IT1115158B - Acidi 4-tiazolidini-carbossilici anti-ipertenzione - Google Patents

Acidi 4-tiazolidini-carbossilici anti-ipertenzione

Info

Publication number
IT1115158B
IT1115158B IT21666/79A IT2166679A IT1115158B IT 1115158 B IT1115158 B IT 1115158B IT 21666/79 A IT21666/79 A IT 21666/79A IT 2166679 A IT2166679 A IT 2166679A IT 1115158 B IT1115158 B IT 1115158B
Authority
IT
Italy
Prior art keywords
thiazolidini
hypertention
carboxylic acids
carboxylic
acids
Prior art date
Application number
IT21666/79A
Other languages
English (en)
Italian (it)
Other versions
IT7921666A0 (it
Original Assignee
Santen Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP4163278A external-priority patent/JPS54135768A/ja
Priority claimed from JP4965778A external-priority patent/JPS54148783A/ja
Priority claimed from JP8111678A external-priority patent/JPS557255A/ja
Application filed by Santen Pharmaceutical Co Ltd filed Critical Santen Pharmaceutical Co Ltd
Publication of IT7921666A0 publication Critical patent/IT7921666A0/it
Application granted granted Critical
Publication of IT1115158B publication Critical patent/IT1115158B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
IT21666/79A 1978-04-08 1979-04-06 Acidi 4-tiazolidini-carbossilici anti-ipertenzione IT1115158B (it)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP4163278A JPS54135768A (en) 1978-04-08 1978-04-08 Thiazolidine derivative
JP4965778A JPS54148783A (en) 1978-04-25 1978-04-25 Thiazolidine derivative
JP8111678A JPS557255A (en) 1978-07-03 1978-07-03 Thiazolidine derivative

Publications (2)

Publication Number Publication Date
IT7921666A0 IT7921666A0 (it) 1979-04-06
IT1115158B true IT1115158B (it) 1986-02-03

Family

ID=27290900

Family Applications (1)

Application Number Title Priority Date Filing Date
IT21666/79A IT1115158B (it) 1978-04-08 1979-04-06 Acidi 4-tiazolidini-carbossilici anti-ipertenzione

Country Status (11)

