IN2014MN02513A - - Google Patents
Info
- Publication number
- IN2014MN02513A IN2014MN02513A IN2513MUN2014A IN2014MN02513A IN 2014MN02513 A IN2014MN02513 A IN 2014MN02513A IN 2513MUN2014 A IN2513MUN2014 A IN 2513MUN2014A IN 2014MN02513 A IN2014MN02513 A IN 2014MN02513A
- Authority
- IN
- India
- Prior art keywords
- subunits
- mcm
- hmcm6
- hmcm2
- inhibiting
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2458/00—Labels used in chemical analysis of biological material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/10—Screening for compounds of potential therapeutic value involving cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261644442P | 2012-05-09 | 2012-05-09 | |
| PCT/US2013/040287 WO2013169989A1 (en) | 2012-05-09 | 2013-05-09 | Method and compounds for inhibiting the mcm complex and their application in cancer treatment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014MN02513A true IN2014MN02513A (ja) | 2015-07-17 |
Family
ID=49551267
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2513MUN2014 IN2014MN02513A (ja) | 2012-05-09 | 2013-05-09 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US11648258B2 (ja) |
| EP (2) | EP4248978A3 (ja) |
| JP (5) | JP2015517500A (ja) |
| CN (2) | CN104736157B (ja) |
| AU (1) | AU2013259486B2 (ja) |
| CA (2) | CA3111702A1 (ja) |
| ES (1) | ES2949335T3 (ja) |
| IN (1) | IN2014MN02513A (ja) |
| WO (1) | WO2013169989A1 (ja) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117756875A (zh) * | 2017-05-19 | 2024-03-26 | 恩康药业科技（广州）有限公司 | 黄夹次甙乙多晶型的晶型特征、制备方法及在抗癌上的应用 |
| AU2019283946B2 (en) * | 2017-05-19 | 2021-05-20 | Enkang Pharmaceuticals (Guangzhou), Ltd. | Crystal characteristics, preparation processes and anticancer applications of 17beta-neriifolin crystal forms |
| CN114177189A (zh) * | 2019-03-27 | 2022-03-15 | 天津中医药大学 | 黄夹次乙苷作为抗肿瘤药物的应用 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0592990A (ja) | 1991-08-06 | 1993-04-16 | Taisho Pharmaceut Co Ltd | カルデノライド誘導体 |
| WO2002014343A1 (en) * | 2000-08-17 | 2002-02-21 | Terness, Peter | Bufadienolide derivatives and use as immunosuppressive, antiinflammatory and analgesic agents |
| US8318922B2 (en) | 2002-08-29 | 2012-11-27 | The Hong Kong Polytechnic University | Treatment and prevention of hyperproliferative conditions in humans and antisense oligonucleotide inhibition of human replication-initiation proteins |
| US7393950B2 (en) | 2002-08-29 | 2008-07-01 | Hong Kong University Of Science & Technology | Antisense oligonucleotides targeted to human CDC45 |
| JP2004131435A (ja) | 2002-10-11 | 2004-04-30 | Mitsubishi Chemicals Corp | 抗癌剤のスクリーニング方法及び組織の癌化の判定方法 |
| DE10248751A1 (de) | 2002-10-18 | 2004-05-06 | Berdel, Wolfgang E., Prof. Dr.med. | Dyslokalisationsmoleküle und deren Verwendung |
| WO2005099747A1 (en) | 2004-04-14 | 2005-10-27 | Medical Research Council | Selective killing of cancer cells by induction of acetyltransferase via tnf-alpha and il-6 |
