 1980-11-05 |
| GB2053194B (en) | 1982-11-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19990331 |