DK151886C - METHOD OF ANALOGUE FOR THE PREPARATION OF (DL) OR (1) 5-BENZOYL-1,2-DIHYDRO-3H-PYRROLOOE1,2-AAAPYRROL-1-CARBOXYL ACID ESTERS - Google Patents

METHOD OF ANALOGUE FOR THE PREPARATION OF (DL) OR (1) 5-BENZOYL-1,2-DIHYDRO-3H-PYRROLOOE1,2-AAAPYRROL-1-CARBOXYL ACID ESTERS

Info

Publication number
DK151886C
DK151886C DK307577A DK307577A DK151886C DK 151886 C DK151886 C DK 151886C DK 307577 A DK307577 A DK 307577A DK 307577 A DK307577 A DK 307577A DK 151886 C DK151886 C DK 151886C
Authority
DK
Denmark
Prior art keywords
pyrrolooe1
aaapyrrol
dihydro
analogue
benzoyl
Prior art date
Application number
DK307577A
Other languages
Danish (da)
Other versions
DK151886B (en
DK307577A (en
Inventor
Joseph M Muchowski
Arthur F Kluge
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27107410&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK151886(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US05/771,286 external-priority patent/US4089969A/en
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of DK307577A publication Critical patent/DK307577A/en
Priority to DK479980A priority Critical patent/DK151336C/en
Priority to DK479880A priority patent/DK151335C/en
Priority to DK479780A priority patent/DK152733C/en
Priority to DK480080A priority patent/DK151337C/en
Publication of DK151886B publication Critical patent/DK151886B/en
Application granted granted Critical
Publication of DK151886C publication Critical patent/DK151886C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
DK307577A 1976-07-14 1977-07-07 METHOD OF ANALOGUE FOR THE PREPARATION OF (DL) OR (1) 5-BENZOYL-1,2-DIHYDRO-3H-PYRROLOOE1,2-AAAPYRROL-1-CARBOXYL ACID ESTERS DK151886C (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
DK479980A DK151336C (en) 1976-07-14 1980-11-11 ANALOGY PROCEDURE FOR PREPARING ONE (DL) - OR (L) -5-BENZOYL-1,2-DIHYDRO-3H-PYRROL (1,2-A) PYRROL-1-CARBOXYLIC ACID
DK479880A DK151335C (en) 1976-07-14 1980-11-11 METHOD OF ANALOGUE FOR THE PREPARATION OF (DL) - OR (L) -5-BENZOYL-1,2-DIHYDRO-3H-PYRROLO (1,2-A) PYRROL-1-CARBOXYLIC ACID ESTERS OR SALTS
DK479780A DK152733C (en) 1976-07-14 1980-11-11 (D) -5-BENZOYL-1,2-DIHYDRO-3H-PYRROLOOE1,2-AAA-PYRROL-1-CARBOXYLIC ACID OR ESTERS OR SALTS THEREOF USED AS INTERMEDIATES (PRODUCTS OF DELIVERED PRODUCTS)
DK480080A DK151337C (en) 1976-07-14 1980-11-11 ANALOGY PROCEDURE FOR THE PREPARATION OF (DL) - OR (L) -5-BENZOYL-1,2-DIHYDRO-3H-PYRROLO (1,2-A) PYRROL-1-CARBOXYLIC ACID DERIVATIVES

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US70490976A 1976-07-14 1976-07-14
US70490976 1976-07-14
US05/771,286 US4089969A (en) 1976-07-14 1977-02-23 5-Aroyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid derivatives and process for the production thereof
US77128677 1977-02-23

Publications (3)

Publication Number Publication Date
DK307577A DK307577A (en) 1978-01-15
DK151886B DK151886B (en) 1988-01-11
DK151886C true DK151886C (en) 1988-06-06

Family

ID=27107410

Family Applications (1)

Application Number Title Priority Date Filing Date
DK307577A DK151886C (en) 1976-07-14 1977-07-07 METHOD OF ANALOGUE FOR THE PREPARATION OF (DL) OR (1) 5-BENZOYL-1,2-DIHYDRO-3H-PYRROLOOE1,2-AAAPYRROL-1-CARBOXYL ACID ESTERS

Country Status (27)