| EP1833991A4 (en) | 2004-12-22 | 2011-11-16 | Auckland Uniservices Ltd | TREE PEPTIDES AND METHODS FOR TREATING PROLIFERATIVE DISORDERS USING SAID PEPTIDES |
| EP1787645A1 (en) | 2005-11-18 | 2007-05-23 | Institut Curie | New method for treating cancer based on the modulation of the calcineurin and/or the calcineurin/NFAT pathway |
| US20090018088A1 (en) | 2006-10-27 | 2009-01-15 | University Of Louisville Research Foundation | Treating cancer with cardiac glycosides |
| CN101683359B (zh) | 2008-09-28 | 2012-05-09 | 上海秀新臣邦医药科技有限公司 | 一种治疗肿瘤的中药组合物及其制备方法 |
| CN101726577A (zh) * | 2008-10-13 | 2010-06-09 | 中山大学 | 通过干扰巢蛋白表达来筛选抑制肿瘤增殖和促进细胞凋亡的药物的方法 |
| US20110311651A1 (en) | 2008-12-10 | 2011-12-22 | Sloan-Kettering Institute For Cancer Research | Cardenolides for the treatment of ocular cancer |
| CN102219821A (zh) | 2011-05-05 | 2011-10-19 | 沈阳药科大学 | 一类强心苷类化合物及其抗肿瘤用途 |
-
2013
- 2013-05-09 CN CN201380024370.2A patent/CN104736157B/zh active Active
- 2013-05-09 CA CA3111702A patent/CA3111702A1/en not_active Withdrawn
- 2013-05-09 AU AU2013259486A patent/AU2013259486B2/en active Active
- 2013-05-09 IN IN2513MUN2014 patent/IN2014MN02513A/en unknown
- 2013-05-09 CN CN201910489605.4A patent/CN110412285B/zh active Active
- 2013-05-09 US US14/399,960 patent/US11648258B2/en active Active
- 2013-05-09 EP EP23177484.5A patent/EP4248978A3/en active Pending
- 2013-05-09 EP EP13787939.1A patent/EP2846807B1/en active Active
- 2013-05-09 CA CA2873283A patent/CA2873283C/en active Active
- 2013-05-09 WO PCT/US2013/040287 patent/WO2013169989A1/en active Application Filing
- 2013-05-09 JP JP2015511684A patent/JP2015517500A/ja active Pending
- 2013-05-09 ES ES13787939T patent/ES2949335T3/es active Active
-
2018
- 2018-01-11 JP JP2018002988A patent/JP2018100274A/ja active Pending
-
2019
- 2019-12-27 JP JP2019237597A patent/JP2020073544A/ja active Pending
-
2021
- 2021-09-16 JP JP2021150771A patent/JP2021193132A/ja active Pending
-
2023
- 2023-09-21 JP JP2023154199A patent/JP2024001049A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2020073544A (ja) | 2020-05-14 |
| CN104736157A (zh) | 2015-06-24 |
| US11648258B2 (en) | 2023-05-16 |
| CN110412285A (zh) | 2019-11-05 |
| EP4248978A3 (en) | 2023-11-08 |
| ES2949335T3 (es) | 2023-09-27 |
| AU2013259486A1 (en) | 2014-12-18 |
| CA3111702A1 (en) | 2013-11-14 |
| AU2013259486B2 (en) | 2019-12-12 |
| JP2018100274A (ja) | 2018-06-28 |
| EP2846807A4 (en) | 2016-07-27 |
| CN110412285B (zh) | 2022-11-15 |
| CA2873283A1 (en) | 2013-11-14 |
| EP2846807A1 (en) | 2015-03-18 |
| JP2021193132A (ja) | 2021-12-23 |
| CA2873283C (en) | 2021-05-04 |
| EP2846807B1 (en) | 2023-06-07 |
| JP2015517500A (ja) | 2015-06-22 |
| EP4248978A2 (en) | 2023-09-27 |
| WO2013169989A1 (en) | 2013-11-14 |
| JP2024001049A (ja) | 2024-01-09 |
| CN104736157B (zh) | 2019-06-11 |
| EP2846807C0 (en) | 2023-06-07 |
| US20150099712A1 (en) | 2015-04-09 |
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