IS6367A - Interferon-gamma tengiprótín - Google Patents
Interferon-gamma tengiprótínInfo
- Publication number
- IS6367A IS6367A IS6367A IS6367A IS6367A IS 6367 A IS6367 A IS 6367A IS 6367 A IS6367 A IS 6367A IS 6367 A IS6367 A IS 6367A IS 6367 A IS6367 A IS 6367A
- Authority
- IS
- Iceland
- Prior art keywords
- interferon
- coupling protein
- gamma coupling
- gamma
- protein
- Prior art date
Links
- 102000008070 Interferon-gamma Human genes 0.000 title 1
- 108010074328 Interferon-gamma Proteins 0.000 title 1
- 230000008878 coupling Effects 0.000 title 1
- 238000010168 coupling process Methods 0.000 title 1
- 238000005859 coupling reaction Methods 0.000 title 1
- 229960003130 interferon gamma Drugs 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/57—IFN-gamma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Pain & Pain Management (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Rheumatology (AREA)
- Biochemistry (AREA)
- Pulmonology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA199901631 | 1999-11-12 | ||
| US16629399P | 1999-11-18 | 1999-11-18 | |
| DKPA200000447 | 2000-03-17 | ||
| PCT/DK2000/000631 WO2001036001A2 (en) | 1999-11-12 | 2000-11-13 | Interferon gamma conjugates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IS6367A true IS6367A (is) | 2002-04-29 |
Family
ID=27221366
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IS6367A IS6367A (is) | 1999-11-12 | 2002-04-29 | Interferon-gamma tengiprótín |
Country Status (17)
| Country | Link |
|---|---|
| US (3) | US7232562B2 (is) |
| EP (1) | EP1231943A1 (is) |
| JP (1) | JP2003513681A (is) |
| KR (1) | KR20020065517A (is) |
| BG (1) | BG106790A (is) |
| BR (1) | BR0015506A (is) |
| CA (1) | CA2390292A1 (is) |
| CZ (1) | CZ20021836A3 (is) |
| HR (1) | HRP20020387A2 (is) |
| HU (1) | HUP0203409A3 (is) |
| IL (2) | IL149267A0 (is) |
| IS (1) | IS6367A (is) |
| MX (1) | MXPA02004671A (is) |
| NO (1) | NO20022251L (is) |
| PL (1) | PL356007A1 (is) |
| SK (1) | SK8292002A3 (is) |
| WO (1) | WO2001036001A2 (is) |
Families Citing this family (62)
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| US7959910B2 (en) | 2000-07-31 | 2011-06-14 | Biolex Therapeutics, Inc. | C-terminally truncated interferon alpha variants |
| US6958388B2 (en) | 2001-04-06 | 2005-10-25 | Maxygen, Aps | Interferon gamma polypeptide variants |
| US7038015B2 (en) | 2001-04-06 | 2006-05-02 | Maxygen Holdings, Ltd. | Interferon gamma polypeptide variants |
| US6964761B1 (en) | 2001-12-12 | 2005-11-15 | New York University | Method of treating idiopathic pulmonary fibrosis with aerosolized IFN-γ |
| US20060270618A1 (en) * | 2001-12-18 | 2006-11-30 | Dorian Bevec | Novel pharmaceutical composition of interferon gamma or pirfenidone with molecular diagnostics for the improved treatment of interstitial lung diseases |
| PT2298278E (pt) | 2002-06-07 | 2016-02-25 | Dyax Corp | Prevenção e redução da perda de sangue e resposta inflamatória |
| US7153829B2 (en) | 2002-06-07 | 2006-12-26 | Dyax Corp. | Kallikrein-inhibitor therapies |
| WO2004005341A2 (en) * | 2002-07-03 | 2004-01-15 | Maxygen Holdings Ltd. | Full-length interferon gamma polypeptide variants |
| WO2004019758A2 (en) * | 2002-08-27 | 2004-03-11 | Intermune, Inc. | Methods of treating idiopathic pulmonary fibrosis |
| WO2004022593A2 (en) * | 2002-09-09 | 2004-03-18 | Nautilus Biotech | Rational evolution of cytokines for higher stability, the cytokines and encoding nucleic acid molecules |
| US9453251B2 (en) | 2002-10-08 | 2016-09-27 | Pfenex Inc. | Expression of mammalian proteins in Pseudomonas fluorescens |
| WO2004099245A1 (de) * | 2003-05-05 | 2004-11-18 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Stabilisiertes interferon-ϝ |
| CA2525647A1 (en) | 2003-05-16 | 2005-02-24 | Intermune, Inc. | Synthetic chemokine receptor ligands and methods of use thereof |
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| US7597884B2 (en) | 2004-08-09 | 2009-10-06 | Alios Biopharma, Inc. | Hyperglycosylated polypeptide variants and methods of use |
