IN2014MN02156A - - Google Patents

Info

Publication number
IN2014MN02156A
IN2014MN02156A IN2156MUN2014A IN2014MN02156A IN 2014MN02156 A IN2014MN02156 A IN 2014MN02156A IN 2156MUN2014 A IN2156MUN2014 A IN 2156MUN2014A IN 2014MN02156 A IN2014MN02156 A IN 2014MN02156A
Authority
IN
India
Prior art keywords
acid
microparticles
alfentanil
presented
pain
Prior art date
Application number
Other languages
English (en)
Inventor
Anders Pettersson
Emil Schwan
Barbro Johansson
Original Assignee
Orexo Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48577134&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IN2014MN02156(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB1207701.2A external-priority patent/GB201207701D0/en
Priority claimed from GBGB1221130.6A external-priority patent/GB201221130D0/en
Application filed by Orexo Ab filed Critical Orexo Ab
Publication of IN2014MN02156A publication Critical patent/IN2014MN02156A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • A61K9/1623Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IN2156MUN2014 2012-05-02 2013-05-01 IN2014MN02156A (xx)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1207701.2A GB201207701D0 (en) 2012-05-02 2012-05-02 New pharmaceutical composition
GBGB1221130.6A GB201221130D0 (en) 2012-11-23 2012-11-23 New pharmaceutical composition
PCT/GB2013/051131 WO2013164620A1 (en) 2012-05-02 2013-05-01 New alfentanil composition for the treatment of acute pain

Publications (1)

Publication Number Publication Date
IN2014MN02156A true IN2014MN02156A (xx) 2015-08-28

Family

ID=48577134

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2156MUN2014 IN2014MN02156A (xx) 2012-05-02 2013-05-01

Country Status (34)

Country Link
US (4) US8815911B2 (xx)
EP (2) EP3150199B1 (xx)
JP (1) JP6275696B2 (xx)
KR (1) KR20150005695A (xx)
CN (1) CN104427978B (xx)
AU (1) AU2013255640B2 (xx)
BR (1) BR112014027213A8 (xx)
CA (1) CA2871805A1 (xx)
CL (1) CL2014002979A1 (xx)
CO (1) CO7170181A2 (xx)
CY (2) CY1118570T1 (xx)
DK (2) DK3150199T3 (xx)
EA (1) EA028110B1 (xx)
ES (2) ES2614757T3 (xx)
HK (1) HK1203399A1 (xx)
HR (2) HRP20161634T1 (xx)
HU (1) HUE031792T2 (xx)
IL (1) IL235272B (xx)
IN (1) IN2014MN02156A (xx)
LT (2) LT2849730T (xx)
ME (1) ME02644B (xx)
MX (1) MX360665B (xx)
NZ (1) NZ701428A (xx)
PE (1) PE20142444A1 (xx)
PH (1) PH12014502407B1 (xx)
PL (2) PL3150199T3 (xx)
PT (2) PT2849730T (xx)
RS (2) RS55489B1 (xx)
SG (1) SG11201407081PA (xx)
SI (2) SI3150199T1 (xx)
SM (1) SMT201700086B (xx)
TR (1) TR201815935T4 (xx)
WO (1) WO2013164620A1 (xx)
ZA (1) ZA201407559B (xx)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103813785B (zh) 2011-09-19 2017-02-15 奥瑞克索股份公司 新的治疗阿片样物质依赖的抗滥用药物组合物
PL3150199T3 (pl) * 2012-05-02 2019-03-29 Orexo Ab Nowa kompozycja zawierająca alfentanyl do leczenia ostrego bólu
WO2017180659A1 (en) * 2016-04-11 2017-10-19 Arizona Board Of Regents On Behalf Of University Of Arizona Opioid receptor modulators
JP7023054B2 (ja) * 2017-04-05 2022-02-21 東和薬品株式会社 レベチラセタム含有医薬組成物及びその製造方法

