IS7130A - Þénó[2,3-d]pýrimidín með sameinaðri LH og FSH gerandefnisvirkni - Google Patents

Þénó[2,3-d]pýrimidín með sameinaðri LH og FSH gerandefnisvirkni

Info

Publication number
IS7130A
IS7130A IS7130A IS7130A IS7130A IS 7130 A IS7130 A IS 7130A IS 7130 A IS7130 A IS 7130A IS 7130 A IS7130 A IS 7130A IS 7130 A IS7130 A IS 7130A
Authority
IS
Iceland
Prior art keywords
pyrimidine
theno
combined
agonist activity
fsh agonist
Prior art date
Application number
IS7130A
Other languages
English (en)
Other versions
IS2424B (is
Inventor
Gerard Jules Marie Hanssen Robert
Marius Timmers Cornelis
Original Assignee
Akzo Nobel N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel N.V. filed Critical Akzo Nobel N.V.
Publication of IS7130A publication Critical patent/IS7130A/is
Publication of IS2424B publication Critical patent/IS2424B/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A61P5/08—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH for decreasing, blocking or antagonising the activity of the anterior pituitary hormones

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IS7130A 2001-09-04 2004-01-29 Þíenó[2,3-d]pýrimidín með sameinaðri LH og FSH gerandefnisvirkni IS2424B (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01203327 2001-09-04
PCT/EP2002/009647 WO2003020726A1 (en) 2001-09-04 2002-08-29 Thieno[2,3-d]pyrimidines with combined lh and fsh agonistic activity

Publications (2)

Publication Number Publication Date
IS7130A true IS7130A (is) 2004-01-29
IS2424B IS2424B (is) 2008-10-15

Family

ID=8180876

Family Applications (1)

Application Number Title Priority Date Filing Date
IS7130A IS2424B (is) 2001-09-04 2004-01-29 Þíenó[2,3-d]pýrimidín með sameinaðri LH og FSH gerandefnisvirkni

Country Status (28)

Country Link
US (1) US7317006B2 (is)
EP (1) EP1427733B1 (is)
JP (1) JP4262092B2 (is)
KR (1) KR100900018B1 (is)
CN (1) CN1246324C (is)
AR (1) AR036407A1 (is)
AT (1) ATE345345T1 (is)
AU (1) AU2002337035B2 (is)
BR (1) BR0211938A (is)
CA (1) CA2456901C (is)
CY (1) CY1106012T1 (is)
DE (1) DE60216128T2 (is)
DK (1) DK1427733T3 (is)
ES (1) ES2275005T3 (is)
HR (1) HRP20040202A2 (is)
HU (1) HUP0401444A3 (is)
IL (1) IL160084A0 (is)
IS (1) IS2424B (is)
MX (1) MXPA04002045A (is)
NO (1) NO20040927L (is)
NZ (1) NZ531340A (is)
PE (1) PE20030439A1 (is)
PL (1) PL368502A1 (is)
PT (1) PT1427733E (is)
RU (1) RU2298011C2 (is)
TW (1) TWI228508B (is)
WO (1) WO2003020726A1 (is)
ZA (1) ZA200401455B (is)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6890923B2 (en) * 2002-12-16 2005-05-10 Astrazeneca Ab Compounds
GB0315950D0 (en) * 2003-06-11 2003-08-13 Xention Discovery Ltd Compounds
GB0525164D0 (en) * 2005-12-09 2006-01-18 Xention Discovery Ltd Compounds
CN100430403C (zh) * 2006-10-13 2008-11-05 中国科学院上海有机化学研究所 3-芳基-5,6-取代噻吩并嘧啶-4-羰基-2-巯基乙腈、合成方法和用途
US20090118276A1 (en) * 2007-11-02 2009-05-07 Wyeth Thienopyrimidines, thienopyridines, and pyrrolopyrimidines as b-raf inhibitors
TWI389913B (zh) * 2008-09-08 2013-03-21 Lg Life Sciences Ltd 并合雜環化合物
JP5718233B2 (ja) 2008-10-20 2015-05-13 ザ ガバメント オブ ザ ユナイテッド ステイツ オブ アメリカ アズ リプレゼンテッド バイ ザ セクレタリー オブ ザ デパートメント オブ ヘルス アンド ヒューマン サービシーズ 甲状腺刺激ホルモン受容体（ｔｓｈｒ）の低分子量アゴニスト
GB0905525D0 (en) 2009-03-31 2009-05-13 Univ Leiden Compounds and uses
CN102811617A (zh) 2010-01-22 2012-12-05 拜耳知识产权有限责任公司 杀螨和/或杀虫活性物质结合物
EP2563777A4 (en) 2010-04-08 2013-09-04 Us Health INVERSE AGONISTS AND NEUTRAL AGONISTS FOR THE TSH RECEPTOR
RU2619091C2 (ru) * 2015-10-13 2017-05-11 Министерство Промышленности И Торговли Рф Цилиндрический термоэмиссионный катод
WO2023239854A2 (en) * 2022-06-08 2023-12-14 Icahn School Of Medicine At Mount Sinai Method of treating obesity with a luteinizing hormone receptor agonist

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE86484T1 (de) 1987-08-08 1993-03-15 Akzo Nv Kontrazeptives implantat.
TW564247B (en) 1999-04-08 2003-12-01 Akzo Nobel Nv Bicyclic heteraromatic compound

Also Published As

Publication number Publication date
WO2003020726A1 (en) 2003-03-13
HUP0401444A3 (en) 2008-05-28
ATE345345T1 (de) 2006-12-15
US20040180873A1 (en) 2004-09-16
EP1427733B1 (en) 2006-11-15
DE60216128D1 (de) 2006-12-28
PL368502A1 (en) 2005-04-04
JP2005505555A (ja) 2005-02-24
KR100900018B1 (ko) 2009-06-01
IS2424B (is) 2008-10-15
PT1427733E (pt) 2007-02-28
DK1427733T3 (da) 2007-03-19
AR036407A1 (es) 2004-09-08
CN1246324C (zh) 2006-03-22
MXPA04002045A (es) 2004-07-08
HUP0401444A2 (hu) 2004-11-29
RU2298011C2 (ru) 2007-04-27
CY1106012T1 (el) 2011-04-06
CA2456901C (en) 2011-01-04
US7317006B2 (en) 2008-01-08
KR20040029134A (ko) 2004-04-03
DE60216128T2 (de) 2007-09-27
TWI228508B (en) 2005-03-01
HRP20040202A2 (en) 2004-08-31
IL160084A0 (en) 2004-06-20
JP4262092B2 (ja) 2009-05-13
CA2456901A1 (en) 2003-03-13
PE20030439A1 (es) 2003-05-17
ZA200401455B (en) 2004-11-19
EP1427733A1 (en) 2004-06-16
NZ531340A (en) 2005-08-26
AU2002337035B2 (en) 2008-04-24
BR0211938A (pt) 2004-09-21
RU2004110042A (ru) 2005-08-20
NO20040927L (no) 2004-03-03
CN1551884A (zh) 2004-12-01
ES2275005T3 (es) 2007-06-01

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TH82131B (th) ไธอีโน[2,3-ดี]พัยริมิดีนที่มีฤทธิ์แอโกนิสท์ของ lh และ fsh รวมกัน