IS7615A - Bísýklískar píperidín afleiður sem mótlyf af CCR1flakkboða viðtakanum - Google Patents

Bísýklískar píperidín afleiður sem mótlyf af CCR1flakkboða viðtakanum

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Publication number
IS7615A
IS7615A IS7615A IS7615A IS7615A IS 7615 A IS7615 A IS 7615A IS 7615 A IS7615 A IS 7615A IS 7615 A IS7615 A IS 7615A IS 7615 A IS7615 A IS 7615A
Authority
IS
Iceland
Prior art keywords
ccr1
antagonists
piperidine derivatives
antagonist receptor
bicyclic piperidine
Prior art date
Application number
IS7615A
Other languages
English (en)
Inventor
Cook Blumberg Laura
Frank Brown Matthew
Merrill Hayward Matthew
Stanley Poss Christopher
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of IS7615A publication Critical patent/IS7615A/is

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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
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    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
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    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
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    • C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Obesity (AREA)
  • Neurosurgery (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biotechnology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Transplantation (AREA)
IS7615A 2002-07-18 2004-12-23 Bísýklískar píperidín afleiður sem mótlyf af CCR1flakkboða viðtakanum IS7615A (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39726302P 2002-07-18 2002-07-18
PCT/IB2003/003155 WO2004009588A1 (en) 2002-07-18 2003-07-07 Bicyclic piperidine derivatives as antagonists of the ccr1 chemokine receptor

Publications (1)

Publication Number Publication Date
IS7615A true IS7615A (is) 2004-12-23

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IS7615A IS7615A (is) 2002-07-18 2004-12-23 Bísýklískar píperidín afleiður sem mótlyf af CCR1flakkboða viðtakanum

Country Status (24)

Country Link
US (1) US20040063688A1 (is)
EP (1) EP1525201A1 (is)
JP (1) JP2005533845A (is)
KR (1) KR20050028036A (is)
CN (1) CN1668614A (is)
AP (1) AP2005003196A0 (is)
AR (1) AR040586A1 (is)
AU (1) AU2003281527A1 (is)
BR (1) BR0312699A (is)
CA (1) CA2492110A1 (is)
EA (1) EA200500033A1 (is)
EC (1) ECSP055548A (is)
GT (1) GT200300147A (is)
IL (1) IL166075A0 (is)
IS (1) IS7615A (is)
MA (1) MA27327A1 (is)
MX (1) MXPA05000757A (is)
OA (1) OA12886A (is)
PA (1) PA8577401A1 (is)
PE (1) PE20040668A1 (is)
TN (1) TNSN05013A1 (is)
TW (1) TW200401639A (is)
UY (1) UY27896A1 (is)
WO (1) WO2004009588A1 (is)

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UA82517C2 (uk) * 2003-06-24 2008-04-25 Ньюросерч А/С Нові похідні 8-аза-біцикло[3.2.1]октану та їх застосування як інгібіторів ресорбції моноамінових медіаторів
US7230022B2 (en) 2004-02-19 2007-06-12 Bristol-Myers Squibb Company Substituted fused bicyclic amines as modulators of chemokine receptor activity
US7381738B2 (en) 2004-02-19 2008-06-03 Bristol-Myers Squibb Company Substituted bicycloalkylamine derivatives as modulators of chemokine receptor activity
US7288563B2 (en) 2004-02-19 2007-10-30 Bristol-Myers Squibb Company Substituted bicycloalkylamine derivatives as modulators of chemokine receptor activity
US7479496B2 (en) 2004-02-19 2009-01-20 Bristol-Myers Squibb Company Substituted spiro azabicyclics as modulators of chemokine receptor activity
GB0409236D0 (en) * 2004-04-26 2004-05-26 Novartis Ag Organic compounds
WO2006075004A2 (en) 2005-01-13 2006-07-20 Neurosearch A/S 3, 8 - substituted 8-aza-bicyclo[3.2.1] octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
ES2277745B1 (es) * 2005-06-14 2008-06-01 Laboratorios Almirall S.A. Derivados n-amida de 8-azabiciclo /3.2.1/oct-3-ilo como antagonistas de ccr1.
US20070105874A1 (en) * 2005-09-23 2007-05-10 Conforma Therapeutics Corporation Anti-Tumor Methods Using Multi Drug Resistance Independent Synthetic HSP90 Inhibitors
ITFI20120062A1 (it) * 2012-03-21 2013-09-22 Minerva Patents S A Componenti per il trattamento di malattie correlate a ischemia-riperfusione.
AU2014291711B2 (en) * 2013-07-18 2017-02-02 Novartis Ag Autotaxin inhibitors comprising a heteroaromatic ring-benzyl-amide-cycle core
CN104122392B (zh) * 2014-06-24 2016-05-25 上海交通大学医学院附属瑞金医院 检测ccl15趋化因子的试剂在制备筛选甲状腺滤泡癌试剂中的应用

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AR028947A1 (es) * 2000-06-20 2003-05-28 Astrazeneca Ab Compuestos novedosos
PA8575901A1 (es) * 2002-07-18 2004-07-20 Pfizer Prod Inc Derivados de piperidina novedosos

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AP2005003196A0 (en) 2005-03-31
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AU2003281527A1 (en) 2004-02-09
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ECSP055548A (es) 2005-03-10
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US20040063688A1 (en) 2004-04-01
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