IN2014DN10889A - - Google Patents
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- Publication number
- IN2014DN10889A IN2014DN10889A IN10889DEN2014A IN2014DN10889A IN 2014DN10889 A IN2014DN10889 A IN 2014DN10889A IN 10889DEN2014 A IN10889DEN2014 A IN 10889DEN2014A IN 2014DN10889 A IN2014DN10889 A IN 2014DN10889A
- Authority
- IN
- India
- Prior art keywords
- cell
- car
- conjugate
- drug
- molecule
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6849—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a receptor, a cell surface antigen or a cell surface determinant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/77—Internalization into the cell
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261671518P | 2012-07-13 | 2012-07-13 | |
PCT/US2013/050272 WO2014011987A1 (en) | 2012-07-13 | 2013-07-12 | Compositions and methods for regulating car t cells |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2014DN10889A true IN2014DN10889A (ja) | 2015-09-11 |
Family
ID=49916567
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN10889DEN2014 IN2014DN10889A (ja) | 2012-07-13 | 2013-07-12 |
Country Status (14)
Country | Link |
---|---|
US (3) | US20150140019A1 (ja) |
EP (1) | EP2872218A4 (ja) |
JP (1) | JP2015525765A (ja) |
KR (1) | KR20150030724A (ja) |
CN (1) | CN104507537A (ja) |
AU (1) | AU2013289970A1 (ja) |
BR (1) | BR112015000310A2 (ja) |
CA (1) | CA2878856A1 (ja) |
EA (1) | EA201590207A1 (ja) |
IL (1) | IL236679A0 (ja) |
IN (1) | IN2014DN10889A (ja) |
MX (1) | MX2015000428A (ja) |
SG (1) | SG11201408398UA (ja) |
WO (1) | WO2014011987A1 (ja) |
Families Citing this family (88)
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WO2015112626A1 (en) | 2014-01-21 | 2015-07-30 | June Carl H | Enhanced antigen presenting ability of car t cells by co-introduction of costimulatory molecules |
RU2718542C2 (ru) | 2014-04-07 | 2020-04-08 | Новартис Аг | Лечение злокачественной опухоли с использованием химерного рецептора антигена против cd19 |
US11542488B2 (en) | 2014-07-21 | 2023-01-03 | Novartis Ag | Sortase synthesized chimeric antigen receptors |
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WO2016073875A1 (en) * | 2014-11-06 | 2016-05-12 | University Of Maryland, Baltimore | CD8α AND T CELL RECEPTOR VARIANTS AND METHODS OF USING SAME IN MODULATING IMMUNE CELL RESPONSES |
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US10993997B2 (en) | 2014-12-19 | 2021-05-04 | The Broad Institute, Inc. | Methods for profiling the t cell repertoire |
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JP2022547570A (ja) | 2019-09-12 | 2022-11-14 | ザ・ブロード・インスティテュート・インコーポレイテッド | 操作済みのアデノ随伴ウイルスキャプシド |
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US4792447A (en) * | 1981-07-23 | 1988-12-20 | Board Of Regents, The University Of Texas System | Anti-immunoglobulin toxin conjugates useful in the treatment of B cell tumors |
US5977316A (en) * | 1995-01-17 | 1999-11-02 | The Board Of Trustees Of The University Of Kentucky | Monoclonal antibody 1A7 and related polypeptides |
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US7514537B2 (en) * | 2001-04-30 | 2009-04-07 | City Of Hope | Chimeric immunoreceptor useful in treating human gliomas |
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EP1928912A4 (en) * | 2005-09-07 | 2010-02-24 | Medimmune Inc | EPH ANTI-RECEPTOR ANTIBODIES CONJUGATED TO TOXINS |
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DE102010039018B4 (de) * | 2010-08-06 | 2013-02-28 | Technische Universität Dresden | Anti-La Antikörper und ihre Anwendung zum Immunotargeting |
JP5947311B2 (ja) * | 2010-12-09 | 2016-07-06 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | 癌を治療するためのキメラ抗原受容体改変t細胞の使用 |
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-
2013
- 2013-07-12 AU AU2013289970A patent/AU2013289970A1/en not_active Abandoned
- 2013-07-12 MX MX2015000428A patent/MX2015000428A/es unknown
- 2013-07-12 WO PCT/US2013/050272 patent/WO2014011987A1/en active Application Filing
- 2013-07-12 JP JP2015521840A patent/JP2015525765A/ja active Pending
- 2013-07-12 US US14/408,851 patent/US20150140019A1/en not_active Abandoned
- 2013-07-12 CA CA2878856A patent/CA2878856A1/en not_active Abandoned
- 2013-07-12 BR BR112015000310A patent/BR112015000310A2/pt not_active Application Discontinuation
- 2013-07-12 CN CN201380037380.XA patent/CN104507537A/zh active Pending
- 2013-07-12 SG SG11201408398UA patent/SG11201408398UA/en unknown
- 2013-07-12 KR KR20157000921A patent/KR20150030724A/ko not_active Application Discontinuation
- 2013-07-12 EP EP13816421.5A patent/EP2872218A4/en not_active Withdrawn
- 2013-07-12 IN IN10889DEN2014 patent/IN2014DN10889A/en unknown
- 2013-07-12 EA EA201590207A patent/EA201590207A1/ru unknown
-
2015
- 2015-01-12 IL IL236679A patent/IL236679A0/en unknown
-
2018
- 2018-12-11 US US16/216,460 patent/US20190367610A1/en not_active Abandoned
-
2022
- 2022-05-03 US US17/735,624 patent/US20230034117A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
CA2878856A1 (en) | 2014-01-16 |
SG11201408398UA (en) | 2015-02-27 |
IL236679A0 (en) | 2015-02-26 |
US20190367610A1 (en) | 2019-12-05 |
US20150140019A1 (en) | 2015-05-21 |
EP2872218A1 (en) | 2015-05-20 |
US20230034117A1 (en) | 2023-02-02 |
EA201590207A1 (ru) | 2015-05-29 |
AU2013289970A1 (en) | 2015-01-22 |
EP2872218A4 (en) | 2016-07-06 |
WO2014011987A1 (en) | 2014-01-16 |
MX2015000428A (es) | 2015-03-12 |
BR112015000310A2 (pt) | 2017-06-27 |
CN104507537A (zh) | 2015-04-08 |
JP2015525765A (ja) | 2015-09-07 |
KR20150030724A (ko) | 2015-03-20 |
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