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5785989A (en) * 1985-05-01 1998-07-28 University Utah Research Foundation Compositions and methods of manufacturing of oral dissolvable medicaments
US5288497A (en) 1985-05-01 1994-02-22 The University Of Utah Compositions of oral dissolvable medicaments
DE19758564A1 (de) 1997-11-11 1999-08-26 Gruenenthal Gmbh Formulierung einer Kombination aus Morphin und einem alpha¶2¶-adrenergem Agonisten und deren Verwendung
SE9803239D0 (sv) 1998-09-24 1998-09-24 Diabact Ab Composition for the treatment of acute pain
SE9803240D0 (sv) 1998-09-24 1998-09-24 Diabact Ab A pharmaceutical composition having a rapid action
GB9904911D0 (en) 1999-03-03 1999-04-28 Scherer Ltd R P Pharmaceutical compositions
US6264981B1 (en) 1999-10-27 2001-07-24 Anesta Corporation Oral transmucosal drug dosage using solid solution
US20020160043A1 (en) 2001-02-27 2002-10-31 Dennis Coleman Compositions and method of manufacture for oral dissolvable dosage forms
JP4850346B2 (ja) * 2001-03-15 2012-01-11 救急薬品工業株式会社 粘膜貼付剤
US20030068356A1 (en) 2001-07-10 2003-04-10 Pather S. Indiran Sequential drug delivery systems
US20110033542A1 (en) 2009-08-07 2011-02-10 Monosol Rx, Llc Sublingual and buccal film compositions
US20060216352A1 (en) 2003-01-31 2006-09-28 Orexo Ab Rapid-acting pharmaceutical composition
ES2414084T3 (es) 2003-02-24 2013-07-18 Pharmaceutical Productions Inc. Sistema de administración de fármacos por vía transmucosa
US20050042281A1 (en) 2003-08-21 2005-02-24 Singh Nikhilesh N. Compositions for delivering therapeutic agents across the oral mucosa
CA2549642C (en) 2003-12-31 2012-10-30 Cima Labs Inc. Effervescent oral opiate dosage forms and methods of administering opiates
NZ548216A (en) 2003-12-31 2010-02-26 Cima Labs Inc Generally linear effervescent oral fentanyl dosage form and methods of administering
US20070036853A1 (en) 2003-12-31 2007-02-15 Cima Labs Inc. Generally linear effervescent oral fentanyl dosage form and methods of administering
WO2005065317A2 (en) * 2003-12-31 2005-07-21 Cima Labs Inc. Effervescent oral fentanyl dosage form
FR2883179B1 (fr) 2005-03-18 2009-04-17 Ethypharm Sa Comprime enrobe
US20080248110A1 (en) 2005-03-28 2008-10-09 Anders Pettersson Pharmaceutical Compositions Useful in the Treatment of Pain
US20060281775A1 (en) * 2005-06-14 2006-12-14 Applied Pharmacy Services, Inc. Two-component pharmaceutical composition for the treatment of pain
US20070104763A1 (en) * 2005-11-10 2007-05-10 Navinta Llc Composition of fentanyl citrate oral solid transmucosal dosage form, excipient and binding material therefore, and methods of making
US8535714B2 (en) * 2006-01-06 2013-09-17 Acelrx Pharmaceuticals, Inc. Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain
US8865743B2 (en) 2006-01-06 2014-10-21 Acelrx Pharmaceuticals, Inc. Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain
US8202535B2 (en) * 2006-01-06 2012-06-19 Acelrx Pharmaceuticals, Inc. Small-volume oral transmucosal dosage forms
US8252328B2 (en) 2006-01-06 2012-08-28 Acelrx Pharmaceuticals, Inc. Bioadhesive drug formulations for oral transmucosal delivery
US20100233257A1 (en) 2006-06-09 2010-09-16 Ethypharm Low dose sublingual tablets of opioid analgesics and preparation process
US20070286900A1 (en) 2006-06-09 2007-12-13 Catherine Herry Low dose tablets of opioid analgesics and preparation process
NZ594545A (en) * 2006-07-21 2012-12-21 Biodelivery Sciences Int Inc Transmucosal delivery devices with enhanced uptake containing fentanyl or buprenorphine
DK2101740T3 (da) * 2006-12-04 2013-11-18 Orexo Ab Nye ikke-misbrugs-farmaceutiske sammensætninger omfattende opioider
EP1964564A1 (en) 2007-04-19 2008-09-03 LAB International SRL Breakthrough Pain Management
JP5632284B2 (ja) 2007-08-07 2014-11-26 エーセルアールエックス ファーマシューティカルズ, インコーポレイテッド 経口経粘膜剤形を使用する処置時の鎮静および無痛のための組成物および方法
US20090263476A1 (en) * 2008-04-16 2009-10-22 Jobdevairakkam Christopher N Composition of Rapid Disintegrating Direct Compression Buccal Tablet
US8343978B2 (en) 2008-08-04 2013-01-01 Adds Pharmaceuticals Llc Fast onset orodispersable tablets
WO2010027770A1 (en) 2008-09-04 2010-03-11 Mallinckrodt Inc. Crystalline forms of sufentanil citrate
US8945592B2 (en) 2008-11-21 2015-02-03 Acelrx Pharmaceuticals, Inc. Sufentanil solid dosage forms comprising oxygen scavengers and methods of using the same
EP2429503A1 (en) 2009-05-13 2012-03-21 Protein Delivery Solutions, LLC Pharmaceutical system for trans-membrane delivery
WO2010141505A1 (en) 2009-06-01 2010-12-09 Protect Pharmaceutical Corporation Abuse-resistant delivery systems
JP2009280611A (ja) * 2009-08-26 2009-12-03 Kyukyu Yakuhin Kogyo Kk 口腔内粘膜フィルム剤
US20110091544A1 (en) 2009-10-16 2011-04-21 Acelrx Pharmaceuticals, Inc. Compositions and Methods for Mild Sedation, Anxiolysis and Analgesia in the Procedural Setting
WO2011057199A1 (en) 2009-11-06 2011-05-12 Adenios, Inc. Compositions for treating cns disorders
US20110150989A1 (en) 2009-12-22 2011-06-23 Mallinkckrodt Inc. Methods of Producing Stabilized Solid Dosage Pharmaceutical Compositions Containing Morphinans
PL3150199T3 (pl) * 2012-05-02 2019-03-29 Orexo Ab Nowa kompozycja zawierająca alfentanyl do leczenia ostrego bólu

