IS2419B - Glýsín-setin þíeno[2,3-d]pýrimidín með sameinaða LH og FSH gerandefnisvirkni - Google Patents

Glýsín-setin þíeno[2,3-d]pýrimidín með sameinaða LH og FSH gerandefnisvirkni

Info

Publication number
IS2419B
IS2419B IS7152A IS7152A IS2419B IS 2419 B IS2419 B IS 2419B IS 7152 A IS7152 A IS 7152A IS 7152 A IS7152 A IS 7152A IS 2419 B IS2419 B IS 2419B
Authority
IS
Iceland
Prior art keywords
sup
alkyl
hydroxy
glycine
pyrimidine
Prior art date
Application number
IS7152A
Other languages
English (en)
Other versions
IS7152A (is
Inventor
Gerard Jules Marie Hanssen Robert
Marius Timmers Cornelis
Kelder Jan
Original Assignee
N.V. Organon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by N.V. Organon filed Critical N.V. Organon
Publication of IS7152A publication Critical patent/IS7152A/is
Publication of IS2419B publication Critical patent/IS2419B/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A61P5/08—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH for decreasing, blocking or antagonising the activity of the anterior pituitary hormones

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IS7152A 2001-09-04 2004-02-13 Glýsín-setin þíeno[2,3-d]pýrimidín með sameinaða LH og FSH gerandefnisvirkni IS2419B (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01203328 2001-09-04
PCT/EP2002/009648 WO2003020727A1 (en) 2001-09-04 2002-08-29 GLYCINE-SUBSTITUTED THIENO [2,3-d]PYRIMIDINES WITH COMBINED LH AND FSH AGONISTIC ACTIVITY

Publications (2)

Publication Number Publication Date
IS7152A IS7152A (is) 2004-02-13
IS2419B true IS2419B (is) 2008-10-15

Family

ID=8180877

Family Applications (1)

Application Number Title Priority Date Filing Date
IS7152A IS2419B (is) 2001-09-04 2004-02-13 Glýsín-setin þíeno[2,3-d]pýrimidín með sameinaða LH og FSH gerandefnisvirkni

Country Status (27)

Country Link
US (1) US7375109B2 (is)
EP (1) EP1427734B1 (is)
JP (1) JP4263094B2 (is)
KR (1) KR100891630B1 (is)
CN (1) CN1261437C (is)
AR (1) AR036408A1 (is)
AT (1) ATE309251T1 (is)
AU (1) AU2002333750B2 (is)
BR (1) BR0212173A (is)
CA (1) CA2457212C (is)
CY (1) CY1106052T1 (is)
DE (1) DE60207280T2 (is)
DK (1) DK1427734T3 (is)
EC (1) ECSP044990A (is)
ES (1) ES2252540T3 (is)
HR (1) HRP20040194A2 (is)
HU (1) HUP0401443A3 (is)
IL (2) IL160194A0 (is)
IS (1) IS2419B (is)
MX (1) MXPA04002046A (is)
NO (1) NO328792B1 (is)
NZ (1) NZ531375A (is)
PE (1) PE20030467A1 (is)
PL (1) PL368388A1 (is)
RU (1) RU2294331C2 (is)
WO (1) WO2003020727A1 (is)
ZA (1) ZA200401459B (is)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6890923B2 (en) * 2002-12-16 2005-05-10 Astrazeneca Ab Compounds
KR100666484B1 (ko) * 2005-02-04 2007-01-09 삼성전자주식회사 반도체 메모리 장치의 입출력 회로 및 입출력 방법
JP5718233B2 (ja) 2008-10-20 2015-05-13 ザ ガバメント オブ ザ ユナイテッド ステイツ オブ アメリカ アズ リプレゼンテッド バイ ザ セクレタリー オブ ザ デパートメント オブ ヘルス アンド ヒューマン サービシーズ 甲状腺刺激ホルモン受容体（ｔｓｈｒ）の低分子量アゴニスト
CN101762915B (zh) * 2008-12-24 2013-04-17 北京京东方光电科技有限公司 Tft-lcd阵列基板及其驱动方法
EP2563777A4 (en) 2010-04-08 2013-09-04 Us Health INVERSE AGONISTS AND NEUTRAL AGONISTS FOR THE TSH RECEPTOR
SI3415517T1 (sl) * 2012-09-28 2022-06-30 Takeda Pharmaceutical Company Limited Kristalna oblika 1-(4-1-(2,6-difluorobenzil)-5-dimetilaminometil-3-(6- metoksipiridazin-3-il)-2,4-diokso-1,2,3,4-tetrahidrotieno(2,3-D)- pirimidin-6il)fenil)-3-metoksiurea

