IN2014MN01637A - - Google Patents
Download PDFInfo
- Publication number
- IN2014MN01637A IN2014MN01637A IN1637MUN2014A IN2014MN01637A IN 2014MN01637 A IN2014MN01637 A IN 2014MN01637A IN 1637MUN2014 A IN1637MUN2014 A IN 1637MUN2014A IN 2014MN01637 A IN2014MN01637 A IN 2014MN01637A
- Authority
- IN
- India
- Prior art keywords
- compound
- represented
- groups
- formula
- description
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/1013—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/005—Enzyme inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/07—Tetrapeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Peptides Or Proteins (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210034872.0A CN102617705B (zh) | 2012-02-16 | 2012-02-16 | 抑制丙肝病毒复制的大环类化合物 |
| PCT/CN2012/085912 WO2013120371A1 (zh) | 2012-02-16 | 2012-12-05 | 抑制丙肝病毒复制的大环类化合物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014MN01637A true IN2014MN01637A (es) | 2015-07-03 |
Family
ID=46557956
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN1637MUN2014 IN2014MN01637A (es) | 2012-02-16 | 2012-12-05 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9321809B2 (es) |
| EP (1) | EP2816054A4 (es) |
| JP (1) | JP6105632B2 (es) |
| KR (1) | KR102004381B1 (es) |
| CN (2) | CN102617705B (es) |
| AU (1) | AU2012370125A1 (es) |
| CA (1) | CA2864488A1 (es) |
| IL (1) | IL233899A0 (es) |
| IN (1) | IN2014MN01637A (es) |
| WO (1) | WO2013120371A1 (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8957203B2 (en) | 2011-05-05 | 2015-02-17 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| CN102617705B (zh) * | 2012-02-16 | 2014-12-31 | 上海纬诺医药科技有限公司 | 抑制丙肝病毒复制的大环类化合物 |
| LT2909205T (lt) | 2012-10-19 | 2016-12-27 | Bristol-Myers Squibb Company | 9-metilpakeistieji heksadekahidrociklopropa(e)pirolo (1,2-a)(1,4)diazaciklopentadecinilkarbamato dariniai, kaip nestruktūrinės 3 (ns3) proteazės inhibitoriai, skirti hepatito c viruso infekcijų gydymui |
| EP2914598B1 (en) | 2012-11-02 | 2017-10-18 | Bristol-Myers Squibb Company | Hepatitis c virus inhibitors |
| US9643999B2 (en) | 2012-11-02 | 2017-05-09 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| WO2014070964A1 (en) | 2012-11-02 | 2014-05-08 | Bristol-Myers Squibb Company | Hepatitis c virus inhibitors |
| WO2014070974A1 (en) | 2012-11-05 | 2014-05-08 | Bristol-Myers Squibb Company | Hepatitis c virus inhibitors |
| CN105164148A (zh) | 2013-03-07 | 2015-12-16 | 百时美施贵宝公司 | 丙型肝炎病毒抑制剂 |
| CN104447952A (zh) * | 2014-12-11 | 2015-03-25 | 上海唐润医药科技有限公司 | 丙肝病毒蛋白酶抑制剂及其合成方法 |
| CN110963986B (zh) * | 2018-09-28 | 2022-03-29 | 北京瑞莱博基医药科技有限公司 | 一种糖尿病治疗药物中间体的合成工艺 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2369711A1 (en) * | 2002-01-30 | 2003-07-30 | Boehringer Ingelheim (Canada) Ltd. | Macrocyclic peptides active against the hepatitis c virus |
| US7592419B2 (en) * | 2003-09-26 | 2009-09-22 | Schering Corporation | Macrocyclic inhibitors of hepatitis C virus NS3-serine protease |
| UA90909C2 (en) * | 2005-07-20 | 2010-06-10 | Мерк Шарп Энд Домэ Корп. | Hcv ns3 protease inhibitors |
| TWI387603B (zh) | 2005-07-20 | 2013-03-01 | Merck Sharp & Dohme | Ｈｃｖ ｎｓ３蛋白酶抑制劑 |
| GB0612423D0 (en) * | 2006-06-23 | 2006-08-02 | Angeletti P Ist Richerche Bio | Therapeutic agents |
| US8138164B2 (en) | 2006-10-24 | 2012-03-20 | Merck Sharp & Dohme Corp. | HCV NS3 protease inhibitors |
