IT1117313B - PIRROL-1-CARBOXYLIC ACID DERIVATIVES AND PROCEDURE FOR THEIR PREPARATION - Google Patents

PIRROL-1-CARBOXYLIC ACID DERIVATIVES AND PROCEDURE FOR THEIR PREPARATION

Info

Publication number
IT1117313B
IT1117313B IT68630/77A IT6863077A IT1117313B IT 1117313 B IT1117313 B IT 1117313B IT 68630/77 A IT68630/77 A IT 68630/77A IT 6863077 A IT6863077 A IT 6863077A IT 1117313 B IT1117313 B IT 1117313B
Authority
IT
Italy
Prior art keywords
pirrol
procedure
preparation
carboxylic acid
acid derivatives
Prior art date
Application number
IT68630/77A
Other languages
Italian (it)
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27107410&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IT1117313(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US05/771,286 external-priority patent/US4089969A/en
Application filed by Syntex Inc filed Critical Syntex Inc
Application granted granted Critical
Publication of IT1117313B publication Critical patent/IT1117313B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
IT68630/77A 1976-07-14 1977-07-13 PIRROL-1-CARBOXYLIC ACID DERIVATIVES AND PROCEDURE FOR THEIR PREPARATION IT1117313B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US70490976A 1976-07-14 1976-07-14
US05/771,286 US4089969A (en) 1976-07-14 1977-02-23 5-Aroyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid derivatives and process for the production thereof

Publications (1)

Publication Number Publication Date
IT1117313B true IT1117313B (en) 1986-02-17

Family

ID=27107410

Family Applications (1)

Application Number Title Priority Date Filing Date
IT68630/77A IT1117313B (en) 1976-07-14 1977-07-13 PIRROL-1-CARBOXYLIC ACID DERIVATIVES AND PROCEDURE FOR THEIR PREPARATION

Country Status (27)

Country Link
JP (1) JPS539788A (en)
AR (1) AR224997A1 (en)
CA (1) CA1102809A (en)
CH (3) CH641458A5 (en)
CS (1) CS204954B2 (en)
DE (2) DE2731678A1 (en)
DK (1) DK151886C (en)
ES (2) ES460706A1 (en)
FI (1) FI63406C (en)
FR (2) FR2358406A1 (en)
GB (1) GB1554075A (en)
GR (1) GR61111B (en)
HK (1) HK15981A (en)
HU (1) HU174224B (en)
IE (1) IE45253B1 (en)
IL (2) IL52493A (en)
IT (1) IT1117313B (en)
MX (1) MX163202B (en)
MY (1) MY8100357A (en)
NL (2) NL186318C (en)
NO (1) NO147564C (en)
NZ (1) NZ184610A (en)
PL (4) PL109390B1 (en)
PT (1) PT66780B (en)
SE (1) SE434643B (en)
SU (1) SU695558A3 (en)
YU (1) YU40816B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4140698A (en) * 1977-07-25 1979-02-20 Syntex (Usa) Inc. 1,2-Dihydro-3H-pyrrolo[1,2-a]pyrrole-1-nitriles
JPS55124633A (en) * 1979-03-19 1980-09-25 Sohachi Takeuchi Manufacturing method of tubular vessel
US4344943A (en) * 1980-06-09 1982-08-17 Syntex (U.S.A.) Inc. 6-Chloro- or 6-bromo-1,2-dihydro-3H-pyrrolo[1,2-a]-pyrrole-1-carboxylic acids and derivatives thereof
US4353829A (en) * 1980-11-21 1982-10-12 Syntex (U.S.A.) Inc. Process for 5-aroylation of 1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic esters
JPS5910589A (en) * 1982-06-10 1984-01-20 メルク　エンド　カムパニー　インコーポレーテツド Antiinflammatory and analgesic novel 5-(pyrrol-2-oyl)-1,2-dihydro-3h-pyrrolo(1,2-a) pyrrole derivative
US4511724A (en) * 1982-06-10 1985-04-16 Merck & Co., Inc. 5-(Pyrrol-2-oyl)-1,2-dihydro-3H-pyrrolo [1,2-a]pyrrole derivatives as anti-inflammatory and analgesic agents
US4874871A (en) * 1987-03-25 1989-10-17 Syntex (U.S.A.) Inc. Process for preparing (+)-2,3-Dihydro-1H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid and related compounds
JPH0739418B2 (en) * 1987-09-10 1995-05-01 久光製薬株式会社 Novel 3-aroyl-6,7-dihydro-5H-pyrrolo [1,2-c] imidazole-7-carboxylic acid derivative
JP2649168B2 (en) * 1988-02-25 1997-09-03 久光製薬株式会社 Novel 5,6-diphenyl-1,2-dihydro-3H-pyrrolo [1,2-a] pyrrole-1-carboxylic acid derivatives
IT1250691B (en) * 1991-07-22 1995-04-21 Giancarlo Santus THERAPEUTIC COMPOSITIONS FOR INTRANASAL ADMINISTRATION INCLUDING KETOROLAC.
CA2123109A1 (en) * 1991-11-11 1993-05-27 Kanji Noda Ketorolac-containing fomentation
DE4300697C1 (en) * 1993-01-13 1994-05-19 Roemmers Sa New 2-pyrrolidino-ethyl ester of ketorolac - useful as analgesic, antiinflammatory and antipyretic agent with low ulcerogenicity
US5622948A (en) * 1994-12-01 1997-04-22 Syntex (U.S.A.) Inc. Pyrrole pyridazine and pyridazinone anti-inflammatory agents
JP2008210666A (en) * 2007-02-27 2008-09-11 Okamura Corp Lighting system in merchandise display shelf

