IT1093255B - Derivati fenossialcanolaminici - Google Patents
Derivati fenossialcanolaminiciInfo
- Publication number
- IT1093255B IT1093255B IT1944978A IT1944978A IT1093255B IT 1093255 B IT1093255 B IT 1093255B IT 1944978 A IT1944978 A IT 1944978A IT 1944978 A IT1944978 A IT 1944978A IT 1093255 B IT1093255 B IT 1093255B
- Authority
- IT
- Italy
- Prior art keywords
- substd
- opt
- alkyl
- derivs
- aryl
- Prior art date
Links
- SCKQUWRORFAPMX-UHFFFAOYSA-N 3-amino-1-phenoxy-1-phenylpropan-2-ol Chemical compound C=1C=CC=CC=1C(C(O)CN)OC1=CC=CC=C1 SCKQUWRORFAPMX-UHFFFAOYSA-N 0.000 title 1
- 239000000935 antidepressant agent Substances 0.000 title 1
- 229940005513 antidepressants Drugs 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 125000003118 aryl group Chemical group 0.000 abstract 4
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- WUGQZFFCHPXWKQ-UHFFFAOYSA-N Propanolamine Chemical compound NCCCO WUGQZFFCHPXWKQ-UHFFFAOYSA-N 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000000816 ethylene group Chemical group [H]C([H])([*:1])C([H])([H])[*:2] 0.000 abstract 1
- 125000001188 haloalkyl group Chemical group 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000002950 monocyclic group Chemical group 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 125000006237 oxymethylenoxy group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/27—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
- C07C205/32—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups bound to acyclic carbon atoms and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/27—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
- C07C205/35—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C07C205/36—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system
- C07C205/37—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/215—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring having unsaturation outside the six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/41—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydrogenolysis or reduction of carboxylic groups or functional derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
- C07D265/32—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings with oxygen atoms directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
- C07D265/32—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings with oxygen atoms directly attached to ring carbon atoms
- C07D265/33—Two oxygen atoms, in positions 3 and 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/24—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/58—Radicals substituted by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (32)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1944978A IT1093255B (it) | 1978-01-20 | 1978-01-20 | Derivati fenossialcanolaminici |
| IL56369A IL56369A (en) | 1978-01-20 | 1979-01-04 | Alpha-phenoxybenzyl propanolamine derivatives,their preparation and pharmaceutical compositions comprising them |
| US06/001,604 US4229449A (en) | 1978-01-20 | 1979-01-08 | Substituted morpholine derivatives and compositions |
| CY1172A CY1172A (en) | 1978-01-20 | 1979-01-11 | Substituted propanolamine and morpholine derivatives |
| GB7901130A GB2014981B (en) | 1978-01-20 | 1979-01-11 | Substituted propanolamine and morpholine derivatives |
| AU43327/79A AU525954B2 (en) | 1978-01-20 | 1979-01-12 | Substituted propanolamine and morpholine derivatives |
| DE2901032A DE2901032C2 (de) | 1978-01-20 | 1979-01-12 | Substituierte Morpholin-Derivate und deren Verwendung |
| DE1998175005 DE19875005I2 (de) | 1978-01-20 | 1979-01-12 | Substituierte Morpholin-Derivate und deren Verwendung |
| SI7910096A SI7910096A8 (sl) | 1978-01-20 | 1979-01-17 | Postopek za pripravo novih morfolinskih spojin |
| NZ189418A NZ189418A (en) | 1978-01-20 | 1979-01-17 | Propanolamine and morpholine derivatives pharmaceutical compositions |
| YU96/79A YU42094B (en) | 1978-01-20 | 1979-01-17 | Process for obtaining new morpnoline compounds |
