IN2015DN00202A - - Google Patents
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- Publication number
- IN2015DN00202A IN2015DN00202A IN202DEN2015A IN2015DN00202A IN 2015DN00202 A IN2015DN00202 A IN 2015DN00202A IN 202DEN2015 A IN202DEN2015 A IN 202DEN2015A IN 2015DN00202 A IN2015DN00202 A IN 2015DN00202A
- Authority
- IN
- India
- Prior art keywords
- mula
- inhibitors
- compounds
- formula
- neutrophil elastase
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP12176079 | 2012-07-12 | ||
EP13158756 | 2013-03-12 | ||
PCT/EP2013/064603 WO2014009425A1 (fr) | 2012-07-12 | 2013-07-10 | Inhibition d'enzymes |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2015DN00202A true IN2015DN00202A (fr) | 2015-06-12 |
Family
ID=48953361
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN202DEN2015 IN2015DN00202A (fr) | 2012-07-12 | 2013-07-10 |
Country Status (11)
Country | Link |
---|---|
US (1) | US9199984B2 (fr) |
EP (1) | EP2872509B1 (fr) |
KR (1) | KR20150031318A (fr) |
CN (1) | CN104428300B (fr) |
AR (1) | AR091737A1 (fr) |
BR (1) | BR112015000507A2 (fr) |
CA (1) | CA2878792A1 (fr) |
HK (1) | HK1207078A1 (fr) |
IN (1) | IN2015DN00202A (fr) |
RU (1) | RU2638537C2 (fr) |
WO (1) | WO2014009425A1 (fr) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105873933A (zh) | 2013-12-16 | 2016-08-17 | 奇斯药制品公司 | 作为人中性白细胞弹性蛋白酶抑制剂的四氢三唑并嘧啶衍生物 |
US9487528B2 (en) | 2014-06-09 | 2016-11-08 | Chiesi Farmaceutici S.P.A. | Compounds |
US9657015B2 (en) | 2014-07-31 | 2017-05-23 | Boehringer Ingelheim International Gmbh | Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity |
US9475779B2 (en) | 2014-07-31 | 2016-10-25 | Boehringer Ingelheim International Gmbh | Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity |
US9440930B2 (en) | 2014-07-31 | 2016-09-13 | Boehringer Ingelheim International Gmbh | Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity |
US9409870B2 (en) | 2014-12-15 | 2016-08-09 | Chiesi Farmaceutici S.P.A. | Compounds |
CN109311850B (zh) | 2016-05-31 | 2021-11-19 | 奇斯药制品公司 | 作为人嗜中性粒细胞弹性蛋白酶抑制剂的咪唑酮化合物 |
AR108608A1 (es) | 2016-05-31 | 2018-09-05 | Chiesi Farm Spa | Derivados de pirazolil carbonilo inhibidores de ahr |
WO2017207433A1 (fr) * | 2016-05-31 | 2017-12-07 | Chiesi Farmaceutici S.P.A. | Composés hétérocycliques destinés à être utilisés dans le traitement d'une maladie dans laquelle est impliquée l'élastase neutrophile humaine (hne) |
AU2018223313B2 (en) | 2017-02-27 | 2023-02-23 | Géza BÁLINT | Smart device with a display that enables simultaneous multi-functional handling of the displayed information and/or data |
TW202118391A (zh) | 2019-07-23 | 2021-05-16 | 德商拜耳廠股份有限公司 | 作為殺蟲劑之新穎雜芳基三唑化合物(二) |
TW202118754A (zh) | 2019-07-23 | 2021-05-16 | 德商拜耳廠股份有限公司 | 作為殺蟲劑之新穎雜芳基三唑化合物(一) |
JP2023500182A (ja) | 2019-09-17 | 2023-01-05 | メレオ バイオファーマ 4 リミテッド | 移植片拒絶反応、閉塞性細気管支炎症候群、及び移植片対宿主病の治療に使用するためのアルベレスタット |
MX2022004366A (es) | 2019-10-09 | 2022-05-06 | Bayer Ag | Nuevos compuestos de heteroarilo-triazol como pesticidas. |
UY38911A (es) | 2019-10-09 | 2021-05-31 | Bayer Ag | Compuestos de heteroarilo-triazol como pesticidas, formulaciones, usos y métodos de uso de los mismos |
US20230117470A1 (en) * | 2019-11-01 | 2023-04-20 | Bristol-Myers Squibb Company | Substituted pyrazole compounds as toll receptor inhibitors |
TW202134226A (zh) | 2019-11-18 | 2021-09-16 | 德商拜耳廠股份有限公司 | 作為殺蟲劑之新穎雜芳基-三唑化合物 |
FI4106757T3 (fi) | 2020-04-16 | 2023-10-23 | Mereo Biopharma 4 Ltd | Neutrofiilien elastaasin inhibiittori alvelestaattia sisältäviä menetelmiä alfa-1-antitrypsiinipuutoksen välittämän hengityselintaudin hoitamiseksi |