| US7964560B2 (en) * | 2008-05-29 | 2011-06-21 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| WO2010033466A1 (en) * | 2008-09-16 | 2010-03-25 | Phenomix Corporation | Macrocyclic inhibitors of hepatitis c protease |
| MX2011006631A (es) * | 2008-12-19 | 2011-09-06 | Gilead Sciences Inc | Inhibidores de proteasa ns3 del virus hcv. |
| MX2011012155A (es) * | 2009-05-13 | 2012-02-28 | Enanta Pharm Inc | Compuestos macrociclicos como inhibidores del virus de hepatitis c. |
| WO2011009961A1 (en) * | 2009-07-24 | 2011-01-27 | Virologik Gmbh | Combination of proteasome inhibitors and anti-hepatitis medication for treating hepatitis |
| CN102617705B (zh) * | 2012-02-16 | 2014-12-31 | 上海纬诺医药科技有限公司 | 抑制丙肝病毒复制的大环类化合物 |
-
2012
- 2012-02-16 CN CN201210034872.0A patent/CN102617705B/zh not_active Expired - Fee Related
- 2012-12-05 CA CA2864488A patent/CA2864488A1/en not_active Abandoned
- 2012-12-05 AU AU2012370125A patent/AU2012370125A1/en not_active Abandoned
- 2012-12-05 KR KR1020147022579A patent/KR102004381B1/ko active IP Right Grant
- 2012-12-05 IN IN1637MUN2014 patent/IN2014MN01637A/en unknown
- 2012-12-05 EP EP12868766.2A patent/EP2816054A4/en not_active Withdrawn
- 2012-12-05 JP JP2014556905A patent/JP6105632B2/ja not_active Expired - Fee Related
- 2012-12-05 WO PCT/CN2012/085912 patent/WO2013120371A1/zh active Application Filing
- 2012-12-05 US US14/375,418 patent/US9321809B2/en not_active Expired - Fee Related
- 2012-12-05 CN CN201280069837.0A patent/CN104169293A/zh active Pending
-
2014
- 2014-07-31 IL IL233899A patent/IL233899A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL233899A0 (en) | 2014-09-30 |
| EP2816054A1 (en) | 2014-12-24 |
| JP6105632B2 (ja) | 2017-03-29 |
| EP2816054A4 (en) | 2015-07-29 |
| CN102617705A (zh) | 2012-08-01 |
| JP2015508761A (ja) | 2015-03-23 |
| CN104169293A (zh) | 2014-11-26 |
| US20150031603A1 (en) | 2015-01-29 |
| AU2012370125A1 (en) | 2014-07-31 |
| CA2864488A1 (en) | 2013-08-22 |
| WO2013120371A1 (zh) | 2013-08-22 |
| US9321809B2 (en) | 2016-04-26 |
| KR102004381B1 (ko) | 2019-10-01 |
| CN102617705B (zh) | 2014-12-31 |
| KR20140134273A (ko) | 2014-11-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IN2014MN01637A (es) | ||
| PH12016501375A1 (en) | Pyridin-2-amides useful as cb2 agonists | |
| UA113643C2 (xx) | N-цикліламіди як нематоциди | |
| EA201590321A1 (ru) | Дейтерированный барицитиниб | |
| MX2014015287A (es) | Derivado del ester del acido heteroarilcarboxilico. | |
| IN2015DN00202A (es) | ||
| MY179412A (en) | Pyridine-2-amides useful as cb2 agonists | |
| MY163187A (en) | Novel imidazo-oxazine compound or salt thereof | |
| IN2015DN01035A (es) | ||
| EA201290800A1 (ru) | Гетероциклическое соединение | |
| IN2015DN00598A (es) | ||
| MY182328A (en) | Pyridine-2-amides useful as cb2 agonists | |
| CR20130539A (es) | Triazolopiridinas | |
| IN2012DE00621A (es) | ||
| UY34442A (es) | 2-tiopirimidinonas. | |
| IN2015DN00446A (es) | ||
| IN2012DE00620A (es) | ||
| MX349373B (es) | Nuevos derivados de pirazina. | |
| PH12015502665A1 (en) | Improvements in or relating to organic compounds | |
| MX352654B (es) | Amidas macrociclicas como inhibidores de proteasas. | |
| CY1121116T1 (el) | Νεα μεθοδος για την συνθεση αγομελατινης | |
| MX2014008918A (es) | Nuevos derivados de pirrolidina. | |
| MX342960B (es) | Derivados de cromeno. | |
| MX2015016766A (es) | Nuevos derivados de tetrazolona. | |
| PH12014501676A1 (en) | Plant disease control composition |