Country Link
US (5) US4430344A (show.php)
AU (1) AU528115B2 (show.php)
CA (1) CA1127157A (show.php)
CH (1) CH649293A5 (show.php)
DE (1) DE2914059C2 (show.php)
ES (1) ES479410A1 (show.php)
FR (1) FR2421889A1 (show.php)
GB (1) GB2018248B (show.php)
IT (1) IT1115158B (show.php)
NL (1) NL7902710A (show.php)
SE (1) SE434943B (show.php)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA794723B (en) * 1978-09-11 1980-08-27 Univ Miami Anti-hypertensive agents
US4483861A (en) * 1978-10-31 1984-11-20 Santen Pharmaceutical Co., Ltd. Antihypertensive sulfur-containing compounds
JPS56139455A (en) 1980-04-02 1981-10-30 Santen Pharmaceut Co Ltd Sulfur-containing acylaminoacid
JPS5756425A (en) * 1980-09-20 1982-04-05 Santen Pharmaceut Co Ltd Hypotensor
DE3152643A1 (de) * 1980-12-29 1982-12-16 Santen Pharmaceutical Co Ltd Heterocyclic 5-membered ring compounds
JPS57112381A (en) * 1980-12-29 1982-07-13 Santen Pharmaceut Co Ltd Five-membered heterocyclic compound
JPS57142962A (en) * 1981-02-28 1982-09-03 Santen Pharmaceut Co Ltd Cyclodextrin clathrate compound of sulfur-containing compound
DE3134933A1 (de) * 1981-09-03 1983-03-31 Hoechst Ag, 6230 Frankfurt "harnstoffderivate, verfahren zu ihrer herstellung und diese enthaltende medikamente sowie deren verwendung"
IT1153963B (it) * 1982-03-22 1987-01-21 Montedison Spa Derivati dell'acido 2 0 4-tiazolidin-carbossilico 3-acil sostituiti ad azione fitoregolatrice e biostimolanti
IT1191109B (it) * 1982-12-03 1988-02-24 Simes Derivati di acidi aminopiridincarbossilici,loro metodo di sintesi e composizioni farmaceutiche che li contengono
US4631343A (en) * 1983-11-07 1986-12-23 Eli Lilly And Company Cyanopyrazole intermediates
GB2164333B (en) * 1984-07-27 1988-11-16 Boehringer Biochemia Srl Antitussive and mucus regulating 2-substituted thiazolidines
IT1196485B (it) * 1986-07-14 1988-11-16 Zambon Spa Derivati dell'acido tiazolidin-4-carbossilico ad attivita' farmaceutica
CN1030415A (zh) * 1987-02-20 1989-01-18 山之内制药株式会社 饱和的杂环碳酰胺衍生物和它的制备方法
IT1241415B (it) * 1990-03-05 1994-01-14 Yason Srl Derivato dell'acido s-(2-tenoil)-tiolattico ad attivita' farmacologica
CA2178130C (en) * 1995-06-05 2002-04-02 Hiroshi Ikawa Method of producing 2-naphthamide derivative, and compounds for producing 2-naphthamide derivative
US6083966A (en) 1998-08-31 2000-07-04 University Of Florida Thiazoline acid derivatives
CN1585639A (zh) * 1998-09-21 2005-02-23 佛罗里达大学研究基金会 抗疟疾制剂
US20040044220A1 (en) * 2002-08-22 2004-03-04 University Of Florida Antioxidant and radical scavenging activity of synthetic analogs of desferrithiocin
WO2004017959A2 (en) * 2002-08-22 2004-03-04 University Of Florida Antioxidant and radical scavenging activity of synthetic analogs of desferrithiocin
US7687468B2 (en) * 2003-05-14 2010-03-30 Viacell, LLC. Rejuvenation of stored blood
AU2003270473A1 (en) * 2003-09-09 2005-04-27 University Of Florida Desferrithiocin derivatives and their use as iron chelators
BRPI0610644B8 (pt) * 2005-04-04 2021-05-25 Univ Florida composto e composição farmacêutica que compreende tal composto e um veículo ou diluente farmaceuticamente aceitável.
NZ579994A (en) 2007-03-15 2011-09-30 Univ Florida Desferrithiocin polyether analogues useful in the treatment of pathological conditions responsive to chelation or sequestration of trivalent metal
EP2790697B1 (en) 2011-12-16 2019-10-23 University of Florida Research Foundation, Inc. Uses of 4'-desferrithiocin analogs
RU2526619C2 (ru) * 2012-12-12 2014-08-27 Федеральное государственное бюджетное учреждение науки Институт высокомолекулярных соединений Российской академии наук Способ получения (2r,4r)-2-алкил-3-(2-меркаптобензоил)-1,3-тиазолидин-4-карбоновых кислот
WO2015077655A1 (en) 2013-11-22 2015-05-28 University Of Florida Research Foundation, Inc. Desferrithiocin analogs and uses thereof
WO2016176343A1 (en) 2015-04-27 2016-11-03 University Of Florida Research Foundation, Incorporated Metabolically programmed metal chelators and uses thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3592905A (en) * 1969-10-30 1971-07-13 Merck & Co Inc Therapeutic methods
FR2356423A1 (fr) * 1976-07-01 1978-01-27 Oeriu Simion Derives de l'acide thiazolidinecarboxylique, leur preparation et leur application comme medicaments
AU518147B2 (en) * 1976-12-03 1981-09-17 E.R. Squibb & Sons, Inc. Derivatives of thiazolidine, thiazine and morpholine carboxylic acids
US4192878A (en) 1976-12-03 1980-03-11 E. R. Squibb & Sons, Inc. Derivatives of thiazolidinecarboxylic acids and related acids
JPS5834474B2 (ja) 1977-06-29 1983-07-27 ウェルファイド株式会社 チアゾリジン誘導体の製造法
JPS6047264B2 (ja) * 1977-08-15 1985-10-21 ウェルファイド株式会社 チアゾリジン誘導体
FR2395998A1 (fr) 1977-06-29 1979-01-26 Yoshitomi Pharmaceutical Nouveaux derives de la thiazolidine et leur application dans le traitement de l'hypertension
FR2404635A1 (fr) * 1977-09-28 1979-04-27 Science Union & Cie Nouveaux thioproprionylamides, leurs procedures d'obtention et leur emploi en therapeutique
US4282235A (en) * 1978-05-22 1981-08-04 E. R. Squibb & Sons, Inc. Derivatives of thiazolidinecarboxylic acids and related acids
US4347371A (en) * 1978-12-30 1982-08-31 Santen Pharmaceutical Co., Ltd. Disulfide compounds
US4374249A (en) * 1980-12-23 1983-02-15 American Cyanamid Company [4R]-3-(ω-Aroylpropionyl)-4-thiazolidinecarboxylic acids and esters