CN113480486B (zh) * | 2021-07-30 | 2022-05-24 | 赣南师范大学 | 一种3-胺基-1,2,4-三唑类衍生物及其制备方法和应用 |
CA3234399A1 (fr) | 2021-10-20 | 2023-04-27 | Mereo Biopharma 4 Limited | Inhibiteurs de l'elastase neutrophile utilises dans le traitement de la fibrose |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4259504A (en) | 1979-08-27 | 1981-03-31 | American Cyanamid Company | Substituted 1H-1,2,4-triazoles |
US4451471A (en) | 1981-03-18 | 1984-05-29 | Ciba-Geigy Corporation | Certain 2,4,5-tri-substituted thiazoles, pharmaceutical compositions containing same and methods of using same |
US4576958A (en) | 1984-01-23 | 1986-03-18 | E. I. Du Pont De Nemours And Company | Antihypertensive 4,5-diaryl-1H-imidazole-2-methanol derivatives |
AU650953B2 (en) | 1991-03-21 | 1994-07-07 | Novartis Ag | Inhaler |
ES2184633B1 (es) | 2001-08-07 | 2004-08-01 | J. URIACH & CIA, S.A. | Procedimiento para la preparacion de derivados de 4-(imidazol-1-il) bencenosulfonamida. |
US6693116B2 (en) * | 2001-10-08 | 2004-02-17 | Hoffmann-La Roche Inc. | Adenosine receptor ligands |
US7524860B2 (en) | 2004-10-07 | 2009-04-28 | Pfizer Inc. | Antibacterial agents |
US7902374B2 (en) | 2005-05-06 | 2011-03-08 | Universal Display Corporation | Stability OLED materials and devices |
US20080125587A1 (en) | 2006-05-25 | 2008-05-29 | Chimmanamada Dinesh U | Synthesis of triazole compounds that modulate HSP90 activity |
WO2009061271A1 (fr) * | 2007-11-06 | 2009-05-14 | Astrazeneca Ab | Certains dérivés de 2-pyrazinone et leur utilisation comme inhibiteurs d'élastase des neutrophiles |
PE20091953A1 (es) | 2008-05-08 | 2010-01-09 | Du Pont | Azoles sustituidos como fungicidas |
US8338604B2 (en) * | 2008-06-20 | 2012-12-25 | Bristol-Myers Squibb Company | Imidazopyridine and imidazopyrazine compounds useful as kinase inhibitors |
CN102131806A (zh) * | 2008-06-20 | 2011-07-20 | 百时美施贵宝公司 | 用作激酶抑制剂的三唑并吡啶化合物 |
DE102009004197A1 (de) * | 2009-01-09 | 2010-07-15 | Bayer Schering Pharma Aktiengesellschaft | Heterocyclisch anellierte Diaryldihydropyrimidin-Derivate und ihre Verwendung |
CA2773618A1 (fr) * | 2009-10-02 | 2011-04-07 | Astrazeneca Ab | Composes 2-pyridones utilises comme inhibiteurs d'elastase de neutrophile |
-
2013
- 2013-07-10 IN IN202DEN2015 patent/IN2015DN00202A/en unknown
- 2013-07-10 CA CA2878792A patent/CA2878792A1/fr not_active Abandoned
- 2013-07-10 KR KR20157002129A patent/KR20150031318A/ko not_active Application Discontinuation
- 2013-07-10 BR BR112015000507A patent/BR112015000507A2/pt not_active IP Right Cessation
- 2013-07-10 CN CN201380036973.4A patent/CN104428300B/zh not_active Expired - Fee Related
- 2013-07-10 EP EP13747801.2A patent/EP2872509B1/fr active Active
- 2013-07-10 WO PCT/EP2013/064603 patent/WO2014009425A1/fr active Application Filing
- 2013-07-10 RU RU2015104644A patent/RU2638537C2/ru not_active IP Right Cessation
- 2013-07-11 AR ARP130102470 patent/AR091737A1/es unknown
- 2013-07-12 US US13/940,555 patent/US9199984B2/en not_active Expired - Fee Related
-
2015
- 2015-08-11 HK HK15107783.9A patent/HK1207078A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP2872509A1 (fr) | 2015-05-20 |
CN104428300B (zh) | 2016-11-09 |
RU2015104644A (ru) | 2016-08-27 |
BR112015000507A2 (pt) | 2017-06-27 |
CN104428300A (zh) | 2015-03-18 |
HK1207078A1 (en) | 2016-01-22 |
WO2014009425A1 (fr) | 2014-01-16 |
US9199984B2 (en) | 2015-12-01 |
EP2872509B1 (fr) | 2016-09-14 |
RU2638537C2 (ru) | 2017-12-14 |
KR20150031318A (ko) | 2015-03-23 |
CA2878792A1 (fr) | 2014-01-16 |
US20140018345A1 (en) | 2014-01-16 |
AR091737A1 (es) | 2015-02-25 |
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