Also Published As

Publication number Publication date
TR201815935T4 (tr) 2018-11-21
CA2871805A1 (en) 2013-11-07
US9345698B2 (en) 2016-05-24
US9782396B2 (en) 2017-10-10
JP2015515974A (ja) 2015-06-04
PT2849730T (pt) 2017-02-15
US20150133501A1 (en) 2015-05-14
MX2014013176A (es) 2015-01-19
PL3150199T3 (pl) 2019-03-29
CY1120820T1 (el) 2019-12-11
IL235272B (en) 2018-10-31
BR112014027213A2 (pt) 2017-06-27
RS57951B1 (sr) 2019-01-31
PL2849730T3 (pl) 2017-05-31
MX360665B (es) 2018-11-13
SI3150199T1 (sl) 2018-12-31
SI2849730T1 (sl) 2017-02-28
CN104427978A (zh) 2015-03-18
HRP20181761T1 (hr) 2018-12-28
EP2849730B1 (en) 2016-11-09
ES2614757T3 (es) 2017-06-01
CL2014002979A1 (es) 2014-12-05
KR20150005695A (ko) 2015-01-14
CO7170181A2 (es) 2015-01-28
HUE031792T2 (en) 2017-07-28
LT2849730T (lt) 2016-12-27
EP2849730A1 (en) 2015-03-25
ME02644B (me) 2017-06-20
EA201401200A1 (ru) 2015-02-27
BR112014027213A8 (pt) 2018-01-16
ZA201407559B (en) 2016-05-25
DK2849730T3 (en) 2017-02-13
WO2013164620A1 (en) 2013-11-07
US20140005223A1 (en) 2014-01-02
NZ701428A (en) 2016-10-28
US20180214437A1 (en) 2018-08-02
SMT201700086B (it) 2017-03-08
HRP20161634T1 (hr) 2017-01-13
EA028110B1 (ru) 2017-10-31
PH12014502407A1 (en) 2015-01-12
LT3150199T (lt) 2018-11-12
SG11201407081PA (en) 2014-11-27
EP3150199A1 (en) 2017-04-05
US8815911B2 (en) 2014-08-26
CN104427978B (zh) 2017-03-01
AU2013255640B2 (en) 2017-06-15
ES2694644T3 (es) 2018-12-26
RS55489B1 (sr) 2017-04-28
JP6275696B2 (ja) 2018-02-14
PH12014502407B1 (en) 2015-01-12
AU2013255640A1 (en) 2014-11-20
PT3150199T (pt) 2018-11-21
US20170071927A1 (en) 2017-03-16
EP3150199B1 (en) 2018-08-08
DK3150199T3 (en) 2018-11-12
HK1203399A1 (en) 2015-10-30
CY1118570T1 (el) 2017-07-12
PE20142444A1 (es) 2015-01-09

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