IN2014DN09097A - - Google Patents

Info

Publication number
IN2014DN09097A
IN2014DN09097A IN9097DEN2014A IN2014DN09097A IN 2014DN09097 A IN2014DN09097 A IN 2014DN09097A IN 9097DEN2014 A IN9097DEN2014 A IN 9097DEN2014A IN 2014DN09097 A IN2014DN09097 A IN 2014DN09097A
Authority
IN
India
Prior art keywords
antibodies
crystallization
methods
disclosure relates
culture supernatant
Prior art date
Application number
Other languages
English (en)
Inventor
Dariusch Hekmat
Bernhard Helk
Henk Konrad Schulz
Benjamin Smejkal
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of IN2014DN09097A publication Critical patent/IN2014DN09097A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/30—Extraction; Separation; Purification by precipitation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/005—Selection of auxiliary, e.g. for control of crystallisation nuclei, of crystal growth, of adherence to walls; Arrangements for introduction thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/30—Extraction; Separation; Purification by precipitation
    • C07K1/306—Extraction; Separation; Purification by precipitation by crystallization
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/16—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from plants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/54—Improvements relating to the production of bulk chemicals using solvents, e.g. supercritical solvents or ionic liquids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Botany (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IN9097DEN2014 2012-05-11 2013-05-10 IN2014DN09097A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261645855P 2012-05-11 2012-05-11
PCT/EP2013/059696 WO2013167720A1 (en) 2012-05-11 2013-05-10 Crystallization methods for purification of monoclonal antibodies

Publications (1)

Publication Number Publication Date
IN2014DN09097A true IN2014DN09097A (ja) 2015-05-22

Family

ID=48326319

Family Applications (1)

Application Number Title Priority Date Filing Date
IN9097DEN2014 IN2014DN09097A (ja) 2012-05-11 2013-05-10

Country Status (14)

Country Link
US (2) US20150133642A1 (ja)
EP (1) EP2846830A1 (ja)
JP (1) JP2015517306A (ja)
KR (1) KR20150016503A (ja)
CN (1) CN104284676B (ja)
AU (1) AU2013258006B2 (ja)
BR (1) BR112014027994A2 (ja)
CA (1) CA2872145A1 (ja)
IL (1) IL235483A0 (ja)
IN (1) IN2014DN09097A (ja)
MX (1) MX2014013754A (ja)
RU (1) RU2014150071A (ja)
SG (1) SG11201406664SA (ja)
WO (1) WO2013167720A1 (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3015542A1 (de) * 2015-05-07 2016-05-04 Bayer Technology Services GmbH Modulare anlage und verfahren zur kontinuierlichen, keimreduzierten produktion und/oder aufbereitung eines produktes
EP3858145A1 (en) * 2016-12-23 2021-08-04 Arla Foods amba Production of novel beta-lactoglobulin preparations and related methods, uses, and food products
DK3596101T3 (da) * 2017-03-14 2022-03-14 Amgen Inc Fremgangsmåder rettet mod krystallinske biomolekyler
IT202100004496A1 (it) 2021-02-25 2022-08-25 Univ Della Calabria Recupero di farmaci biologici o loro frammenti da soluzioni impure mediante cristallizzazione o precipitazione con membrane
CN116949036B (zh) * 2023-09-11 2023-12-15 成都斯马特科技有限公司 一种快速从腹水中提取核酸的试剂盒及提取方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20100031769A (ko) * 2000-12-28 2010-03-24 알투스 파마슈티컬스 인코포레이티드 전항체 및 이의 단편의 결정과 이의 제조 및 사용 방법
DE60237841D1 (de) * 2001-11-13 2010-11-11 Genentech Inc Zusammensetzungen basierend auf APO2-Ligand/ TRAIL und ihre Verwendung
US7087719B2 (en) * 2002-11-19 2006-08-08 Gtc Biotherapeutics, Inc. Method for the crystallization of human serum albumin
AU2008343347A1 (en) * 2007-12-21 2009-07-09 Genentech, Inc. Crystallization of anti-CD20 antibodies
CN101320006B (zh) * 2008-07-17 2010-12-01 西北工业大学 蛋白质结晶条件的筛选方法

Also Published As

Publication number Publication date
AU2013258006B2 (en) 2016-04-28
EP2846830A1 (en) 2015-03-18
US20150133642A1 (en) 2015-05-14
CN104284676B (zh) 2018-11-27
KR20150016503A (ko) 2015-02-12
SG11201406664SA (en) 2014-11-27
US20170198028A1 (en) 2017-07-13
BR112014027994A2 (pt) 2017-06-27
CA2872145A1 (en) 2013-11-14
JP2015517306A (ja) 2015-06-22
WO2013167720A1 (en) 2013-11-14
AU2013258006A1 (en) 2014-11-06
CN104284676A (zh) 2015-01-14
RU2014150071A (ru) 2016-07-10
MX2014013754A (es) 2015-02-12
IL235483A0 (en) 2014-12-31

Similar Documents

Publication Publication Date Title
PH12014501427B1 (en) Anti-phf-tau antibodies and their uses
HRP20190484T1 (hr) Pripravci stanične kulture i postupci proizvodnje polipeptida
IN2014CN03887A (ja)
CL2016001190A1 (es) Cultivo de células de mamífero.
HK1199905A1 (en) Culturing of mesenchymal stem cells
SG11201505192RA (en) Chromatographic purification of antibodies from chromatin-deficient cell culture harvests
EP2968549A4 (en) CELL CULTURE METHODS
EP2982742A4 (en) PHOTOBIOREACTOR FOR THE MASS CULTIVATION OF PHOTOSYNTHESEMICROORGANISM
IN2014CN02639A (ja)
EP2971014A4 (en) CELL CULTURE METHODS
EP2971040A4 (en) CELL CULTURE METHODS
EP2893001A4 (en) METHOD OF CULTURING MESENCHYMAL STEM CELLS
IN2014DN08481A (ja)
GB201103836D0 (en) Conjugation process
NZ703973A (en) Complex chromosome engineering for production of human antibodies in transgenic animals
HK1211977A1 (en) Reactor for bulk production of photosynthetic microorganisms
MX366112B (es) Medio de cultivo celular y metodos de produccion de anticuerpos.
EP2825633A4 (en) PROCESS FOR BREEDING E. COLI CELLS FOR HIGH DENSITY
MY167584A (en) Method for producing ethanol
IN2014DN09097A (ja)
HK1223979A1 (zh) 通過毒胡蘿蔔細胞懸浮培養生產毒胡蘿蔔素
ZA201504388B (en) Method for culturing pluripotent stem cells
MX2012010443A (es) Proceso para la preparacion de 1-alquiltetrazoles 5-sustituidos.
SG11201601182QA (en) Method for the clarification of high density crude cell culture harvest
GB201321679D0 (en) Method of culturing vero cells