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE86484T1 (de) 1987-08-08 1993-03-15 Akzo Nv Kontrazeptives implantat.
TW564247B (en) * 1999-04-08 2003-12-01 Akzo Nobel Nv Bicyclic heteraromatic compound

Also Published As

Publication number Publication date
ATE309251T1 (de) 2005-11-15
CY1106052T1 (el) 2011-04-06
ECSP044990A (es) 2004-04-28
KR100891630B1 (ko) 2009-04-03
WO2003020727A1 (en) 2003-03-13
BR0212173A (pt) 2004-07-20
US7375109B2 (en) 2008-05-20
CN1261437C (zh) 2006-06-28
IS7152A (is) 2004-02-13
PL368388A1 (en) 2005-03-21
MXPA04002046A (es) 2004-07-16
HRP20040194A2 (en) 2004-08-31
NO328792B1 (no) 2010-05-18
ZA200401459B (en) 2004-11-22
US20040180907A1 (en) 2004-09-16
AU2002333750B2 (en) 2008-02-21
CA2457212A1 (en) 2003-03-13
RU2004110036A (ru) 2005-10-10
NZ531375A (en) 2005-06-24
AR036408A1 (es) 2004-09-08
HUP0401443A3 (en) 2008-05-28
JP4263094B2 (ja) 2009-05-13
CA2457212C (en) 2011-02-15
DE60207280D1 (de) 2005-12-15
IL160194A (en) 2009-06-15
CN1551883A (zh) 2004-12-01
HUP0401443A2 (hu) 2004-11-29
EP1427734A1 (en) 2004-06-16
KR20040029135A (ko) 2004-04-03
NO20040922L (no) 2004-03-03
JP2005504784A (ja) 2005-02-17
PE20030467A1 (es) 2003-05-26
EP1427734B1 (en) 2005-11-09
IL160194A0 (en) 2004-07-25
ES2252540T3 (es) 2006-05-16
RU2294331C2 (ru) 2007-02-27
DK1427734T3 (da) 2006-03-06
DE60207280T2 (de) 2006-05-18

Similar Documents

Publication Publication Date Title
BG103785A (en) Pyrrolo[2,3-d]pyrimidines and their application as tyrosine kinase inhibitors
MXPA06000716A (es) Derivados de quinolina y quinazolina que tienen afinidad hacia receptores del tipo 5ht1.
WO2003106428A8 (fr) Derives d'arylsulfonamides et leur utilisation en tant que antagonistes au recepteur b1 de la bradykinine
CA2455181A1 (en) Benzimidazo[4,5-f]isoquinolinone derivatives
MY130622A (en) Naphthyridine derivatives, their preparation and their use as phosphodiesterase isoenzyme 4 (pde4) inhibitors
BG104248A (en) Benzamidoxim derivatives, intermediate products and methods for preparing and using them as fungicides
CA2037630A1 (en) Nitrogen-containing heterocylic compounds, their production and use
DK1442019T3 (da) Amidderivater som glycogensynthasekinase 3- beta-inhibitorer
TW359670B (en) Process for producing quinazolin-4-one derivatives
YU55603A (sh) Derivati purina kao antagonisti purinergiskog receptora
HUP0203645A2 (hu) Fenilpiperazinil-származékok, ezeket tartalmazó gyógyszerkészítmények és alkalmazásuk
RU2009105823A (ru) Производные пиримидина и их применение в качестве пестицидов
AU2413995A (en) Bicyclic amidine derivatives as inhibitors of nitric oxide synthetase
IS7152A (is) Glýsín-setin þíeno[2,3-d]pýrimidín með sameinaða LH og FSH gerandefnisvirkni
CA2302943A1 (en) Phthalazine compounds and therapeutic agents for erectile dysfunction
IS7130A (is) Þénó[2,3-d]pýrimidín með sameinaðri LH og FSH gerandefnisvirkni
MXPA04003278A (es) Derivados de 5-metoxi-8-aril-?1,2,4?triazolo?1,5-a?piridina como antagonistas del receptor de adenosina.
DE60016786D1 (de) Bicyclische vasopressin-agoniste
MY130750A (en) Pyrimidine derivatives useful as selective cox-2 inhibitors
MXPA04002838A (es) Derivados de alquilaminopiridazinona sustituidos, procedimiento para la preparacion de los mismos y composiciones farmaceuticas que los contienen.
IL150276A0 (en) Indole derivatives as mcp-1 receptor antagonists
GB0106419D0 (en) Novel compounds
TW200504054A (en) Heteroarylsulfonanilide derivative and pharmaceutical composition containing the same
CA2206104A1 (en) Adamantyl substituted oxindoles as pharmaceuticals agents
TH82131B (th) ไธอีโน[2,3-ดี]พัยริมิดีนที่มีฤทธิ์แอโกนิสท์ของ lh และ fsh รวมกัน