Also Published As

Publication number Publication date
US4423054A (en) 1983-12-27
ES479410A1 (es) 1980-08-16
US4457935A (en) 1984-07-03
US4356183A (en) 1982-10-26
DE2914059A1 (de) 1979-10-25
FR2421889A1 (fr) 1979-11-02
AU4544479A (en) 1979-10-18
DE2914059C2 (de) 1984-09-06
FR2421889B1 (show.php) 1982-11-19
US4430344A (en) 1984-02-07
SE434943B (sv) 1984-08-27
CH649293A5 (de) 1985-05-15
AU528115B2 (en) 1983-04-14
SE7902910L (sv) 1979-10-09
NL7902710A (nl) 1979-10-10
GB2018248A (en) 1979-10-17
IT7921666A0 (it) 1979-04-06
CA1127157A (en) 1982-07-06
US4386096A (en) 1983-05-31
GB2018248B (en) 1982-10-27

Similar Documents

Publication Publication Date Title
IT1115158B (it) Acidi 4-tiazolidini-carbossilici anti-ipertenzione
IT1122379B (it) Acidi 2-pirrolidincarbossilici 5-sostituiti,antiipertensivi
DK136579A (da) Thioetiansyrederivater
IT1211147B (it) Acidi treo-3-ammino-2-idrossibutanoilammi no-acetici utili come farmaci.
IT1120442B (it) Procedimento per produrre acidi arilpiruvici
DK317178A (da) Phenyleddikesyrederivater
FI791502A7 (fi) Anordning foer kylning av cylinderlocket i en fyrtaktdieselmotor
FI790090A7 (fi) Foerfarande foer foerbaettring av haollfastheten hos vaota glasfibermattor framstaellda medelst vaotlaeggningsprocessen
FI64206B (fi) Anordning foer snabbt skiljande av valsarna i en kalander
FI790387A7 (fi) Anordning foer indentifiering av skivsidan i en videoskivspelare
FI790703A7 (fi) Anordning foer reglering av foer reglering av foerarsitsen i motorfordon
IT1104709B (it) Acidi alfa-fluorometil-alfa-ammino alcanoici
FI781164A7 (fi) Anordning foer upphaengning av koepkassar i en knippa
FI791753A7 (fi) Anordning foer styrning av raelsfordon i dragkoppling
FI793044A7 (fi) Koppling foer aostadkommande av en styrstorhet foer styrning av oeverfoeringsgrader hos elektroniskt styrbara foerstaerknings- och daempningsorgan
FI65787B (fi) Foerfarande foer foerbaettring av loesningstillstaondet hos vikosmassor
FI782579A7 (fi) Vinghjul hos en centifugalflaekt
FI791445A7 (fi) Avskalningsanordning foer avlaegsnande av i vaetskor flytande foeroreningar
IT7830114A0 (it) Acidi alfa-fenossi-propion-tiolici.
FI790329A7 (fi) Foerfarande foer framstaellning av 1-naftylaettiksyraderivat
FI792586A7 (fi) Alfa-aminofenylaettikssyraderivat
FI791311A7 (fi) Foerfaringssaett foer bestaemmande av ytvikten hos en mineralullsmatta
FI782578A7 (fi) Vinghjul hos en centrifugalflaekt saerskilt en hoegtrycksflaekt
TR20909A (tr) Ensektisid pirazol-4-metanol esterler
FI792886A7 (fi) Anordning foer upprepad automatisk bestaemning av vattenavgivningsfoermaogan hos en fiberaemnessuspension

Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19940325