| NL7900412A NL190327C (nl) | 1978-01-20 | 1979-01-18 | Gesubstitueerd 2-(fenoxymethyl)morfolinederivaat met anti-depressieve werking, werkwijze voor de bereiding daarvan, alsmede farmaceutisch preparaat, dat een dergelijk morfolinederivaat bevat. |
| DK022679A DK156565C (da) | 1978-01-20 | 1979-01-18 | Analogifremgangsmaade til fremstilling af substituerede morpholinderivater |
| ZA79215A ZA79215B (en) | 1978-01-20 | 1979-01-18 | Substituted propanolamine and morpholine derivatives and process for their preparation |
| FI790177A FI71135C (fi) | 1978-01-20 | 1979-01-19 | Foerfarande foer framstaellning av farmakologiskt aktiva substituerade morfolinderivat |
| FR7901413A FR2442839A1 (fr) | 1978-01-20 | 1979-01-19 | Derives substitues de morpholine utiles comme medicaments et procede de leur preparation |
| SE7900498A SE446727B (sv) | 1978-01-20 | 1979-01-19 | Substituerade morfolinderivat och farmaceutisk komposition derav |
| CA319,931A CA1128942A (en) | 1978-01-20 | 1979-01-19 | Substituted propanolamine and morpholine derivatives and process for their preparation |
| NO790205A NO146953C (no) | 1978-01-20 | 1979-01-19 | Analogifremgangsmaate ved fremstilling av substituerte propanolamin- og morfolinderivater |
| AT0040679A AT371813B (de) | 1978-01-20 | 1979-01-19 | Verfahren zum herstellen von neuen substituierten propanolamin- und morpholinderivaten und von deren isomeren und salzen |
| CS45779A CS207696B2 (cs) | 1978-01-20 | 1979-01-19 | Způsob výroby substituovaných propanolamínových a morfolínových derivátů |
| CH582/79A CH650245A5 (de) | 1978-01-20 | 1979-01-19 | Substituierte propanolamin- und morpholinderivate und verfahren zu deren herstellung. |
| BE0/192991A BE873596A (fr) | 1978-01-20 | 1979-01-19 | Propanolamines et morpholines substituees et procede de preparation. |
| JP449479A JPS54148739A (en) | 1978-01-20 | 1979-01-20 | Substituted propanolamine and morpholine derivative |
| IE107/79A IE47727B1 (en) | 1978-01-20 | 1979-01-30 | Substituted propanolamine and morpholine derivatives |
| FR7922678A FR2430412B1 (fr) | 1978-01-20 | 1979-09-11 | Derives substitues de propanolamine utiles comme medicaments et procede de leur preparation |
| US06/161,509 US4271160A (en) | 1978-01-20 | 1980-06-20 | Substituted morpholine derivatives and pharmaceutical compositions |
| KE3243A KE3243A (en) | 1978-01-20 | 1982-10-25 | Substituted propanolamine and morpholine derivatives |
| HK57/83A HK5783A (en) | 1978-01-20 | 1983-02-08 | Substituted propanolamine and morpholine derivatives |
| MY8418A MY8400018A (en) | 1978-01-20 | 1984-12-31 | Substituted propanolamine and morpholine derivatives |
| CS914133A CS413391A3 (en) | 1978-01-20 | 1991-12-30 | Substituted propanolamine and morpholine derivatives |
| BG098513A BG61056B2 (bg) | 1978-01-20 | 1994-02-22 | Заместени пропаноламинови и морфолинови производни |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1944978A IT1093255B (it) | 1978-01-20 | 1978-01-20 | Derivati fenossialcanolaminici |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT7819449A0 IT7819449A0 (it) | 1978-01-20 |
| IT1093255B true IT1093255B (it) | 1985-07-19 |
Family
ID=11158097
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT1944978A IT1093255B (it) | 1978-01-20 | 1978-01-20 | Derivati fenossialcanolaminici |
Country Status (3)
| Country | Link |
|---|---|
| BE (1) | BE873596A (it) |
| IT (1) | IT1093255B (it) |
| ZA (1) | ZA79215B (it) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AP2006003771A0 (en) | 2004-04-30 | 2006-10-31 | Warner Lambert Co | Substituted morpholine compounds for the treatmentof central nervous system disorders |
-
1978
- 1978-01-20 IT IT1944978A patent/IT1093255B/it active
-
1979
- 1979-01-18 ZA ZA79215A patent/ZA79215B/xx unknown
- 1979-01-19 BE BE0/192991A patent/BE873596A/fr not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ZA79215B (en) | 1980-03-26 |
| BE873596A (fr) | 1979-07-19 |
| IT7819449A0 (it) | 1978-01-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970124 |