Country Link
JP (1) JPS539788A (en)
AR (1) AR224997A1 (en)
CA (1) CA1102809A (en)
CH (3) CH641458A5 (en)
CS (1) CS204954B2 (en)
DE (2) DE2731678A1 (en)
DK (1) DK151886C (en)
ES (2) ES460706A1 (en)
FI (1) FI63406C (en)
FR (2) FR2358406A1 (en)
GB (1) GB1554075A (en)
GR (1) GR61111B (en)
HK (1) HK15981A (en)
HU (1) HU174224B (en)
IE (1) IE45253B1 (en)
IL (2) IL52493A (en)
IT (1) IT1117313B (en)
MX (1) MX163202B (en)
MY (1) MY8100357A (en)
NL (2) NL186318C (en)
NO (1) NO147564C (en)
NZ (1) NZ184610A (en)
PL (4) PL124445B1 (en)
PT (1) PT66780B (en)
SE (1) SE434643B (en)
SU (1) SU695558A3 (en)
YU (1) YU40816B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4140698A (en) * 1977-07-25 1979-02-20 Syntex (Usa) Inc. 1,2-Dihydro-3H-pyrrolo[1,2-a]pyrrole-1-nitriles
JPS55124633A (en) * 1979-03-19 1980-09-25 Sohachi Takeuchi Manufacturing method of tubular vessel
US4344943A (en) * 1980-06-09 1982-08-17 Syntex (U.S.A.) Inc. 6-Chloro- or 6-bromo-1,2-dihydro-3H-pyrrolo[1,2-a]-pyrrole-1-carboxylic acids and derivatives thereof
US4353829A (en) * 1980-11-21 1982-10-12 Syntex (U.S.A.) Inc. Process for 5-aroylation of 1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic esters
US4511724A (en) * 1982-06-10 1985-04-16 Merck & Co., Inc. 5-(Pyrrol-2-oyl)-1,2-dihydro-3H-pyrrolo [1,2-a]pyrrole derivatives as anti-inflammatory and analgesic agents
JPS5910589A (en) * 1982-06-10 1984-01-20 メルク　エンド　カムパニー　インコーポレーテツド Antiinflammatory and analgesic novel 5-(pyrrol-2-oyl)-1,2-dihydro-3h-pyrrolo(1,2-a) pyrrole derivative
US4874871A (en) * 1987-03-25 1989-10-17 Syntex (U.S.A.) Inc. Process for preparing (+)-2,3-Dihydro-1H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid and related compounds
JPH0739418B2 (en) * 1987-09-10 1995-05-01 久光製薬株式会社 Novel 3-aroyl-6,7-dihydro-5H-pyrrolo [1,2-c] imidazole-7-carboxylic acid derivative
JP2649168B2 (en) * 1988-02-25 1997-09-03 久光製薬株式会社 Novel 5,6-diphenyl-1,2-dihydro-3H-pyrrolo [1,2-a] pyrrole-1-carboxylic acid derivatives
IT1250691B (en) * 1991-07-22 1995-04-21 Giancarlo Santus THERAPEUTIC COMPOSITIONS FOR INTRANASAL ADMINISTRATION INCLUDING KETOROLAC.
WO1993009768A1 (en) * 1991-11-11 1993-05-27 Hisamitsu Pharmaceutical Co., Inc. Fomentation containing ketorolac
DE4300697C1 (en) * 1993-01-13 1994-05-19 Roemmers Sa New 2-pyrrolidino-ethyl ester of ketorolac - useful as analgesic, antiinflammatory and antipyretic agent with low ulcerogenicity
US5622948A (en) * 1994-12-01 1997-04-22 Syntex (U.S.A.) Inc. Pyrrole pyridazine and pyridazinone anti-inflammatory agents
JP2008210666A (en) * 2007-02-27 2008-09-11 Okamura Corp Lighting system in merchandise display shelf

Also Published As

Publication number Publication date
YU172177A (en) 1983-09-30
IE45253B1 (en) 1982-07-14
NL186318C (en) 1990-11-01
DK151886B (en) 1988-01-11
NO147564C (en) 1983-05-18
AU513384B2 (en) 1980-11-27
NL7707651A (en) 1978-01-17
FI63406C (en) 1983-06-10
SE434643B (en) 1984-08-06
FR2358406B1 (en) 1981-04-17
YU40816B (en) 1986-06-30
CS204954B2 (en) 1981-04-30
ES470214A1 (en) 1979-09-16
NL930021I1 (en) 1993-05-03
NO772494L (en) 1978-01-17
PL109390B1 (en) 1980-05-31
NO147564B (en) 1983-01-24
FR2375234A1 (en) 1978-07-21
MX163202B (en) 1992-02-20
NL930021I2 (en) 1997-03-03
CH646973A5 (en) 1984-12-28
IE45253L (en) 1978-01-14
FI63406B (en) 1983-02-28
ES460706A1 (en) 1978-12-01
PL199603A1 (en) 1978-04-24
PT66780B (en) 1978-12-18
IL52493A (en) 1982-02-28
DE2731678A1 (en) 1978-03-16
PL124444B1 (en) 1983-01-31
HK15981A (en) 1981-05-01
NZ184610A (en) 1979-03-28
DE2731678C2 (en) 1989-06-08
JPS6254109B2 (en) 1987-11-13
AR224997A1 (en) 1982-02-15
IL58779A0 (en) 1980-02-29
CH641458A5 (en) 1984-02-29
MY8100357A (en) 1981-12-31
GB1554075A (en) 1979-10-17
FR2358406A1 (en) 1978-02-10
PL124711B1 (en) 1983-02-28
PT66780A (en) 1977-08-01
IL52493A0 (en) 1977-10-31
CH646972A5 (en) 1984-12-28
SE7708141L (en) 1978-01-15
PL124445B1 (en) 1983-01-31
GR61111B (en) 1978-09-12
SU695558A3 (en) 1979-10-30
HU174224B (en) 1979-11-28
IT1117313B (en) 1986-02-17
FR2375234B1 (en) 1980-11-07
AU2697577A (en) 1979-01-18
JPS539788A (en) 1978-01-28
DK307577A (en) 1978-01-15
FI772153A (en) 1978-01-15
CA1102809A (en) 1981-06-09
NL186318B (en) 1990-06-01
DE2760330C2 (en) 1989-06-15

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