| US7235530B2 (en) | 2004-09-27 | 2007-06-26 | Dyax Corporation | Kallikrein inhibitors and anti-thrombolytic agents and uses thereof |
| BRPI0618947B1 (pt) | 2005-11-23 | 2022-07-19 | Acceleron Pharma Inc | Polipeptídeo actriia que se liga à ativina, polinucleotídeo isolado, polinucleotídeo recombinante, métodopara preparar um polipeptídeo actriia que se liga à ativina, preparação farmacêutica e uso de uma proteína de fusão actriia-fc para promover o crescimento ósseo e inibir a ressorção óssea |
| US8128933B2 (en) | 2005-11-23 | 2012-03-06 | Acceleron Pharma, Inc. | Method of promoting bone growth by an anti-activin B antibody |
| US8895016B2 (en) | 2006-12-18 | 2014-11-25 | Acceleron Pharma, Inc. | Antagonists of activin-actriia and uses for increasing red blood cell levels |
| TWI584815B (zh) | 2007-02-01 | 2017-06-01 | 艾瑟勒朗法瑪公司 | 活化素-ＡｃｔＲＩＩａ拮抗劑及其治療或預防乳癌之用途 |
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| US9580719B2 (en) | 2007-04-27 | 2017-02-28 | Pfenex, Inc. | Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins |
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| CL2008002399A1 (es) * | 2007-08-16 | 2009-01-02 | Pharmaessentia Corp | Conjugado sustancialmente puro que posee una porcion polimerica, una porcion proteica (interferon alfa 2b) y un ligante alifatico de 1 a 10 atomos de carbono, util en el tratamiento de las hepatitis b o c. |
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| US8216997B2 (en) | 2008-08-14 | 2012-07-10 | Acceleron Pharma, Inc. | Methods for increasing red blood cell levels and treating anemia using a combination of GDF traps and erythropoietin receptor activators |
| DK3750552T5 (da) | 2008-08-14 | 2024-08-26 | Acceleron Pharma Inc | Gdf-fælder |
| JP2013516389A (ja) | 2009-01-06 | 2013-05-13 | ダイアックス コーポレーション | カリクレイン阻害剤による粘膜炎治療 |
| MX355042B (es) | 2009-06-08 | 2018-04-02 | Acceleon Pharma Inc | Metodos para aumentar adipositos termogenicos. |
| CN107267520A (zh) | 2009-06-12 | 2017-10-20 | 阿塞勒隆制药公司 | 截短的actriib‑fc融合蛋白 |
| ES2658292T3 (es) | 2009-11-17 | 2018-03-09 | Acceleron Pharma, Inc. | Proteínas ActRIIB y variantes y usos de las mismas con respecto a la inducción de la utrofina para el tratamiento de la distrofia muscular |
| ES2905545T3 (es) | 2010-01-06 | 2022-04-11 | Takeda Pharmaceuticals Co | Proteínas de unión a calicreína plasmática |
| CA2817008A1 (en) | 2010-11-08 | 2012-05-18 | Acceleron Pharma Inc. | Actriia binding agents and uses thereof |
| KR102011156B1 (ko) | 2011-01-06 | 2019-08-16 | 다이액스 코포레이션 | 혈장 칼리크레인 결합 단백질 |
| RU2678117C2 (ru) | 2012-11-02 | 2019-01-23 | Селджин Корпорейшн | Антагонисты активина-actrii и их применение для лечения нарушений костной ткани и других нарушений |
| CN105658233B (zh) | 2013-10-04 | 2020-09-04 | 安吉尼科分子传输公司 | 使用携带药物的、双特异性配体靶向的微细胞和干扰素-γ的联合肿瘤治疗 |
| IL247942B (en) | 2014-03-27 | 2022-09-01 | Dyax Corp | Compositions and methods for drops in macular edema as a result of diabetes |
| CN114699529A (zh) | 2014-06-13 | 2022-07-05 | 阿塞勒隆制药公司 | 用于治疗溃疡的方法和组合物 |
| MA41052A (fr) | 2014-10-09 | 2017-08-15 | Celgene Corp | Traitement d'une maladie cardiovasculaire à l'aide de pièges de ligands d'actrii |
| AU2015342908B2 (en) | 2014-11-06 | 2021-06-24 | Pharmaessentia Corporation | Dosage regimen for pegylated interferon |
| EP3227675B1 (en) | 2014-12-03 | 2023-03-15 | Celgene Corporation | Activin-actrii antagonists and uses for treating myelodysplastic syndrome |
| US20160346382A1 (en) * | 2015-05-27 | 2016-12-01 | Northwestern University | Carbohydrate-modified particles and particulate formulations for modulating an immune response |
| US11286307B2 (en) | 2015-12-11 | 2022-03-29 | Takeda Pharmaceutical Company Limited | Plasma kallikrein inhibitors and uses thereof for treating hereditary angioedema attack |
| CN110114368B (zh) * | 2016-10-24 | 2024-08-02 | 奥睿尼斯生物科学私人有限公司 | 靶向突变干扰素-γ及其用途 |
| US12410226B2 (en) | 2018-07-30 | 2025-09-09 | The Board Of Trustees Of The Leland Stanford Junior University | Interferon-gamma biased agonists |