Also Published As

Publication number Publication date
AU513384B2 (en) 1980-11-27
SE7708141L (en) 1978-01-15
DK151886C (en) 1988-06-06
CS204954B2 (en) 1981-04-30
NL7707651A (en) 1978-01-17
FR2358406B1 (en) 1981-04-17
FI63406C (en) 1983-06-10
DE2731678A1 (en) 1978-03-16
SU695558A3 (en) 1979-10-30
FR2375234A1 (en) 1978-07-21
IE45253L (en) 1978-01-14
FI772153A (en) 1978-01-15
PL109390B1 (en) 1980-05-31
CH646973A5 (en) 1984-12-28
NO772494L (en) 1978-01-17
HK15981A (en) 1981-05-01
ES470214A1 (en) 1979-09-16
PL124444B1 (en) 1983-01-31
PT66780A (en) 1977-08-01
CH646972A5 (en) 1984-12-28
AU2697577A (en) 1979-01-18
FR2358406A1 (en) 1978-02-10
YU40816B (en) 1986-06-30
FR2375234B1 (en) 1980-11-07
NL186318B (en) 1990-06-01
IL58779A0 (en) 1980-02-29
GR61111B (en) 1978-09-12
MY8100357A (en) 1981-12-31
FI63406B (en) 1983-02-28
PL199603A1 (en) 1978-04-24
NL930021I2 (en) 1997-03-03
YU172177A (en) 1983-09-30
DK307577A (en) 1978-01-15
CH641458A5 (en) 1984-02-29
NL930021I1 (en) 1993-05-03
IL52493A0 (en) 1977-10-31
DK151886B (en) 1988-01-11
IE45253B1 (en) 1982-07-14
DE2731678C2 (en) 1989-06-08
GB1554075A (en) 1979-10-17
JPS6254109B2 (en) 1987-11-13
DE2760330C2 (en) 1989-06-15
JPS539788A (en) 1978-01-28
NO147564B (en) 1983-01-24
MX163202B (en) 1992-02-20
PL124711B1 (en) 1983-02-28
NO147564C (en) 1983-05-18
PL124445B1 (en) 1983-01-31
AR224997A1 (en) 1982-02-15
ES460706A1 (en) 1978-12-01
PT66780B (en) 1978-12-18
HU174224B (en) 1979-11-28
IL52493A (en) 1982-02-28
NL186318C (en) 1990-11-01
CA1102809A (en) 1981-06-09
SE434643B (en) 1984-08-06
NZ184610A (en) 1979-03-28

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Legal Events

Date Code Title Description
ITCP Complementary protection certificate

Free format text: CCP 52

MEDD Supplementary protection certificate for pharmaceutical products: granted

Free format text: CCP 52, 19920311; SYNTEX (U.S.A.) INC.

ITCP Complementary protection certificate

Free format text: CCP 425

MEDM Supplementary protection certificate for pharmaceutical products: withdrawal of spc application

Free format text: CCP 425, 19930408; SYNTEX (U.S.A.) INC.

TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19950731