| US20220000921A1 (en) * | 2018-11-20 | 2022-01-06 | Innovative Cellular Therapeutics Holdings, Ltd. | Modified Cell Expressing Therapeutic Agent and Uses thereof |
| US12702708B2 (en) | 2019-08-21 | 2026-08-11 | Innovative Cellular Therapeutics Holdings, Ltd. | Presenting cell and use thereof in cell therapy |
| AU2021209045A1 (en) | 2020-01-13 | 2022-07-28 | Takeda Pharmaceutical Company Limited | Plasma kallikrein inhibitors and uses thereof for treating pediatric hereditary angioedema attack |
| US20250270273A1 (en) * | 2021-07-12 | 2025-08-28 | Nektar Therapeutics | Polymer engineered forms of interferon-gamma and methods of use |
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| US5770191A (en) | 1995-05-24 | 1998-06-23 | University Of Florida | Active C-terminal peptides of interferon--gamma and their use |
| DE19535853C2 (de) | 1995-09-18 | 1999-04-01 | Fraunhofer Ges Forschung | Varianten des rekombinanten humanen Interferon-gamma, Verfahren zu ihrer Herstellung und ihre Verwendung |
| EP0795332B1 (en) | 1996-03-14 | 2005-06-01 | Mondobiotech Interferon SA | Medical use of gamma-interferon in interstitial lung diseases |
| ATE375363T1 (de) * | 1997-07-14 | 2007-10-15 | Bolder Biotechnology Inc | Derivate des wachstumshormons und verwandte proteine |
| US6451986B1 (en) * | 1998-06-22 | 2002-09-17 | Immunex Corporation | Site specific protein modification |
| JP2003510295A (ja) | 1999-09-28 | 2003-03-18 | アマリロ バイオサイエンシズ，インコーポレイテッド | 疾患の治療のための低投与量のｉｆｎガンマ |
| JP2003513681A (ja) | 1999-11-12 | 2003-04-15 | マキシゲン・ホールディングス・リミテッド | インターフェロンガンマ・コンジュゲート |
-
2000
- 2000-11-13 JP JP2001537991A patent/JP2003513681A/ja active Pending
- 2000-11-13 SK SK829-2002A patent/SK8292002A3/sk unknown
- 2000-11-13 BR BR0015506-3A patent/BR0015506A/pt not_active IP Right Cessation
- 2000-11-13 KR KR1020027006113A patent/KR20020065517A/ko not_active Ceased
- 2000-11-13 PL PL00356007A patent/PL356007A1/xx unknown
- 2000-11-13 WO PCT/DK2000/000631 patent/WO2001036001A2/en not_active Ceased
- 2000-11-13 HR HR20020387A patent/HRP20020387A2/hr not_active Application Discontinuation
- 2000-11-13 EP EP00974356A patent/EP1231943A1/en not_active Withdrawn
- 2000-11-13 CA CA002390292A patent/CA2390292A1/en not_active Abandoned
- 2000-11-13 HU HU0203409A patent/HUP0203409A3/hu unknown
- 2000-11-13 CZ CZ20021836A patent/CZ20021836A3/cs unknown
- 2000-11-13 IL IL14926700A patent/IL149267A0/xx unknown
- 2000-11-13 MX MXPA02004671A patent/MXPA02004671A/es active IP Right Grant
-
2002
- 2002-04-22 IL IL149267A patent/IL149267A/en not_active IP Right Cessation
- 2002-04-29 IS IS6367A patent/IS6367A/is unknown
- 2002-05-10 NO NO20022251A patent/NO20022251L/no not_active Application Discontinuation
- 2002-06-07 BG BG106790A patent/BG106790A/bg unknown
-
2003
- 2003-02-19 US US10/369,495 patent/US7232562B2/en not_active Expired - Fee Related
-
2006
- 2006-03-16 US US11/377,252 patent/US7504237B2/en not_active Expired - Fee Related
-
2007
- 2007-02-01 US US11/701,107 patent/US20080176323A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20030153046A1 (en) | 2003-08-14 |
| CA2390292A1 (en) | 2001-05-25 |
| HRP20020387A2 (en) | 2005-10-31 |
| NO20022251L (no) | 2002-07-05 |
| BG106790A (bg) | 2003-04-30 |
| PL356007A1 (en) | 2004-05-31 |
| KR20020065517A (ko) | 2002-08-13 |
| CZ20021836A3 (cs) | 2002-08-14 |
| IL149267A (en) | 2008-07-08 |
| US7232562B2 (en) | 2007-06-19 |
| NO20022251D0 (no) | 2002-05-10 |
| EP1231943A1 (en) | 2002-08-21 |
| US7504237B2 (en) | 2009-03-17 |
| IL149267A0 (en) | 2002-11-10 |
| SK8292002A3 (en) | 2002-12-03 |
| BR0015506A (pt) | 2002-07-23 |
| WO2001036001A3 (en) | 2001-11-15 |
| US20060194951A1 (en) | 2006-08-31 |
| HUP0203409A2 (hu) | 2003-01-28 |
| MXPA02004671A (es) | 2004-09-10 |
| HUP0203409A3 (en) | 2005-06-28 |
| WO2001036001A2 (en) | 2001-05-25 |
| JP2003513681A (ja) | 2003-04-15 |
| US20080176323A1 (en) | 2008-07-24 |
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